{"id":"https://openalex.org/W3205573441","doi":"https://doi.org/10.1136/archdischild-2021-322890","title":"Surfactant therapy in late preterm and term neonates with respiratory distress syndrome: a systematic review and meta-analysis","display_name":"Surfactant therapy in late preterm and term neonates with respiratory distress syndrome: a systematic review and meta-analysis","publication_year":2021,"publication_date":"2021-10-22","ids":{"openalex":"https://openalex.org/W3205573441","doi":"https://doi.org/10.1136/archdischild-2021-322890","mag":"3205573441","pmid":"https://pubmed.ncbi.nlm.nih.gov/34686533"},"language":"en","primary_location":{"id":"doi:10.1136/archdischild-2021-322890","doi":"https://doi.org/10.1136/archdischild-2021-322890","is_oa":false,"landing_page_url":"https://doi.org/10.1136/archdischild-2021-322890","pdf_url":null,"source":{"id":"https://openalex.org/S35570472","display_name":"Archives of Disease in Childhood Fetal & Neonatal","issn_l":"1359-2998","issn":["1359-2998","1468-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/journal_contribution/Surfactant_therapy_in_late_preterm_and_term_neonates_with_respiratory_distress_syndrome_a_systematic_review_and_meta-analysis/17048540","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029288530","display_name":"Viraraghavan Vadakkencherry Ramaswamy","orcid":"https://orcid.org/0000-0001-7092-3597","observed_orcids":["https://orcid.org/0000-0001-7092-3597"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Viraraghavan Vadakkencherry Ramaswamy","raw_affiliation_strings":["Department of Neonatology, Ankura Hospital for Women and Children, Hyderabad, Telangana, India"],"raw_orcid":"https://orcid.org/0000-0001-7092-3597","affiliations":[{"raw_affiliation_string":"Department of Neonatology, Ankura Hospital for Women and Children, Hyderabad, Telangana, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057197601","display_name":"Thangaraj Abiramalatha","orcid":"https://orcid.org/0000-0001-9125-3510","observed_orcids":["https://orcid.org/0000-0001-9125-3510"]},"institutions":[{"id":"https://openalex.org/I20107917","display_name":"Sri Ramachandra Institute of Higher Education and Research","ror":"https://ror.org/0108gdg43","country_code":"IN","type":"education","lineage":["https://openalex.org/I20107917"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Thangaraj Abiramalatha","raw_affiliation_strings":["Department of Neonatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, India","institution_ids":["https://openalex.org/I20107917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023465294","display_name":"Tapas Bandyopadhyay","orcid":"https://orcid.org/0000-0001-6872-0942","observed_orcids":["https://orcid.org/0000-0001-6872-0942"]},"institutions":[{"id":"https://openalex.org/I2800585909","display_name":"Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital","ror":"https://ror.org/00qa63322","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800585909"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tapas Bandyopadhyay","raw_affiliation_strings":["Department of Neonatology, Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, Delhi, India","institution_ids":["https://openalex.org/I2800585909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047180564","display_name":"Elaine Margaret Boyle","orcid":"https://orcid.org/0000-0002-5038-3148","observed_orcids":["https://orcid.org/0000-0002-5038-3148"]},"institutions":[{"id":"https://openalex.org/I153648349","display_name":"University of Leicester","ror":"https://ror.org/04h699437","country_code":"GB","type":"education","lineage":["https://openalex.org/I153648349"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Elaine Boyle","raw_affiliation_strings":["Department of Health Sciences, University of Leicester, Leicester, UK"],"raw_orcid":"https://orcid.org/0000-0002-5038-3148","affiliations":[{"raw_affiliation_string":"Department of Health Sciences, University of Leicester, Leicester, UK","institution_ids":["https://openalex.org/I153648349"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073238754","display_name":"Charles Christoph Roehr","orcid":"https://orcid.org/0000-0001-7965-4637","observed_orcids":["https://orcid.org/0000-0001-7965-4637"]},"institutions":[{"id":"https://openalex.org/I1307034911","display_name":"North Bristol NHS Trust","ror":"https://ror.org/036x6gt55","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307034911","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I2801253297","display_name":"Southmead Hospital","ror":"https://ror.org/05d576879","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801253297","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Charles Christoph Roehr","raw_affiliation_strings":["Faculty of Health Sciences, University of Bristol, Bristol, UK","Newborn Services, Southmead Hospital, North Bristol Trust, Bristol, UK","Nuffield Department of Population Health, Medical Sciences Division, National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK","Nuffield Department of Population Health, Medical Sciences, Division, University of Oxford, National Perinatal Epidemiology Unit, Oxford OX3 7LF, Oxfordshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"Newborn Services, Southmead Hospital, North Bristol Trust, Bristol, UK","institution_ids":["https://openalex.org/I1307034911","https://openalex.org/I2801253297"]},{"raw_affiliation_string":"Nuffield Department of Population Health, Medical Sciences Division, National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Nuffield Department of Population Health, Medical Sciences, Division, University of Oxford, National Perinatal Epidemiology Unit, Oxford OX3 7LF, Oxfordshire, UK","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5073238754"],"corresponding_institution_ids":["https://openalex.org/I1307034911","https://openalex.org/I2801253297","https://openalex.org/I36234482","https://openalex.org/I40120149"],"apc_list":null,"apc_paid":null,"fwci":0.8958,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.69711661,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"107","issue":"4","first_page":"393","last_page":"397"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11586","display_name":"Congenital Diaphragmatic Hernia Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/surfactant-replacement-therapy","display_name":"surfactant therapy","score":0.9610000252723694},{"id":"https://openalex.org/keywords/respiratory-distress-syndrome","display_name":"respiratory distress syndrome","score":0.925000011920929},{"id":"https://openalex.org/keywords/late-preterm-infants","display_name":"late preterm infants","score":0.9210000038146973},{"id":"https://openalex.org/keywords/term-infants","display_name":"term infants","score":0.9319999814033508},{"id":"https://openalex.org/keywords/neonatal-mortality","display_name":"neonatal mortality","score":0.9679999947547913},{"id":"https://openalex.org/keywords/invasive-mechanical-ventilation","display_name":"invasive mechanical ventilation","score":0.9760000109672546},{"id":"https://openalex.org/keywords/air-leak","display_name":"air leakage","score":0.7379999756813049},{"id":"https://openalex.org/keywords/persistent-pulmonary-hypertension-of-the-newborn","display_name":"persistent pulmonary hypertension of the newborn","score":0.9990000128746033},{"id":"https://openalex.org/keywords/non-invasive-respiratory-support","display_name":"non-invasive respiratory support","score":0.9340000152587891},{"id":"https://openalex.org/keywords/continuous-positive-airway-pressure","display_name":"continuous positive airway pressure","score":0.9269999861717224},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7971225380897522},{"id":"https://openalex.org/C2776953283","wikidata":"https://www.wikidata.org/wiki/Q17125052","display_name":"Surfactant therapy","level":4,"score":0.7706714868545532},{"id":"https://openalex.org/C141983124","wikidata":"https://www.wikidata.org/wiki/Q188008","display_name":"Respiratory distress","level":2,"score":0.7423082590103149},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.7005348205566406},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.6643072366714478},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.6356909871101379},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6219430565834045},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.5274819731712341},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.4869004786014557},{"id":"https://openalex.org/C2780395437","wikidata":"https://www.wikidata.org/wiki/Q754348","display_name":"Neonatal respiratory distress syndrome","level":4,"score":0.4799659252166748},{"id":"https://openalex.org/C2776691311","wikidata":"https://www.wikidata.org/wiki/Q1621803","display_name":"High-frequency ventilation","level":3,"score":0.42530357837677},{"id":"https://openalex.org/C2776596748","wikidata":"https://www.wikidata.org/wiki/Q6803612","display_name":"Mean airway pressure","level":3,"score":0.4216095209121704},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3895334005355835},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.37775182723999023},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.296220064163208},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2702159285545349},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.11678779125213623},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.06730610132217407},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011663","descriptor_name":"Pulmonary Surfactants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013501","descriptor_name":"Surface-Active Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045422","descriptor_name":"Continuous Positive Airway Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1136/archdischild-2021-322890","doi":"https://doi.org/10.1136/archdischild-2021-322890","is_oa":false,"landing_page_url":"https://doi.org/10.1136/archdischild-2021-322890","pdf_url":null,"source":{"id":"https://openalex.org/S35570472","display_name":"Archives of Disease in Childhood Fetal & Neonatal","issn_l":"1359-2998","issn":["1359-2998","1468-2052"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","raw_type":"journal-article"},{"id":"pmid:34686533","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34686533","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of disease in childhood. Fetal and neonatal edition","raw_type":"Journal Article"},{"id":"pmh:oai:figshare.com:article/17048540","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Surfactant_therapy_in_late_preterm_and_term_neonates_with_respiratory_distress_syndrome_a_systematic_review_and_meta-analysis/17048540","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/7c990bd4-5f72-4409-9487-3a791d4492f3","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/7c990bd4-5f72-4409-9487-3a791d4492f3","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ramaswamy, V V, Abiramalatha, T, Bandyopadhyay, T, Boyle, E & Roehr, C C 2022, 'Surfactant therapy in late preterm and term neonates with respiratory distress syndrome : a systematic review and meta-analysis', Archives of disease in childhood. Fetal and neonatal edition, vol. 107, no. 4, pp. 393-397. https://doi.org/10.1136/archdischild-2021-322890","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/17048540","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Surfactant_therapy_in_late_preterm_and_term_neonates_with_respiratory_distress_syndrome_a_systematic_review_and_meta-analysis/17048540","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[{"id":"https://openalex.org/G3807726673","display_name":"Multicentre open label, pragmatic randomised controlled trial of early surfactant therapy versus expectant management in late preterm and early term infants with respiratory distress","funder_award_id":"17/89/07","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W185167656","https://openalex.org/W202552613","https://openalex.org/W1498194326","https://openalex.org/W1516055747","https://openalex.org/W1754063520","https://openalex.org/W1986104814","https://openalex.org/W1986244006","https://openalex.org/W2023101127","https://openalex.org/W2028758728","https://openalex.org/W2045112989","https://openalex.org/W2052811370","https://openalex.org/W2061456754","https://openalex.org/W2066046656","https://openalex.org/W2082977560","https://openalex.org/W2087003039","https://openalex.org/W2136403658","https://openalex.org/W2149876847","https://openalex.org/W2156098321","https://openalex.org/W2160226288","https://openalex.org/W2164024692","https://openalex.org/W2192061494","https://openalex.org/W2356320216","https://openalex.org/W2531269403","https://openalex.org/W2585662074","https://openalex.org/W2604358497","https://openalex.org/W2727398316","https://openalex.org/W2906459187","https://openalex.org/W2936595371","https://openalex.org/W2947088302","https://openalex.org/W2970684805","https://openalex.org/W2991792334","https://openalex.org/W3009029729","https://openalex.org/W3088956462","https://openalex.org/W3126922579","https://openalex.org/W3133933097","https://openalex.org/W3155590165","https://openalex.org/W3159701087"],"related_works":["https://openalex.org/W2604358497","https://openalex.org/W2244162321","https://openalex.org/W3037650590","https://openalex.org/W2040861967","https://openalex.org/W4381663190","https://openalex.org/W4415982801","https://openalex.org/W2398176900","https://openalex.org/W2906025868","https://openalex.org/W2343650518","https://openalex.org/W4301160510"],"abstract_inverted_index":{"Background":[0],"There":[1],"are":[2,272],"no":[3],"evidence-based":[4],"recommendations":[5],"for":[6,57,261],"surfactant":[7,29,122,148,164,192,224,264],"use":[8,123,193],"in":[9,30,146,200,226,266],"late":[10],"preterm":[11],"(LPT)":[12],"and":[13,26,32,41,55,67,75,86,187,216,228,243,257],"term":[14,33,87,229],"infants":[15,34,112,155,230],"with":[16,35,89,99,114,127,196,231],"respiratory":[17,116,246],"distress":[18],"syndrome":[19],"(RDS).":[20],"Objective":[21],"To":[22],"investigate":[23],"the":[24,64,84,168,185,209,251,267],"safety":[25],"efficacy":[27],"of":[28,49,105,131,170,202,208,213,238,245,250],"LPT":[31,85,227],"RDS.":[36],"Methods":[37],"Systematic":[38],"review,":[39],"meta-analysis":[40],"evidence":[42,106,221],"grading.":[43],"Interventions":[44],"Surfactant":[45],"therapy":[46,225],"versus":[47],"standard":[48],"care.":[50],"Main":[51],"outcome":[52],"measures":[53],"Mortality":[54],"requirement":[56],"invasive":[58],"mechanical":[59],"ventilation":[60],"(IMV).":[61],"Results":[62],"Of":[63,83],"7970":[65],"titles":[66],"abstracts":[68],"screened,":[69],"17":[70],"studies":[71,74,110],"(16":[72],"observational":[73,109,144,188],"1":[76],"randomised":[77],"controlled":[78],"trial":[79],"(RCT))":[80],"were":[81,97],"included.":[82],"neonates":[88],"RDS,":[90],"46%":[91],"(95%":[92],"CI":[93,136,175],"40%":[94],"to":[95,138,154,177,181,253],"51%)":[96],"treated":[98],"surfactant.":[100],"We":[101],"found":[102],"moderate":[103],"certainty":[104],"(CoE)":[107],"from":[108,143,184],"evaluating":[111],"supported":[113],"non-invasive":[115],"support":[117],"(NRS)":[118],"or":[119],"IMV":[120,171],"that":[121,163,191],"may":[124],"be":[125],"associated":[126,195],"a":[128,197,234],"decreased":[129,236],"risk":[130,169,201,237],"mortality":[132],"(OR":[133,172],"0.45,":[134],"95%":[135,174],"0.32":[137],"0.64).":[139],"Very":[140,179],"low":[141,180,182,252,255],"CoE":[142,183,256],"trials":[145,189,271],"which":[147],"was":[149,194],"administered":[150],"at":[151],"FiO2":[152],">0.30\u20130.40":[153],"on":[156,223,263],"Continuous":[157],"Positive":[158],"Airway":[159],"Pressure":[160],"(CPAP)":[161],"indicated":[162],"did":[165],"not":[166],"decrease":[167,199],"1.20,":[173],"0.40":[176],"3.56).":[178],"RCT":[186],"showed":[190],"significant":[198],"air":[203,240],"leak,":[204,241],"persistent":[205],"pulmonary":[206],"hypertension":[207],"newborn":[210],"(PPHN),":[211],"duration":[212,244],"IMV,":[214],"NRS":[215],"hospital":[217],"stay.":[218],"Conclusions":[219],"Current":[220],"base":[222],"RDS":[232],"indicates":[233],"potentially":[235],"mortality,":[239],"PPHN":[242],"support.":[247],"In":[248],"view":[249],"very":[254],"widely":[258],"varying":[259],"thresholds":[260],"deciding":[262],"replacement":[265],"included":[268],"studies,":[269],"further":[270],"needed.":[273]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":19},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-10-25T00:00:00"}
