{"id":"https://openalex.org/W3207741203","doi":"https://doi.org/10.1016/j.isci.2021.103268","title":"Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation","display_name":"Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation","publication_year":2021,"publication_date":"2021-10-14","ids":{"openalex":"https://openalex.org/W3207741203","doi":"https://doi.org/10.1016/j.isci.2021.103268","mag":"3207741203","pmid":"https://pubmed.ncbi.nlm.nih.gov/34761188","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8567388"},"language":"en","primary_location":{"id":"doi:10.1016/j.isci.2021.103268","doi":"https://doi.org/10.1016/j.isci.2021.103268","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.isci.2021.103268","pdf_url":"http://www.cell.com/article/S2589004221012372/pdf","source":{"id":"https://openalex.org/S2898358376","display_name":"iScience","issn_l":"2589-0042","issn":["2589-0042"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.cell.com/article/S2589004221012372/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050612324","display_name":"Maria Vistrup-Parry","orcid":"https://orcid.org/0000-0003-2176-2541","observed_orcids":["https://orcid.org/0000-0003-2176-2541"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Maria Vistrup-Parry","raw_affiliation_strings":["Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100326729","display_name":"Xudong Chen","orcid":"https://orcid.org/0000-0002-9433-3732","observed_orcids":["https://orcid.org/0000-0002-9433-3732"]},"institutions":[{"id":"https://openalex.org/I200769079","display_name":"Hong Kong University of Science and Technology","ror":"https://ror.org/00q4vv597","country_code":"HK","type":"education","lineage":["https://openalex.org/I200769079"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Xudong Chen","raw_affiliation_strings":["Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China","institution_ids":["https://openalex.org/I200769079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008840277","display_name":"Thea L. Johansen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Thea L. Johansen","raw_affiliation_strings":["Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043012005","display_name":"Sofie Bach","orcid":"https://orcid.org/0000-0002-3056-8532","observed_orcids":["https://orcid.org/0000-0002-3056-8532"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Sofie Bach","raw_affiliation_strings":["Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-3056-8532","affiliations":[{"raw_affiliation_string":"Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008202070","display_name":"Sara Charlotte Buch-Larsen","orcid":"https://orcid.org/0000-0001-6250-5467","observed_orcids":["https://orcid.org/0000-0001-6250-5467"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Sara C. Buch-Larsen","raw_affiliation_strings":["Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2801134892"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062421025","display_name":"Christian R. O. Bartling","orcid":"https://orcid.org/0000-0002-0602-4738","observed_orcids":["https://orcid.org/0000-0002-0602-4738"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Christian R.O. Bartling","raw_affiliation_strings":["Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-0602-4738","affiliations":[{"raw_affiliation_string":"Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012739846","display_name":"Chenxue Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200769079","display_name":"Hong Kong University of Science and Technology","ror":"https://ror.org/00q4vv597","country_code":"HK","type":"education","lineage":["https://openalex.org/I200769079"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Chenxue Ma","raw_affiliation_strings":["Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China","institution_ids":["https://openalex.org/I200769079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082697577","display_name":"Louise S. Clemmensen","orcid":"https://orcid.org/0000-0001-5313-2398","observed_orcids":["https://orcid.org/0000-0001-5313-2398"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Louise S. Clemmensen","raw_affiliation_strings":["Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009510298","display_name":"Michael Lund Nielsen","orcid":"https://orcid.org/0000-0002-0067-9039","observed_orcids":["https://orcid.org/0000-0002-0067-9039"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Michael L. Nielsen","raw_affiliation_strings":["Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2801134892"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100350849","display_name":"Mingjie Zhang","orcid":"https://orcid.org/0000-0001-9404-0190","observed_orcids":["https://orcid.org/0000-0001-9404-0190"]},"institutions":[{"id":"https://openalex.org/I200769079","display_name":"Hong Kong University of Science and Technology","ror":"https://ror.org/00q4vv597","country_code":"HK","type":"education","lineage":["https://openalex.org/I200769079"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Mingjie Zhang","raw_affiliation_strings":["Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China","Shenzhen Bay Laboratory, Gaoke Innovation Center, Guangqiao Road, Guangming District, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China","institution_ids":["https://openalex.org/I200769079"]},{"raw_affiliation_string":"Shenzhen Bay Laboratory, Gaoke Innovation Center, Guangqiao Road, Guangming District, Shenzhen, China","institution_ids":["https://openalex.org/I4210102541"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060992391","display_name":"Kristian Str\u00f8mgaard","orcid":"https://orcid.org/0000-0003-2206-4737","observed_orcids":["https://orcid.org/0000-0003-2206-4737"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"Kristian Str\u00f8mgaard","raw_affiliation_strings":["Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, 2100 Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5060992391"],"corresponding_institution_ids":["https://openalex.org/I124055696"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":0.9061,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.68423217,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"24","issue":"11","first_page":"103268","last_page":"103268"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psd-95","display_name":"PSD-95","score":1.0},{"id":"https://openalex.org/keywords/site-specific-phosphorylation","display_name":"site-specific phosphorylation","score":0.8769999742507935},{"id":"https://openalex.org/keywords/postsynaptic-density","display_name":"postsynaptic density","score":0.8840000033378601},{"id":"https://openalex.org/keywords/phase-separation","display_name":"phase separation","score":0.9649999737739563},{"id":"https://openalex.org/keywords/liquid-liquid-phase-separation","display_name":"liquid-liquid phase separation","score":0.7620000243186951},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.5709999799728394},{"id":"https://openalex.org/keywords/glun2b","display_name":"GluN2B","score":0.8629999756813049},{"id":"https://openalex.org/keywords/stargazin","display_name":"stargazin","score":0.996999979019165},{"id":"https://openalex.org/keywords/phosphoserine","display_name":"phosphoserine","score":0.6320000290870667},{"id":"https://openalex.org/keywords/scaffold-proteins","display_name":"scaffold proteins","score":0.703000009059906},{"id":"https://openalex.org/keywords/protein-complex-dynamics","display_name":"protein complex dynamics","score":0.3070000112056732}],"concepts":[{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.853326141834259},{"id":"https://openalex.org/C187541742","wikidata":"https://www.wikidata.org/wiki/Q4374336","display_name":"Postsynaptic density","level":4,"score":0.7958458065986633},{"id":"https://openalex.org/C53645450","wikidata":"https://www.wikidata.org/wiki/Q907093","display_name":"Scaffold protein","level":3,"score":0.6389291882514954},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.5989155173301697},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.5801871418952942},{"id":"https://openalex.org/C2780307904","wikidata":"https://www.wikidata.org/wiki/Q2701649","display_name":"Phosphoserine","level":4,"score":0.508637547492981},{"id":"https://openalex.org/C87325107","wikidata":"https://www.wikidata.org/wiki/Q7251493","display_name":"Protein phosphorylation","level":4,"score":0.4946601092815399},{"id":"https://openalex.org/C2780648746","wikidata":"https://www.wikidata.org/wiki/Q28208871","display_name":"Glutamatergic","level":4,"score":0.4915390908718109},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.49018412828445435},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.47029349207878113},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4639982581138611},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38329362869262695},{"id":"https://openalex.org/C2776414213","wikidata":"https://www.wikidata.org/wiki/Q183290","display_name":"Serine","level":3,"score":0.3650372624397278},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36345094442367554},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.33149290084838867},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.27962905168533325},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2610112428665161},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2586531937122345},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.19763311743736267},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07235908508300781}],"mesh":[],"locations_count":8,"locations":[{"id":"doi:10.1016/j.isci.2021.103268","doi":"https://doi.org/10.1016/j.isci.2021.103268","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.isci.2021.103268","pdf_url":"http://www.cell.com/article/S2589004221012372/pdf","source":{"id":"https://openalex.org/S2898358376","display_name":"iScience","issn_l":"2589-0042","issn":["2589-0042"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:7467322","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8567388","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8567388","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8567388","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"Text"},{"id":"pmid:34761188","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34761188","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire/b84cc1c4-736d-48dc-a471-5c86f65f4972","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/b84cc1c4-736d-48dc-a471-5c86f65f4972","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vistrup-Parry, M, Chen, X, Johansen, T L, Bach, S, Buch-Larsen, S C, Bartling, C R O, Ma, C, Clemmensen, L S, Nielsen, M L, Zhang, M & Stromgaard, K 2021, 'Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation', iScience, vol. 24, no. 11, 103268. https://doi.org/10.1016/j.isci.2021.103268","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:c0fa66c067824ad998d2b160f87425b6","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c0fa66c067824ad998d2b160f87425b6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"iScience, Vol 24, Iss 11, Pp 103268- (2021)","raw_type":"article"},{"id":"pmh:oai:repository.hkust.edu.hk:1783.1-115428","doi":null,"is_oa":false,"landing_page_url":"http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=2589-0042&rft.volume=24&rft.issue=(11)&rft.date=2021&rft.spage=&rft.aulast=Vistrup-Parry&rft.aufirst=&rft.atitle=Site-specific+phosphorylation+of+PSD-95+dynamically+regulates+the+postsynaptic+density+as+observed+by+phase+separation&rft.title=iScience","pdf_url":null,"source":{"id":"https://openalex.org/S4306401796","display_name":"Rare & Special e-Zone (The Hong Kong University of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200769079","host_organization_name":"Hong Kong University of Science and Technology","host_organization_lineage":["https://openalex.org/I200769079"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:repository.ust.hk:1783.1-115428","doi":null,"is_oa":false,"landing_page_url":"http://repository.ust.hk/ir/Record/1783.1-115428","pdf_url":null,"source":{"id":"https://openalex.org/S4306401796","display_name":"Rare & Special e-Zone (The Hong Kong University of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200769079","host_organization_name":"Hong Kong University of Science and Technology","host_organization_lineage":["https://openalex.org/I200769079"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/j.isci.2021.103268","doi":"https://doi.org/10.1016/j.isci.2021.103268","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.isci.2021.103268","pdf_url":"http://www.cell.com/article/S2589004221012372/pdf","source":{"id":"https://openalex.org/S2898358376","display_name":"iScience","issn_l":"2589-0042","issn":["2589-0042"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"iScience","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1537034788","display_name":null,"funder_award_id":"C6004\u201317G","funder_id":"https://openalex.org/F4320321592","funder_display_name":"Research Grants Council, University Grants Committee"},{"id":"https://openalex.org/G239714773","display_name":null,"funder_award_id":"AOE/M-09/12","funder_id":"https://openalex.org/F4320321592","funder_display_name":"Research Grants Council, University Grants Committee"},{"id":"https://openalex.org/G784548821","display_name":null,"funder_award_id":"NNF21OC0068550","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"}],"funders":[{"id":"https://openalex.org/F4320320904","display_name":"Croucher Foundation","ror":"https://ror.org/04741mc34"},{"id":"https://openalex.org/F4320321592","display_name":"Research Grants Council, University Grants Committee","ror":"https://ror.org/00djwmt25"},{"id":"https://openalex.org/F4320325957","display_name":"Novo Nordisk Fonden","ror":"https://ror.org/04txyc737"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W3207741203.pdf"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W1487695731","https://openalex.org/W1597375909","https://openalex.org/W1607154936","https://openalex.org/W1618384257","https://openalex.org/W1653383134","https://openalex.org/W1954241012","https://openalex.org/W1967117930","https://openalex.org/W1971780683","https://openalex.org/W1973268713","https://openalex.org/W1981000354","https://openalex.org/W1993385893","https://openalex.org/W1995989434","https://openalex.org/W2003236418","https://openalex.org/W2005354224","https://openalex.org/W2006458848","https://openalex.org/W2006786639","https://openalex.org/W2011573205","https://openalex.org/W2014235532","https://openalex.org/W2019592149","https://openalex.org/W2024210610","https://openalex.org/W2032787509","https://openalex.org/W2045295942","https://openalex.org/W2051947456","https://openalex.org/W2065989745","https://openalex.org/W2071318481","https://openalex.org/W2075621633","https://openalex.org/W2076508109","https://openalex.org/W2085978470","https://openalex.org/W2088239473","https://openalex.org/W2092442184","https://openalex.org/W2093573816","https://openalex.org/W2103994181","https://openalex.org/W2114659173","https://openalex.org/W2114691307","https://openalex.org/W2117242960","https://openalex.org/W2120587971","https://openalex.org/W2127325055","https://openalex.org/W2130190017","https://openalex.org/W2139066576","https://openalex.org/W2139503851","https://openalex.org/W2154626303","https://openalex.org/W2156370777","https://openalex.org/W2162151490","https://openalex.org/W2162353145","https://openalex.org/W2163266294","https://openalex.org/W2170621766","https://openalex.org/W2178843014","https://openalex.org/W2261521410","https://openalex.org/W2270583408","https://openalex.org/W2275622089","https://openalex.org/W2302440598","https://openalex.org/W2313617204","https://openalex.org/W2509111410","https://openalex.org/W2590568317","https://openalex.org/W2617704854","https://openalex.org/W2626266076","https://openalex.org/W2626881499","https://openalex.org/W2735227557","https://openalex.org/W2763278454","https://openalex.org/W2767503559","https://openalex.org/W2770631390","https://openalex.org/W2808325313","https://openalex.org/W2886239953","https://openalex.org/W2901130339","https://openalex.org/W2949014628","https://openalex.org/W2971594646","https://openalex.org/W2971667181","https://openalex.org/W3004042481"],"related_works":["https://openalex.org/W2735227557","https://openalex.org/W2074502837","https://openalex.org/W7132887416","https://openalex.org/W2509111410","https://openalex.org/W4247415478","https://openalex.org/W7125268873","https://openalex.org/W2743029692","https://openalex.org/W3011881660","https://openalex.org/W2410998830","https://openalex.org/W1984617454"],"abstract_inverted_index":{"Postsynaptic":[0],"density":[1,12],"protein":[2,8,61,107],"95":[3],"is":[4,28],"a":[5,56],"key":[6],"scaffolding":[7],"in":[9,48],"the":[10,39,75,99,105,127,138,145,148],"postsynaptic":[11],"of":[13,38,58,80,93,111,140,147],"excitatory":[14],"glutamatergic":[15],"neurons,":[16],"organizing":[17],"signaling":[18],"complexes":[19,82],"primarily":[20],"via":[21],"its":[22],"three":[23],"PSD-95/Discs-large/Zona":[24],"occludens":[25],"domains.":[26],"PSD-95":[27,53,81,141],"regulated":[29],"by":[30,120,142],"phosphorylation,":[31],"but":[32],"technical":[33],"challenges":[34],"have":[35,133],"limited":[36],"studies":[37],"molecular":[40],"details.":[41],"Here,":[42],"we":[43,132],"genetically":[44,121],"introduced":[45],"site-specific":[46],"phosphorylations":[47,67],"single,":[49],"tandem,":[50],"and":[51,54,74,83,104,125,144],"full-length":[52],"generated":[55],"total":[57],"11":[59],"phosphorylated":[60],"variants.":[62],"We":[63],"examined":[64],"how":[65],"these":[66],"affected":[68],"binding":[69],"to":[70],"known":[71],"interaction":[72],"partners":[73],"impact":[76,128],"on":[77,129],"phase":[78,96,114,130],"separation":[79,97,115],"identified":[84],"two":[85],"new":[86,135],"phosphorylation":[87,110,143],"sites":[88],"with":[89,98,116],"opposing":[90],"effects.":[91],"Phosphorylation":[92],"Ser78":[94],"inhibited":[95],"glutamate":[100],"receptor":[101],"subunit":[102],"GluN2B":[103],"auxiliary":[106],"stargazin,":[108],"whereas":[109],"Ser116":[112],"induced":[113],"stargazin":[117],"only.":[118],"Thus,":[119],"introducing":[122],"phosphoserine":[123],"site-specifically":[124],"exploring":[126],"separation,":[131],"provided":[134],"insights":[136],"into":[137],"regulation":[139],"dynamics":[146],"PSD.":[149]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-10-25T00:00:00"}
