{"id":"https://openalex.org/W3206027018","doi":"https://doi.org/10.1016/s1569-1993(21)02084-1","title":"661: W1282X cystic fibrosis mouse models for examining in vivo nonsense mutation correction","display_name":"661: W1282X cystic fibrosis mouse models for examining in vivo nonsense mutation correction","publication_year":2021,"publication_date":"2021-10-19","ids":{"openalex":"https://openalex.org/W3206027018","doi":"https://doi.org/10.1016/s1569-1993(21)02084-1","mag":"3206027018"},"language":"en","primary_location":{"id":"doi:10.1016/s1569-1993(21)02084-1","doi":"https://doi.org/10.1016/s1569-1993(21)02084-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1569-1993(21)02084-1","pdf_url":"https://doi.org/10.1016/s1569-1993(21)02084-1","source":{"id":"https://openalex.org/S147774598","display_name":"Journal of Cystic Fibrosis","issn_l":"1569-1993","issn":["1569-1993","1873-5010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cystic Fibrosis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s1569-1993(21)02084-1","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026568844","display_name":"M. Michicich","orcid":"https://orcid.org/0000-0003-2841-2966","observed_orcids":["https://orcid.org/0000-0003-2841-2966"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Michicich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Z. Traylor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z. Traylor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022020811","display_name":"David F. LePage","orcid":"https://orcid.org/0009-0008-3820-0645","observed_orcids":["https://orcid.org/0009-0008-3820-0645"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. LePage","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065884334","display_name":"Rachel J. Mann","orcid":"https://orcid.org/0009-0007-4558-2947","observed_orcids":["https://orcid.org/0009-0007-4558-2947"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Mann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039228510","display_name":"Wenxuan Jiang","orcid":"https://orcid.org/0000-0003-4852-6055","observed_orcids":["https://orcid.org/0000-0003-4852-6055"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. Jiang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045894147","display_name":"Thomas J. Kelley","orcid":"https://orcid.org/0000-0001-9236-7907","observed_orcids":["https://orcid.org/0000-0001-9236-7907","https://orcid.org/0000-0003-3867-4433"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Kelley","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005227452","display_name":"Ronald A. Conlon","orcid":"https://orcid.org/0009-0000-8601-8129","observed_orcids":["https://orcid.org/0009-0000-8601-8129"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Conlon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102902607","display_name":"Mitchell L. Drumm","orcid":"https://orcid.org/0000-0003-4739-5153","observed_orcids":["https://orcid.org/0000-0003-4739-5153","https://orcid.org/0000-0002-8147-3621"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Drumm","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000895244","display_name":"Craig A. Hodges","orcid":"https://orcid.org/0000-0003-3332-9024","observed_orcids":["https://orcid.org/0000-0003-3332-9024"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Hodges","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3700,"currency":"USD","value_usd":3700},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":null,"first_page":"S313","last_page":"S314"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonsense-mutation","display_name":"nonsense mutation","score":0.6420000195503235},{"id":"https://openalex.org/keywords/cftr","display_name":"CFTR","score":0.828000009059906}],"concepts":[{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.9607834815979004},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9132513999938965},{"id":"https://openalex.org/C62923972","wikidata":"https://www.wikidata.org/wiki/Q600499","display_name":"Nonsense","level":3,"score":0.7426700592041016},{"id":"https://openalex.org/C96777560","wikidata":"https://www.wikidata.org/wiki/Q518638","display_name":"Nonsense mutation","level":5,"score":0.6628405451774597},{"id":"https://openalex.org/C2776502428","wikidata":"https://www.wikidata.org/wiki/Q6095693","display_name":"Ivacaftor","level":4,"score":0.6384234428405762},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.45803406834602356},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.45119708776474},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3274267315864563},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20020851492881775},{"id":"https://openalex.org/C2778428886","wikidata":"https://www.wikidata.org/wiki/Q420470","display_name":"Cystic fibrosis transmembrane conductance regulator","level":3,"score":0.1798408031463623},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16467982530593872},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11475571990013123},{"id":"https://openalex.org/C75563809","wikidata":"https://www.wikidata.org/wiki/Q2656896","display_name":"Missense mutation","level":4,"score":0.08785867691040039},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.04570037126541138}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s1569-1993(21)02084-1","doi":"https://doi.org/10.1016/s1569-1993(21)02084-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1569-1993(21)02084-1","pdf_url":"https://doi.org/10.1016/s1569-1993(21)02084-1","source":{"id":"https://openalex.org/S147774598","display_name":"Journal of Cystic Fibrosis","issn_l":"1569-1993","issn":["1569-1993","1873-5010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cystic Fibrosis","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s1569-1993(21)02084-1","doi":"https://doi.org/10.1016/s1569-1993(21)02084-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1569-1993(21)02084-1","pdf_url":"https://doi.org/10.1016/s1569-1993(21)02084-1","source":{"id":"https://openalex.org/S147774598","display_name":"Journal of Cystic Fibrosis","issn_l":"1569-1993","issn":["1569-1993","1873-5010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cystic Fibrosis","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3206027018.pdf","grobid_xml":"https://content.openalex.org/works/W3206027018.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W2999796954"],"related_works":["https://openalex.org/W3205696916","https://openalex.org/W3205530631","https://openalex.org/W4300863562","https://openalex.org/W4300863139","https://openalex.org/W4401324549","https://openalex.org/W3038887944","https://openalex.org/W4402234519","https://openalex.org/W7220853607","https://openalex.org/W4386050494","https://openalex.org/W4319440992"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-10-25T00:00:00"}