{"id":"https://openalex.org/W3209625812","doi":"https://doi.org/10.1111/jcpt.13553","title":"Impact of pharmacist intervention in antibiotic stewardship programmes for critically ill neonates: A systematic review and meta\u2010analysis","display_name":"Impact of pharmacist intervention in antibiotic stewardship programmes for critically ill neonates: A systematic review and meta\u2010analysis","publication_year":2021,"publication_date":"2021-10-30","ids":{"openalex":"https://openalex.org/W3209625812","doi":"https://doi.org/10.1111/jcpt.13553","mag":"3209625812","pmid":"https://pubmed.ncbi.nlm.nih.gov/34716722"},"language":"en","primary_location":{"id":"doi:10.1111/jcpt.13553","doi":"https://doi.org/10.1111/jcpt.13553","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jcpt.13553","pdf_url":null,"source":{"id":"https://openalex.org/S156693432","display_name":"Journal of Clinical Pharmacy and Therapeutics","issn_l":"0269-4727","issn":["0269-4727","1365-2710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Pharmacy and Therapeutics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100610701","display_name":"So Yeon Lee","orcid":"https://orcid.org/0000-0002-0109-0998","observed_orcids":["https://orcid.org/0000-0002-0109-0998"]},"institutions":[{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"So Yeon Lee","raw_affiliation_strings":["College of Pharmacy, Wonkwang University, Iksan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Wonkwang University, Iksan, Korea","institution_ids":["https://openalex.org/I77079311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055025410","display_name":"Sook Hee An","orcid":"https://orcid.org/0000-0002-7552-0233","observed_orcids":["https://orcid.org/0000-0002-7552-0233"]},"institutions":[{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Sook Hee An","raw_affiliation_strings":["College of Pharmacy, Wonkwang University, Iksan, Korea"],"raw_orcid":"https://orcid.org/0000-0002-7552-0233","affiliations":[{"raw_affiliation_string":"College of Pharmacy, Wonkwang University, Iksan, Korea","institution_ids":["https://openalex.org/I77079311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055025410"],"corresponding_institution_ids":["https://openalex.org/I77079311"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":0.2839,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.33075207,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"47","issue":"4","first_page":"430","last_page":"444"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13970","display_name":"Pharmacy and Medical Practices","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacist-intervention","display_name":"pharmacist intervention","score":0.8619999885559082},{"id":"https://openalex.org/keywords/critically-ill-neonates","display_name":"critically ill neonates","score":0.9950000047683716},{"id":"https://openalex.org/keywords/antibiotic-use-reduction","display_name":"antibiotic use reduction","score":0.906000018119812},{"id":"https://openalex.org/keywords/antibiotic-duration","display_name":"antibiotic duration","score":0.9200000166893005},{"id":"https://openalex.org/keywords/role-of-pharmacists","display_name":"pharmacist role","score":0.6029999852180481},{"id":"https://openalex.org/keywords/neonatal-intensive-care","display_name":"neonatal intensive care","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.7927968502044678},{"id":"https://openalex.org/C2911146124","wikidata":"https://www.wikidata.org/wiki/Q19903321","display_name":"Antibiotic Stewardship","level":4,"score":0.7603937387466431},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6770135164260864},{"id":"https://openalex.org/C2779457091","wikidata":"https://www.wikidata.org/wiki/Q105186","display_name":"Pharmacist","level":3,"score":0.6746617555618286},{"id":"https://openalex.org/C2777950569","wikidata":"https://www.wikidata.org/wiki/Q17021836","display_name":"Stewardship (theology)","level":3,"score":0.631817102432251},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6210470199584961},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5605693459510803},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.5093542337417603},{"id":"https://openalex.org/C2776040555","wikidata":"https://www.wikidata.org/wiki/Q19903321","display_name":"Antimicrobial stewardship","level":4,"score":0.48631224036216736},{"id":"https://openalex.org/C10446079","wikidata":"https://www.wikidata.org/wiki/Q155491","display_name":"Clinical pharmacy","level":3,"score":0.45756155252456665},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.384845107793808},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.2854970097541809},{"id":"https://openalex.org/C104863432","wikidata":"https://www.wikidata.org/wiki/Q614304","display_name":"Pharmacy","level":2,"score":0.19654110074043274},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09124445915222168},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.06693652272224426},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.06441852450370789},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000073602","descriptor_name":"Antimicrobial Stewardship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006761","descriptor_name":"Hospitals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010595","descriptor_name":"Pharmacists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/jcpt.13553","doi":"https://doi.org/10.1111/jcpt.13553","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jcpt.13553","pdf_url":null,"source":{"id":"https://openalex.org/S156693432","display_name":"Journal of Clinical Pharmacy and Therapeutics","issn_l":"0269-4727","issn":["0269-4727","1365-2710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Pharmacy and Therapeutics","raw_type":"journal-article"},{"id":"pmid:34716722","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34716722","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical pharmacy and therapeutics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[{"id":"https://openalex.org/G1939659454","display_name":null,"funder_award_id":"NRF\u20102019R1F1A1058891","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"}],"funders":[{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1534181333","https://openalex.org/W1910023637","https://openalex.org/W1983484996","https://openalex.org/W2014411687","https://openalex.org/W2029532220","https://openalex.org/W2083273981","https://openalex.org/W2099120597","https://openalex.org/W2125435699","https://openalex.org/W2134911498","https://openalex.org/W2168908910","https://openalex.org/W2170892587","https://openalex.org/W2221677728","https://openalex.org/W2324765444","https://openalex.org/W2411591633","https://openalex.org/W2464048734","https://openalex.org/W2467068951","https://openalex.org/W2529117920","https://openalex.org/W2535661077","https://openalex.org/W2624048723","https://openalex.org/W2731694262","https://openalex.org/W2737773580","https://openalex.org/W2767199226","https://openalex.org/W2781639197","https://openalex.org/W2790674600","https://openalex.org/W2794907715","https://openalex.org/W2795144068","https://openalex.org/W2801710611","https://openalex.org/W2803133202","https://openalex.org/W2807361721","https://openalex.org/W2910222792","https://openalex.org/W2920116900","https://openalex.org/W2921547160","https://openalex.org/W2932169095","https://openalex.org/W2943736196","https://openalex.org/W2944458253","https://openalex.org/W2946209372","https://openalex.org/W2948981524","https://openalex.org/W2972092187","https://openalex.org/W2990093987","https://openalex.org/W2997760383","https://openalex.org/W2998478075","https://openalex.org/W3014128024","https://openalex.org/W3014860680","https://openalex.org/W3036580859","https://openalex.org/W3038716488","https://openalex.org/W3093292542","https://openalex.org/W3111312767","https://openalex.org/W3118206754","https://openalex.org/W3118615836","https://openalex.org/W3155874372","https://openalex.org/W4252147621"],"related_works":["https://openalex.org/W4391339034","https://openalex.org/W2911458832","https://openalex.org/W4401033601","https://openalex.org/W3012534465","https://openalex.org/W4389486701","https://openalex.org/W4408845384","https://openalex.org/W3155277634","https://openalex.org/W4293510180","https://openalex.org/W4414419270","https://openalex.org/W4400110833"],"abstract_inverted_index":{"WHAT":[0,238],"IS":[1,239],"KNOWN":[2],"AND":[3,126,241],"OBJECTIVE:":[4],"Antibiotic":[5],"stewardship":[6],"programmes":[7],"(ASPs)":[8],"are":[9],"introduced":[10],"to":[11,22,140],"ensure":[12],"effective":[13],"antibiotic":[14,26,64,153,157,177,199,218,263],"use.":[15,27,65,178],"Pharmacists":[16,137],"can":[17],"be":[18],"involved":[19],"in":[20,35,51,53,90,104,134,144,149,160,185,196,250,271,273],"ASPs":[21,52,91,246,272],"facilitate":[23],"the":[24,58,86,97,119,150,197,214,257],"appropriate":[25],"Prolonged":[28],"use":[29,154,200,259],"of":[30,60,70,88,99,152,203,217,228,245,262],"antibiotics":[31],"causes":[32],"adverse":[33],"events":[34],"critically":[36,54,93,186,251,274],"ill":[37,55,94,187,252,275],"neonates.":[38,276],"Hence,":[39],"this":[40,105,135],"systematic":[41],"review":[42],"and":[43,57,73,82,96,115,175,260],"meta-analysis":[44,180],"was":[45,80,121,189,254],"aimed":[46],"at":[47],"investigating":[48],"pharmacists'":[49],"functions":[50,87,143],"neonates":[56,95,188],"effect":[59],"ASP":[61,100,166,183,225],"implementation":[62,101,184,226,244],"on":[63],"METHODS:":[66],"A":[67,179],"comprehensive":[68],"search":[69],"PubMed/Medline,":[71],"Embase,":[72],"Cochrane":[74],"Library":[75],"databases":[76],"until":[77],"January":[78],"2021":[79],"conducted":[81],"studies":[83,131],"that":[84,182],"reported":[85],"pharmacists":[89,266],"for":[92],"results":[98],"were":[102,109,132,138],"included":[103,133],"review.":[106,136],"All":[107],"processes":[108],"performed":[110],"by":[111,123,222],"two":[112,120],"reviewers":[113],"independently,":[114],"any":[116],"discordance":[117],"between":[118],"resolved":[122],"discussion.":[124],"RESULTS":[125],"DISCUSSION:":[127],"In":[128],"all,":[129],"19":[130],"found":[139],"have":[141],"various":[142],"ASPs,":[145],"such":[146],"as":[147],"participating":[148,159],"development":[151],"guidelines,":[155],"auditing":[156],"prescriptions,":[158],"multidisciplinary":[161],"ward":[162],"rounds,":[163],"educating":[164],"other":[165],"team":[167],"members,":[168],"checking":[169],"blood":[170],"culture":[171],"or":[172],"laboratory":[173],"data,":[174],"monitoring":[176],"revealed":[181],"significantly":[190,220],"associated":[191,255],"with":[192,224,256],"a":[193,268],"23%":[194],"reduction":[195],"overall":[198,215],"rate":[201],"(ratio":[202,227],"means:":[204,229],"0.77,":[205],"95%":[206,231],"confidence":[207,232],"interval:":[208,233],"0.69-0.87,":[209],"p":[210,235],"<":[211,236],"0.001).":[212,237],"Moreover,":[213],"duration":[216,261],"therapy":[219],"reduced":[221,258],"15%":[223],"0.85,":[230],"0.78-0.91,":[234],"NEW":[240],"CONCLUSION:":[242],"The":[243],"involving":[247],"pharmacists,":[248],"especially":[249],"neonates,":[253],"treatment.":[264],"Thus,":[265],"played":[267],"key":[269],"role":[270]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-11-08T00:00:00"}