{"id":"https://openalex.org/W3207170434","doi":"https://doi.org/10.1016/j.jphotobiol.2021.112333","title":"Titaniumdioxide mediated sonophotodynamic therapy against prostate cancer","display_name":"Titaniumdioxide mediated sonophotodynamic therapy against prostate cancer","publication_year":2021,"publication_date":"2021-10-12","ids":{"openalex":"https://openalex.org/W3207170434","doi":"https://doi.org/10.1016/j.jphotobiol.2021.112333","mag":"3207170434","pmid":"https://pubmed.ncbi.nlm.nih.gov/34688979"},"language":"en","primary_location":{"id":"doi:10.1016/j.jphotobiol.2021.112333","doi":"https://doi.org/10.1016/j.jphotobiol.2021.112333","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jphotobiol.2021.112333","pdf_url":null,"source":{"id":"https://openalex.org/S148303206","display_name":"Journal of Photochemistry and Photobiology B Biology","issn_l":"1011-1344","issn":["1011-1344","1873-2682"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Photochemistry and Photobiology B: Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010929802","display_name":"Mehran Aksel","orcid":"https://orcid.org/0000-0002-3942-2257","observed_orcids":["https://orcid.org/0000-0002-3942-2257"]},"institutions":[{"id":"https://openalex.org/I76806599","display_name":"Adnan Menderes University","ror":"https://ror.org/03n7yzv56","country_code":"TR","type":"education","lineage":["https://openalex.org/I76806599"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mehran Aksel","raw_affiliation_strings":["Department of Biophysics, Aydin Adnan Menderes University, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biophysics, Aydin Adnan Menderes University, Turkey","institution_ids":["https://openalex.org/I76806599"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038235238","display_name":"\u00d6mer Kesmez","orcid":"https://orcid.org/0000-0003-0107-8558","observed_orcids":["https://orcid.org/0000-0003-0107-8558"]},"institutions":[{"id":"https://openalex.org/I197907453","display_name":"Akdeniz University","ror":"https://ror.org/01m59r132","country_code":"TR","type":"education","lineage":["https://openalex.org/I197907453"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u00d6mer Kesmez","raw_affiliation_strings":["Akdeniz University, Faculty of Science, Department of Chemistry, 07058 Antalya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Akdeniz University, Faculty of Science, Department of Chemistry, 07058 Antalya, Turkey","institution_ids":["https://openalex.org/I197907453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069425549","display_name":"Adem Yava\u015f","orcid":"https://orcid.org/0000-0003-3506-4306","observed_orcids":["https://orcid.org/0000-0003-3506-4306"]},"institutions":[{"id":"https://openalex.org/I76806599","display_name":"Adnan Menderes University","ror":"https://ror.org/03n7yzv56","country_code":"TR","type":"education","lineage":["https://openalex.org/I76806599"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Adem Yava\u015f","raw_affiliation_strings":["Agricultural Biotechnology and Food Safety Research and Application Center, Aydin Adnan Menderes University, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Biotechnology and Food Safety Research and Application Center, Aydin Adnan Menderes University, Turkey","institution_ids":["https://openalex.org/I76806599"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006781949","display_name":"Mehmet Bilgin","orcid":"https://orcid.org/0000-0003-0754-0854","observed_orcids":["https://orcid.org/0000-0003-0754-0854"]},"institutions":[{"id":"https://openalex.org/I76806599","display_name":"Adnan Menderes University","ror":"https://ror.org/03n7yzv56","country_code":"TR","type":"education","lineage":["https://openalex.org/I76806599"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Mehmet Din\u00e7er Bilgin","raw_affiliation_strings":["Department of Biophysics, Aydin Adnan Menderes University, Turkey. Electronic address: mdbilgin@adu.edu.tr","Department of Biophysics, Aydin Adnan Menderes University, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biophysics, Aydin Adnan Menderes University, Turkey. Electronic address: mdbilgin@adu.edu.tr","institution_ids":["https://openalex.org/I76806599"]},{"raw_affiliation_string":"Department of Biophysics, Aydin Adnan Menderes University, Turkey","institution_ids":["https://openalex.org/I76806599"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5006781949"],"corresponding_institution_ids":["https://openalex.org/I76806599"],"apc_list":{"value":3100,"currency":"USD","value_usd":3100},"apc_paid":null,"fwci":2.4934,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.91688292,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"225","issue":null,"first_page":"112333","last_page":"112333"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.7235999703407288,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.7235999703407288,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.27559998631477356,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/titanium-dioxide-nanoparticles","display_name":"titanium dioxide nanoparticles","score":0.8410000205039978},{"id":"https://openalex.org/keywords/sonodynamic-therapy","display_name":"sonodynamic therapy","score":0.9020000100135803},{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"photodynamic therapy","score":1.0},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pc-3-cells","display_name":"PC-3 cells","score":0.984000027179718},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9449999928474426},{"id":"https://openalex.org/keywords/caspase-3","display_name":"caspase-3","score":0.8550000190734863},{"id":"https://openalex.org/keywords/caspase-8","display_name":"caspase-8","score":0.9120000004768372},{"id":"https://openalex.org/keywords/caspase-9","display_name":"caspase-9","score":0.9900000095367432},{"id":"https://openalex.org/keywords/bax","display_name":"Bax","score":0.7760000228881836},{"id":"https://openalex.org/keywords/poly-adp-ribose-polymerase","display_name":"poly(ADP-ribose) polymerase","score":0.6359999775886536},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7039999961853027},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.6700000166893005},{"id":"https://openalex.org/keywords/light-irradiation","display_name":"light irradiation","score":0.7599999904632568}],"concepts":[{"id":"https://openalex.org/C2778448707","wikidata":"https://www.wikidata.org/wiki/Q7562147","display_name":"Sonodynamic therapy","level":3,"score":0.8040450811386108},{"id":"https://openalex.org/C2775934118","wikidata":"https://www.wikidata.org/wiki/Q424169","display_name":"Propidium iodide","level":4,"score":0.7160469889640808},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.6823538541793823},{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.681104838848114},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6369509696960449},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.6008989214897156},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5305571556091309},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4572112560272217},{"id":"https://openalex.org/C12519072","wikidata":"https://www.wikidata.org/wiki/Q14914370","display_name":"Caspase 3","level":4,"score":0.4470929801464081},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4274793565273285},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42089757323265076},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.4199668765068054},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4173927903175354},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3534218668937683},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.2626931071281433},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2515539526939392},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1222856342792511},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010778","descriptor_name":"Photochemotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014025","descriptor_name":"Titanium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014025","descriptor_name":"Titanium","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014464","descriptor_name":"Ultrasonic Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jphotobiol.2021.112333","doi":"https://doi.org/10.1016/j.jphotobiol.2021.112333","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jphotobiol.2021.112333","pdf_url":null,"source":{"id":"https://openalex.org/S148303206","display_name":"Journal of Photochemistry and Photobiology B Biology","issn_l":"1011-1344","issn":["1011-1344","1873-2682"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Photochemistry and Photobiology B: Biology","raw_type":"journal-article"},{"id":"pmid:34688979","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34688979","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of photochemistry and photobiology. B, Biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6940599414","display_name":null,"funder_award_id":"ADU-TPF-20002","funder_id":"https://openalex.org/F4320321404","funder_display_name":"Adnan Menderes \u00dcniversitesi"}],"funders":[{"id":"https://openalex.org/F4320321404","display_name":"Adnan Menderes \u00dcniversitesi","ror":"https://ror.org/03n7yzv56"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1965357443","https://openalex.org/W1983591971","https://openalex.org/W1991092869","https://openalex.org/W2001429551","https://openalex.org/W2002104944","https://openalex.org/W2008319585","https://openalex.org/W2009744235","https://openalex.org/W2016540525","https://openalex.org/W2025379905","https://openalex.org/W2029926338","https://openalex.org/W2030270605","https://openalex.org/W2030713573","https://openalex.org/W2034133622","https://openalex.org/W2037642785","https://openalex.org/W2040149066","https://openalex.org/W2042593374","https://openalex.org/W2047985404","https://openalex.org/W2051944278","https://openalex.org/W2062960163","https://openalex.org/W2087616100","https://openalex.org/W2088487041","https://openalex.org/W2095268361","https://openalex.org/W2103662174","https://openalex.org/W2106448851","https://openalex.org/W2121654906","https://openalex.org/W2132089826","https://openalex.org/W2142001117","https://openalex.org/W2150014101","https://openalex.org/W2293724296","https://openalex.org/W2308048971","https://openalex.org/W2403760074","https://openalex.org/W2524995354","https://openalex.org/W2585948158","https://openalex.org/W2758017374","https://openalex.org/W2766708256","https://openalex.org/W2783832526","https://openalex.org/W2796540999","https://openalex.org/W2807067922","https://openalex.org/W2886849948","https://openalex.org/W2951509935","https://openalex.org/W2996641097","https://openalex.org/W2999417355","https://openalex.org/W3008096634","https://openalex.org/W3039047336","https://openalex.org/W3103277581","https://openalex.org/W3120735659","https://openalex.org/W3133924569","https://openalex.org/W4244008746","https://openalex.org/W6679263981"],"related_works":["https://openalex.org/W2585948158","https://openalex.org/W7138871710","https://openalex.org/W3049646357","https://openalex.org/W2001429551","https://openalex.org/W3039047336","https://openalex.org/W4320035124","https://openalex.org/W3034500078","https://openalex.org/W7154345874","https://openalex.org/W2894538772","https://openalex.org/W4410370617"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-10-25T00:00:00"}