{"id":"https://openalex.org/W3210074036","doi":"https://doi.org/10.1016/j.htct.2021.10.218","title":"CARACTER\u00cdSTICAS CL\u00cdNICAS E LABORATORIAIS DE 24 PACIENTES PORTADORES DE MASTOCITOSE SIST\u00caMICA (MS): ESTUDO UNIC\u00caNTRICO","display_name":"CARACTER\u00cdSTICAS CL\u00cdNICAS E LABORATORIAIS DE 24 PACIENTES PORTADORES DE MASTOCITOSE SIST\u00caMICA (MS): ESTUDO UNIC\u00caNTRICO","publication_year":2021,"publication_date":"2021-10-01","ids":{"openalex":"https://openalex.org/W3210074036","doi":"https://doi.org/10.1016/j.htct.2021.10.218","mag":"3210074036"},"language":"pt","primary_location":{"id":"doi:10.1016/j.htct.2021.10.218","doi":"https://doi.org/10.1016/j.htct.2021.10.218","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2021.10.218","pdf_url":null,"source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1016/j.htct.2021.10.218","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002239340","display_name":"Luan Lima Marchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"LL Marchi","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091201129","display_name":"Luciana Nardinelli","orcid":"https://orcid.org/0000-0003-1594-0778","observed_orcids":["https://orcid.org/0000-0003-1594-0778"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"L Nardinelli","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110779653","display_name":"Lucas Bassolli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"L Bassoli","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050752361","display_name":"Mayara D\u2019Auria Jacomassi","orcid":"https://orcid.org/0000-0002-7006-9295","observed_orcids":["https://orcid.org/0000-0002-7006-9295"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"MD Jacomassi","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005737158","display_name":"EA Rosseto-Welter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"EA Rosseto-Welter","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007202804","display_name":"Vanderson Rocha","orcid":"https://orcid.org/0000-0003-0094-619X","observed_orcids":["https://orcid.org/0000-0003-0094-619X","https://orcid.org/0000-0003-3520-7530"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"V Rocha","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105939477","display_name":"EDRP Velloso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"EDRP Velloso","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brasil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14777462,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"43","issue":null,"first_page":"S127","last_page":"S128"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11909","display_name":"Histiocytic Disorders and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-mastocytosis","display_name":"systemic mastocytosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/kit-d816v-mutation","display_name":"KIT D816V mutation","score":0.8899999856948853},{"id":"https://openalex.org/keywords/serum-tryptase","display_name":"serum tryptase","score":0.9319999814033508},{"id":"https://openalex.org/keywords/mast-cell-infiltration","display_name":"mast cell infiltration","score":0.5070000290870667},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"bone marrow","score":0.7889999747276306},{"id":"https://openalex.org/keywords/mast-cell-mediators","display_name":"mast cell mediators","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.807087779045105},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.47027426958084106},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3781190812587738},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.33636361360549927}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.htct.2021.10.218","doi":"https://doi.org/10.1016/j.htct.2021.10.218","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2021.10.218","pdf_url":null,"source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:f8a4d9e8707c482a872d5e8abdb89db6","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f8a4d9e8707c482a872d5e8abdb89db6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S127-S128 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.htct.2021.10.218","doi":"https://doi.org/10.1016/j.htct.2021.10.218","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2021.10.218","pdf_url":null,"source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3207408007","https://openalex.org/W4403553966","https://openalex.org/W4306319646","https://openalex.org/W7223108463","https://openalex.org/W4403568882","https://openalex.org/W4403568799","https://openalex.org/W4403568500","https://openalex.org/W2310958921","https://openalex.org/W7100895978","https://openalex.org/W4415670574"],"abstract_inverted_index":{"Analisar":[0],"as":[1,75],"caracter\u00edsticas":[2,306,389],"cl\u00ednicas":[3,307,390],"e":[4,55,100,121,132,154,206,226,238,265,287,290,308,321,364,382,391,413,421],"laboratoriais":[5,309,392],"de":[6,9,16,24,37,45,49,88,115,148,160,167,195,210,247,295,305,334,360,403],"pacientes":[7,21,80,157,253,272,292,311],"portadores":[8],"mastocitose":[10],"sist\u00eamica":[11],"(MS).":[12],"Estudo":[13],"observacional":[14],"retrospectivo,":[15],"01/03/19":[17],"a":[18,250,279,352,365,370,383],"28/02/21,":[19],"incluiu":[20],"com":[22,81,102,208,254,262,312,351],"diagn\u00f3stico":[23,87,146,325],"MS":[25,313,327,394],"em":[26,197,212,284,293,418],"seguimento":[27],"no":[28,314,423],"ambulat\u00f3rio":[29],"da":[30,42,84,129,176,187,218,245,326,355,377,393],"hematologia":[31],"do":[32,57,95,138,140,174,337,385,410],"HC":[33],"FMUSP.":[34],"Realizada":[35],"an\u00e1lise":[36],"prontu\u00e1rios,":[38],"entrevistas":[39],"presenciais,":[40],"dosagem":[41],"triptase,":[43,361],"coleta":[44],"material":[46],"para":[47,74],"estudo":[48],"muta\u00e7\u00e3o":[50,188],"KITD816V":[51],"por":[52],"PCR":[53],"digital":[54],"aplica\u00e7\u00e3o":[56],"escore":[58,242,362],"Mastocytosis":[59],"Activity":[60],"Score":[61],"adaptado":[62],"(MASadp,":[63],"F":[64],"Siebenhaar":[65],"\u22c5":[66],"2018).":[67],"Foram":[68,77],"considerados":[69],"apenas":[70,222],"os":[71,358],"dados":[72],"v\u00e1lidos":[73],"an\u00e1lises.":[76],"encontrados":[78],"24":[79],"MS.":[82],"Mediana":[83],"idade":[85,366],"ao":[86,103],"45,4":[89],"anos":[90,150],"(13":[91],"\u2013":[92,152,170,183],"64),":[93],"70,8%":[94],"sexo":[96],"feminino,":[97],"87,5%":[98],"brancos":[99],"62,4%":[101],"menos":[104],"ensino":[105],"m\u00e9dio":[106],"completo.":[107],"Ao":[108],"diagn\u00f3stico,":[109,343],"sintomas":[110,118,143,340],"mais":[111,231,281],"relatados":[112],"foram:":[113,125,233],"les\u00f5es":[114],"pele":[116],"(87%),":[117],"al\u00e9rgicos":[119],"(65%)":[120],"diarreia":[122],"(43%),":[123],"gatilhos":[124],"fric\u00e7\u00e3o":[126],"(85%),":[127],"altera\u00e7\u00e3o":[128],"temperatura":[130],"(70%)":[131],"\u00e1gua":[133],"quente":[134],"(65%).":[135],"A":[136,172,185,401],"mediana":[137,166,173,333],"tempo":[139],"in\u00edcio":[141,338],"dos":[142,156,203,252,302,310,339,379],"at\u00e9":[144,341],"o":[145,269,276,324,342],"foi":[147,179,190,220,260,278],"10":[149],"(3":[151],"30)":[153],"41,2%":[155],"apresentaram":[158,367],"epis\u00f3dio":[159],"anafilaxia":[161],"pr\u00e9vio.":[162],"O":[163,241,297],"MASadp":[164],"teve":[165],"8":[168,271],"(0":[169],"27).":[171],"valor":[175],"triptase":[177],"s\u00e9rica":[178],"59,7":[180],"ng/mL":[181],"(16,7":[182],"228).":[184],"pesquisa":[186],"D816V":[189],"positiva":[191],"(89%).":[192],"Infiltrados":[193],"densos":[194],"mast\u00f3citos":[196,204,211],"medula":[198],"\u00f3ssea":[199],"(61%),":[200],"imunofen\u00f3tipo":[201],"an\u00f4malo":[202],"(70,4%)":[205],"mielograma":[207],"presen\u00e7a":[209],"(38%).":[213],"Em":[214,349,373],"rela\u00e7\u00e3o":[215],"\u00e0":[216],"classifica\u00e7\u00e3o":[217],"OMS,":[219],"evidenciado":[221],"subtipo":[223],"indolente":[224],"(62,5%)":[225],"agressivo":[227],"(37,5%).":[228],"Os":[229],"sistemas":[230],"acometidos":[232],"tegumentar":[234],"(91,7%),":[235],"hematopoi\u00e9tico":[236],"(87,5%)":[237],"esquel\u00e9tico":[239],"(50%).":[240],"progn\u00f3stico":[243,363],"cl\u00ednico":[244,412,425],"cl\u00ednica":[246,356],"Mayo":[248],"demonstrou":[249],"predomin\u00e2ncia":[251,384],"baixo":[255],"risco":[256],"(64%).":[257],"Tratamento":[258],"sintom\u00e1tico":[259],"realizado":[261],"anti-histam\u00ednicos":[263],"(95.8%)":[264],"antileucotrienos":[266],"(20,8%).":[267],"Durante":[268],"acompanhamento":[270],"fizeram":[273],"tratamento":[274,285],"citoredutor,":[275],"interferon":[277],"medica\u00e7\u00e3o":[280],"utilizada":[282],"(2":[283],"ativo":[286],"4":[288],"pr\u00e9vios)":[289],"dois":[291],"uso":[294],"midostaurin.":[296],"presente":[298],"trabalho":[299],"fez":[300],"um":[301],"raros":[303],"levantamentos":[304],"Brasil.":[315],"Por":[316],"ser":[317],"uma":[318],"doen\u00e7a":[319,416],"rara":[320,417],"pouco":[322],"difundida,":[323],"ainda":[328,398],"\u00e9":[329],"feito":[330],"tardiamente,":[331],"evidenciando":[332],"120":[335],"meses":[336],"resultado":[344],"similar":[345,369],"encontrado":[346],"na":[347,395,408],"literatura.":[348],"semelhan\u00e7a":[350],"corte":[353],"hist\u00f3ria":[354],"Mayo,":[357],"valores":[359],"distribui\u00e7\u00e3o":[368,378],"nossa":[371,419],"casu\u00edstica.":[372],"contraste,":[374],"houve":[375],"diferen\u00e7a":[376],"subtipos":[380],"cl\u00ednicos":[381],"g\u00eanero":[386],"feminino.":[387],"As":[388],"popula\u00e7\u00e3o":[396,420],"brasileira":[397],"permanecem":[399],"desconhecidas.":[400],"realiza\u00e7\u00e3o":[402],"registro":[404],"nacional":[405],"pode":[406],"auxiliar":[407,422],"compreens\u00e3o":[409],"comportamento":[411],"laboratorial":[414],"desta":[415],"manejo":[424],"desses":[426],"pacientes.":[427]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2021-11-08T00:00:00"}