{"id":"https://openalex.org/W3208615839","doi":"https://doi.org/10.1002/mc.23363","title":"PARP5B is required for nonhomologous end joining during tumorigenesis in vivo","display_name":"PARP5B is required for nonhomologous end joining during tumorigenesis in vivo","publication_year":2021,"publication_date":"2021-10-28","ids":{"openalex":"https://openalex.org/W3208615839","doi":"https://doi.org/10.1002/mc.23363","mag":"3208615839","pmid":"https://pubmed.ncbi.nlm.nih.gov/34710250"},"language":"en","primary_location":{"id":"doi:10.1002/mc.23363","doi":"https://doi.org/10.1002/mc.23363","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mc.23363","pdf_url":null,"source":{"id":"https://openalex.org/S133439003","display_name":"Molecular Carcinogenesis","issn_l":"0899-1987","issn":["0899-1987","1098-2744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Carcinogenesis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1002/mc.23363","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023519598","display_name":"Jianchun Wu","orcid":"https://orcid.org/0000-0002-6878-7394","observed_orcids":["https://orcid.org/0000-0002-6878-7394"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianchun Wu","raw_affiliation_strings":["Department of Diagnostic Sciences University of Illinois Cancer Center Chicago Illinois USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Sciences University of Illinois Cancer Center Chicago Illinois USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035689487","display_name":"David L. Crowe","orcid":"https://orcid.org/0000-0003-0941-2602","observed_orcids":["https://orcid.org/0000-0003-0941-2602"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David L. Crowe","raw_affiliation_strings":["Department of Diagnostic Sciences University of Illinois Cancer Center Chicago Illinois USA"],"raw_orcid":"https://orcid.org/0000-0003-0941-2602","affiliations":[{"raw_affiliation_string":"Department of Diagnostic Sciences University of Illinois Cancer Center Chicago Illinois USA","institution_ids":["https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5035689487"],"corresponding_institution_ids":["https://openalex.org/I39422238"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":{"value":4000,"currency":"USD","value_usd":4000},"fwci":0.273,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.56486612,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"61","issue":"1","first_page":"85","last_page":"98"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.9330999851226807,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.9330999851226807,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.06530000269412994,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-homologous-end-joining","display_name":"non-homologous end joining","score":0.9629999995231628},{"id":"https://openalex.org/keywords/double-strand-break-repair","display_name":"DNA double-strand break repair","score":0.7950000166893005},{"id":"https://openalex.org/keywords/head-and-neck-squamous-cell-carcinoma","display_name":"head and neck squamous cell carcinoma","score":0.9620000123977661},{"id":"https://openalex.org/keywords/parp-inhibitors","display_name":"PARP inhibitors","score":0.8169999718666077},{"id":"https://openalex.org/keywords/xav939","display_name":"XAV939","score":0.9660000205039978},{"id":"https://openalex.org/keywords/homologous-recombination","display_name":"homologous recombination","score":0.7749999761581421},{"id":"https://openalex.org/keywords/atr-signaling","display_name":"ATR signaling","score":0.5550000071525574},{"id":"https://openalex.org/keywords/atm-signaling","display_name":"ATM signaling","score":0.7170000076293945},{"id":"https://openalex.org/keywords/nbs1","display_name":"NBS1","score":0.6909999847412109},{"id":"https://openalex.org/keywords/cancer-stem-cells","display_name":"cancer stem cells","score":0.7329999804496765},{"id":"https://openalex.org/keywords/etoposide","display_name":"etoposide","score":0.675000011920929},{"id":"https://openalex.org/keywords/dna-damage-response","display_name":"DNA damage response","score":0.5109999775886536},{"id":"https://openalex.org/keywords/targeted-cancer-therapy","display_name":"targeted cancer therapy","score":0.609000027179718},{"id":"https://openalex.org/keywords/carcinogen-induced-tumors","display_name":"carcinogen-induced tumors","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8580806851387024},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.6058292984962463},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.6029559969902039},{"id":"https://openalex.org/C34688535","wikidata":"https://www.wikidata.org/wiki/Q418732","display_name":"Proliferating cell nuclear antigen","level":3,"score":0.5815843939781189},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5644773840904236},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5530557632446289},{"id":"https://openalex.org/C2775984157","wikidata":"https://www.wikidata.org/wiki/Q18035037","display_name":"Rad50","level":5,"score":0.5463672876358032},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.5333592295646667},{"id":"https://openalex.org/C182979987","wikidata":"https://www.wikidata.org/wiki/Q3907241","display_name":"Poly ADP ribose polymerase","level":4,"score":0.5295864939689636},{"id":"https://openalex.org/C2779012473","wikidata":"https://www.wikidata.org/wiki/Q3235015","display_name":"RAD51","level":4,"score":0.5223432779312134},{"id":"https://openalex.org/C102744134","wikidata":"https://www.wikidata.org/wiki/Q22280388","display_name":"Homologous recombination","level":3,"score":0.4522072970867157},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.43290090560913086},{"id":"https://openalex.org/C113271649","wikidata":"https://www.wikidata.org/wiki/Q2565234","display_name":"Replication protein A","level":5,"score":0.4172021746635437},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3620779514312744},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.3594534993171692},{"id":"https://openalex.org/C82381507","wikidata":"https://www.wikidata.org/wiki/Q416878","display_name":"Polymerase","level":3,"score":0.29508233070373535},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.241077721118927},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2033737599849701},{"id":"https://openalex.org/C94966510","wikidata":"https://www.wikidata.org/wiki/Q2252764","display_name":"DNA-binding protein","level":4,"score":0.12687313556671143},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1038171648979187},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.09753769636154175}],"mesh":[{"descriptor_ui":"D000073658","descriptor_name":"Loss of Function Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077195","descriptor_name":"Squamous Cell Carcinoma of Head and Neck","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D000077195","descriptor_name":"Squamous Cell Carcinoma of Head and Neck","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000077195","descriptor_name":"Squamous Cell Carcinoma of Head and Neck","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000077195","descriptor_name":"Squamous Cell Carcinoma of Head and Neck","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002273","descriptor_name":"Carcinogens","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005047","descriptor_name":"Etoposide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005047","descriptor_name":"Etoposide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006575","descriptor_name":"Heterocyclic Compounds, 3-Ring","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006575","descriptor_name":"Heterocyclic Compounds, 3-Ring","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D038501","descriptor_name":"Tankyrases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D038501","descriptor_name":"Tankyrases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059766","descriptor_name":"DNA End-Joining Repair","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/mc.23363","doi":"https://doi.org/10.1002/mc.23363","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mc.23363","pdf_url":null,"source":{"id":"https://openalex.org/S133439003","display_name":"Molecular Carcinogenesis","issn_l":"0899-1987","issn":["0899-1987","1098-2744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Carcinogenesis","raw_type":"journal-article"},{"id":"pmid:34710250","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34710250","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular carcinogenesis","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/mc.23363","doi":"https://doi.org/10.1002/mc.23363","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mc.23363","pdf_url":null,"source":{"id":"https://openalex.org/S133439003","display_name":"Molecular Carcinogenesis","issn_l":"0899-1987","issn":["0899-1987","1098-2744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Carcinogenesis","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.7699999809265137,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2253496837","display_name":null,"funder_award_id":"DE 14283","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"}],"funders":[{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W771597756","https://openalex.org/W1571953570","https://openalex.org/W1575178924","https://openalex.org/W1973268287","https://openalex.org/W1992383407","https://openalex.org/W2022590214","https://openalex.org/W2025572488","https://openalex.org/W2039881995","https://openalex.org/W2044271955","https://openalex.org/W2046136351","https://openalex.org/W2057023085","https://openalex.org/W2057257265","https://openalex.org/W2061197983","https://openalex.org/W2067427915","https://openalex.org/W2070758111","https://openalex.org/W2092672926","https://openalex.org/W2097228429","https://openalex.org/W2110321854","https://openalex.org/W2111072547","https://openalex.org/W2124037118","https://openalex.org/W2155169828","https://openalex.org/W2156442575","https://openalex.org/W2157899948","https://openalex.org/W2158389792","https://openalex.org/W2158485828","https://openalex.org/W2160305147","https://openalex.org/W2212776653","https://openalex.org/W2253016623","https://openalex.org/W2279609010","https://openalex.org/W2394589397","https://openalex.org/W2416703957","https://openalex.org/W2444594224","https://openalex.org/W2510690280","https://openalex.org/W2523005380","https://openalex.org/W2569771446","https://openalex.org/W2594301310","https://openalex.org/W2597062310","https://openalex.org/W2750281062","https://openalex.org/W2755843571","https://openalex.org/W2761827619","https://openalex.org/W2789082421","https://openalex.org/W2810748925","https://openalex.org/W2902300797","https://openalex.org/W2909403286","https://openalex.org/W2943776844","https://openalex.org/W2947826965","https://openalex.org/W2951114010","https://openalex.org/W2952852296","https://openalex.org/W2955620588","https://openalex.org/W2969878350","https://openalex.org/W2989887645","https://openalex.org/W6667439359"],"related_works":["https://openalex.org/W2142658272","https://openalex.org/W2798259319","https://openalex.org/W2930305328","https://openalex.org/W2570196263","https://openalex.org/W2135536383","https://openalex.org/W2042685981","https://openalex.org/W3188946927","https://openalex.org/W2165308870","https://openalex.org/W4366463407","https://openalex.org/W2102971019"],"abstract_inverted_index":{"Poly(ADP-ribose)":[0],"polymerases":[1],"(PARP)":[2],"act":[3],"as":[4],"DNA":[5,160],"damage":[6],"sensors":[7],"that":[8,196],"produce":[9],"poly(ADP-ribose)":[10],"(PAR)":[11],"chains":[12],"at":[13,159],"double-strand":[14,122],"breaks,":[15],"facilitating":[16],"the":[17,43,111,169,187],"recruitment":[18],"of":[19,45,99,165,189],"repair":[20,157],"factors.":[21],"Cancers":[22],"with":[23,168],"homologous":[24],"recombination":[25],"defects":[26],"are":[27,52],"sensitive":[28],"to":[29,131],"small":[30],"molecule":[31],"PARP":[32],"inhibitors.":[33],"Despite":[34],"PARP5B":[35,64,81,100,116,134,170,197],"gene":[36],"copy":[37],"number":[38],"changes":[39],"in":[40,67,70,177,183],"many":[41],"cancers,":[42],"effects":[44,188],"this":[46,58],"genetic":[47],"alteration":[48],"on":[49],"tumor":[50,84,88,118],"phenotype":[51],"largely":[53],"unknown.":[54],"To":[55],"better":[56],"understand":[57],"clinical":[59],"finding,":[60],"we":[61],"characterized":[62],"a":[63,68,138],"null":[65,117,135],"mutation":[66],"carcinogen-induced":[69],"vivo":[71],"head":[72],"and":[73,90,92,96,104,109,127,152,175],"neck":[74],"squamous":[75],"cell":[76,94,114,148],"carcinoma":[77],"(SCC)":[78],"model.":[79],"Reduced":[80],"expression":[82],"inhibited":[83,93,186],"growth,":[85],"induced":[86,173],"primary":[87],"differentiation":[89],"apoptosis,":[91],"proliferation":[95],"metastasis.":[97],"Loss":[98],"expression-induced":[101],"ataxia":[102],"telangiectasia":[103],"Rad3":[105],"related":[106],"(ATR)":[107],"activation":[108],"depleted":[110],"cancer":[112,202],"stem":[113],"fraction.":[115],"cells":[119,185],"lacked":[120],"53BP1+":[121],"break":[123],"foci,":[124],"ATM":[125],"activation,":[126],"p53":[128],"induction":[129],"compared":[130],"PARP5B+/+":[132],"cancers.":[133],"SCC":[136,179],"expresses":[137],"multiprotein":[139],"complex":[140],"containing":[141],"PML,":[142],"pRPA,":[143],"Rad50,":[144],"Rad51,":[145],"XRCC1,":[146],"proliferating":[147],"nuclear":[149],"antigen":[150],"(PCNA),":[151],"Mcm2,":[153],"suggesting":[154],"an":[155],"HR-mediated":[156],"mechanism":[158],"replication":[161],"foci.":[162],"Low":[163],"doses":[164],"etoposide":[166],"combined":[167],"inhibitor":[171],"XAV939":[172],"senescence":[174],"apoptosis":[176],"human":[178],"lines.":[180],"NBS1":[181],"overexpression":[182],"these":[184],"low-dose":[190],"etoposide/XAV939":[191],"treatment.":[192],"Our":[193],"results":[194],"indicate":[195],"inhibition":[198],"is":[199],"new":[200],"targeted":[201],"therapy.":[203]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-11-08T00:00:00"}