{"id":"https://openalex.org/W3211677758","doi":"https://doi.org/10.1016/j.cbpa.2021.102095","title":"Protein metalation in biology","display_name":"Protein metalation in biology","publication_year":2021,"publication_date":"2021-11-08","ids":{"openalex":"https://openalex.org/W3211677758","doi":"https://doi.org/10.1016/j.cbpa.2021.102095","mag":"3211677758","pmid":"https://pubmed.ncbi.nlm.nih.gov/34763208","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8867077"},"language":"en","primary_location":{"id":"doi:10.1016/j.cbpa.2021.102095","doi":"https://doi.org/10.1016/j.cbpa.2021.102095","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cbpa.2021.102095","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1367593121001253/pdf","source":{"id":"https://openalex.org/S35563517","display_name":"Current Opinion in Chemical Biology","issn_l":"1367-5931","issn":["1367-5931","1879-0402"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Chemical Biology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S1367593121001253/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050744899","display_name":"Andrew W. Foster","orcid":"https://orcid.org/0000-0001-7525-0280","observed_orcids":["https://orcid.org/0000-0001-7525-0280"]},"institutions":[{"id":"https://openalex.org/I190082696","display_name":"Durham University","ror":"https://ror.org/01v29qb04","country_code":"GB","type":"education","lineage":["https://openalex.org/I190082696"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew W. Foster","raw_affiliation_strings":["Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK","Department of Biosciences, Durham University, Durham, DH1 3LE, UK","Department of Chemistry, Durham University, Durham, DH1 3LE, UK"],"raw_orcid":"https://orcid.org/0000-0001-7525-0280","affiliations":[{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Chemistry, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010219322","display_name":"Tessa R. Young","orcid":"https://orcid.org/0000-0002-7373-1969","observed_orcids":["https://orcid.org/0000-0002-7373-1969"]},"institutions":[{"id":"https://openalex.org/I190082696","display_name":"Durham University","ror":"https://ror.org/01v29qb04","country_code":"GB","type":"education","lineage":["https://openalex.org/I190082696"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tessa R. Young","raw_affiliation_strings":["Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK","Department of Biosciences, Durham University, Durham, DH1 3LE, UK","Department of Chemistry, Durham University, Durham, DH1 3LE, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Chemistry, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039669658","display_name":"Peter T. Chivers","orcid":"https://orcid.org/0000-0002-8779-1452","observed_orcids":["https://orcid.org/0000-0002-8779-1452"]},"institutions":[{"id":"https://openalex.org/I190082696","display_name":"Durham University","ror":"https://ror.org/01v29qb04","country_code":"GB","type":"education","lineage":["https://openalex.org/I190082696"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter T. Chivers","raw_affiliation_strings":["Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK","Department of Biosciences, Durham University, Durham, DH1 3LE, UK","Department of Chemistry, Durham University, Durham, DH1 3LE, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Chemistry, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058467039","display_name":"Nigel J. Robinson","orcid":"https://orcid.org/0000-0001-5586-1092","observed_orcids":["https://orcid.org/0000-0001-5586-1092"]},"institutions":[{"id":"https://openalex.org/I190082696","display_name":"Durham University","ror":"https://ror.org/01v29qb04","country_code":"GB","type":"education","lineage":["https://openalex.org/I190082696"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Nigel J. Robinson","raw_affiliation_strings":["Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK. Electronic address: nigel.robinson@durham.ac.uk","Department of Biosciences, Durham University, Durham, DH1 3LE, UK","Department of Chemistry, Durham University, Durham, DH1 3LE, UK"],"raw_orcid":"https://orcid.org/0000-0001-5586-1092","affiliations":[{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK; Department of Chemistry, Durham University, Durham, DH1 3LE, UK. Electronic address: nigel.robinson@durham.ac.uk","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Biosciences, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]},{"raw_affiliation_string":"Department of Chemistry, Durham University, Durham, DH1 3LE, UK","institution_ids":["https://openalex.org/I190082696"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5058467039"],"corresponding_institution_ids":["https://openalex.org/I190082696"],"apc_list":{"value":4520,"currency":"USD","value_usd":4520},"apc_paid":{"value":4520,"currency":"USD","value_usd":4520},"fwci":1.8187,"has_fulltext":true,"cited_by_count":91,"citation_normalized_percentile":{"value":0.85799359,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"66","issue":null,"first_page":"102095","last_page":"102095"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.7085000276565552,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.7085000276565552,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.12370000034570694,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.06080000102519989,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metal-homeostasis","display_name":"metal homeostasis","score":0.9520000219345093},{"id":"https://openalex.org/keywords/metal-ion-binding-affinity","display_name":"metal binding affinity","score":0.5830000042915344},{"id":"https://openalex.org/keywords/metal-binding-sites","display_name":"metal binding sites","score":0.48899999260902405},{"id":"https://openalex.org/keywords/metal-competition","display_name":"metal competition","score":0.34700000286102295},{"id":"https://openalex.org/keywords/exchangeable-metals","display_name":"exchangeable metals","score":0.6790000200271606},{"id":"https://openalex.org/keywords/metalloproteins","display_name":"metalloproteins","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2775855785","wikidata":"https://www.wikidata.org/wiki/Q2270356","display_name":"Metalation","level":2,"score":0.9322112798690796},{"id":"https://openalex.org/C544153396","wikidata":"https://www.wikidata.org/wiki/Q11426","display_name":"Metal","level":2,"score":0.5370064973831177},{"id":"https://openalex.org/C171852809","wikidata":"https://www.wikidata.org/wiki/Q731154","display_name":"Chemical biology","level":2,"score":0.5104174017906189},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.496808797121048},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.4735875725746155},{"id":"https://openalex.org/C51639874","wikidata":"https://www.wikidata.org/wiki/Q167149","display_name":"Plasma protein binding","level":2,"score":0.47337573766708374},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.450494647026062},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42994821071624756},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4289343059062958},{"id":"https://openalex.org/C17165728","wikidata":"https://www.wikidata.org/wiki/Q423350","display_name":"Metalloprotein","level":3,"score":0.41625407338142395},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.32810211181640625},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.16409310698509216},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001695","descriptor_name":"Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003035","descriptor_name":"Cobalt","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003300","descriptor_name":"Copper","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008345","descriptor_name":"Manganese","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008670","descriptor_name":"Metals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015032","descriptor_name":"Zinc","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.cbpa.2021.102095","doi":"https://doi.org/10.1016/j.cbpa.2021.102095","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cbpa.2021.102095","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1367593121001253/pdf","source":{"id":"https://openalex.org/S35563517","display_name":"Current Opinion in Chemical Biology","issn_l":"1367-5931","issn":["1367-5931","1879-0402"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Chemical Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8867077","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8867077","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Opin Chem Biol","raw_type":"Text"},{"id":"pmid:34763208","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34763208","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in chemical biology","raw_type":"Journal Article"},{"id":"pmh:oai:dro.dur.ac.uk.OAI2:34838","doi":null,"is_oa":true,"landing_page_url":"http://dro.dur.ac.uk/34838/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400188","display_name":"Durham Research Online (Durham University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I190082696","host_organization_name":"Durham University","host_organization_lineage":["https://openalex.org/I190082696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Current Opinion in Chemical Biology, 2022, Vol.66, pp.102095 [Peer Reviewed Journal]","raw_type":"Article"},{"id":"pmh:oai:https://durham-repository.worktribe.com/:1223962","doi":null,"is_oa":true,"landing_page_url":"https://durham-repository.worktribe.com/output/1223962","pdf_url":"https://durham-repository.worktribe.com/file/1223962/1/Published%20Journal%20Article","source":{"id":"https://openalex.org/S4306400188","display_name":"Durham Research Online (Durham University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I190082696","host_organization_name":"Durham University","host_organization_lineage":["https://openalex.org/I190082696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.cbpa.2021.102095","doi":"https://doi.org/10.1016/j.cbpa.2021.102095","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cbpa.2021.102095","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1367593121001253/pdf","source":{"id":"https://openalex.org/S35563517","display_name":"Current Opinion in Chemical Biology","issn_l":"1367-5931","issn":["1367-5931","1879-0402"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Chemical Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4319555360","display_name":"A calculator for metalation inside a cell","funder_award_id":"BB/V006002/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G5449118981","display_name":"Elements of Bioremediation, Biomanufacturing & Bioenergy (E3B): Metals in Biology","funder_award_id":"BB/S009787/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G696980217","display_name":"METALLOCHAPERONES: The partitioning of metals to delivery pathways","funder_award_id":"BB/R002118/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3211677758.pdf","grobid_xml":"https://content.openalex.org/works/W3211677758.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W106223738","https://openalex.org/W1503466211","https://openalex.org/W1511264100","https://openalex.org/W1616066464","https://openalex.org/W1874817087","https://openalex.org/W1966459102","https://openalex.org/W1967859158","https://openalex.org/W1988829946","https://openalex.org/W1996156164","https://openalex.org/W2017980572","https://openalex.org/W2018180248","https://openalex.org/W2025454110","https://openalex.org/W2035594105","https://openalex.org/W2049336067","https://openalex.org/W2061040884","https://openalex.org/W2070042354","https://openalex.org/W2074842308","https://openalex.org/W2077883858","https://openalex.org/W2079115107","https://openalex.org/W2106462936","https://openalex.org/W2130583217","https://openalex.org/W2147431408","https://openalex.org/W2172320903","https://openalex.org/W2587553267","https://openalex.org/W2597506409","https://openalex.org/W2767581071","https://openalex.org/W2768348732","https://openalex.org/W2790588782","https://openalex.org/W2797396541","https://openalex.org/W2897349895","https://openalex.org/W2911831757","https://openalex.org/W2952701327","https://openalex.org/W2954163989","https://openalex.org/W2957641860","https://openalex.org/W2970405392","https://openalex.org/W2991327056","https://openalex.org/W2995999097","https://openalex.org/W2998838427","https://openalex.org/W3015050560","https://openalex.org/W3020494352","https://openalex.org/W3048780446","https://openalex.org/W3087946339","https://openalex.org/W3088534076","https://openalex.org/W3091007690","https://openalex.org/W3092359591","https://openalex.org/W3109532390","https://openalex.org/W3123090367","https://openalex.org/W3131516802","https://openalex.org/W3157690520","https://openalex.org/W3170306187","https://openalex.org/W3184756130","https://openalex.org/W6796756259","https://openalex.org/W6798786372"],"related_works":["https://openalex.org/W4296400863","https://openalex.org/W3017638657","https://openalex.org/W150547940","https://openalex.org/W3108592907","https://openalex.org/W7220725568","https://openalex.org/W4406552771","https://openalex.org/W1983156335","https://openalex.org/W4247586405","https://openalex.org/W2016649672","https://openalex.org/W2019190661"],"abstract_inverted_index":{"Inorganic":[0],"metals":[1,15,30],"supplement":[2],"the":[3,13,76,85],"chemical":[4],"repertoire":[5],"of":[6,28,42,50,57,78,87],"organic":[7],"molecules,":[8],"especially":[9],"proteins.":[10],"This":[11],"requires":[12],"correct":[14],"to":[16,71,81,89],"associate":[17],"with":[18],"proteins":[19],"at":[20],"metalation.":[21],"Protein":[22],"mismetalation":[23],"typically":[24,45],"occurs":[25],"when":[26],"excesses":[27,41],"unbound":[29],"compete":[31,46],"for":[32,47],"a":[33,82],"binding":[34,80,88],"site":[35],"ex":[36],"vivo.":[37],"However,":[38],"in":[39,65],"biology,":[40],"metal-binding":[43],"sites":[44,91],"limiting":[48],"amounts":[49],"exchangeable":[51],"metals.":[52],"Here,":[53],"we":[54],"summarise":[55],"mechanisms":[56],"metal":[58,63,79],"homeostasis":[59],"that":[60],"sustain":[61],"optimal":[62],"availabilities":[64],"biology.":[66],"We":[67],"describe":[68],"recent":[69],"progress":[70],"understand":[72],"metalation":[73],"by":[74],"comparing":[75],"strength":[77,86],"protein":[83],"versus":[84],"competing":[90],"inside":[92],"cells.":[93]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":25},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":16}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-11-22T00:00:00"}