{"id":"https://openalex.org/W3205745580","doi":null,"title":"The application of Gensini score and IL-1ra in assessing the condition and prognosis of patients with coronary artery disease.","display_name":"The application of Gensini score and IL-1ra in assessing the condition and prognosis of patients with coronary artery disease.","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3205745580","mag":"3205745580","pmid":"https://pubmed.ncbi.nlm.nih.gov/34650711","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8506997"},"language":"en","primary_location":{"id":"pmid:34650711","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34650711","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8506997/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101810205","display_name":"Qian He","orcid":"https://orcid.org/0000-0003-3744-8805","observed_orcids":["https://orcid.org/0000-0003-3744-8805"]},"institutions":[{"id":"https://openalex.org/I4210117378","display_name":"Taihe Hospital","ror":"https://ror.org/02ftdsn70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210117378"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian He","raw_affiliation_strings":["Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China","institution_ids":["https://openalex.org/I4210117378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101902234","display_name":"Pu Zhang","orcid":"https://orcid.org/0000-0003-1454-516X","observed_orcids":["https://orcid.org/0000-0003-1454-516X"]},"institutions":[{"id":"https://openalex.org/I4210117378","display_name":"Taihe Hospital","ror":"https://ror.org/02ftdsn70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210117378"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pu Zhang","raw_affiliation_strings":["Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China","institution_ids":["https://openalex.org/I4210117378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100617012","display_name":"Yu Li","orcid":"https://orcid.org/0000-0002-8580-0319","observed_orcids":["https://orcid.org/0000-0002-8580-0319"]},"institutions":[{"id":"https://openalex.org/I4210117378","display_name":"Taihe Hospital","ror":"https://ror.org/02ftdsn70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210117378"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Li","raw_affiliation_strings":["Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China","institution_ids":["https://openalex.org/I4210117378"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chao Cai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117378","display_name":"Taihe Hospital","ror":"https://ror.org/02ftdsn70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210117378"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Cai","raw_affiliation_strings":["Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China","institution_ids":["https://openalex.org/I4210117378"]}]},{"author_position":"last","author":{"id":null,"display_name":"Chongquan Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117378","display_name":"Taihe Hospital","ror":"https://ror.org/02ftdsn70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210117378"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chongquan Wang","raw_affiliation_strings":["Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei Province, China","institution_ids":["https://openalex.org/I4210117378"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210117378"],"apc_list":null,"apc_paid":null,"fwci":2.2768,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.89743362,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"13","issue":"9","first_page":"10421","last_page":"10427"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.30469998717308044,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.30469998717308044,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.21220000088214874,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.164900004863739,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gensini-score","display_name":"Gensini score","score":0.9929999709129333},{"id":"https://openalex.org/keywords/interleukin-1-receptor-antagonist","display_name":"interleukin-1 receptor antagonist","score":0.9959999918937683},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.8769999742507935},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.6539999842643738},{"id":"https://openalex.org/keywords/grace-score","display_name":"GRACE risk score","score":0.7329999804496765},{"id":"https://openalex.org/keywords/troponin","display_name":"troponin","score":0.9919999837875366},{"id":"https://openalex.org/keywords/stable-angina","display_name":"stable angina","score":0.8289999961853027},{"id":"https://openalex.org/keywords/unstable-angina","display_name":"unstable angina","score":1.0},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.9990000128746033},{"id":"https://openalex.org/keywords/major-adverse-cardiovascular-events","display_name":"major adverse cardiovascular events","score":0.9110000133514404},{"id":"https://openalex.org/keywords/disease-severity-assessment","display_name":"disease severity assessment","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7836626768112183},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.753595232963562},{"id":"https://openalex.org/C2777785093","wikidata":"https://www.wikidata.org/wiki/Q2032041","display_name":"Unstable angina","level":3,"score":0.6891608238220215},{"id":"https://openalex.org/C2780739214","wikidata":"https://www.wikidata.org/wiki/Q6723023","display_name":"Mace","level":4,"score":0.6629087924957275},{"id":"https://openalex.org/C2777014857","wikidata":"https://www.wikidata.org/wiki/Q1383410","display_name":"Exacerbation","level":2,"score":0.5528339147567749},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.5284827947616577},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5215339660644531},{"id":"https://openalex.org/C115725540","wikidata":"https://www.wikidata.org/wiki/Q7846263","display_name":"Troponin I","level":3,"score":0.49017056822776794},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:34650711","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34650711","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8506997","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8506997/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},{"id":"mag:3205745580","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34650711/","pdf_url":null,"source":{"id":"https://openalex.org/S25983388","display_name":"American Journal of Translational Research","issn_l":"1943-8141","issn":["1943-8141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320994","host_organization_name":"e-Century Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310320994"],"host_organization_lineage_names":["e-Century Publishing Corporation"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Translational Research","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8506997","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8506997/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1505055902","https://openalex.org/W2126330644","https://openalex.org/W2507859826","https://openalex.org/W2568281451","https://openalex.org/W2569385277","https://openalex.org/W2580467049","https://openalex.org/W2581409474","https://openalex.org/W2603125086","https://openalex.org/W2608267856","https://openalex.org/W2610249974","https://openalex.org/W2611808489","https://openalex.org/W2612654136","https://openalex.org/W2727764505","https://openalex.org/W2747404832","https://openalex.org/W2766152280","https://openalex.org/W2766491028","https://openalex.org/W2767520081","https://openalex.org/W2768944666","https://openalex.org/W2775363656","https://openalex.org/W2793851406","https://openalex.org/W2804326393","https://openalex.org/W2806552872","https://openalex.org/W2810714464","https://openalex.org/W2980322643","https://openalex.org/W2992445468"],"related_works":["https://openalex.org/W2113396136","https://openalex.org/W3209094211","https://openalex.org/W2786319405","https://openalex.org/W4206980211","https://openalex.org/W7207625399","https://openalex.org/W4288687552","https://openalex.org/W2359808701","https://openalex.org/W4390127378","https://openalex.org/W2885259384","https://openalex.org/W2088192954"],"abstract_inverted_index":{"OBJECTIVE:":[0],"This":[1],"study":[2],"aimed":[3],"to":[4,31,110,118],"investigate":[5],"the":[6,18,71,123,137,147,159],"value":[7],"of":[8,22,139,149,162],"Gensini":[9,60,77,119,131],"score":[10,78,132],"and":[11,20,51,65,79,83,103,122,133,145,151],"interleukin-1":[12],"receptor":[13],"antagonist":[14],"(IL-1ra)":[15],"in":[16,70,141,158],"assessing":[17],"condition":[19],"prognosis":[21,105],"patients":[23,35,88,142,163],"with":[24,116,143,164],"coronary":[25],"heart":[26],"disease":[27],"(CHD).":[28],"METHODS:":[29],"According":[30],"their":[32],"condition,":[33],"175":[34],"were":[36,68,85,89],"divided":[37,90],"into":[38,91],"stable":[39],"angina":[40,46],"group":[41,47,55,93,99,106],"(SA,":[42],"60":[43,49],"cases),":[44,95],"unstable":[45],"(UA,":[48],"cases)":[50,102,108],"acute":[52],"myocardial":[53],"infarction":[54],"(AMI,":[56],"55":[57],"cases).":[58],"The":[59,74,87,113],"score,":[61,63,81,120],"GRACE":[62,80],"IL-1ra":[64,82,121,134],"troponin":[66],"(Tn)":[67],"compared":[69],"three":[72],"groups.":[73],"correlation":[75],"between":[76],"Tn,":[84],"explored.":[86],"death":[92],"(21":[94],"adverse":[96],"cardiovascular":[97],"events":[98],"(MACE,":[100],"50":[101],"good":[104],"(104":[107],"according":[109],"clinical":[111,124],"outcomes.":[112],"ROC":[114],"curve":[115],"regard":[117],"outcome":[125],"was":[126],"plotted.":[127],"RESULTS:":[128],"<0.001).":[129],"CONCLUSION:":[130],"reflect":[135],"better":[136],"severity":[138],"CHD":[140],"CHD,":[144],"also":[146],"AUC":[148],"0.9350":[150],"0.9499":[152],"(P<0.001).":[153],"It":[154],"can":[155],"be":[156],"used":[157],"prognostic":[160],"evaluation":[161],"CHD.":[165]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-10-25T00:00:00"}