{"id":"https://openalex.org/W32082291","doi":null,"title":"[How and when is topical treatment applied into the ear?].","display_name":"[How and when is topical treatment applied into the ear?].","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W32082291","mag":"32082291","pmid":"https://pubmed.ncbi.nlm.nih.gov/21888048"},"language":"fi","primary_location":{"id":"pmid:21888048","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21888048","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Duodecim; laaketieteellinen aikakauskirja","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070645560","display_name":"Erkki Hopsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153619","display_name":"Kymenlaakson keskussairaala","ror":"https://ror.org/05mmga691","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210153619"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Erkki Hopsu","raw_affiliation_strings":["Kymenlaakson keskussairaala, korva-, nen\u00e4- ja kurkutaudit, Kotka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kymenlaakson keskussairaala, korva-, nen\u00e4- ja kurkutaudit, Kotka","institution_ids":["https://openalex.org/I4210153619"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074166450","display_name":"Mervi N\u00e4rki\u00f6\u2010M\u00e4kel\u00e4","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mervi N\u00e4rki\u00f6-M\u00e4kel\u00e4","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5041686879","display_name":"Juha Tapio Silvola","orcid":"https://orcid.org/0000-0001-7615-096X","observed_orcids":["https://orcid.org/0000-0001-7615-096X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juha Silvola","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00335237,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"127","issue":"14","first_page":"1470","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10861","display_name":"Ear Surgery and Otitis Media","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10861","display_name":"Ear Surgery and Otitis Media","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12297","display_name":"Otolaryngology and Infectious Diseases","score":0.032099999487400055,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14326","display_name":"Ear and Head Tumors","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/otitis-externa","display_name":"otitis externa","score":0.8550000190734863},{"id":"https://openalex.org/keywords/chronic-otitis-media","display_name":"chronic otitis media","score":0.9470000267028809},{"id":"https://openalex.org/keywords/ear-drops","display_name":"ear drops","score":0.8569999933242798},{"id":"https://openalex.org/keywords/fungal-ear-infection","display_name":"fungal ear infection","score":0.5950000286102295},{"id":"https://openalex.org/keywords/ear-canal-cleaning","display_name":"ear canal cleaning","score":0.6970000267028809},{"id":"https://openalex.org/keywords/ear-canal-irrigation","display_name":"ear canal irrigation","score":0.4339999854564667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.707504391670227},{"id":"https://openalex.org/C23795335","wikidata":"https://www.wikidata.org/wiki/Q1790295","display_name":"Suction","level":2,"score":0.6006967425346375},{"id":"https://openalex.org/C3019325995","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Systemic antibiotics","level":3,"score":0.5762092471122742},{"id":"https://openalex.org/C2776439223","wikidata":"https://www.wikidata.org/wiki/Q480700","display_name":"Otitis","level":2,"score":0.5458389520645142},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5416269302368164},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5303789973258972},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.515933096408844},{"id":"https://openalex.org/C3019630126","wikidata":"https://www.wikidata.org/wiki/Q258328","display_name":"Auditory canal","level":2,"score":0.4776974022388458},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.46030595898628235},{"id":"https://openalex.org/C2777846895","wikidata":"https://www.wikidata.org/wiki/Q501553","display_name":"Middle ear","level":2,"score":0.45055556297302246},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.44944527745246887},{"id":"https://openalex.org/C2779812621","wikidata":"https://www.wikidata.org/wiki/Q258328","display_name":"Ear canal","level":2,"score":0.4489332437515259},{"id":"https://openalex.org/C189539697","wikidata":"https://www.wikidata.org/wiki/Q1125312","display_name":"Microbiological culture","level":3,"score":0.41776132583618164},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3920183479785919},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3146059513092041},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.22278830409049988},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18329265713691711},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.14525538682937622},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09848842024803162},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.08837848901748657},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004424","descriptor_name":"Ear Canal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004431","descriptor_name":"Ear, External","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010032","descriptor_name":"Otitis Externa","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010032","descriptor_name":"Otitis Externa","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010033","descriptor_name":"Otitis Media","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010033","descriptor_name":"Otitis Media","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:21888048","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21888048","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Duodecim; laaketieteellinen aikakauskirja","raw_type":"Case Reports"},{"id":"mag:32082291","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21888048","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W2076495609","https://openalex.org/W2752977230","https://openalex.org/W2066107559","https://openalex.org/W2796061259","https://openalex.org/W2064602529","https://openalex.org/W2607232673","https://openalex.org/W2028010068","https://openalex.org/W2085487477","https://openalex.org/W2792549532","https://openalex.org/W2031277784","https://openalex.org/W2236156346","https://openalex.org/W2060098032","https://openalex.org/W2013482681","https://openalex.org/W2081769002","https://openalex.org/W2089486311","https://openalex.org/W2746569992","https://openalex.org/W2573203202","https://openalex.org/W2507412157","https://openalex.org/W2334010047","https://openalex.org/W2646467224","https://openalex.org/W2081345296","https://openalex.org/W2416403255","https://openalex.org/W2898030745","https://openalex.org/W2001045944","https://openalex.org/W2328173436","https://openalex.org/W1977457899","https://openalex.org/W1991211572","https://openalex.org/W2073506857","https://openalex.org/W2055740754","https://openalex.org/W2227711032","https://openalex.org/W2796205057","https://openalex.org/W2058145315","https://openalex.org/W2394702804"],"related_works":["https://openalex.org/W2330592919","https://openalex.org/W4309708462","https://openalex.org/W7061016029","https://openalex.org/W7208756180","https://openalex.org/W2044181321","https://openalex.org/W1512571721","https://openalex.org/W2536528834","https://openalex.org/W2914809312","https://openalex.org/W4290601259","https://openalex.org/W1827012806"],"abstract_inverted_index":{"Topical":[0],"treatment":[1,5,58],"is":[2,28,81,98],"the":[3,9,18,50,56,82,90],"first-line":[4],"for":[6,86],"inflammation":[7,51],"of":[8,20],"external":[10],"auditory":[11],"canal":[12,27],"and":[13,35,100],"chronic":[14],"otitis":[15],"media,":[16],"without":[17,66],"need":[19],"systemic":[21,67],"antimicrobial":[22],"drug":[23,64],"therapy.":[24],"The":[25],"ear":[26,73,79],"cleaned":[29],"mechanically,":[30],"by":[31,38],"rinsing":[32],"with":[33,55,72],"saline,":[34],"finally":[36],"dried":[37],"suction.":[39],"A":[40,75],"bacterial":[41,87],"or":[42,59],"fungal":[43,96],"culture":[44],"specimen":[45],"should":[46],"be":[47],"taken,":[48],"if":[49],"does":[52],"not":[53],"heal":[54],"first":[57],"recurs":[60],"rapidly.":[61],"High":[62],"local":[63],"levels":[65],"adverse":[68],"effects":[69],"are":[70],"achieved":[71],"drops.":[74],"combinatorial":[76],"broad-spectrum":[77],"antibiotic/corticosteroid":[78],"drop":[80],"most":[83,91],"effective":[84],"remedy":[85],"inflammation,":[88],"whereas":[89],"important":[92],"therapeutic":[93],"procedure":[94],"in":[95],"infections":[97],"cleaning":[99],"topical":[101],"medication.":[102]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}