{"id":"https://openalex.org/W3210136835","doi":"https://doi.org/10.1155/2021/7612380","title":"Anti\u2010Inflammatory Activity and Chemical Analysis of Different Fractions from Solidago chilensis Inflorescence","display_name":"Anti\u2010Inflammatory Activity and Chemical Analysis of Different Fractions from Solidago chilensis Inflorescence","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3210136835","doi":"https://doi.org/10.1155/2021/7612380","mag":"3210136835","pmid":"https://pubmed.ncbi.nlm.nih.gov/34745422","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8570869"},"language":"en","primary_location":{"id":"doi:10.1155/2021/7612380","doi":"https://doi.org/10.1155/2021/7612380","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2021/7612380","pdf_url":"https://downloads.hindawi.com/journals/omcl/2021/7612380.pdf","source":{"id":"https://openalex.org/S20935308","display_name":"Oxidative Medicine and Cellular Longevity","issn_l":"1942-0994","issn":["1942-0994","1942-0900"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","medline","poland-20"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxidative Medicine and Cellular Longevity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/omcl/2021/7612380.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072942946","display_name":"Thais Morais de Brito","orcid":"https://orcid.org/0000-0002-6516-7245","observed_orcids":["https://orcid.org/0000-0002-6516-7245"]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Thais Morais de Brito","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-6516-7245","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069349873","display_name":"F\u00e1bio Coelho Amendoeira","orcid":"https://orcid.org/0000-0003-3573-5261","observed_orcids":["https://orcid.org/0000-0003-3573-5261"]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fabio Coelho Amendoeira","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-3573-5261","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053571918","display_name":"Temistocles Barroso de Oliveira","orcid":"https://orcid.org/0000-0003-1452-9012","observed_orcids":["https://orcid.org/0000-0003-1452-9012"]},"institutions":[{"id":"https://openalex.org/I4405287365","display_name":"Instituto de Tecnologia em F\u00e1rmacos","ror":"https://ror.org/04zshw128","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405287365","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Temistocles Barroso de Oliveira","raw_affiliation_strings":["Laborat\u00f3rio de Qu\u00edmica Medicinal de Produtos Bioativos, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Qu\u00edmica Medicinal de Produtos Bioativos, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405287365","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073349437","display_name":"La\u00eds Higino Doro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"La\u00eds Higino Doro","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074670140","display_name":"Esdras Barbosa Garcia","orcid":"https://orcid.org/0000-0002-0991-4218","observed_orcids":["https://orcid.org/0000-0002-0991-4218"]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Esdras Barbosa Garcia","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-0991-4218","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012762869","display_name":"Na\u00edna Monsores F\u00e9lix da Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Na\u00edna Monsores Felix da Silva","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016943104","display_name":"Amanda da Silva Chaves","orcid":"https://orcid.org/0000-0002-9997-0773","observed_orcids":["https://orcid.org/0000-0002-9997-0773"]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Amanda da Silva Chaves","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-9997-0773","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038072226","display_name":"Fl\u00e1via Fontenelle Muylaert","orcid":"https://orcid.org/0000-0001-8974-0918","observed_orcids":["https://orcid.org/0000-0001-8974-0918"]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Flavia Fontenelle Muylaert","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-8974-0918","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048473398","display_name":"Tatiana Almeida P\u00e1dua","orcid":"https://orcid.org/0000-0003-2505-9482","observed_orcids":["https://orcid.org/0000-0003-2505-9482"]},"institutions":[{"id":"https://openalex.org/I4405287365","display_name":"Instituto de Tecnologia em F\u00e1rmacos","ror":"https://ror.org/04zshw128","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405287365","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tatiana Almeida P\u00e1dua","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia Aplicada, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-2505-9482","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia Aplicada, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405287365","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086594704","display_name":"Elaine Cruz Rosas","orcid":"https://orcid.org/0000-0001-9612-0063","observed_orcids":["https://orcid.org/0000-0001-9612-0063"]},"institutions":[{"id":"https://openalex.org/I4405287365","display_name":"Instituto de Tecnologia em F\u00e1rmacos","ror":"https://ror.org/04zshw128","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405287365","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Elaine Cruz Rosas","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia Aplicada, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9612-0063","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia Aplicada, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405287365","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016036898","display_name":"Maria das Gra\u00e7as Henriques","orcid":"https://orcid.org/0000-0003-3065-0541","observed_orcids":["https://orcid.org/0000-0003-3065-0541"]},"institutions":[{"id":"https://openalex.org/I4405287365","display_name":"Instituto de Tecnologia em F\u00e1rmacos","ror":"https://ror.org/04zshw128","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405287365","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Maria das Gra\u00e7as M. O. Henriques","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia Aplicada, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-3065-0541","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia Aplicada, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405287365","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019481313","display_name":"V\u00e1lber da Silva Frutuoso","orcid":"https://orcid.org/0009-0009-6695-9808","observed_orcids":["https://orcid.org/0009-0009-6695-9808"]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Valber da Silva Frutuoso","raw_affiliation_strings":["Laborat\u00f3rio de Imunofarmacologia, Instituto Oswaldo Cruz-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Imunofarmacologia, Instituto Oswaldo Cruz-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012682904","display_name":"Simone Sacramento Valverde","orcid":"https://orcid.org/0000-0001-9043-3739","observed_orcids":["https://orcid.org/0000-0001-9043-3739"]},"institutions":[{"id":"https://openalex.org/I4405287365","display_name":"Instituto de Tecnologia em F\u00e1rmacos","ror":"https://ror.org/04zshw128","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405287365","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Simone Sacramento Valverde","raw_affiliation_strings":["Laborat\u00f3rio de Qu\u00edmica Medicinal de Produtos Bioativos, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9043-3739","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Qu\u00edmica Medicinal de Produtos Bioativos, Instituto de Tecnologia em F\u00e1rmacos-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405287365","https://openalex.org/I52325"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042854259","display_name":"Fausto Klabund Ferraris","orcid":"https://orcid.org/0000-0001-9434-3503","observed_orcids":["https://orcid.org/0000-0001-9434-3503"]},"institutions":[{"id":"https://openalex.org/I4405286541","display_name":"Instituto Nacional de Controle de Qualidade em Sa\u00fade","ror":"https://ror.org/02ew1yw87","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286541","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Fausto Klabund Ferraris","raw_affiliation_strings":["Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9434-3503","affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Farmacologia, Instituto Nacional de Controle de Qualidade em Sa\u00fade-FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5042854259"],"corresponding_institution_ids":["https://openalex.org/I4405286541","https://openalex.org/I52325"],"apc_list":{"value":2680,"currency":"USD","value_usd":2680},"apc_paid":{"value":2680,"currency":"USD","value_usd":2680},"fwci":0.4336,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.57342275,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"2021","issue":"1","first_page":"7612380","last_page":"7612380"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.6460000276565552,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.6460000276565552,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies","score":0.149399995803833,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0869000032544136,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/solidago-chilensis","display_name":"Solidago chilensis","score":1.0},{"id":"https://openalex.org/keywords/arnica","display_name":"Arnica","score":0.8360000252723694},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.8629999756813049},{"id":"https://openalex.org/keywords/inflorescence","display_name":"inflorescence","score":0.8949999809265137},{"id":"https://openalex.org/keywords/plant-extract-fractions","display_name":"plant fractions","score":0.578000009059906},{"id":"https://openalex.org/keywords/dichloromethane-fraction","display_name":"dichloromethane fraction","score":0.9100000262260437},{"id":"https://openalex.org/keywords/aqueous-fraction","display_name":"aqueous fraction","score":0.8600000143051147},{"id":"https://openalex.org/keywords/n-hexane-fraction","display_name":"n-hexane fraction","score":0.7379999756813049},{"id":"https://openalex.org/keywords/butanolic-fraction","display_name":"butanolic fraction","score":0.8489999771118164},{"id":"https://openalex.org/keywords/leukocyte-migration","display_name":"leukocyte migration","score":0.8309999704360962},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7289999723434448},{"id":"https://openalex.org/keywords/cyclooxygenase-2","display_name":"cyclooxygenase-2","score":0.9570000171661377},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.7170000076293945},{"id":"https://openalex.org/keywords/chemokines","display_name":"chemokines","score":0.9229999780654907},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.8399999737739563},{"id":"https://openalex.org/keywords/chlorogenic-acid","display_name":"chlorogenic acid","score":0.9800000190734863},{"id":"https://openalex.org/keywords/isoquercitrin","display_name":"isoquercitrin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/n-alkanes","display_name":"n-alkanes","score":0.9430000185966492},{"id":"https://openalex.org/keywords/phytochemistry","display_name":"phytochemistry","score":0.7770000100135803}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5694411993026733},{"id":"https://openalex.org/C178165689","wikidata":"https://www.wikidata.org/wiki/Q156428","display_name":"Inflorescence","level":2,"score":0.5202397108078003},{"id":"https://openalex.org/C134550120","wikidata":"https://www.wikidata.org/wiki/Q184208","display_name":"Rhizome","level":2,"score":0.5090627074241638},{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.4917590916156769},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4907189607620239},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.42873644828796387},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.34826862812042236},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31832849979400635},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3091379702091217},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09845316410064697},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D036624","descriptor_name":"Solidago","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056626","descriptor_name":"Inflorescence","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D064209","descriptor_name":"Phytochemicals","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D064209","descriptor_name":"Phytochemicals","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D064209","descriptor_name":"Phytochemicals","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1155/2021/7612380","doi":"https://doi.org/10.1155/2021/7612380","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2021/7612380","pdf_url":"https://downloads.hindawi.com/journals/omcl/2021/7612380.pdf","source":{"id":"https://openalex.org/S20935308","display_name":"Oxidative Medicine and Cellular Longevity","issn_l":"1942-0994","issn":["1942-0994","1942-0900"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","medline","poland-20"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxidative Medicine and Cellular Longevity","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:7460313","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8570869","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8570869","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8570869","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxid Med Cell Longev","raw_type":"Text"},{"id":"pmid:34745422","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34745422","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxidative medicine and cellular longevity","raw_type":"Journal Article"},{"id":"pmh:oai:arca.fiocruz.br:icict/61548","doi":null,"is_oa":true,"landing_page_url":"https://arca.fiocruz.br/handle/icict/61548","pdf_url":null,"source":{"id":"https://openalex.org/S7407055450","display_name":"Arca - Reposit\u00f3rio Institucional da Fiocruz","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:doaj.org/article:09d71b86892445d7ada1f75f10be5289","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/09d71b86892445d7ada1f75f10be5289","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2021/7612380","doi":"https://doi.org/10.1155/2021/7612380","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2021/7612380","pdf_url":"https://downloads.hindawi.com/journals/omcl/2021/7612380.pdf","source":{"id":"https://openalex.org/S20935308","display_name":"Oxidative Medicine and Cellular Longevity","issn_l":"1942-0994","issn":["1942-0994","1942-0900"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","medline","poland-20"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oxidative Medicine and Cellular Longevity","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G29316538","display_name":null,"funder_award_id":"(Code 001)","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G7405440852","display_name":null,"funder_award_id":"E26/111.304/2014","funder_id":"https://openalex.org/F4320322749","funder_display_name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro"}],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322749","display_name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","ror":"https://ror.org/03kk0s825"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3210136835.pdf","grobid_xml":"https://content.openalex.org/works/W3210136835.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W103701493","https://openalex.org/W1582389153","https://openalex.org/W1754450320","https://openalex.org/W1928606420","https://openalex.org/W1965209996","https://openalex.org/W1966080280","https://openalex.org/W1966722774","https://openalex.org/W1980980723","https://openalex.org/W1990578525","https://openalex.org/W1991214027","https://openalex.org/W2004067074","https://openalex.org/W2015023745","https://openalex.org/W2016409762","https://openalex.org/W2016738631","https://openalex.org/W2020043659","https://openalex.org/W2020618233","https://openalex.org/W2020825744","https://openalex.org/W2024911106","https://openalex.org/W2028135173","https://openalex.org/W2045650143","https://openalex.org/W2049241173","https://openalex.org/W2051420025","https://openalex.org/W2067562116","https://openalex.org/W2067670322","https://openalex.org/W2076822541","https://openalex.org/W2082489849","https://openalex.org/W2088373353","https://openalex.org/W2092038435","https://openalex.org/W2093551098","https://openalex.org/W2125515765","https://openalex.org/W2151539516","https://openalex.org/W2151826099","https://openalex.org/W2159913536","https://openalex.org/W2177654281","https://openalex.org/W2240302466","https://openalex.org/W2244273880","https://openalex.org/W2400878013","https://openalex.org/W2759241460","https://openalex.org/W2782368533","https://openalex.org/W2922645795","https://openalex.org/W3045323249","https://openalex.org/W3048760844","https://openalex.org/W3068272450","https://openalex.org/W3111769357","https://openalex.org/W3203511441","https://openalex.org/W4240211429"],"related_works":["https://openalex.org/W2973868591","https://openalex.org/W2004067074","https://openalex.org/W2020825744","https://openalex.org/W3111769357","https://openalex.org/W2160719012","https://openalex.org/W2016409762","https://openalex.org/W2943276655","https://openalex.org/W1973346641","https://openalex.org/W2059318280","https://openalex.org/W2624934080"],"abstract_inverted_index":{"Solidago":[0],"chilensis":[1,59],"Meyen":[2],"(Compositae)":[3],"is":[4,60,66],"a":[5,67,258],"species":[6],"native":[7],"to":[8,36,86,90,133,158,218,272,279],"South":[9],"America":[10],"(Brazil)":[11],"popularly":[12],"known":[13],"as":[14,156,172],"arnica.":[15],"In":[16,138,193,225],"Brazilian":[17],"popular":[18],"medicine,":[19],"inflorescences":[20,284],"and":[21,40,50,89,97,104,112,126,152,164,182,185,191,199,211,222,232,246,257,276],"rhizomes":[22],"of":[23,32,48,57,69,81,100,118,144,230,242,261,285],"this":[24],"plant":[25],"have":[26],"been":[27],"used":[28],"since":[29],"the":[30,33,38,46,54,63,82,92,101,105,116,150,175,200,213,235,249,255,270],"end":[31],"19th":[34],"century":[35],"replace":[37],"exogenous":[39],"hepatotoxic":[41],"Arnica":[42],"montana":[43],"L.":[44],"in":[45,62,95,98,179,254,265],"treatment":[47],"edema":[49],"inflammatory":[51,183],"pathologies.":[52],"Although":[53],"anti\u2010inflammatory":[55],"activity":[56],"S.":[58,119,286],"evidenced":[61],"literature,":[64],"there":[65],"lack":[68],"studies":[70],"with":[71,238],"enriched":[72],"fractions":[73,107,127,154,282],"or":[74],"compounds":[75],"isolated":[76,114],"from":[77,115,283],"it.":[78],"The":[79,121],"objective":[80],"current":[83],"study":[84,268],"was":[85,147,263,269],"characterize":[87],"phytochemically":[88,280],"evaluate":[91],"pharmacological":[93],"action":[94],"vivo":[96],"vitro":[99],"crude":[102,123],"extract":[103,124],"different":[106,136],"(hexane,":[108],"dichloromethane,":[109],"acetal,":[110],"butanolic,":[111],"aqueous)":[113],"inflorescence":[117,122],"chilensis.":[120,287],"(ScIE)":[125],"were":[128,167,248],"administered":[129],"by":[130],"intraperitoneal":[131],"route":[132],"mice":[134],"at":[135],"doses.":[137],"an":[139,203],"LPS\u2010induced":[140],"pleurisy":[141],"model,":[142],"inhibition":[143],"leukocyte":[145,180],"influx":[146],"observed":[148],"for":[149,169],"ScIE":[151,198],"all":[153],"tested,":[155],"compared":[157],"controls.":[159],"Dichloromethane":[160],"(ScDicF),":[161],"butanolic":[162],"(ScButF),":[163],"aqueous":[165],"(ScAquF)":[166],"selected":[168],"further":[170],"analysis":[171],"they":[173],"showed":[174,234],"best":[176],"inhibitory":[177,204],"effects":[178,275],"migration":[181],"cytokine":[184],"chemokine":[186],"production:":[187],"TNF\u2010\u03b1,":[188],"CXCL1/KC,":[189],"CXCL2/MIP\u20102,":[190],"CCL11/eotaxin\u20101.":[192],"LPS\u2010stimulated":[194],"J774A.1":[195],"cell":[196],"line,":[197],"ScDicF":[201,231],"exhibited":[202],"effect":[205],"on":[206],"nitric":[207],"oxide":[208],"(NO)":[209],"production":[210,221],"downmodulated":[212],"COX\u20102":[214,223],"expression;":[215],"ScAquF":[216,233],"failed":[217],"modulate":[219],"NO":[220],"expression.":[224],"phytochemical":[226],"analysis,":[227],"HPLC\u2010UV\u2010DAD":[228],"chromatograms":[229],"main":[236],"peaks":[237],"UV":[239],"spectrum":[240],"characteristics":[241],"flavonoids;":[243],"chlorogenic":[244],"acid":[245],"isoquercetin":[247],"most":[250],"present":[251],"phytochemicals":[252],"identified":[253],"ScAquF,":[256],"high":[259],"number":[260],"n\u2010alkanes":[262],"found":[264],"ScHexF.":[266],"Our":[267],"first":[271],"address":[273],"biological":[274],"correlate":[277],"them":[278],"characterized":[281]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-11-08T00:00:00"}