{"id":"https://openalex.org/W3209789787","doi":"https://doi.org/10.1016/j.healun.2021.10.010","title":"Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin","display_name":"Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin","publication_year":2021,"publication_date":"2021-10-25","ids":{"openalex":"https://openalex.org/W3209789787","doi":"https://doi.org/10.1016/j.healun.2021.10.010","mag":"3209789787","pmid":"https://pubmed.ncbi.nlm.nih.gov/34802874"},"language":"en","primary_location":{"id":"doi:10.1016/j.healun.2021.10.010","doi":"https://doi.org/10.1016/j.healun.2021.10.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.healun.2021.10.010","pdf_url":null,"source":{"id":"https://openalex.org/S42270594","display_name":"The Journal of Heart and Lung Transplantation","issn_l":"1053-2498","issn":["1053-2498","1557-3117"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Heart and Lung Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://researchprofiles.ku.dk/da/publications/c89f59ec-eb27-4fad-a2c1-a48d0413b004","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072944272","display_name":"Rafaela Vanin Pinto Ribeiro","orcid":"https://orcid.org/0000-0002-5627-9157","observed_orcids":["https://orcid.org/0000-0002-5627-9157"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Rafaela V.P. Ribeiro","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":"https://orcid.org/0000-0002-5627-9157","affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029664874","display_name":"Terrance Ku","orcid":"https://orcid.org/0000-0002-6757-3757","observed_orcids":["https://orcid.org/0000-0002-6757-3757"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Terrance Ku","raw_affiliation_strings":["Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023789637","display_name":"Aizhou Wang","orcid":"https://orcid.org/0000-0002-4684-9929","observed_orcids":["https://orcid.org/0000-0002-4684-9929"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Aizhou Wang","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":"https://orcid.org/0000-0002-4684-9929","affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087449793","display_name":"Layla Pires","orcid":"https://orcid.org/0000-0003-4558-5199","observed_orcids":["https://orcid.org/0000-0003-4558-5199"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Layla Pires","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020455985","display_name":"Victor H. Ferreira","orcid":"https://orcid.org/0000-0002-1472-9711","observed_orcids":["https://orcid.org/0000-0002-1472-9711"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Victor H. Ferreira","raw_affiliation_strings":["Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":"https://orcid.org/0000-0002-1472-9711","affiliations":[{"raw_affiliation_string":"Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028756480","display_name":"Vinicius Schenk Michaelsen","orcid":"https://orcid.org/0000-0001-9969-6033","observed_orcids":["https://orcid.org/0000-0001-9969-6033"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Vinicius Michaelsen","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078684130","display_name":"Aadil Ali","orcid":"https://orcid.org/0000-0002-9497-8290","observed_orcids":["https://orcid.org/0000-0002-9497-8290"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Aadil Ali","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051893182","display_name":"Marcos Galasso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marcos Galasso","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065739010","display_name":"Sajad Moshkelgosha","orcid":"https://orcid.org/0000-0002-7892-388X","observed_orcids":["https://orcid.org/0000-0002-7892-388X"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sajad Moshkelgosha","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066265292","display_name":"Anajara Gazzalle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Anajara Gazzalle","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057973675","display_name":"Mads Gravers Jeppesen","orcid":"https://orcid.org/0009-0001-9440-8247","observed_orcids":["https://orcid.org/0009-0001-9440-8247"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mads G. Jeppesen","raw_affiliation_strings":["Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035872776","display_name":"METTE MARIE ROSENKILDE","orcid":"https://orcid.org/0000-0001-9600-3254","observed_orcids":["https://orcid.org/0000-0001-9600-3254"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Mette M. Rosenkilde","raw_affiliation_strings":["Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark; Laboratory of Molecular Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","Laboratory of Molecular Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark; Laboratory of Molecular Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Laboratory of Molecular Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100709242","display_name":"Mingyao Liu","orcid":"https://orcid.org/0000-0002-9188-8417","observed_orcids":["https://orcid.org/0000-0002-9188-8417"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mingyao Liu","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":"https://orcid.org/0000-0002-9188-8417","affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033864764","display_name":"Lianne Gail Singer","orcid":"https://orcid.org/0000-0002-2693-8676","observed_orcids":["https://orcid.org/0000-0002-2693-8676"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Lianne G. Singer","raw_affiliation_strings":["Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":"https://orcid.org/0000-0002-2693-8676","affiliations":[{"raw_affiliation_string":"Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057779932","display_name":"Deepali Kumar","orcid":"https://orcid.org/0000-0003-1961-0477","observed_orcids":["https://orcid.org/0000-0003-1961-0477"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Deepali Kumar","raw_affiliation_strings":["Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":"https://orcid.org/0000-0003-1961-0477","affiliations":[{"raw_affiliation_string":"Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086297813","display_name":"Shaf H Keshavjee","orcid":"https://orcid.org/0000-0003-4547-8094","observed_orcids":["https://orcid.org/0000-0003-4547-8094"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Shaf Keshavjee","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]},{"raw_affiliation_string":"Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441"]},{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012950769","display_name":"John H. Sinclair","orcid":"https://orcid.org/0000-0002-2616-9571","observed_orcids":["https://orcid.org/0000-0002-2616-9571"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210156194","display_name":"Addenbrooke's Hospital","ror":"https://ror.org/055vbxf86","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802466933","https://openalex.org/I4210156194"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Sinclair","raw_affiliation_strings":["Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210156194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071806328","display_name":"Thomas Nitschke Kledal","orcid":"https://orcid.org/0000-0002-6320-4452","observed_orcids":["https://orcid.org/0000-0002-6320-4452"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas N. Kledal","raw_affiliation_strings":["Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Synklino ApS, Ole M\u00e5l\u00f8es vej X, Copenhagen, Denmark","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011382706","display_name":"Atul Humar","orcid":"https://orcid.org/0000-0002-1751-7159","observed_orcids":["https://orcid.org/0000-0002-1751-7159"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Atul Humar","raw_affiliation_strings":["Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091225330","display_name":"Marcelo Cypel","orcid":"https://orcid.org/0000-0001-5652-1938","observed_orcids":["https://orcid.org/0000-0001-5652-1938"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I4388446367","display_name":"Toronto General Hospital Research Institute","ror":"https://ror.org/04cm2y595","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744","https://openalex.org/I4388446367"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Marcelo Cypel","raw_affiliation_strings":["Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada. Electronic address: marcelo.cypel@uhn.ca","Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":"https://orcid.org/0000-0001-5652-1938","affiliations":[{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada. Electronic address: marcelo.cypel@uhn.ca","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]},{"raw_affiliation_string":"Ajmera Transplant Centre, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441"]},{"raw_affiliation_string":"Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5091225330"],"corresponding_institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I4388446367"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":3.8259,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.9445323,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"41","issue":"3","first_page":"287","last_page":"297"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.9243000149726868,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.9243000149726868,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.06300000101327896,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-cytomegalovirus","display_name":"human cytomegalovirus","score":0.9380000233650208},{"id":"https://openalex.org/keywords/latent-viral-reservoir","display_name":"latent viral reservoir","score":0.7910000085830688},{"id":"https://openalex.org/keywords/ex-vivo-lung-perfusion","display_name":"ex vivo lung perfusion","score":0.8420000076293945},{"id":"https://openalex.org/keywords/lung-transplantation","display_name":"lung transplantation","score":0.5730000138282776},{"id":"https://openalex.org/keywords/post-transplant-viral-reactivation","display_name":"post-transplant viral reactivation","score":0.9169999957084656},{"id":"https://openalex.org/keywords/cd14-monocytes","display_name":"CD14+ monocytes","score":0.8989999890327454},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C115085202","wikidata":"https://www.wikidata.org/wiki/Q425665","display_name":"Immunotoxin","level":4,"score":0.8629663586616516},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.719917356967926},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.5528638958930969},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5275368690490723},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.49670106172561646},{"id":"https://openalex.org/C2777732132","wikidata":"https://www.wikidata.org/wiki/Q6946","display_name":"Cytomegalovirus","level":5,"score":0.49476760625839233},{"id":"https://openalex.org/C2779820661","wikidata":"https://www.wikidata.org/wiki/Q6929","display_name":"Human cytomegalovirus","level":3,"score":0.48149216175079346},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4304051995277405},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40438270568847656},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.40191954374313354},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2395961582660675},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.15484467148780823},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.15261122584342957},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.10520404577255249},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.09375384449958801},{"id":"https://openalex.org/C2776409557","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Herpesviridae","level":4,"score":0.07554745674133301},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.0748119056224823},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.060788124799728394}],"mesh":[{"descriptor_ui":"D000922","descriptor_name":"Immunotoxins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000922","descriptor_name":"Immunotoxins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003586","descriptor_name":"Cytomegalovirus Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003587","descriptor_name":"Cytomegalovirus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005098","descriptor_name":"Exotoxins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016040","descriptor_name":"Lung Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018579","descriptor_name":"Patient Selection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.healun.2021.10.010","doi":"https://doi.org/10.1016/j.healun.2021.10.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.healun.2021.10.010","pdf_url":null,"source":{"id":"https://openalex.org/S42270594","display_name":"The Journal of Heart and Lung Transplantation","issn_l":"1053-2498","issn":["1053-2498","1557-3117"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Heart and Lung Transplantation","raw_type":"journal-article"},{"id":"pmid:34802874","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34802874","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire/c89f59ec-eb27-4fad-a2c1-a48d0413b004","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/c89f59ec-eb27-4fad-a2c1-a48d0413b004","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ribeiro, R V P, Ku, T, Wang, A, Pires, L, Ferreira, V H, Michaelsen, V, Ali, A, Galasso, M, Moshkelgosha, S, Gazzalle, A, Jeppesen, M G, Rosenkilde, M M, Liu, M, Singer, L G, Kumar, D, Keshavjee, S, Sinclair, J, Kledal, T N, Humar, A & Cypel, M 2022, 'Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin', Journal of Heart and Lung Transplantation, vol. 41, no. 3, pp. 287-297. https://doi.org/10.1016/j.healun.2021.10.010","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pure.atira.dk:openaire/c89f59ec-eb27-4fad-a2c1-a48d0413b004","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/c89f59ec-eb27-4fad-a2c1-a48d0413b004","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ribeiro, R V P, Ku, T, Wang, A, Pires, L, Ferreira, V H, Michaelsen, V, Ali, A, Galasso, M, Moshkelgosha, S, Gazzalle, A, Jeppesen, M G, Rosenkilde, M M, Liu, M, Singer, L G, Kumar, D, Keshavjee, S, Sinclair, J, Kledal, T N, Humar, A & Cypel, M 2022, 'Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin', Journal of Heart and Lung Transplantation, vol. 41, no. 3, pp. 287-297. https://doi.org/10.1016/j.healun.2021.10.010","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1933829943","display_name":null,"funder_award_id":"NNF19OC0055890","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G2063129663","display_name":"Understanding human cytomegalovirus latency as a means to target the latent reservoir","funder_award_id":"MR/S00081X/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G3649393898","display_name":null,"funder_award_id":"17181269","funder_id":"https://openalex.org/F4320313552","funder_display_name":"Toronto General and Western Hospital Foundation"},{"id":"https://openalex.org/G4363899365","display_name":null,"funder_award_id":"MR/K021087","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5225206887","display_name":null,"funder_award_id":"NNF18SA0034740","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G6885883952","display_name":"Human cytomegalovirus: changes in the latently infected cell as chemotherapeutic and immunological targets for antiviral therapy","funder_award_id":"MR/K021087/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7639727657","display_name":null,"funder_award_id":"NNF18SA0034740","funder_id":"https://openalex.org/F4320310308","funder_display_name":"Minneapolis Medical Research Foundation"}],"funders":[{"id":"https://openalex.org/F4320310308","display_name":"Minneapolis Medical Research Foundation","ror":"https://ror.org/01k7a6660"},{"id":"https://openalex.org/F4320313552","display_name":"Toronto General and Western Hospital Foundation","ror":"https://ror.org/00tfsm290"},{"id":"https://openalex.org/F4320325957","display_name":"Novo Nordisk Fonden","ror":"https://ror.org/04txyc737"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1482073722","https://openalex.org/W1505065427","https://openalex.org/W1529537962","https://openalex.org/W1536477464","https://openalex.org/W1963943606","https://openalex.org/W2001926968","https://openalex.org/W2008349036","https://openalex.org/W2032612463","https://openalex.org/W2036606193","https://openalex.org/W2042403790","https://openalex.org/W2081120686","https://openalex.org/W2082966150","https://openalex.org/W2083067632","https://openalex.org/W2111746719","https://openalex.org/W2114635506","https://openalex.org/W2121465576","https://openalex.org/W2121518761","https://openalex.org/W2122445103","https://openalex.org/W2127894722","https://openalex.org/W2135890826","https://openalex.org/W2142010179","https://openalex.org/W2150813780","https://openalex.org/W2167527394","https://openalex.org/W2223594321","https://openalex.org/W2553215107","https://openalex.org/W2584640377","https://openalex.org/W2774889729","https://openalex.org/W2888184647","https://openalex.org/W2888246207","https://openalex.org/W2911460858","https://openalex.org/W2913603052","https://openalex.org/W2920257015","https://openalex.org/W2923875868","https://openalex.org/W2969331232","https://openalex.org/W2972892084","https://openalex.org/W2980056121","https://openalex.org/W3084460949","https://openalex.org/W4293380371","https://openalex.org/W6746779121"],"related_works":["https://openalex.org/W7133058831","https://openalex.org/W3137019843","https://openalex.org/W3014229815","https://openalex.org/W4200445413","https://openalex.org/W6906569196","https://openalex.org/W7128695751","https://openalex.org/W7165405606","https://openalex.org/W2011852896","https://openalex.org/W2412661461","https://openalex.org/W4224252023"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-11-08T00:00:00"}