{"id":"https://openalex.org/W3206662670","doi":"https://doi.org/10.1016/j.jtcms.2021.10.003","title":"Rapid chemome profiling of Artemisia capillaris Thunb. using direct infusion-mass spectrometry","display_name":"Rapid chemome profiling of Artemisia capillaris Thunb. using direct infusion-mass spectrometry","publication_year":2021,"publication_date":"2021-10-01","ids":{"openalex":"https://openalex.org/W3206662670","doi":"https://doi.org/10.1016/j.jtcms.2021.10.003","mag":"3206662670"},"language":"en","primary_location":{"id":"doi:10.1016/j.jtcms.2021.10.003","doi":"https://doi.org/10.1016/j.jtcms.2021.10.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtcms.2021.10.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2095754821000697/pdf","source":{"id":"https://openalex.org/S2765057931","display_name":"Journal of Traditional Chinese Medical Sciences","issn_l":"2095-7548","issn":["2095-7548","2589-0395"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Traditional Chinese Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2095754821000697/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100378303","display_name":"Wenjing Liu","orcid":"https://orcid.org/0000-0003-0441-8634","observed_orcids":["https://orcid.org/0000-0003-0441-8634"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenjing Liu","raw_affiliation_strings":["School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101804091","display_name":"Libo Cao","orcid":"https://orcid.org/0000-0002-2823-4971","observed_orcids":["https://orcid.org/0000-0002-2823-4971"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Libo Cao","raw_affiliation_strings":["School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109209015","display_name":"Jinru Jia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinru Jia","raw_affiliation_strings":["School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100784705","display_name":"Han Li","orcid":"https://orcid.org/0009-0002-6719-3401","observed_orcids":["https://orcid.org/0009-0002-6719-3401"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Han Li","raw_affiliation_strings":["School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100318325","display_name":"W\u011bi Li","orcid":"https://orcid.org/0000-0002-9522-4474","observed_orcids":["https://orcid.org/0000-0002-9522-4474","https://orcid.org/0000-0003-4136-3409","https://orcid.org/0009-0009-9141-6389"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Li","raw_affiliation_strings":["School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100361689","display_name":"Jun Li","orcid":"https://orcid.org/0000-0001-8243-5267","observed_orcids":["https://orcid.org/0000-0001-8243-5267"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Li","raw_affiliation_strings":["School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China","institution_ids":["https://openalex.org/I17747738"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002092115","display_name":"Yuelin Song","orcid":"https://orcid.org/0000-0001-9431-6257","observed_orcids":["https://orcid.org/0000-0001-9431-6257"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yuelin Song","raw_affiliation_strings":["School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China","institution_ids":["https://openalex.org/I17747738"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5002092115"],"corresponding_institution_ids":["https://openalex.org/I17747738"],"apc_list":{"value":1400,"currency":"USD","value_usd":1400},"apc_paid":{"value":1400,"currency":"USD","value_usd":1400},"fwci":0.2689,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.58554624,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"8","issue":"4","first_page":"327","last_page":"335"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.8730000257492065,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.8730000257492065,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.10999999940395355,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artemisia-capillaris","display_name":"Artemisia capillaris","score":1.0},{"id":"https://openalex.org/keywords/direct-infusion-mass-spectrometry","display_name":"direct infusion mass spectrometry","score":0.9229999780654907},{"id":"https://openalex.org/keywords/data-independent-acquisition","display_name":"data-independent acquisition","score":0.8730000257492065},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":1.0},{"id":"https://openalex.org/keywords/chemical-composition","display_name":"chemical composition","score":0.6100000143051147},{"id":"https://openalex.org/keywords/traditional-chinese-medicine","display_name":"traditional Chinese medicine","score":0.8259999752044678},{"id":"https://openalex.org/keywords/high-throughput-analysis","display_name":"high-throughput analysis","score":0.7170000076293945},{"id":"https://openalex.org/keywords/electrospray-ionization","display_name":"electrospray ionization","score":0.7329999804496765}],"concepts":[{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.6651601791381836},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5943303108215332},{"id":"https://openalex.org/C31827203","wikidata":"https://www.wikidata.org/wiki/Q874296","display_name":"Tandem mass spectrometry","level":3,"score":0.5930553674697876},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5655133724212646},{"id":"https://openalex.org/C40684141","wikidata":"https://www.wikidata.org/wiki/Q902061","display_name":"Electrospray ionization","level":3,"score":0.5625144839286804},{"id":"https://openalex.org/C2777402617","wikidata":"https://www.wikidata.org/wiki/Q424931","display_name":"Quinic acid","level":2,"score":0.41927915811538696},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09918203949928284}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jtcms.2021.10.003","doi":"https://doi.org/10.1016/j.jtcms.2021.10.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtcms.2021.10.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2095754821000697/pdf","source":{"id":"https://openalex.org/S2765057931","display_name":"Journal of Traditional Chinese Medical Sciences","issn_l":"2095-7548","issn":["2095-7548","2589-0395"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Traditional Chinese Medical Sciences","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:92cb2293ceab4af38101b46b7a7b0b43","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/92cb2293ceab4af38101b46b7a7b0b43","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Traditional Chinese Medical Sciences, Vol 8, Iss 4, Pp 327-335 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jtcms.2021.10.003","doi":"https://doi.org/10.1016/j.jtcms.2021.10.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtcms.2021.10.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2095754821000697/pdf","source":{"id":"https://openalex.org/S2765057931","display_name":"Journal of Traditional Chinese Medical Sciences","issn_l":"2095-7548","issn":["2095-7548","2589-0395"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Traditional Chinese Medical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2005618","display_name":null,"funder_award_id":"81773875","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3242130388","display_name":null,"funder_award_id":"81973444","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4469669277","display_name":null,"funder_award_id":"2018YFC1707300","funder_id":"https://openalex.org/F4320336026","funder_display_name":"National Key Research and Development Program of China Stem Cell and Translational Research"},{"id":"https://openalex.org/G5497869902","display_name":null,"funder_award_id":"2018YFC1707300","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320336026","display_name":"National Key Research and Development Program of China Stem Cell and Translational Research","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3206662670.pdf","grobid_xml":"https://content.openalex.org/works/W3206662670.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1971979906","https://openalex.org/W2004370342","https://openalex.org/W2036534397","https://openalex.org/W2051852436","https://openalex.org/W2079738393","https://openalex.org/W2103213754","https://openalex.org/W2105801844","https://openalex.org/W2208677855","https://openalex.org/W2325701587","https://openalex.org/W2359654824","https://openalex.org/W2511885262","https://openalex.org/W2557330963","https://openalex.org/W2775545862","https://openalex.org/W2799606660","https://openalex.org/W2884228343","https://openalex.org/W2896817976","https://openalex.org/W2898468989","https://openalex.org/W2935821985","https://openalex.org/W2946917215","https://openalex.org/W2971361209","https://openalex.org/W3024553551","https://openalex.org/W3025111507","https://openalex.org/W3034387601","https://openalex.org/W3082246592","https://openalex.org/W3083314342","https://openalex.org/W3084100977","https://openalex.org/W3084174246","https://openalex.org/W3092122033","https://openalex.org/W3136839246","https://openalex.org/W3162549472","https://openalex.org/W3182763872","https://openalex.org/W3185835344","https://openalex.org/W4249685777","https://openalex.org/W4285719527","https://openalex.org/W6831520842"],"related_works":["https://openalex.org/W3162549472","https://openalex.org/W2070479100","https://openalex.org/W2263508648","https://openalex.org/W3165657783","https://openalex.org/W2376798334","https://openalex.org/W2410979116","https://openalex.org/W4410522888","https://openalex.org/W3024553551","https://openalex.org/W3185835344","https://openalex.org/W1977346815"],"abstract_inverted_index":{"As":[0],"one":[1],"of":[2,13,47,101,152,236,243,266],"the":[3,11,37,43,54,68,81,89,99,107,127,153,170,176,180,195,229,234],"most":[4],"popular":[5],"traditional":[6],"Chinese":[7],"medicines":[8],"(TCMs)":[9],"for":[10,42,115,158,262],"treatment":[12],"various":[14],"liver":[15],"diseases,":[16],"virgate":[17],"wormwood":[18],"herb":[19],"(Artemisia":[20],"capillaris":[21,160,164,245],"Thunb.)":[22],"has":[23,32,233],"a":[24,121],"long":[25],"application":[26,100],"history":[27],"in":[28],"TCM":[29],"practices.":[30],"It":[31],"been":[33],"well":[34,184],"established":[35],"that":[36],"chemical":[38,154,218,263],"composition":[39,155],"is":[40,144],"responsible":[41],"pronounced":[44],"therapeutic":[45],"spectrum":[46,114],"A.":[48,159,163,244],"capillaris.":[49],"Although":[50],"they":[51],"are":[52],"comprehensive,":[53],"time-intensive":[55],"liquid":[56],"chromatography":[57],"coupled":[58],"to":[59,84,98,111,174,216,269],"tandem":[60],"mass":[61,90],"spectrometry":[62],"(LC\u2013MS/MS)":[63],"assays":[64],"cannot":[65],"fully":[66],"satisfy":[67],"analytical":[69],"measurement":[70,142],"workload":[71],"from":[72,194],"many":[73],"test":[74],"samples.":[75],"Direct":[76],"infusion-MS/MS":[77],"(DI\u2013MS/MS)":[78],"may":[79],"be":[80,258],"optimal":[82],"choice":[83,261],"achieve":[85],"high-throughput":[86,272],"analysis":[87],"if":[88],"spectrometer":[91],"can":[92,257],"universally":[93],"record":[94],"MS2":[95,113],"spectra.":[96],"According":[97],"gas":[102],"phase":[103],"ion":[104,130,134],"fractionation":[105],"concept,":[106],"MS/MSALL":[108,177],"program":[109],"enables":[110],"gain":[112],"each":[116],"nominal":[117],"m/z":[118],"value":[119],"with":[120,136,228],"data-independent":[122],"acquisition":[123],"algorithm":[124],"via":[125],"segmenting":[126],"entire":[128],"MS1":[129],"cohort":[131],"into":[132,169],"sequential":[133],"pieces":[135],"1":[137],"Da":[138],"width,":[139],"when":[140],"sufficient":[141],"time":[143],"allowed":[145],"by":[146,252],"DI":[147],"approach.":[148],"Here,":[149],"rapid":[150],"clarification":[151],"was":[156,166,183,247],"attempted":[157],"using":[161],"DI\u2013MS/MSALL.":[162],"extract":[165,246],"imported":[167],"directly":[168],"electrospray":[171],"ionization":[172],"interface":[173],"obtain":[175],"measurement.":[178],"After":[179],"MS1-MS2":[181],"dataset":[182],"organized,":[185],"we":[186],"focused":[187],"on":[188],"structural":[189],"characterization":[190,265],"through":[191],"retrieving":[192],"information":[193],"available":[196],"databases":[197],"and":[198,212,239,254],"literature.":[199],"Twenty-six":[200],"compounds":[201,214],"were":[202,224],"found,":[203],"including":[204],"12":[205],"caffeoyl":[206],"quinic":[207],"acid":[208],"derivatives,":[209],"7":[210,213],"flavonoids,":[211],"belonging":[215],"other":[217],"families.":[219],"Among":[220],"them,":[221],"24":[222],"ones":[223],"structurally":[225],"identified.":[226],"Compared":[227],"LC\u2013MS/MS":[230],"technique,":[231],"DI\u2013MS/MSALL":[232],"advantages":[235],"low-costing,":[237],"solvent-saving,":[238],"time-saving.":[240],"Chemical":[241],"profiling":[242],"accomplished":[248],"within":[249],"5":[250],"min":[251],"DI\u2013MS/MSALL,":[253],"this":[255],"technique":[256],"an":[259],"alternative":[260],"profile":[264],"TCMs":[267],"due":[268],"its":[270],"extraordinary":[271],"advantage.":[273]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-10-25T00:00:00"}