{"id":"https://openalex.org/W3206497217","doi":"https://doi.org/10.1146/annurev-med-042320-023055","title":"Organoid Models for Infectious Disease","display_name":"Organoid Models for Infectious Disease","publication_year":2021,"publication_date":"2021-10-13","ids":{"openalex":"https://openalex.org/W3206497217","doi":"https://doi.org/10.1146/annurev-med-042320-023055","mag":"3206497217","pmid":"https://pubmed.ncbi.nlm.nih.gov/34644153","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8887824"},"language":"en","primary_location":{"id":"doi:10.1146/annurev-med-042320-023055","doi":"https://doi.org/10.1146/annurev-med-042320-023055","is_oa":true,"landing_page_url":"https://doi.org/10.1146/annurev-med-042320-023055","pdf_url":"https://www.annualreviews.org/doi/pdf/10.1146/annurev-med-042320-023055","source":{"id":"https://openalex.org/S16909082","display_name":"Annual Review of Medicine","issn_l":"0066-4219","issn":["0066-4219","1545-326X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320373","host_organization_name":"Annual Reviews","host_organization_lineage":["https://openalex.org/P4310320373"],"host_organization_lineage_names":["Annual Reviews"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual Review of Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.annualreviews.org/doi/pdf/10.1146/annurev-med-042320-023055","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082644293","display_name":"Sarah Elizabeth Blutt","orcid":"https://orcid.org/0000-0002-4062-709X","observed_orcids":["https://orcid.org/0000-0002-4062-709X"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah E. Blutt","raw_affiliation_strings":["Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA;","Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA;","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087604589","display_name":"Mary Kolb Estes","orcid":"https://orcid.org/0000-0002-4813-4249","observed_orcids":["https://orcid.org/0000-0002-4813-4249"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary K. Estes","raw_affiliation_strings":["Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA","Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA;","institution_ids":["https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I181547552"],"apc_list":null,"apc_paid":null,"fwci":0.9593,"has_fulltext":true,"cited_by_count":78,"citation_normalized_percentile":{"value":0.70562423,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"73","issue":"1","first_page":"167","last_page":"182"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/organoids","display_name":"organoids","score":0.9779999852180481},{"id":"https://openalex.org/keywords/infectious-diseases","display_name":"infectious diseases","score":0.8029999732971191},{"id":"https://openalex.org/keywords/ex-vivo-infection-model","display_name":"ex vivo infection model","score":0.6899999976158142},{"id":"https://openalex.org/keywords/pluripotent-stem-cells","display_name":"pluripotent stem cells","score":0.8539999723434448},{"id":"https://openalex.org/keywords/tissue-stem-cells","display_name":"tissue stem cells","score":0.921999990940094},{"id":"https://openalex.org/keywords/host-microbe-interactions","display_name":"host-microbe interactions","score":0.9139999747276306},{"id":"https://openalex.org/keywords/respiratory-tract-infections","display_name":"respiratory infections","score":0.8610000014305115},{"id":"https://openalex.org/keywords/gastrointestinal-infections","display_name":"gastrointestinal infections","score":0.9959999918937683},{"id":"https://openalex.org/keywords/central-nervous-system-infection","display_name":"central nervous system infection","score":0.6970000267028809},{"id":"https://openalex.org/keywords/stroma","display_name":"stroma","score":0.6899999976158142},{"id":"https://openalex.org/keywords/inter-organ-communication","display_name":"inter-organ communication","score":0.9309999942779541},{"id":"https://openalex.org/keywords/microbiome","display_name":"microbiome","score":0.8830000162124634},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.6669999957084656},{"id":"https://openalex.org/keywords/host-response","display_name":"host response","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C31695470","wikidata":"https://www.wikidata.org/wiki/Q11293125","display_name":"Organoid","level":2,"score":0.9514726400375366},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.7374346852302551},{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.6741085052490234},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6135262250900269},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.5932303071022034},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5647568106651306},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.5606619119644165},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4526413083076477},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.41308334469795227},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3901479244232178},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.364909291267395},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.31898194551467896},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3136049211025238},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2733377516269684},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2238386869430542},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16159862279891968},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.14362549781799316},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13463741540908813},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.07056403160095215}],"mesh":[{"descriptor_ui":"D003141","descriptor_name":"Communicable Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1146/annurev-med-042320-023055","doi":"https://doi.org/10.1146/annurev-med-042320-023055","is_oa":true,"landing_page_url":"https://doi.org/10.1146/annurev-med-042320-023055","pdf_url":"https://www.annualreviews.org/doi/pdf/10.1146/annurev-med-042320-023055","source":{"id":"https://openalex.org/S16909082","display_name":"Annual Review of Medicine","issn_l":"0066-4219","issn":["0066-4219","1545-326X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320373","host_organization_name":"Annual Reviews","host_organization_lineage":["https://openalex.org/P4310320373"],"host_organization_lineage_names":["Annual Reviews"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual Review of Medicine","raw_type":"journal-article"},{"id":"pmid:34644153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34644153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual review of medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8887824","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8887824","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Annu Rev Med","raw_type":"Text"},{"id":"pmh:oai:digitalcommons.library.tmc.edu:baylor_docs-2825","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.library.tmc.edu/baylor_docs/1851","pdf_url":null,"source":{"id":"https://openalex.org/S4377196655","display_name":"Digital Commons-TMC (Texas Medical Center)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1337852284","host_organization_name":"Texas Medical Center","host_organization_lineage":["https://openalex.org/I1337852284"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty and Staff Publications","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1146/annurev-med-042320-023055","doi":"https://doi.org/10.1146/annurev-med-042320-023055","is_oa":true,"landing_page_url":"https://doi.org/10.1146/annurev-med-042320-023055","pdf_url":"https://www.annualreviews.org/doi/pdf/10.1146/annurev-med-042320-023055","source":{"id":"https://openalex.org/S16909082","display_name":"Annual Review of Medicine","issn_l":"0066-4219","issn":["0066-4219","1545-326X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320373","host_organization_name":"Annual Reviews","host_organization_lineage":["https://openalex.org/P4310320373"],"host_organization_lineage_names":["Annual Reviews"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual Review of Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1026775581","display_name":"Limited Competition for the Continuation of the Intestinal Stem Cell Consortium Coordinating Center","funder_award_id":"U24DK085532","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G221969947","display_name":"Mechanisms of Norovirus Pathogenesis and Replication to Develop Therapeutics","funder_award_id":"P01AI057788","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5528847237","display_name":"Integrated Genomics of Mucosal Infections","funder_award_id":"U19AI144297","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6751829226","display_name":"Intestinal Niche in Homeostasis and Epithelial Regeneration","funder_award_id":"U01DK103168","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8395882484","display_name":"Intestinal Stem Cell Consortium Coordinating Center","funder_award_id":"U01DK085532","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000893404","display_name":"Texas Medical Center Digestive Diseases Center","funder_award_id":"P30DK056338","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000910299","display_name":"Human Biomimetics for Mucosal Infections","funder_award_id":"U19AI116497","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3206497217.pdf","grobid_xml":"https://content.openalex.org/works/W3206497217.grobid-xml"},"referenced_works_count":103,"referenced_works":["https://openalex.org/W119811458","https://openalex.org/W1483496013","https://openalex.org/W1591361110","https://openalex.org/W1750074072","https://openalex.org/W1769758742","https://openalex.org/W1802574002","https://openalex.org/W1848527143","https://openalex.org/W1910612799","https://openalex.org/W1965157206","https://openalex.org/W1973717042","https://openalex.org/W1979535562","https://openalex.org/W1996955003","https://openalex.org/W2000151960","https://openalex.org/W2002513358","https://openalex.org/W2013520568","https://openalex.org/W2018286352","https://openalex.org/W2021544537","https://openalex.org/W2031522785","https://openalex.org/W2047743944","https://openalex.org/W2050707891","https://openalex.org/W2054186703","https://openalex.org/W2055860761","https://openalex.org/W2076312582","https://openalex.org/W2085652695","https://openalex.org/W2085844606","https://openalex.org/W2086943348","https://openalex.org/W2117098504","https://openalex.org/W2127479534","https://openalex.org/W2130744572","https://openalex.org/W2136678404","https://openalex.org/W2138977668","https://openalex.org/W2143296478","https://openalex.org/W2147832388","https://openalex.org/W2152161931","https://openalex.org/W2156862506","https://openalex.org/W2164422245","https://openalex.org/W2168752825","https://openalex.org/W2193652497","https://openalex.org/W2195294260","https://openalex.org/W2209535620","https://openalex.org/W2287258646","https://openalex.org/W2300378039","https://openalex.org/W2311770845","https://openalex.org/W2341041396","https://openalex.org/W2346188149","https://openalex.org/W2356757232","https://openalex.org/W2508798274","https://openalex.org/W2582900298","https://openalex.org/W2597789565","https://openalex.org/W2603154743","https://openalex.org/W2609844460","https://openalex.org/W2761945803","https://openalex.org/W2766834702","https://openalex.org/W2769543984","https://openalex.org/W2788650088","https://openalex.org/W2790122594","https://openalex.org/W2791909710","https://openalex.org/W2793065417","https://openalex.org/W2799736418","https://openalex.org/W2800487560","https://openalex.org/W2802943395","https://openalex.org/W2807853324","https://openalex.org/W2809107133","https://openalex.org/W2848847391","https://openalex.org/W2903001230","https://openalex.org/W2906738980","https://openalex.org/W2908361053","https://openalex.org/W2917423992","https://openalex.org/W2919899673","https://openalex.org/W2920830037","https://openalex.org/W2922000510","https://openalex.org/W2939543377","https://openalex.org/W2943439515","https://openalex.org/W2944263569","https://openalex.org/W2944420557","https://openalex.org/W2972775856","https://openalex.org/W2977861929","https://openalex.org/W2980995354","https://openalex.org/W2982358030","https://openalex.org/W2982359969","https://openalex.org/W2986542070","https://openalex.org/W2990026706","https://openalex.org/W2995456137","https://openalex.org/W2996819431","https://openalex.org/W3002451359","https://openalex.org/W3009070575","https://openalex.org/W3010955108","https://openalex.org/W3013151148","https://openalex.org/W3013494244","https://openalex.org/W3013580096","https://openalex.org/W3020909574","https://openalex.org/W3024445339","https://openalex.org/W3025559601","https://openalex.org/W3032142305","https://openalex.org/W3096177766","https://openalex.org/W3100695431","https://openalex.org/W3110287817","https://openalex.org/W3118627743","https://openalex.org/W3120633623","https://openalex.org/W3120919885","https://openalex.org/W3155510140","https://openalex.org/W3178295071","https://openalex.org/W4249288755"],"related_works":["https://openalex.org/W4297493964","https://openalex.org/W2769694736","https://openalex.org/W2520461980","https://openalex.org/W4311499466","https://openalex.org/W3206693498","https://openalex.org/W7160844055","https://openalex.org/W2591673937","https://openalex.org/W2797324120","https://openalex.org/W4412354031","https://openalex.org/W4413294092"],"abstract_inverted_index":{"Infectious":[0],"diseases":[1],"affect":[2],"individual":[3],"health":[4,100],"and":[5,21,27,31,54,63,76],"have":[6],"widespread":[7],"societal":[8],"impacts.":[9],"New":[10],"ex":[11],"vivo":[12,52],"models":[13,46,86],"are":[14,55],"critical":[15],"to":[16,24,97,102],"understand":[17],"pathogenesis,":[18],"host":[19],"response,":[20],"features":[22],"necessary":[23],"develop":[25],"preventive":[26],"therapeutic":[28],"treatments.":[29],"Pluripotent":[30],"tissue":[32],"stem":[33],"cell-derived":[34],"organoids":[35,84],"provide":[36,91],"new":[37,57],"tools":[38],"for":[39,87],"the":[40,72,77,81,95],"study":[41],"of":[42,50,83],"human":[43,60,99],"infections.":[44],"Organoid":[45,89],"recapitulate":[47],"many":[48],"characteristics":[49],"in":[51],"disease":[53],"providing":[56],"insights":[58],"into":[59],"respiratory,":[61],"gastrointestinal,":[62],"neuronal":[64],"host-microbe":[65],"interactions.":[66],"Increasing":[67],"culture":[68],"complexity":[69],"by":[70],"adding":[71],"stroma,":[73],"interorgan":[74],"communication,":[75],"microbiome":[78],"will":[79],"improve":[80,98],"use":[82],"as":[85],"infection.":[88],"cultures":[90],"a":[92],"platform":[93],"with":[94],"capability":[96],"related":[101],"infectious":[103],"diseases.":[104]},"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":22},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-10-25T00:00:00"}
