{"id":"https://openalex.org/W320951612","doi":null,"title":"DNA methylation profiles differ between juvenile and adult phase leaves of crab apple (Malus micromalus) seedling tree","display_name":"DNA methylation profiles differ between juvenile and adult phase leaves of crab apple (Malus micromalus) seedling tree","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W320951612","mag":"320951612"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.509.9563","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.509.9563","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.pakbs.org/pjbot/PDFs/40(3)/PJB40(3)1025.pdf","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://agris.fao.org/agris-search/search.do?recordID=PK2010001226","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113371510","display_name":"I. A. Hafiz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I. A. Hafiz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025021552","display_name":"Nadeem Akhtar Abbasi","orcid":"https://orcid.org/0000-0002-8043-1892","observed_orcids":["https://orcid.org/0000-0002-8043-1892"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nadeem Akhtar Abbasi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8043-1892","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085078019","display_name":"Touqeer Ahmad","orcid":"https://orcid.org/0000-0002-3730-3596","observed_orcids":["https://orcid.org/0000-0002-3730-3596"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Touqeer Ahmad","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3730-3596","affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Azhar R. Hussain","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Azhar R. Hussain","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.112,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.42766135,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.7275000214576721,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.7275000214576721,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.22669999301433563,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/malus-micromalus","display_name":"Malus micromalus","score":0.9179999828338623},{"id":"https://openalex.org/keywords/crabapple","display_name":"crabapple","score":0.9599999785423279},{"id":"https://openalex.org/keywords/methylation-sensitive-amplification-polymorphism","display_name":"methylation-sensitive amplification polymorphism","score":0.824999988079071},{"id":"https://openalex.org/keywords/de-novo-methylation","display_name":"de novo methylation","score":0.9340000152587891},{"id":"https://openalex.org/keywords/demethylation","display_name":"demethylation","score":0.8849999904632568},{"id":"https://openalex.org/keywords/seedling-leaves","display_name":"seedling leaves","score":0.7839999794960022},{"id":"https://openalex.org/keywords/plant-development","display_name":"plant development","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8096789121627808},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7844835519790649},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.5782337188720703},{"id":"https://openalex.org/C17757408","wikidata":"https://www.wikidata.org/wiki/Q4135516","display_name":"genomic DNA","level":3,"score":0.5530176162719727},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.529367208480835},{"id":"https://openalex.org/C2777162945","wikidata":"https://www.wikidata.org/wiki/Q5903773","display_name":"HpaII","level":5,"score":0.5203299522399902},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4755660891532898},{"id":"https://openalex.org/C128319531","wikidata":"https://www.wikidata.org/wiki/Q219715","display_name":"Restriction enzyme","level":3,"score":0.4743448793888092},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4591815173625946},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.45241779088974},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.32688388228416443},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.17859438061714172}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.509.9563","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.509.9563","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.pakbs.org/pjbot/PDFs/40(3)/PJB40(3)1025.pdf","raw_type":"text"},{"id":"mag:320951612","doi":null,"is_oa":true,"landing_page_url":"http://agris.fao.org/agris-search/search.do?recordID=PK2010001226","pdf_url":null,"source":{"id":"https://openalex.org/S2912753077","display_name":"Pakistan Journal of Botany","issn_l":"0556-3321","issn":["0556-3321","2070-3368"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4320800798","host_organization_name":"Pakistan Botanical Society","host_organization_lineage":["https://openalex.org/P4320800798"],"host_organization_lineage_names":["Pakistan Botanical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pakistan Journal of Botany","raw_type":null}],"best_oa_location":{"id":"mag:320951612","doi":null,"is_oa":true,"landing_page_url":"http://agris.fao.org/agris-search/search.do?recordID=PK2010001226","pdf_url":null,"source":{"id":"https://openalex.org/S2912753077","display_name":"Pakistan Journal of Botany","issn_l":"0556-3321","issn":["0556-3321","2070-3368"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4320800798","host_organization_name":"Pakistan Botanical Society","host_organization_lineage":["https://openalex.org/P4320800798"],"host_organization_lineage_names":["Pakistan Botanical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Pakistan Journal of Botany","raw_type":null},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W569951484","https://openalex.org/W1217268015","https://openalex.org/W1544893850","https://openalex.org/W1918587666","https://openalex.org/W1965428844","https://openalex.org/W1965468335","https://openalex.org/W1970589293","https://openalex.org/W1971930614","https://openalex.org/W1972120963","https://openalex.org/W1973869076","https://openalex.org/W1976346232","https://openalex.org/W1978637583","https://openalex.org/W1979197786","https://openalex.org/W1986911157","https://openalex.org/W1989920854","https://openalex.org/W1993104666","https://openalex.org/W2002985774","https://openalex.org/W2004234608","https://openalex.org/W2024867035","https://openalex.org/W2061008849","https://openalex.org/W2081195534","https://openalex.org/W2106294913","https://openalex.org/W2121417064","https://openalex.org/W2133653599","https://openalex.org/W2144634347","https://openalex.org/W2146647814","https://openalex.org/W2148300616","https://openalex.org/W2187478870","https://openalex.org/W2335527890","https://openalex.org/W2364626012"],"related_works":["https://openalex.org/W1248210597","https://openalex.org/W2144899489","https://openalex.org/W2054533705","https://openalex.org/W2004234608","https://openalex.org/W3040007560","https://openalex.org/W3013860004","https://openalex.org/W2025008594","https://openalex.org/W2742100003","https://openalex.org/W2001879770","https://openalex.org/W1975071385"],"abstract_inverted_index":{"Cytosine":[0],"methylation":[1,125,152,172],"has":[2],"been":[3,183],"implicated":[4],"in":[5,17,39,105,114,132,140,153,165,177],"regulation":[6],"of":[7,47,62,87,148,170,190],"gene":[8],"expression,":[9],"genomic":[10,54],"imprinting":[11],"and":[12,19,58,71,73],"chromatin":[13],"remodeling,":[14],"resulting":[15],"both":[16,178,201],"temporal":[18],"developmental":[20],"regulation.":[21],"In":[22,78],"the":[23,32,63,191],"present":[24,139],"study":[25],"methylation-sensitive":[26],"amplification":[27,85],"polymorphism":[28,204],"(MSAP)":[29],"associated":[30],"with":[31,68,90],"transition":[33],"from":[34,56,108,117,185,197,200],"juvenile":[35,57,109],"to":[36,181,187,206],"adult":[37,59,119,154,166],"phase":[38,60,110,120,134,142],"Malus":[40],"micromalus":[41],"was":[42,66],"explored":[43],"using":[44,75],"a":[45],"pair":[46],"restriction":[48,149],"endo-nucleases":[49],"EcoR":[50,69,91],"II,":[51],"Bst0.The":[52],"extracted":[53],"DNA":[55,143,171,199],"leaves":[61],"seedling":[64,192],"tree":[65],"digested":[67,111,118],"II":[70,92],"Bst0I,":[72],"amplified":[74,106,115,144],"eight":[76],"primers.":[77],"total":[79],"77":[80],"bands":[81,89,98,102,130,137],"were":[82,103,138],"amplified.":[83],"Post":[84],"digestion":[86],"these":[88,136],"or":[93],"Bst0":[94],"I":[95],"revealed":[96],"32":[97],"containing":[99],"CC(A/T)GG.":[100],"Six":[101],"absent":[104],"profiles":[107,195],"DNA,":[112,121],"appeared":[113],"products":[116],"indicating":[122],"de":[123],"novo":[124],"at":[126,173],"CC(A/T)GG":[127,174],"site.":[128],"Five":[129],"disappeared":[131],"Adult":[133],"while":[135],"Juvenile":[141],"profiles,":[145],"revealing":[146],"presence":[147],"site":[150],"without":[151],"phase.":[155,167],"These":[156],"results":[157],"are":[158],"suggestive":[159],"that":[160],"demethylation":[161],"may":[162],"have":[163,182],"occurred":[164],"Seventeen":[168],"motifs":[169],"remaining":[175],"similar":[176],"phases":[179,202],"seem":[180],"maintained":[184],"basal":[186],"crown":[188],"part":[189],"tree.":[193],"Amplified":[194],"produced":[196],"restricted":[198],"showed":[203],"due":[205],"differential":[207],"methylation.":[208]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}