{"id":"https://openalex.org/W3209444792","doi":"https://doi.org/10.1002/rcr2.870","title":"Recurrent pneumothoraces with diffuse small ground\u2010glass and solid nodules","display_name":"Recurrent pneumothoraces with diffuse small ground\u2010glass and solid nodules","publication_year":2021,"publication_date":"2021-10-28","ids":{"openalex":"https://openalex.org/W3209444792","doi":"https://doi.org/10.1002/rcr2.870","mag":"3209444792","pmid":"https://pubmed.ncbi.nlm.nih.gov/34745633","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8552089"},"language":"en","primary_location":{"id":"doi:10.1002/rcr2.870","doi":"https://doi.org/10.1002/rcr2.870","is_oa":true,"landing_page_url":"https://doi.org/10.1002/rcr2.870","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.870","source":{"id":"https://openalex.org/S2764822511","display_name":"Respirology Case Reports","issn_l":"2051-3380","issn":["2051-3380"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology Case Reports","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W3209444792"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.870","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101844399","display_name":"Sandra Li Yan Hui","orcid":"https://orcid.org/0000-0003-3002-1489","observed_orcids":["https://orcid.org/0000-0003-3002-1489"]},"institutions":[{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Li Yan Sandra Hui","raw_affiliation_strings":["Department of Respiratory and Critical Care Medicine, Changi General Hospital, Singapore"],"raw_orcid":"https://orcid.org/0000-0003-3002-1489","affiliations":[{"raw_affiliation_string":"Department of Respiratory and Critical Care Medicine, Changi General Hospital, Singapore","institution_ids":["https://openalex.org/I2802225915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037012634","display_name":"Xin Min Cheng","orcid":"https://orcid.org/0000-0002-2458-2127","observed_orcids":["https://orcid.org/0000-0002-2458-2127","https://orcid.org/0000-0002-2598-8380"]},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Xin Min Cheng","raw_affiliation_strings":["Department of Anatomical Pathology, Singapore General Hospital, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomical Pathology, Singapore General Hospital, Singapore","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053458606","display_name":"Ing Xiang Soo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147238","display_name":"National Heart Centre Singapore","ror":"https://ror.org/04f8k9513","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4210147238"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Ing Xiang Soo","raw_affiliation_strings":["Department of Cardiothoracic Surgery, National Heart Centre, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiothoracic Surgery, National Heart Centre, Singapore","institution_ids":["https://openalex.org/I4210147238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108693302","display_name":"Su Ying Low","orcid":"https://orcid.org/0009-0001-7954-7847","observed_orcids":["https://orcid.org/0009-0001-7954-7847"]},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Su Ying Low","raw_affiliation_strings":["Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore","institution_ids":["https://openalex.org/I2251586001"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101844399"],"corresponding_institution_ids":["https://openalex.org/I2802225915"],"apc_list":{"value":1000,"currency":"USD","value_usd":1000},"apc_paid":{"value":1000,"currency":"USD","value_usd":1000},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"12","first_page":"e0870","last_page":"e0870"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12049","display_name":"Tuberous Sclerosis Complex Research","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12049","display_name":"Tuberous Sclerosis Complex Research","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13759","display_name":"Medical Imaging and Pathology Studies","score":0.01889999955892563,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11571","display_name":"Sarcoidosis and Beryllium Toxicity Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tuberous-sclerosis-complex","display_name":"tuberous sclerosis complex","score":0.9919999837875366},{"id":"https://openalex.org/keywords/lymphangioleiomyomatosis","display_name":"lymphangioleiomyomatosis","score":0.9369999766349792},{"id":"https://openalex.org/keywords/recurrent-pneumothorax","display_name":"recurrent pneumothorax","score":0.9879999756813049},{"id":"https://openalex.org/keywords/ground-glass-nodules","display_name":"ground-glass nodules","score":0.9769999980926514},{"id":"https://openalex.org/keywords/solid-nodules","display_name":"solid nodules","score":0.8289999961853027},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.6779999732971191},{"id":"https://openalex.org/keywords/miliary-tuberculosis","display_name":"miliary tuberculosis","score":0.9089999794960022},{"id":"https://openalex.org/keywords/alveolar-type-ii-cells","display_name":"alveolar type II cells","score":0.7609999775886536},{"id":"https://openalex.org/keywords/radiological-features","display_name":"radiological features","score":0.7279999852180481},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.8629999756813049}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8629757165908813},{"id":"https://openalex.org/C2778980267","wikidata":"https://www.wikidata.org/wiki/Q1362721","display_name":"Tuberous sclerosis","level":2,"score":0.8596583604812622},{"id":"https://openalex.org/C2779997425","wikidata":"https://www.wikidata.org/wiki/Q1878759","display_name":"Lymphangioleiomyomatosis","level":3,"score":0.5868731737136841},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5655815601348877},{"id":"https://openalex.org/C2777001051","wikidata":"https://www.wikidata.org/wiki/Q3150728","display_name":"Ground-glass opacity","level":4,"score":0.5520114898681641},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.44077789783477783},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3402601480484009},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06764853000640869},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1002/rcr2.870","doi":"https://doi.org/10.1002/rcr2.870","is_oa":true,"landing_page_url":"https://doi.org/10.1002/rcr2.870","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.870","source":{"id":"https://openalex.org/S2764822511","display_name":"Respirology Case Reports","issn_l":"2051-3380","issn":["2051-3380"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:7456293","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8552089","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:34745633","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34745633","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology case reports","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:8552089","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8552089/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirol Case Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b3d1233ffcf2454892b811ded6386e38","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b3d1233ffcf2454892b811ded6386e38","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Respirology Case Reports, Vol 9, Iss 12, Pp n/a-n/a (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/rcr2.870","doi":"https://doi.org/10.1002/rcr2.870","is_oa":true,"landing_page_url":"https://doi.org/10.1002/rcr2.870","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcr2.870","source":{"id":"https://openalex.org/S2764822511","display_name":"Respirology Case Reports","issn_l":"2051-3380","issn":["2051-3380"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respirology Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3209444792.pdf","grobid_xml":"https://content.openalex.org/works/W3209444792.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W310998523","https://openalex.org/W1896058224","https://openalex.org/W1990933597","https://openalex.org/W1999479808","https://openalex.org/W2037333570","https://openalex.org/W2075826421","https://openalex.org/W2085696639","https://openalex.org/W2086788103","https://openalex.org/W2106938134","https://openalex.org/W2133130744","https://openalex.org/W2138424126","https://openalex.org/W2171884143","https://openalex.org/W2330564907","https://openalex.org/W2352690127","https://openalex.org/W2361787858","https://openalex.org/W2571669577","https://openalex.org/W2884278367","https://openalex.org/W3107557487"],"related_works":["https://openalex.org/W2010479702","https://openalex.org/W2138424126","https://openalex.org/W4406693283","https://openalex.org/W7129350896","https://openalex.org/W2220199078","https://openalex.org/W2626336722","https://openalex.org/W4220860331","https://openalex.org/W310998523","https://openalex.org/W2502964467"],"abstract_inverted_index":{"Multifocal":[0],"micronodular":[1],"pneumocyte":[2],"hyperplasia":[3],"(MMPH)":[4],"is":[5,26,67,96,102],"the":[6,107],"lesser":[7],"known":[8],"pulmonary":[9],"manifestation":[10],"of":[11,44,72,79,112],"tuberous":[12,120],"sclerosis.":[13],"It":[14],"manifests":[15],"radiologically":[16],"as":[17,28,48],"diffuse":[18],"small":[19],"ground-glass":[20],"and":[21,53,109,123],"solid":[22],"nodules.":[23],"Accurate":[24],"diagnosis":[25,95],"essential":[27],"it":[29],"can":[30,57],"be":[31],"mistaken":[32],"for":[33],"miliary":[34],"tuberculosis":[35],"or":[36],"malignant":[37],"lesions":[38],"which":[39],"necessitates":[40],"specific":[41],"treatment.":[42],"Constellation":[43],"radiological":[45,108],"features":[46,111],"such":[47],"multicentric":[49],"disease":[50],"at":[51],"onset":[52],"stability":[54],"over":[55],"time":[56],"help":[58],"to":[59,82],"distinguish":[60],"MMPH":[61,66,85,113],"from":[62],"its":[63,91],"differentials.":[64,92],"Histologically,":[65],"characterized":[68],"by":[69],"hamartomatous":[70],"proliferation":[71],"type":[73],"II":[74],"pneumocytes":[75],"with":[76,117],"a":[77,87,115],"lack":[78],"high":[80],"nuclear":[81],"cytoplasmic":[83],"ratio.":[84],"confers":[86],"benign":[88],"prognosis":[89],"unlike":[90],"Therefore,":[93],"accurate":[94],"paramount":[97],"in":[98,114],"ensuring":[99],"appropriate":[100],"care":[101],"delivered.":[103],"Here,":[104],"we":[105],"describe":[106],"histological":[110],"patient":[116],"genetically":[118],"proven":[119],"sclerosis":[121],"complex":[122],"co-existing":[124],"lymphangioleiomyomatosis.":[125]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2021-11-08T00:00:00"}
