{"id":"https://openalex.org/W3209562872","doi":"https://doi.org/10.1177/22925503211042863","title":"Burn Center Patients at Risk for Upper Extremity Amputations","display_name":"Burn Center Patients at Risk for Upper Extremity Amputations","publication_year":2021,"publication_date":"2021-10-20","ids":{"openalex":"https://openalex.org/W3209562872","doi":"https://doi.org/10.1177/22925503211042863","mag":"3209562872","pmid":"https://pubmed.ncbi.nlm.nih.gov/37654535","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10467439"},"language":"en","primary_location":{"id":"doi:10.1177/22925503211042863","doi":"https://doi.org/10.1177/22925503211042863","is_oa":false,"landing_page_url":"https://doi.org/10.1177/22925503211042863","pdf_url":null,"source":{"id":"https://openalex.org/S4210203465","display_name":"Plastic Surgery","issn_l":"1195-2199","issn":["1195-2199","1918-1507","2292-5503","2292-5511"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10467439/pdf/10.1177_22925503211042863.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067198824","display_name":"Danielle A. Thornburg","orcid":"https://orcid.org/0000-0002-7822-9425","observed_orcids":["https://orcid.org/0000-0002-7822-9425"]},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Danielle A. Thornburg","raw_affiliation_strings":["Mayo Clinic Arizona, Phoenix, AZ, USA"],"raw_orcid":"https://orcid.org/0000-0002-7822-9425","affiliations":[{"raw_affiliation_string":"Mayo Clinic Arizona, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005764203","display_name":"Steven Swanson","orcid":"https://orcid.org/0000-0002-5896-1037","observed_orcids":["https://orcid.org/0000-0002-5896-1037"]},"institutions":[{"id":"https://openalex.org/I4210152461","display_name":"Valleywise Health","ror":"https://ror.org/05tbp9v13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210152461"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott Swanson","raw_affiliation_strings":["Valleywise Health Medical Center, Phoenix, AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Valleywise Health Medical Center, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210152461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072295519","display_name":"Philomene Spadafore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]},{"id":"https://openalex.org/I4210152461","display_name":"Valleywise Health","ror":"https://ror.org/05tbp9v13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210152461"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philomene Spadafore","raw_affiliation_strings":["Mayo Clinic Arizona, Phoenix, AZ, USA","Valleywise Health Medical Center, Phoenix, AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Arizona, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210125099"]},{"raw_affiliation_string":"Valleywise Health Medical Center, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210152461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024378108","display_name":"Areta Kowal-Vern","orcid":"https://orcid.org/0000-0002-1916-7666","observed_orcids":["https://orcid.org/0000-0002-1916-7666"]},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]},{"id":"https://openalex.org/I4210152461","display_name":"Valleywise Health","ror":"https://ror.org/05tbp9v13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210152461"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Areta Kowal-Vern","raw_affiliation_strings":["Mayo Clinic Arizona, Phoenix, AZ, USA","The Arizona Burn Center, Phoenix, AZ","Valleywise Health Medical Center, Phoenix, AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Arizona, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210125099"]},{"raw_affiliation_string":"The Arizona Burn Center, Phoenix, AZ","institution_ids":[]},{"raw_affiliation_string":"Valleywise Health Medical Center, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210152461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048023112","display_name":"Kevin N Foster","orcid":"https://orcid.org/0000-0003-2250-8908","observed_orcids":["https://orcid.org/0000-0003-2250-8908"]},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]},{"id":"https://openalex.org/I4210152461","display_name":"Valleywise Health","ror":"https://ror.org/05tbp9v13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210152461"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin N. Foster","raw_affiliation_strings":["Mayo Clinic Arizona, Phoenix, AZ, USA","Valleywise Health Medical Center, Phoenix, AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Arizona, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210125099"]},{"raw_affiliation_string":"Valleywise Health Medical Center, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210152461"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103207549","display_name":"Marc R. Matthews","orcid":"https://orcid.org/0000-0003-0832-0562","observed_orcids":["https://orcid.org/0000-0003-0832-0562"]},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]},{"id":"https://openalex.org/I4210152461","display_name":"Valleywise Health","ror":"https://ror.org/05tbp9v13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210152461"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marc R. Matthews","raw_affiliation_strings":["Mayo Clinic Arizona, Phoenix, AZ, USA","Valleywise Health Medical Center, Phoenix, AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Arizona, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210125099"]},{"raw_affiliation_string":"Valleywise Health Medical Center, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I4210152461"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5067198824"],"corresponding_institution_ids":["https://openalex.org/I4210125099"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.2278,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.53294891,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"31","issue":"3","first_page":"229","last_page":"235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11467","display_name":"Trauma and Emergency Care Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10630","display_name":"Orthopedic Surgery and Rehabilitation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/upper-limb-amputation","display_name":"upper limb amputation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/burns","display_name":"burns","score":0.9440000057220459},{"id":"https://openalex.org/keywords/burn-center-patients","display_name":"burn center patients","score":0.7429999709129333},{"id":"https://openalex.org/keywords/limb-salvage","display_name":"limb salvage","score":0.7360000014305115},{"id":"https://openalex.org/keywords/escharotomy","display_name":"escharotomy","score":0.8830000162124634},{"id":"https://openalex.org/keywords/fasciotomy","display_name":"fasciotomy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9359999895095825},{"id":"https://openalex.org/keywords/wound-infection","display_name":"wound infection","score":0.6010000109672546},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.5419999957084656},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.9350000023841858},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.7300000190734863},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.8479999899864197},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9420055150985718},{"id":"https://openalex.org/C2776782833","wikidata":"https://www.wikidata.org/wiki/Q3454235","display_name":"Total body surface area","level":2,"score":0.7784748673439026},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.6109153032302856},{"id":"https://openalex.org/C2780110798","wikidata":"https://www.wikidata.org/wiki/Q2980337","display_name":"Trauma center","level":3,"score":0.5588379502296448},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.5342653393745422},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5315867066383362},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.5313036441802979},{"id":"https://openalex.org/C2778838822","wikidata":"https://www.wikidata.org/wiki/Q2151257","display_name":"Burn center","level":3,"score":0.4780564606189728},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.45096355676651},{"id":"https://openalex.org/C2776204877","wikidata":"https://www.wikidata.org/wiki/Q477415","display_name":"Amputation","level":2,"score":0.4200159013271332},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3374354839324951},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.2793620824813843},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.20900896191596985}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1177/22925503211042863","doi":"https://doi.org/10.1177/22925503211042863","is_oa":false,"landing_page_url":"https://doi.org/10.1177/22925503211042863","pdf_url":null,"source":{"id":"https://openalex.org/S4210203465","display_name":"Plastic Surgery","issn_l":"1195-2199","issn":["1195-2199","1918-1507","2292-5503","2292-5511"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic Surgery","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10467439","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10467439","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10467439/pdf/10.1177_22925503211042863.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plast Surg (Oakv)","raw_type":"Text"},{"id":"pmid:37654535","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37654535","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic surgery (Oakville, Ont.)","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10467439","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10467439","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10467439/pdf/10.1177_22925503211042863.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plast Surg (Oakv)","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3209562872.pdf","grobid_xml":"https://content.openalex.org/works/W3209562872.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W2005946213","https://openalex.org/W2013128460","https://openalex.org/W2013608038","https://openalex.org/W2034850633","https://openalex.org/W2041449722","https://openalex.org/W2093735250","https://openalex.org/W2171824023","https://openalex.org/W2185810035","https://openalex.org/W2507719830","https://openalex.org/W2605828130","https://openalex.org/W2740952607","https://openalex.org/W2803865546","https://openalex.org/W2899245488","https://openalex.org/W2941556286","https://openalex.org/W3009645892","https://openalex.org/W3096782819"],"related_works":["https://openalex.org/W2973066213","https://openalex.org/W2921351951","https://openalex.org/W4388458576","https://openalex.org/W2013608038","https://openalex.org/W2041449722","https://openalex.org/W4220871594","https://openalex.org/W2941556286","https://openalex.org/W2171824023","https://openalex.org/W2034850633","https://openalex.org/W2883599245"],"abstract_inverted_index":{"Introduction":[0],"Burn":[1,24],"center":[2],"patients":[3,54,65,105],"present":[4],"not":[5],"only":[6],"with":[7,29,71,112,150,163],"burn":[8,128],"injuries":[9,129],"but":[10],"also":[11],"necrotizing":[12],"infections,":[13],"purpura":[14],"fulminans,":[15],"frostbite,":[16],"toxic":[17],"epidermal":[18],"necrolysis,":[19],"chronic":[20],"wounds,":[21],"and":[22,88,107,117,121,125,168,179,206,214],"trauma.":[23],"surgeons":[25],"are":[26],"often":[27],"faced":[28],"the":[30,113,133,182,222],"need":[31],"to":[32,49,55,92,211],"amputate":[33],"when":[34],"limb":[35],"salvage":[36],"is":[37],"no":[38],"longer":[39,140],"a":[40],"viable":[41],"option.":[42],"The":[43,136],"purpose":[44],"of":[45,90],"this":[46],"study":[47],"was":[48,188],"determine":[50],"factors":[51],"which":[52],"predispose":[53],"extremity":[56,69,103,219],"amputations.":[57],"Methods:":[58],"This":[59],"retrospective":[60],"registry":[61],"review":[62],"(2000-2019)":[63],"compared":[64],"who":[66,73],"required":[67],"upper":[68,102,218],"amputations":[70,220],"those":[72],"did":[74],"not.":[75],"Cases":[76],"were":[77,100,130],"pair-matched":[78,109],"by":[79],"age,":[80],"sex,":[81],"percent":[82],"total":[83],"body":[84],"surface":[85],"area":[86],"(%TBSA),":[87],"type/location":[89],"injury":[91],"control":[93],"for":[94,217],"possible":[95],"confounding":[96],"variables.":[97],"Results:":[98],"There":[99],"77":[101,108],"amputee":[104],"(APs)":[106],"non-amputees":[110],"(NAPs)":[111],"median":[114],"age":[115],"45-":[116],"43-years,":[118],"%TBSA":[119],"21":[120],"10,":[122],"respectively;":[123],"second":[124],"third":[126],"degree":[127],"similar":[131,189],"in":[132,221],"2":[134],"groups.":[135],"AP":[137,223],"group":[138],"had":[139],"hospitalizations":[141,213],"(median":[142,156],"40":[143],"vs":[144,158,175,193],"15":[145],"days)":[146],"P":[147,184,197],"<":[148,185],".0001,":[149],"more":[151,165],"intensive":[152],"care":[153],"unit":[154],"days":[155],"28":[157],"18":[159],"days).":[160],"APs":[161],"presented":[162],"significantly":[164],"cardiac,":[166],"renal,":[167],"pulmonary":[169],"comorbidities,":[170],"acquired":[171],"infections":[172,209],"(61":[173],"[64%]":[174],"35":[176],"[36%]),":[177],"escharotomies,":[178],"fasciotomies":[180],"than":[181],"NAP,":[183],".0001.":[186],"Mortality":[187],"(AP":[190],"14":[191],"[18.2%]":[192],"NAP":[194],"9":[195],"[11.7%]),":[196],"=":[198],".26.":[199],"Conclusions:":[200],"Escharotomies,":[201],"fasciotomies,":[202],"sepsis,":[203],"pneumonia,":[204],"wound,":[205],"urinary":[207],"tract":[208],"contributed":[210],"prolonged":[212],"increased":[215],"risk":[216],"group.":[224]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2021-11-08T00:00:00"}