{"id":"https://openalex.org/W3206922157","doi":"https://doi.org/10.1016/j.jtho.2021.08.610","title":"P59.21 Impact of Reflex Testing on Pathology Based Molecular Testing in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC)","display_name":"P59.21 Impact of Reflex Testing on Pathology Based Molecular Testing in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC)","publication_year":2021,"publication_date":"2021-10-01","ids":{"openalex":"https://openalex.org/W3206922157","doi":"https://doi.org/10.1016/j.jtho.2021.08.610","mag":"3206922157"},"language":"en","primary_location":{"id":"doi:10.1016/j.jtho.2021.08.610","doi":"https://doi.org/10.1016/j.jtho.2021.08.610","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtho.2021.08.610","pdf_url":null,"source":{"id":"https://openalex.org/S90745127","display_name":"Journal of Thoracic Oncology","issn_l":"1556-0864","issn":["1556-0864","1556-1380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.jtho.2021.08.610","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022346171","display_name":"Melina Elpi Marmarelis","orcid":"https://orcid.org/0000-0003-2187-3583","observed_orcids":["https://orcid.org/0000-0003-2187-3583"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Marmarelis","raw_affiliation_strings":["Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082385497","display_name":"Abigail T. Berman","orcid":"https://orcid.org/0000-0002-9969-3462","observed_orcids":["https://orcid.org/0000-0002-9969-3462"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Berman","raw_affiliation_strings":["Department of Radiation Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037771406","display_name":"Dylan G. Scholes","orcid":"https://orcid.org/0000-0002-5800-259X","observed_orcids":["https://orcid.org/0000-0002-5800-259X"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Scholes","raw_affiliation_strings":["Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031689520","display_name":"Jeffrey C. Thompson","orcid":"https://orcid.org/0000-0001-5734-0004","observed_orcids":["https://orcid.org/0000-0001-5734-0004"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Thompson","raw_affiliation_strings":["Pulmonary and Critical Care Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary and Critical Care Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017346791","display_name":"Abigail G. Doucette","orcid":"https://orcid.org/0000-0002-6646-433X","observed_orcids":["https://orcid.org/0000-0002-6646-433X"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Doucette","raw_affiliation_strings":["Thoracic Oncology Translational Center of Excellence, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Oncology Translational Center of Excellence, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069741414","display_name":"Peter Edward Gabriel","orcid":"https://orcid.org/0000-0002-3772-9669","observed_orcids":["https://orcid.org/0000-0002-3772-9669"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Gabriel","raw_affiliation_strings":["Department of Radiation Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062034160","display_name":"Joshua Michael Bauml","orcid":"https://orcid.org/0000-0003-4193-841X","observed_orcids":["https://orcid.org/0000-0003-4193-841X"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Bauml","raw_affiliation_strings":["Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100679859","display_name":"Aditi Puri Singh","orcid":"https://orcid.org/0000-0002-2063-6407","observed_orcids":["https://orcid.org/0000-0002-2063-6407"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Singh","raw_affiliation_strings":["Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110382646","display_name":"Roger B. Cohen","orcid":"https://orcid.org/0009-0004-7423-2653","observed_orcids":["https://orcid.org/0009-0004-7423-2653"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Cohen","raw_affiliation_strings":["Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054533558","display_name":"Leslie A. Litzky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Litzky","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015767949","display_name":"Cindy M. McGrath","orcid":"https://orcid.org/0000-0001-5079-0256","observed_orcids":["https://orcid.org/0000-0001-5079-0256"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Mcgrath","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028140714","display_name":"Michael D. Feldman","orcid":"https://orcid.org/0000-0002-6661-4940","observed_orcids":["https://orcid.org/0000-0002-6661-4940"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Feldman","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090256464","display_name":"Corey Jay Langer","orcid":"https://orcid.org/0000-0002-8483-6811","observed_orcids":["https://orcid.org/0000-0002-8483-6811"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Langer","raw_affiliation_strings":["Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029750461","display_name":"Erica L. Carpenter","orcid":"https://orcid.org/0000-0002-0735-3605","observed_orcids":["https://orcid.org/0000-0002-0735-3605"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. Carpenter","raw_affiliation_strings":["Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056098854","display_name":"Charu Aggarwal","orcid":"https://orcid.org/0000-0002-3181-9460","observed_orcids":["https://orcid.org/0000-0002-3181-9460"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Aggarwal","raw_affiliation_strings":["Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine - Hematology Oncology, University of Pennsylvania, Philadelphia/PA/US","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":{"value":2800,"currency":"USD","value_usd":2800},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"10","first_page":"S1157","last_page":"S1157"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reflex-testing","display_name":"reflex testing","score":0.7940000295639038},{"id":"https://openalex.org/keywords/non-squamous-non-small-cell-lung-cancer","display_name":"non-squamous non-small cell lung cancer","score":0.9160000085830688},{"id":"https://openalex.org/keywords/comprehensive-molecular-profiling","display_name":"comprehensive molecular profiling","score":0.7160000205039978},{"id":"https://openalex.org/keywords/next-generation-sequencing","display_name":"next-generation sequencing","score":0.9210000038146973},{"id":"https://openalex.org/keywords/pathology-review","display_name":"pathology review","score":0.5950000286102295},{"id":"https://openalex.org/keywords/metastatic-lung-cancer","display_name":"metastatic lung cancer","score":0.8100000023841858}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8923195600509644},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6057479977607727},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5227418541908264},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5051503777503967},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.4900761842727661},{"id":"https://openalex.org/C74092355","wikidata":"https://www.wikidata.org/wiki/Q1056943","display_name":"Molecular pathology","level":3,"score":0.4848083555698395},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4272041916847229},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3816570043563843},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.27732425928115845},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2346857488155365},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jtho.2021.08.610","doi":"https://doi.org/10.1016/j.jtho.2021.08.610","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtho.2021.08.610","pdf_url":null,"source":{"id":"https://openalex.org/S90745127","display_name":"Journal of Thoracic Oncology","issn_l":"1556-0864","issn":["1556-0864","1556-1380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Oncology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jtho.2021.08.610","doi":"https://doi.org/10.1016/j.jtho.2021.08.610","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtho.2021.08.610","pdf_url":null,"source":{"id":"https://openalex.org/S90745127","display_name":"Journal of Thoracic Oncology","issn_l":"1556-0864","issn":["1556-0864","1556-1380"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4286294239","https://openalex.org/W4392697778","https://openalex.org/W7221619098","https://openalex.org/W4403922024","https://openalex.org/W4303945944","https://openalex.org/W4394878948","https://openalex.org/W4392101541","https://openalex.org/W4400108835","https://openalex.org/W4400452795","https://openalex.org/W2947524967"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2021-10-25T00:00:00"}