{"id":"https://openalex.org/W3210186306","doi":"https://doi.org/10.1002/jcla.24039","title":"Longitudinal change in microRNA\u2010130a expression and its correlation with the risk of developing major adverse cardiovascular and cerebral events in patients undergoing continuous ambulatory peritoneal dialysis","display_name":"Longitudinal change in microRNA\u2010130a expression and its correlation with the risk of developing major adverse cardiovascular and cerebral events in patients undergoing continuous ambulatory peritoneal dialysis","publication_year":2021,"publication_date":"2021-10-28","ids":{"openalex":"https://openalex.org/W3210186306","doi":"https://doi.org/10.1002/jcla.24039","mag":"3210186306","pmid":"https://pubmed.ncbi.nlm.nih.gov/34708454","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8649386"},"language":"en","primary_location":{"id":"doi:10.1002/jcla.24039","doi":"https://doi.org/10.1002/jcla.24039","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jcla.24039","pdf_url":null,"source":{"id":"https://openalex.org/S28295008","display_name":"Journal of Clinical Laboratory Analysis","issn_l":"0887-8013","issn":["0887-8013","1098-2825"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Laboratory Analysis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1002/jcla.24039","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Hong Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143819","display_name":"Taizhou First People's Hospital","ror":"https://ror.org/04jyt7608","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143819"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Wang","raw_affiliation_strings":["Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China","institution_ids":["https://openalex.org/I4210143819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069747026","display_name":"Jinglin Xu","orcid":"https://orcid.org/0000-0002-1553-5441","observed_orcids":["https://orcid.org/0000-0002-1553-5441"]},"institutions":[{"id":"https://openalex.org/I4210143819","display_name":"Taizhou First People's Hospital","ror":"https://ror.org/04jyt7608","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143819"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinglin Xu","raw_affiliation_strings":["Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China","institution_ids":["https://openalex.org/I4210143819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085140100","display_name":"Xinhong Wu","orcid":"https://orcid.org/0000-0001-7185-6787","observed_orcids":["https://orcid.org/0000-0001-7185-6787"]},"institutions":[{"id":"https://openalex.org/I4210143819","display_name":"Taizhou First People's Hospital","ror":"https://ror.org/04jyt7608","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143819"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhong Wu","raw_affiliation_strings":["Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China","institution_ids":["https://openalex.org/I4210143819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069808406","display_name":"Shouhao Zheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143819","display_name":"Taizhou First People's Hospital","ror":"https://ror.org/04jyt7608","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143819"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shouhao Zheng","raw_affiliation_strings":["Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China","institution_ids":["https://openalex.org/I4210143819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072862524","display_name":"Yingmin Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143819","display_name":"Taizhou First People's Hospital","ror":"https://ror.org/04jyt7608","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143819"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingmin Han","raw_affiliation_strings":["Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China","institution_ids":["https://openalex.org/I4210143819"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006825997","display_name":"Ding Guo-ming","orcid":"https://orcid.org/0000-0001-9806-7868","observed_orcids":["https://orcid.org/0000-0001-9806-7868"]},"institutions":[{"id":"https://openalex.org/I4210143819","display_name":"Taizhou First People's Hospital","ror":"https://ror.org/04jyt7608","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143819"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guoming Ding","raw_affiliation_strings":["Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China"],"raw_orcid":"https://orcid.org/0000-0001-9806-7868","affiliations":[{"raw_affiliation_string":"Department of Nephrology Taizhou First People\u2019s Hospital Taizhou Zhejiang China","institution_ids":["https://openalex.org/I4210143819"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5006825997"],"corresponding_institution_ids":["https://openalex.org/I4210143819"],"apc_list":{"value":2200,"currency":"USD","value_usd":2200},"apc_paid":{"value":2200,"currency":"USD","value_usd":2200},"fwci":0.668,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.68135095,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"35","issue":"12","first_page":"e24039","last_page":"e24039"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.7045999765396118,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.7045999765396118,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.27730000019073486,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna-130a","display_name":"microRNA-130a","score":0.984000027179718},{"id":"https://openalex.org/keywords/continuous-ambulatory-peritoneal-dialysis","display_name":"continuous ambulatory peritoneal dialysis","score":0.9330000281333923},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.9869999885559082},{"id":"https://openalex.org/keywords/major-adverse-cardiac-and-cerebrovascular-events","display_name":"major adverse cardiac and cerebrovascular events","score":0.9909999966621399},{"id":"https://openalex.org/keywords/peripheral-blood-mononuclear-cells","display_name":"peripheral blood mononuclear cells","score":0.8920000195503235},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7879999876022339},{"id":"https://openalex.org/keywords/longitudinal-gene-expression","display_name":"longitudinal gene expression","score":0.7870000004768372},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C2909406889","wikidata":"https://www.wikidata.org/wiki/Q1756474","display_name":"Continuous ambulatory peritoneal dialysis","level":3,"score":0.7107931971549988},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6721415519714355},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5366280674934387},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.5018949508666992},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.4921106696128845},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.48862797021865845},{"id":"https://openalex.org/C2779056158","wikidata":"https://www.wikidata.org/wiki/Q1756474","display_name":"Peritoneal dialysis","level":2,"score":0.47822636365890503},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4326808452606201},{"id":"https://openalex.org/C3019040382","wikidata":"https://www.wikidata.org/wiki/Q476921","display_name":"End stage renal disease","level":3,"score":0.41784483194351196},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.41278302669525146},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.21938112378120422},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1320238709449768},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001927","descriptor_name":"Brain Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D001927","descriptor_name":"Brain Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010531","descriptor_name":"Peritoneal Dialysis, Continuous Ambulatory","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010531","descriptor_name":"Peritoneal Dialysis, Continuous Ambulatory","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/jcla.24039","doi":"https://doi.org/10.1002/jcla.24039","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jcla.24039","pdf_url":null,"source":{"id":"https://openalex.org/S28295008","display_name":"Journal of Clinical Laboratory Analysis","issn_l":"0887-8013","issn":["0887-8013","1098-2825"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Laboratory Analysis","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8649386","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8649386","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Lab Anal","raw_type":"Text"},{"id":"pmid:34708454","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34708454","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical laboratory analysis","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/jcla.24039","doi":"https://doi.org/10.1002/jcla.24039","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jcla.24039","pdf_url":null,"source":{"id":"https://openalex.org/S28295008","display_name":"Journal of Clinical Laboratory Analysis","issn_l":"0887-8013","issn":["0887-8013","1098-2825"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Laboratory Analysis","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W2099768740","https://openalex.org/W2195706369","https://openalex.org/W2529025963","https://openalex.org/W2575562298","https://openalex.org/W2775255518","https://openalex.org/W2791735321","https://openalex.org/W2808334162","https://openalex.org/W2901509160","https://openalex.org/W2901859262","https://openalex.org/W2921582523","https://openalex.org/W2952900316","https://openalex.org/W2965263775","https://openalex.org/W2968513998","https://openalex.org/W2980468600","https://openalex.org/W2990373393","https://openalex.org/W2995376303","https://openalex.org/W3007264226","https://openalex.org/W3008556076","https://openalex.org/W3025749607","https://openalex.org/W3035840352","https://openalex.org/W3044724336","https://openalex.org/W3048852187","https://openalex.org/W3089039155","https://openalex.org/W3090810033","https://openalex.org/W3096791720","https://openalex.org/W3138080509","https://openalex.org/W3138364899"],"related_works":["https://openalex.org/W2965263775","https://openalex.org/W3008556076","https://openalex.org/W3138364899","https://openalex.org/W4401380601","https://openalex.org/W4416768912","https://openalex.org/W4322492899","https://openalex.org/W2901509160","https://openalex.org/W7161271868","https://openalex.org/W2950469974","https://openalex.org/W3202976371"],"abstract_inverted_index":{"BACKGROUND:":[0],"MicroRNA-130a":[1],"(miR-130a)":[2],"regulates":[3],"angio-cellular":[4],"dysregulation,":[5],"atherosclerosis,":[6],"and":[7,18,80,91,117,163,188,206],"cardiocerebral":[8],"injuries,":[9],"serving":[10],"as":[11],"a":[12,46],"biomarker":[13],"for":[14,216],"major":[15],"adverse":[16],"cardiovascular":[17],"cerebral":[19],"events":[20],"(MACCE)":[21],"in":[22,30,67,128,134,149,168,173,197,239,254],"several":[23],"chronic":[24],"diseases.":[25],"However,":[26],"its":[27],"clinical":[28],"application":[29],"patients":[31,83,102,130,151,169,199,240],"with":[32,170,193,236,241,251],"end-stage":[33],"renal":[34],"disease":[35,237],"(ESRD)":[36],"undergoing":[37,84,103,131,152,200,243],"continuous":[38],"ambulatory":[39],"peritoneal":[40],"dialysis":[41],"(CAPD),":[42],"who":[43],"are":[44],"at":[45,78,86,160,185,210],"high":[47,182,207],"risk":[48,253],"of":[49],"developing":[50],"MACCE,":[51],"has":[52],"not":[53],"been":[54],"reported.":[55],"Therefore,":[56],"this":[57,62,246],"study":[58],"aimed":[59],"to":[60,147],"explore":[61],"aspect.":[63],"METHODS:":[64],"miR-130a":[65,123,141,158,183,208,232],"expression":[66,124,142,159,184,209,233,247],"peripheral":[68],"blood":[69],"mononuclear":[70],"cells":[71],"obtained":[72],"from":[73,145],"50":[74],"healthy":[75],"controls":[76],"(HCs)":[77],"recruitment":[79],"257":[81],"ESRD":[82,101,129,150,198,242],"CAPD":[85,104,132,153,201],"month":[87],"(M)0,":[88],"M12,":[89,162,187],"M24,":[90],"M36":[92,148,189],"was":[93,120,125,165,190,212],"determined":[94],"by":[95],"reverse":[96],"transcription-quantitative":[97],"polymerase":[98],"chain":[99],"reaction.":[100],"were":[105,115],"followed":[106],"up":[107],"until":[108],"MACCE":[109,114,171,176,252],"occurred":[110],"or":[111],"M36.":[112],"Then,":[113],"recorded,":[116],"MACCE-free":[118,195,218],"survival":[119,196,219],"calculated.":[121],"RESULTS:":[122],"significantly":[126,143,166,191],"lower":[127,167],"than":[133,172],"HCs":[135],"(p":[136,154,220],"<":[137,155,179,204],"0.001).":[138,156],"In":[139],"addition,":[140],"decreased":[144],"M0":[146,211],"Moreover,":[157],"M0,":[161,186],"M24":[164],"those":[174],"without":[175],"(all":[177,202],"p":[178,203],"0.05).":[180],"Furthermore,":[181],"correlated":[192,250],"prolonged":[194],"0.05),":[205],"an":[213],"independent":[214],"factor":[215],"improved":[217],"=":[221],"0.015;":[222],"hazard":[223],"ratio":[224],"(HR)":[225],"(95%":[226],"confidential":[227],"interval):":[228],"0.456":[229],"(0.243-0.857)).":[230],"CONCLUSION:":[231],"decreases":[234],"continuously":[235],"progression":[238],"CAPD.":[244],"Additionally,":[245],"is":[248],"negatively":[249],"these":[255],"patients.":[256]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-11-08T00:00:00"}