{"id":"https://openalex.org/W3206599239","doi":"https://doi.org/10.26599/jnr.2021.9040010","title":"Improved survival in amyotrophic lateral sclerosis patients following autologous bone marrow mononuclear cell therapy: a long term 10-year retrospective study","display_name":"Improved survival in amyotrophic lateral sclerosis patients following autologous bone marrow mononuclear cell therapy: a long term 10-year retrospective study","publication_year":2021,"publication_date":"2021-06-01","ids":{"openalex":"https://openalex.org/W3206599239","doi":"https://doi.org/10.26599/jnr.2021.9040010","mag":"3206599239"},"language":"en","primary_location":{"id":"doi:10.26599/jnr.2021.9040010","doi":"https://doi.org/10.26599/jnr.2021.9040010","is_oa":true,"landing_page_url":"https://doi.org/10.26599/jnr.2021.9040010","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2324242622000493/pdf","source":{"id":"https://openalex.org/S4210239029","display_name":"Journal of Neurorestoratology","issn_l":"2324-2426","issn":["2324-2426"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurorestoratology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2324242622000493/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100621625","display_name":"Alok Kumar Sharma","orcid":"https://orcid.org/0000-0002-6645-3227","observed_orcids":["https://orcid.org/0000-0002-6645-3227","https://orcid.org/0000-0002-3349-3580"]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Alok Sharma","raw_affiliation_strings":["Department of Medical Services and Clinical Research, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Services and Clinical Research, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086552719","display_name":"Hemangi M Sane","orcid":"https://orcid.org/0000-0002-4871-338X","observed_orcids":["https://orcid.org/0000-0002-4871-338X"]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Hemangi Sane","raw_affiliation_strings":["Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020503787","display_name":"Amruta Paranjape","orcid":"https://orcid.org/0000-0003-2099-7648","observed_orcids":["https://orcid.org/0000-0003-2099-7648"]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Amruta Paranjape","raw_affiliation_strings":["Department of Neurorehabilitation, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurorehabilitation, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]},{"raw_affiliation_string":"Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017815666","display_name":"Ritu Varghese","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ritu Varghese","raw_affiliation_strings":["Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081171802","display_name":"Vivek Nair","orcid":"https://orcid.org/0000-0003-3218-5196","observed_orcids":["https://orcid.org/0000-0003-3218-5196"]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vivek Nair","raw_affiliation_strings":["Department of Neurorehabilitation, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurorehabilitation, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006338892","display_name":"Hema Biju","orcid":"https://orcid.org/0009-0005-0385-5068","observed_orcids":["https://orcid.org/0009-0005-0385-5068"]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Hema Biju","raw_affiliation_strings":["Department of Neurorehabilitation, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurorehabilitation, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112821972","display_name":"Dhanashree Sawant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Dhanashree Sawant","raw_affiliation_strings":["Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research and Development, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063125292","display_name":"Nandini Gokulchandran","orcid":"https://orcid.org/0000-0003-2195-7015","observed_orcids":["https://orcid.org/0000-0003-2195-7015"]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nandini Gokulchandran","raw_affiliation_strings":["Department of Medical Services and Clinical Research, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Services and Clinical Research, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070849020","display_name":"Prerna B. Badhe","orcid":"https://orcid.org/0000-0002-5982-4704","observed_orcids":["https://orcid.org/0000-0002-5982-4704"]},"institutions":[{"id":"https://openalex.org/I4210096296","display_name":"Neurogen Brain & Spine Institute","ror":"https://ror.org/00yjka566","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210096296"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prerna Badhe","raw_affiliation_strings":["Department of Regenerative Laboratory Services, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Regenerative Laboratory Services, NeuroGen Brain and Spine Institute, Navi Mumbai, 400706, Maharashtra, India","institution_ids":["https://openalex.org/I4210096296"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5020503787"],"corresponding_institution_ids":["https://openalex.org/I4210096296"],"apc_list":{"value":1700,"currency":"USD","value_usd":1700},"apc_paid":{"value":1700,"currency":"USD","value_usd":1700},"fwci":0.7954,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.69225796,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"9","issue":"2","first_page":"117","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":1.0},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.7379999756813049},{"id":"https://openalex.org/keywords/survival-time","display_name":"survival time","score":0.8019999861717224},{"id":"https://openalex.org/keywords/limb-onset","display_name":"limb onset","score":0.5550000071525574},{"id":"https://openalex.org/keywords/bulbar-onset","display_name":"bulbar onset","score":0.9980000257492065},{"id":"https://openalex.org/keywords/menopause","display_name":"menopause","score":0.6470000147819519},{"id":"https://openalex.org/keywords/andropause","display_name":"andropause","score":0.8209999799728394},{"id":"https://openalex.org/keywords/hormonal-status","display_name":"hormonal status","score":0.7559999823570251},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.8220000267028809},{"id":"https://openalex.org/keywords/long-term-treatment-efficacy","display_name":"long-term treatment efficacy","score":0.48500001430511475}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9079294204711914},{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.6693614721298218},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5274648666381836},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5175589919090271},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5093901753425598},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5035893321037292},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.496886283159256},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.4899267554283142},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4513697326183319},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.41628071665763855},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2154804766178131},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.26599/jnr.2021.9040010","doi":"https://doi.org/10.26599/jnr.2021.9040010","is_oa":true,"landing_page_url":"https://doi.org/10.26599/jnr.2021.9040010","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2324242622000493/pdf","source":{"id":"https://openalex.org/S4210239029","display_name":"Journal of Neurorestoratology","issn_l":"2324-2426","issn":["2324-2426"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurorestoratology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:786c31289a8246fcb47f0958dfd2408a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/786c31289a8246fcb47f0958dfd2408a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Neurorestoratology, Vol 9, Iss 2, Pp 117-136 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.26599/jnr.2021.9040010","doi":"https://doi.org/10.26599/jnr.2021.9040010","is_oa":true,"landing_page_url":"https://doi.org/10.26599/jnr.2021.9040010","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2324242622000493/pdf","source":{"id":"https://openalex.org/S4210239029","display_name":"Journal of Neurorestoratology","issn_l":"2324-2426","issn":["2324-2426"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurorestoratology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3206599239.pdf","grobid_xml":"https://content.openalex.org/works/W3206599239.grobid-xml"},"referenced_works_count":106,"referenced_works":["https://openalex.org/W18768637","https://openalex.org/W149137856","https://openalex.org/W262233206","https://openalex.org/W1566491090","https://openalex.org/W1598042935","https://openalex.org/W1599038895","https://openalex.org/W1622777525","https://openalex.org/W1894493322","https://openalex.org/W1964030946","https://openalex.org/W1968109664","https://openalex.org/W1968427639","https://openalex.org/W1969942100","https://openalex.org/W1970572671","https://openalex.org/W1971218073","https://openalex.org/W1972656994","https://openalex.org/W1975872544","https://openalex.org/W1976725490","https://openalex.org/W1978370369","https://openalex.org/W1980639550","https://openalex.org/W1980867773","https://openalex.org/W1981409516","https://openalex.org/W1987522740","https://openalex.org/W1994177774","https://openalex.org/W1996973828","https://openalex.org/W1998975866","https://openalex.org/W2013078581","https://openalex.org/W2018110972","https://openalex.org/W2020059513","https://openalex.org/W2020844167","https://openalex.org/W2023509574","https://openalex.org/W2028635283","https://openalex.org/W2032847865","https://openalex.org/W2034254855","https://openalex.org/W2034842853","https://openalex.org/W2036119801","https://openalex.org/W2038387222","https://openalex.org/W2045655578","https://openalex.org/W2045798092","https://openalex.org/W2049407128","https://openalex.org/W2057100984","https://openalex.org/W2058140531","https://openalex.org/W2061567079","https://openalex.org/W2063799957","https://openalex.org/W2063838755","https://openalex.org/W2064640860","https://openalex.org/W2064752834","https://openalex.org/W2064982871","https://openalex.org/W2066259320","https://openalex.org/W2066996015","https://openalex.org/W2067014198","https://openalex.org/W2067977709","https://openalex.org/W2069399162","https://openalex.org/W2072204165","https://openalex.org/W2073264699","https://openalex.org/W2073864172","https://openalex.org/W2083959138","https://openalex.org/W2095832155","https://openalex.org/W2096386031","https://openalex.org/W2097367691","https://openalex.org/W2101069762","https://openalex.org/W2102238895","https://openalex.org/W2106105150","https://openalex.org/W2114803648","https://openalex.org/W2115803656","https://openalex.org/W2119665388","https://openalex.org/W2120950413","https://openalex.org/W2121500739","https://openalex.org/W2122206229","https://openalex.org/W2122491860","https://openalex.org/W2123387289","https://openalex.org/W2126824828","https://openalex.org/W2128084057","https://openalex.org/W2128167427","https://openalex.org/W2128766634","https://openalex.org/W2138130369","https://openalex.org/W2139501951","https://openalex.org/W2141677575","https://openalex.org/W2144536780","https://openalex.org/W2147461659","https://openalex.org/W2150994376","https://openalex.org/W2155221045","https://openalex.org/W2155921007","https://openalex.org/W2157078177","https://openalex.org/W2159689992","https://openalex.org/W2161057551","https://openalex.org/W2167105734","https://openalex.org/W2276756108","https://openalex.org/W2290554811","https://openalex.org/W2299689687","https://openalex.org/W2312067458","https://openalex.org/W2359488065","https://openalex.org/W2412511681","https://openalex.org/W2475767983","https://openalex.org/W2505918952","https://openalex.org/W2511487031","https://openalex.org/W2756307401","https://openalex.org/W2797519282","https://openalex.org/W2810654871","https://openalex.org/W2912509330","https://openalex.org/W2922256845","https://openalex.org/W2965191972","https://openalex.org/W3021990663","https://openalex.org/W3174363935","https://openalex.org/W4250014702","https://openalex.org/W4291982393","https://openalex.org/W4295135156"],"related_works":["https://openalex.org/W262233206","https://openalex.org/W2023509574","https://openalex.org/W4324387129","https://openalex.org/W2553453169","https://openalex.org/W2299689687","https://openalex.org/W7212030808","https://openalex.org/W2521748846","https://openalex.org/W4365149260","https://openalex.org/W149137856","https://openalex.org/W2607420694"],"abstract_inverted_index":{"Promising":[0],"results":[1],"from":[2],"previous":[3],"studies":[4],"using":[5,142,255],"cell":[6,175],"therapy":[7,254],"have":[8],"paved":[9],"the":[10,56,88,161,166,178,187,198,205,271],"way":[11],"for":[12,17,268],"an":[13],"innovative":[14],"treatment":[15,65,261,295],"option":[16,267],"amyotrophic":[18],"lateral":[19],"sclerosis":[20],"(ALS).":[21],"There":[22],"is":[23],"considerable":[24],"evidence":[25],"of":[26,46,50,59,77,79,132,148,153,165,273,291],"immune":[27],"and":[28,41,73,81,116,119,135,140,155,240,265,278,286],"inflammatory":[29],"abnormalities":[30],"in":[31,69,87,110,121,186,197,216],"ALS.":[32],"Bone":[33],"marrow":[34],"mononuclear":[35],"cells":[36],"(BMMNCs)":[37],"possess":[38],"immunomodulatory":[39],"properties":[40],"could":[42],"contribute":[43],"to":[44,54,74,174,190],"slowing":[45],"disease":[47],"progression.":[48],"Aim":[49],"our":[51],"study":[52,94],"was":[53,138,158,210],"evaluate":[55,75],"long-term":[57],"effect":[58,76,277],"autologous":[60,114,256],"BMMNCs":[61,115,257],"combined":[62],"with":[63,104,150,218,259,270],"standard":[64,117,126,260],"on":[66,84],"survival":[67,85,130,184,209],"duration":[68,86,131,147,185],"a":[70,263],"large":[71],"population":[72],"type":[78],"onset":[80,154,220,225,282],"hormonal":[82,156],"status":[83,157],"intervention":[89,111,136,162,188,206],"group.":[90,163],"This":[91],"controlled,":[92],"retrospective":[93],"spanned":[95],"over":[96],"10":[97],"years,":[98],"5":[99],"months;":[100],"included":[101],"216":[102],"patients":[103,149,167,217],"probable":[105],"or":[106,177],"definite":[107],"ALS,":[108],"150":[109],"group":[112,123,134,137,189,200],"receiving":[113,124],"treatment,":[118],"66":[120],"control":[122,133,199],"only":[125],"treatment.":[127],"The":[128],"estimated":[129,183,208],"computed":[139],"compared":[141,159],"Kaplan":[143,180],"Meier":[144,181],"analysis.":[145],"Survival":[146],"different":[151],"types":[152],"within":[160],"None":[164],"reported":[168],"any":[169],"major":[170],"adverse":[171],"events":[172],"related":[173],"administration":[176],"procedure.":[179],"analysis":[182],"be":[191],"91.7":[192],"months":[193,196],"while":[194],"49.7":[195],"(p":[201,213,237,250],"=":[202,214,238,251],"0.008).":[203],"Within":[204],"group,":[207],"significantly":[211],"higher":[212],"0.013)":[215],"limb":[219],"(102.3":[221],"months)":[222,231,236,244,249],"vs.":[223,232,245],"bulbar":[224],"(49.9":[226],"months);":[227],"premenopausal":[228,284],"women":[229,234,285],"(93.1":[230],"postmenopausal":[233],"(57.6":[235],"0.002);":[239],"preandropausal":[241],"men":[242,287],"(153.7":[243],"postandropausal":[246],"males":[247],"(56.5":[248],"0.006).":[252],"Cell":[253],"along":[258],"offers":[262],"promising":[264],"safe":[266],"ALS":[269],"potential":[272],"long":[274],"term":[275],"beneficial":[276],"increased":[279],"survival.":[280],"Limb":[281],"patients,":[283],"\u2264":[288],"40":[289],"years":[290],"age":[292],"demonstrated":[293],"better":[294],"efficacy.":[296]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-10-25T00:00:00"}
