{"id":"https://openalex.org/W3207281986","doi":"https://doi.org/10.1007/s43032-021-00761-6","title":"Effect of Curcumin on Glycaemic and Lipid Parameters in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","display_name":"Effect of Curcumin on Glycaemic and Lipid Parameters in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","publication_year":2021,"publication_date":"2021-10-15","ids":{"openalex":"https://openalex.org/W3207281986","doi":"https://doi.org/10.1007/s43032-021-00761-6","mag":"3207281986","pmid":"https://pubmed.ncbi.nlm.nih.gov/34655047"},"language":"en","primary_location":{"id":"doi:10.1007/s43032-021-00761-6","doi":"https://doi.org/10.1007/s43032-021-00761-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s43032-021-00761-6","pdf_url":null,"source":{"id":"https://openalex.org/S68157034","display_name":"Reproductive Sciences","issn_l":"1933-7191","issn":["1933-7191","1933-7205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019186060","display_name":"Luis E. Simental\u2010Mend\u00eda","orcid":"https://orcid.org/0000-0002-3617-4921","observed_orcids":["https://orcid.org/0000-0002-3617-4921"]},"institutions":[{"id":"https://openalex.org/I164915025","display_name":"Mexican Social Security Institute","ror":"https://ror.org/03xddgg98","country_code":"MX","type":"government","lineage":["https://openalex.org/I164915025"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Luis E. Simental-Mend\u00eda","raw_affiliation_strings":["Biomedical Research Unit, Mexican Social Security Institute, Durango, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Research Unit, Mexican Social Security Institute, Durango, Mexico","institution_ids":["https://openalex.org/I164915025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052449640","display_name":"Najeeb Zaheer Shah","orcid":"https://orcid.org/0000-0001-8946-4255","observed_orcids":["https://orcid.org/0000-0001-8946-4255"]},"institutions":[{"id":"https://openalex.org/I191240316","display_name":"University of Hull","ror":"https://ror.org/04nkhwh30","country_code":"GB","type":"education","lineage":["https://openalex.org/I191240316"]},{"id":"https://openalex.org/I69768126","display_name":"Hull York Medical School","ror":"https://ror.org/0003e4m70","country_code":"GB","type":"education","lineage":["https://openalex.org/I69768126"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Najeeb Shah","raw_affiliation_strings":["Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, HU3 2JZ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, HU3 2JZ, UK","institution_ids":["https://openalex.org/I191240316","https://openalex.org/I69768126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062170233","display_name":"Thozhukat Sathyapalan","orcid":"https://orcid.org/0000-0003-3544-2231","observed_orcids":["https://orcid.org/0000-0003-3544-2231"]},"institutions":[{"id":"https://openalex.org/I191240316","display_name":"University of Hull","ror":"https://ror.org/04nkhwh30","country_code":"GB","type":"education","lineage":["https://openalex.org/I191240316"]},{"id":"https://openalex.org/I69768126","display_name":"Hull York Medical School","ror":"https://ror.org/0003e4m70","country_code":"GB","type":"education","lineage":["https://openalex.org/I69768126"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Thozhukat Sathyapalan","raw_affiliation_strings":["Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, HU3 2JZ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, HU3 2JZ, UK","institution_ids":["https://openalex.org/I191240316","https://openalex.org/I69768126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032412684","display_name":"Muhammed A. Majeed","orcid":"https://orcid.org/0000-0002-1690-7470","observed_orcids":["https://orcid.org/0000-0002-1690-7470"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Muhammed Majeed","raw_affiliation_strings":["Sabinsa Corporation, East Windsor, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sabinsa Corporation, East Windsor, NJ, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105411377","display_name":"Alexander Nikolaevich Orekhov","orcid":"https://orcid.org/0000-0002-3318-4681","observed_orcids":["https://orcid.org/0000-0002-3318-4681"]},"institutions":[{"id":"https://openalex.org/I4210131054","display_name":"Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences","ror":"https://ror.org/03jmc9t23","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210131054"]},{"id":"https://openalex.org/I4210145101","display_name":"Research Institute of Human Morphology","ror":"https://ror.org/042k8ng80","country_code":"RU","type":"nonprofit","lineage":["https://openalex.org/I4210145101"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexander N. Orekhov","raw_affiliation_strings":["Institute of Human Morphology, 3 Tsyurupa Street, 117418, Moscow, Russia","Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Human Morphology, 3 Tsyurupa Street, 117418, Moscow, Russia","institution_ids":["https://openalex.org/I4210145101"]},{"raw_affiliation_string":"Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315, Moscow, Russia","institution_ids":["https://openalex.org/I4210131054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054750006","display_name":"Tannaz Jamialahmadi","orcid":"https://orcid.org/0000-0001-9521-3153","observed_orcids":["https://orcid.org/0000-0001-9521-3153"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Tannaz Jamialahmadi","raw_affiliation_strings":["Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036163332","display_name":"Amirhossein Sahebkar","orcid":"https://orcid.org/0000-0002-8656-1444","observed_orcids":["https://orcid.org/0000-0002-8656-1444","https://orcid.org/0000-0003-1747-8353"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]},{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU","IR"],"is_corresponding":true,"raw_author_name":"Amirhossein Sahebkar","raw_affiliation_strings":["Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir","Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir","School of Medicine, The University of Western Australia, Perth, Australia. sahebkara@mums.ac.ir","School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir","Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran"],"raw_orcid":"https://orcid.org/0000-0002-8656-1444","affiliations":[{"raw_affiliation_string":"Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir","institution_ids":["https://openalex.org/I165560825"]},{"raw_affiliation_string":"Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir","institution_ids":["https://openalex.org/I165560825"]},{"raw_affiliation_string":"School of Medicine, The University of Western Australia, Perth, Australia. sahebkara@mums.ac.ir","institution_ids":["https://openalex.org/I177877127"]},{"raw_affiliation_string":"School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir","institution_ids":["https://openalex.org/I165560825"]},{"raw_affiliation_string":"Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5036163332"],"corresponding_institution_ids":["https://openalex.org/I165560825","https://openalex.org/I177877127"],"apc_list":{"value":2780,"currency":"USD","value_usd":2780},"apc_paid":null,"fwci":0.3615,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.29527027,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"29","issue":"11","first_page":"3124","last_page":"3133"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.053199999034404755,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.996999979019165},{"id":"https://openalex.org/keywords/polycystic-ovary-syndrome","display_name":"polycystic ovary syndrome","score":1.0},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7979999780654907},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.75},{"id":"https://openalex.org/keywords/insulin-levels","display_name":"insulin levels","score":0.7580000162124634},{"id":"https://openalex.org/keywords/homa-ir","display_name":"HOMA-IR","score":0.9580000042915344},{"id":"https://openalex.org/keywords/lipid-parameters","display_name":"lipid parameters","score":0.8009999990463257},{"id":"https://openalex.org/keywords/hyperandrogenism","display_name":"hyperandrogenism","score":0.7540000081062317},{"id":"https://openalex.org/keywords/anti-inflammatory-phytochemicals","display_name":"anti-inflammatory phytochemicals","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C3018442814","wikidata":"https://www.wikidata.org/wiki/Q500816","display_name":"Polycystic ovary","level":4,"score":0.8634843826293945},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.790955126285553},{"id":"https://openalex.org/C2780186808","wikidata":"https://www.wikidata.org/wiki/Q10529545","display_name":"Hyperandrogenism","level":5,"score":0.7437318563461304},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6803696751594543},{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.6741552352905273},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.6676353812217712},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6026427149772644},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.5499805212020874},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5492914319038391},{"id":"https://openalex.org/C2776652674","wikidata":"https://www.wikidata.org/wiki/Q273924","display_name":"Glycemic index","level":4,"score":0.4831227958202362},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4770728349685669},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.46484771370887756},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.3625807762145996},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.16981744766235352},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.16239339113235474}],"mesh":[{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003474","descriptor_name":"Curcumin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011085","descriptor_name":"Polycystic Ovary Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017588","descriptor_name":"Hyperandrogenism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s43032-021-00761-6","doi":"https://doi.org/10.1007/s43032-021-00761-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s43032-021-00761-6","pdf_url":null,"source":{"id":"https://openalex.org/S68157034","display_name":"Reproductive Sciences","issn_l":"1933-7191","issn":["1933-7191","1933-7205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive Sciences","raw_type":"journal-article"},{"id":"pmid:34655047","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34655047","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive sciences (Thousand Oaks, Calif.)","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/f7cff063-fc7c-46fe-b3d3-5fdc968fc29d","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/f7cff063-fc7c-46fe-b3d3-5fdc968fc29d","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Simental-Mend\u00eda, L E, Shah, N, Sathyapalan, T, Majeed, M, Orekhov, A N, Jamialahmadi, T & Sahebkar, A 2022, 'Effect of Curcumin on Glycaemic and Lipid Parameters in Polycystic Ovary Syndrome : A Systematic Review and Meta-Analysis of Randomized Controlled Trials', Reproductive Sciences, vol. 29, no. 11, pp. 3124-3133. https://doi.org/10.1007/s43032-021-00761-6","raw_type":"info:eu-repo/semantics/review"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W296450459","https://openalex.org/W1515708729","https://openalex.org/W1537972189","https://openalex.org/W1572968453","https://openalex.org/W1598602811","https://openalex.org/W1944972564","https://openalex.org/W2015778467","https://openalex.org/W2021923144","https://openalex.org/W2048307543","https://openalex.org/W2056399290","https://openalex.org/W2058294720","https://openalex.org/W2063485400","https://openalex.org/W2063853955","https://openalex.org/W2073365457","https://openalex.org/W2085308984","https://openalex.org/W2093049350","https://openalex.org/W2108067228","https://openalex.org/W2131357228","https://openalex.org/W2133783450","https://openalex.org/W2136160261","https://openalex.org/W2139915659","https://openalex.org/W2153353583","https://openalex.org/W2156098321","https://openalex.org/W2186218348","https://openalex.org/W2306848376","https://openalex.org/W2416427161","https://openalex.org/W2499178053","https://openalex.org/W2516002094","https://openalex.org/W2547036892","https://openalex.org/W2762357782","https://openalex.org/W2769765530","https://openalex.org/W2788954328","https://openalex.org/W2794412718","https://openalex.org/W2902106514","https://openalex.org/W2963200213","https://openalex.org/W2977196190","https://openalex.org/W2991792334","https://openalex.org/W3000023256","https://openalex.org/W3003490674","https://openalex.org/W3013178165","https://openalex.org/W3088559724","https://openalex.org/W3090320784","https://openalex.org/W3093833227","https://openalex.org/W3153257769","https://openalex.org/W4256605237","https://openalex.org/W7214890307"],"related_works":["https://openalex.org/W3131374499","https://openalex.org/W4210331638","https://openalex.org/W3200894629","https://openalex.org/W4307446359","https://openalex.org/W3003490674","https://openalex.org/W4406336685","https://openalex.org/W4384469597","https://openalex.org/W4386403332","https://openalex.org/W4408245566","https://openalex.org/W2977196190"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-10-25T00:00:00"}