{"id":"https://openalex.org/W3210504348","doi":"https://doi.org/10.1097/qad.0000000000003102","title":"Impact of long-acting therapies on the global HIV epidemic","display_name":"Impact of long-acting therapies on the global HIV epidemic","publication_year":2021,"publication_date":"2021-10-23","ids":{"openalex":"https://openalex.org/W3210504348","doi":"https://doi.org/10.1097/qad.0000000000003102","mag":"3210504348","pmid":"https://pubmed.ncbi.nlm.nih.gov/34848580"},"language":"en","primary_location":{"id":"doi:10.1097/qad.0000000000003102","doi":"https://doi.org/10.1097/qad.0000000000003102","is_oa":true,"landing_page_url":"https://doi.org/10.1097/qad.0000000000003102","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1097/qad.0000000000003102","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068907159","display_name":"Nomathemba C. Chandiwana","orcid":"https://orcid.org/0000-0001-7866-2651","observed_orcids":["https://orcid.org/0000-0001-7866-2651"]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":true,"raw_author_name":"Nomathemba C. Chandiwana","raw_affiliation_strings":["Ezintsha, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ezintsha, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Celicia M. Serenata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Celicia M. Serenata","raw_affiliation_strings":["Ezintsha, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ezintsha, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andrew Owen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew Owen","raw_affiliation_strings":["Department of Molecular and Clinical Pharmacology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Clinical Pharmacology","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Steve Rannard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I4405260362","display_name":"Centre of Excellence for Long-acting Therapeutics","ror":"https://ror.org/03mmsx307","country_code":"GB","type":"facility","lineage":["https://openalex.org/I146655781","https://openalex.org/I4405260362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Steve Rannard","raw_affiliation_strings":["Department of Chemistry, Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, United Kingdom","institution_ids":["https://openalex.org/I146655781","https://openalex.org/I4405260362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017783904","display_name":"Carmen P\u00e9rez Casas","orcid":"https://orcid.org/0000-0001-8993-0658","observed_orcids":["https://orcid.org/0000-0001-8993-0658"]},"institutions":[{"id":"https://openalex.org/I4210160684","display_name":"Unitaid","ror":"https://ror.org/05t99je22","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210160684"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Carmen P\u00e9rez Casas","raw_affiliation_strings":["Unitaid, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unitaid, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210160684"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cherise Scott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160684","display_name":"Unitaid","ror":"https://ror.org/05t99je22","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210160684"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Cherise Scott","raw_affiliation_strings":["Unitaid, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unitaid, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210160684"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andrew Hill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Hill","raw_affiliation_strings":["Department of Translational Medicine, Liverpool University, Liverpool"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Medicine, Liverpool University, Liverpool","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Polly Clayden","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Polly Clayden","raw_affiliation_strings":["HIV i-Base, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV i-Base, London, United Kingdom","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Charles Flexner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles Flexner","raw_affiliation_strings":["Divisions of Clinical Pharmacology and Infectious Diseases, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisions of Clinical Pharmacology and Infectious Diseases, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5068907159"],"corresponding_institution_ids":["https://openalex.org/I192619145"],"apc_list":null,"apc_paid":null,"fwci":2.3816,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.91373306,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"35","issue":"Supplement 2","first_page":"S137","last_page":"S143"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0215000007301569,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14334","display_name":"HIV/AIDS Impact and Responses","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-pre-exposure-prophylaxis","display_name":"HIV pre-exposure prophylaxis","score":0.8289999961853027},{"id":"https://openalex.org/keywords/hiv-treatment","display_name":"HIV treatment","score":0.8119999766349792},{"id":"https://openalex.org/keywords/hiv-aids-epidemic","display_name":"HIV/AIDS epidemic","score":0.6050000190734863},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"low- and middle-income countries","score":0.8619999885559082},{"id":"https://openalex.org/keywords/scalable-fabrication","display_name":"scalable fabrication","score":0.7239999771118164},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.7379999756813049},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.7599999904632568},{"id":"https://openalex.org/keywords/oral-antiretroviral-therapy","display_name":"oral antiretroviral therapy","score":0.7540000081062317},{"id":"https://openalex.org/keywords/hiv-prevention","display_name":"HIV prevention","score":0.6150000095367432}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.753000020980835},{"id":"https://openalex.org/C2777288759","wikidata":"https://www.wikidata.org/wiki/Q4164182","display_name":"Dosing","level":2,"score":0.6506999731063843},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6383000016212463},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.6158999800682068},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.574400007724762},{"id":"https://openalex.org/C2777931914","wikidata":"https://www.wikidata.org/wiki/Q24975420","display_name":"Treatment as prevention","level":5,"score":0.4489000141620636},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.43050000071525574},{"id":"https://openalex.org/C2909254382","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"ANTIRETROVIRAL AGENTS","level":5,"score":0.4251999855041504},{"id":"https://openalex.org/C83864248","wikidata":"https://www.wikidata.org/wiki/Q177323","display_name":"Developing country","level":2,"score":0.4000999927520752},{"id":"https://openalex.org/C160050368","wikidata":"https://www.wikidata.org/wiki/Q132453","display_name":"Developed country","level":3,"score":0.39579999446868896},{"id":"https://openalex.org/C46578552","wikidata":"https://www.wikidata.org/wiki/Q2725393","display_name":"Global health","level":3,"score":0.3644999861717224},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.34869998693466187},{"id":"https://openalex.org/C3018472363","wikidata":"https://www.wikidata.org/wiki/Q177323","display_name":"Low and middle income countries","level":3,"score":0.32260000705718994},{"id":"https://openalex.org/C168285401","wikidata":"https://www.wikidata.org/wiki/Q1427245","display_name":"Stigma (botany)","level":2,"score":0.3142000138759613},{"id":"https://openalex.org/C2991880234","wikidata":"https://www.wikidata.org/wiki/Q23058086","display_name":"Global challenges","level":2,"score":0.3010999858379364},{"id":"https://openalex.org/C3019165603","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral treatment","level":5,"score":0.29339998960494995},{"id":"https://openalex.org/C2776452011","wikidata":"https://www.wikidata.org/wiki/Q311463","display_name":"Sida","level":4,"score":0.28679999709129333},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.26840001344680786},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.26170000433921814},{"id":"https://openalex.org/C3018553135","wikidata":"https://www.wikidata.org/wiki/Q67004728","display_name":"Medication adherence","level":2,"score":0.2603999972343445},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.2583000063896179},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.25429999828338623},{"id":"https://openalex.org/C3019451088","wikidata":"https://www.wikidata.org/wiki/Q67004728","display_name":"Patient compliance","level":2,"score":0.25}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057545","descriptor_name":"Social Stigma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058872","descriptor_name":"Epidemics","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D065129","descriptor_name":"Pre-Exposure Prophylaxis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/qad.0000000000003102","doi":"https://doi.org/10.1097/qad.0000000000003102","is_oa":true,"landing_page_url":"https://doi.org/10.1097/qad.0000000000003102","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},{"id":"pmid:34848580","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34848580","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS (London, England)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1097/qad.0000000000003102","doi":"https://doi.org/10.1097/qad.0000000000003102","is_oa":true,"landing_page_url":"https://doi.org/10.1097/qad.0000000000003102","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1968870951","https://openalex.org/W2002368050","https://openalex.org/W2005372538","https://openalex.org/W2056118601","https://openalex.org/W2164944270","https://openalex.org/W2404394069","https://openalex.org/W2559683026","https://openalex.org/W2600290565","https://openalex.org/W2606413115","https://openalex.org/W2628900802","https://openalex.org/W2737271551","https://openalex.org/W2739472324","https://openalex.org/W2778613387","https://openalex.org/W2782437520","https://openalex.org/W2782864025","https://openalex.org/W2783569476","https://openalex.org/W2802170264","https://openalex.org/W2803001373","https://openalex.org/W2803051518","https://openalex.org/W2803243584","https://openalex.org/W2804482078","https://openalex.org/W2805069146","https://openalex.org/W2899414149","https://openalex.org/W2899500909","https://openalex.org/W2931770039","https://openalex.org/W2945872312","https://openalex.org/W2953312173","https://openalex.org/W2957344220","https://openalex.org/W2963426746","https://openalex.org/W2973798064","https://openalex.org/W2976069364","https://openalex.org/W2977486383","https://openalex.org/W2982097452","https://openalex.org/W2995020465","https://openalex.org/W3000121819","https://openalex.org/W3009494891","https://openalex.org/W3009647661","https://openalex.org/W3010513804","https://openalex.org/W3018289581","https://openalex.org/W3024705890","https://openalex.org/W3027401261","https://openalex.org/W3031156276","https://openalex.org/W3035086772","https://openalex.org/W3036716176","https://openalex.org/W3043101786","https://openalex.org/W3045379633","https://openalex.org/W3082576563","https://openalex.org/W3086372976","https://openalex.org/W3111050887","https://openalex.org/W3126154687","https://openalex.org/W3136625448","https://openalex.org/W3138429504"],"related_works":["https://openalex.org/W4404523184","https://openalex.org/W4309660721","https://openalex.org/W618752614","https://openalex.org/W2898368813","https://openalex.org/W1984798383","https://openalex.org/W4224223743","https://openalex.org/W2404394069","https://openalex.org/W7155035835","https://openalex.org/W4306639125","https://openalex.org/W2081072651"],"abstract_inverted_index":{"Long-acting":[0,22],"antiretroviral":[1],"drugs":[2],"have":[3],"emerged":[4],"as":[5],"exciting":[6],"treatment":[7,48,78],"and":[8,17,29,49,54,64,74,77,102],"preexposure":[9],"prophylaxis":[10],"(PrEP)":[11],"options":[12,79],"for":[13,46,115],"people":[14],"with":[15,32,43],"HIV":[16,75],"at":[18],"risk":[19],"of":[20,86,112],"HIV.":[21],"regimens":[23],"may":[24],"improve":[25],"dosing":[26],"convenience,":[27],"tolerability":[28],"cost":[30],"compared":[31],"current":[33],"daily-based":[34],"oral":[35,44],"therapy.":[36],"They":[37],"can":[38],"also":[39],"circumvent":[40],"stigma":[41],"associated":[42],"therapy":[45],"both":[47],"PrEP,":[50],"thereby":[51],"improving":[52],"adherence":[53],"outcomes.":[55],"Yet,":[56],"multiple":[57],"challenges":[58,104],"remain,":[59],"many":[60],"specific":[61],"to":[62],"low-income":[63],"middle-income":[65],"countries":[66],"(LMICs),":[67],"where":[68],"the":[69,84,110],"epidemic":[70],"is":[71],"most":[72],"concentrated":[73],"prevention":[76],"are":[80,105],"limited.":[81],"To":[82],"optimize":[83],"use":[85],"long-acting":[87,113],"formulations,":[88],"key":[89],"outstanding":[90],"questions":[91],"must":[92],"be":[93],"addressed.":[94],"Uncertain":[95],"costing,":[96],"scale-up":[97],"manufacturing,":[98],"complex":[99],"delivery":[100],"systems":[101],"implementation":[103],"potential":[106],"barriers":[107],"when":[108],"considering":[109],"scalability":[111],"ARVs":[114],"global":[116],"use.":[117]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-11-08T00:00:00"}