{"id":"https://openalex.org/W3209507106","doi":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","title":"The ILEUS Study: A Phase 2 Randomized Controlled Trial Investigating Alvimopan for Enhanced Gastrointestinal Recovery after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy","display_name":"The ILEUS Study: A Phase 2 Randomized Controlled Trial Investigating Alvimopan for Enhanced Gastrointestinal Recovery after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy","publication_year":2021,"publication_date":"2021-10-22","ids":{"openalex":"https://openalex.org/W3209507106","doi":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","mag":"3209507106"},"language":"en","primary_location":{"id":"doi:10.1016/j.jamcollsurg.2021.08.503","doi":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","pdf_url":null,"source":{"id":"https://openalex.org/S134316426","display_name":"Journal of the American College of Surgeons","issn_l":"1072-7515","issn":["1072-7515","1879-1190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Surgeons","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006371106","display_name":"Joel Micah Baumgartner","orcid":"https://orcid.org/0000-0001-5381-4751","observed_orcids":["https://orcid.org/0000-0001-5381-4751"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joel M. Baumgartner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115603968","display_name":"Ruifeng Chen","orcid":"https://orcid.org/0000-0002-9894-475X","observed_orcids":["https://orcid.org/0000-0002-9894-475X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ruifeng Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072839298","display_name":"Karen S. Messer","orcid":"https://orcid.org/0000-0002-9298-2413","observed_orcids":["https://orcid.org/0000-0002-9298-2413"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karen Messer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038318195","display_name":"Jula Veerapong","orcid":"https://orcid.org/0000-0002-6124-2586","observed_orcids":["https://orcid.org/0000-0002-6124-2586"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jula Veerapong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010201577","display_name":"Kaitlyn Jane Kelly","orcid":"https://orcid.org/0000-0001-9999-038X","observed_orcids":["https://orcid.org/0000-0001-9999-038X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kaitlyn J. Kelly","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113792269","display_name":"Sonia L. Ramamoorthy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sonia Ramamoorthy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5089839809","display_name":"Andrew M. Lowy","orcid":"https://orcid.org/0000-0002-7106-0735","observed_orcids":["https://orcid.org/0000-0002-7106-0735"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew M. Lowy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":{"value":3600,"currency":"USD","value_usd":3600},"fwci":0.2365,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.54849688,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"233","issue":"5","first_page":"e186","last_page":"e187"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.09650000184774399,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alvimopan","display_name":"alvimopan","score":0.9950000047683716},{"id":"https://openalex.org/keywords/gastrointestinal-function-recovery","display_name":"gastrointestinal function recovery","score":0.4749999940395355},{"id":"https://openalex.org/keywords/postoperative-ileus","display_name":"postoperative ileus","score":0.8040000200271606},{"id":"https://openalex.org/keywords/cytoreductive-surgery","display_name":"cytoreductive surgery","score":0.9670000076293945},{"id":"https://openalex.org/keywords/hyperthermic-intraperitoneal-chemotherapy","display_name":"hyperthermic intraperitoneal chemotherapy","score":0.996999979019165},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.5849999785423279},{"id":"https://openalex.org/keywords/opioid-induced-ileus","display_name":"opioid-induced ileus","score":0.453000009059906},{"id":"https://openalex.org/keywords/randomized-controlled-trials","display_name":"randomized controlled trials","score":0.6150000095367432}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9788504242897034},{"id":"https://openalex.org/C2994223192","wikidata":"https://www.wikidata.org/wiki/Q96375802","display_name":"Cytoreductive surgery","level":4,"score":0.778850257396698},{"id":"https://openalex.org/C2777125728","wikidata":"https://www.wikidata.org/wiki/Q738153","display_name":"Ileus","level":2,"score":0.706277072429657},{"id":"https://openalex.org/C2779458272","wikidata":"https://www.wikidata.org/wiki/Q612526","display_name":"Hyperthermic intraperitoneal chemotherapy","level":5,"score":0.6705507636070251},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6033691763877869},{"id":"https://openalex.org/C3019901188","wikidata":"https://www.wikidata.org/wiki/Q612526","display_name":"Intraperitoneal chemotherapy","level":4,"score":0.5436444282531738},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5432989597320557},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4748440086841583},{"id":"https://openalex.org/C2910703660","wikidata":"https://www.wikidata.org/wiki/Q738153","display_name":"Postoperative ileus","level":2,"score":0.4352883994579315},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3723672330379486},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19275951385498047},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1171761155128479},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jamcollsurg.2021.08.503","doi":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","pdf_url":null,"source":{"id":"https://openalex.org/S134316426","display_name":"Journal of the American College of Surgeons","issn_l":"1072-7515","issn":["1072-7515","1879-1190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Surgeons","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jamcollsurg.2021.08.503","doi":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jamcollsurg.2021.08.503","pdf_url":null,"source":{"id":"https://openalex.org/S134316426","display_name":"Journal of the American College of Surgeons","issn_l":"1072-7515","issn":["1072-7515","1879-1190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Surgeons","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4295761695","https://openalex.org/W2014019681","https://openalex.org/W2118983350","https://openalex.org/W2944804337","https://openalex.org/W2042192811","https://openalex.org/W2765685142","https://openalex.org/W2001695765","https://openalex.org/W7100018781","https://openalex.org/W4242451263","https://openalex.org/W4232238307"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2021-11-08T00:00:00"}