{"id":"https://openalex.org/W3204474465","doi":"https://doi.org/10.1016/j.cbi.2021.109678","title":"New quaternized pyridinium derivatives of betulin: Synthesis and evaluation of membranotropic properties on liposomes, pro- and eukaryotic cells, and isolated mitochondria","display_name":"New quaternized pyridinium derivatives of betulin: Synthesis and evaluation of membranotropic properties on liposomes, pro- and eukaryotic cells, and isolated mitochondria","publication_year":2021,"publication_date":"2021-10-01","ids":{"openalex":"https://openalex.org/W3204474465","doi":"https://doi.org/10.1016/j.cbi.2021.109678","mag":"3204474465","pmid":"https://pubmed.ncbi.nlm.nih.gov/34600868"},"language":"en","primary_location":{"id":"doi:10.1016/j.cbi.2021.109678","doi":"https://doi.org/10.1016/j.cbi.2021.109678","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cbi.2021.109678","pdf_url":null,"source":{"id":"https://openalex.org/S34460812","display_name":"Chemico-Biological Interactions","issn_l":"0009-2797","issn":["0009-2797","1872-7786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-Biological Interactions","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037236045","display_name":"Mikhail V. Dubinin","orcid":"https://orcid.org/0000-0002-7453-3390","observed_orcids":["https://orcid.org/0000-0002-7453-3390"]},"institutions":[{"id":"https://openalex.org/I3132405765","display_name":"Mari State University","ror":"https://ror.org/01yjw8d43","country_code":"RU","type":"education","lineage":["https://openalex.org/I3132405765"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Mikhail V. Dubinin","raw_affiliation_strings":["Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia. Electronic address: dubinin1989@gmail.com","Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia"],"raw_orcid":"https://orcid.org/0000-0002-7453-3390","affiliations":[{"raw_affiliation_string":"Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia. Electronic address: dubinin1989@gmail.com","institution_ids":["https://openalex.org/I3132405765"]},{"raw_affiliation_string":"Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia","institution_ids":["https://openalex.org/I3132405765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089252258","display_name":"Alena A. Semenova","orcid":"https://orcid.org/0000-0002-4258-9015","observed_orcids":["https://orcid.org/0000-0002-4258-9015"]},"institutions":[{"id":"https://openalex.org/I3132405765","display_name":"Mari State University","ror":"https://ror.org/01yjw8d43","country_code":"RU","type":"education","lineage":["https://openalex.org/I3132405765"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alena A. Semenova","raw_affiliation_strings":["Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia","institution_ids":["https://openalex.org/I3132405765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005664578","display_name":"Anna I. Ilzorkina","orcid":"https://orcid.org/0000-0001-9899-4979","observed_orcids":["https://orcid.org/0000-0001-9899-4979"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210088122","display_name":"Institute of Theoretical and Experimental Biophysics","ror":"https://ror.org/008ebms37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210088122","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anna I. Ilzorkina","raw_affiliation_strings":["Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210088122"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013548971","display_name":"Natalia Markelova","orcid":"https://orcid.org/0000-0002-7134-0729","observed_orcids":["https://orcid.org/0000-0002-7134-0729"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210155801","display_name":"Institute of Cell Biophysics","ror":"https://ror.org/05gbnpz65","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210155801"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Natalia Y. Markelova","raw_affiliation_strings":["Institute of Cell Biophysics, Russian Academy of Sciences, PSCBR RAS, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cell Biophysics, Russian Academy of Sciences, PSCBR RAS, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210155801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026253493","display_name":"Nikita V. Penkov","orcid":"https://orcid.org/0000-0003-2212-5640","observed_orcids":["https://orcid.org/0000-0003-2212-5640"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210155801","display_name":"Institute of Cell Biophysics","ror":"https://ror.org/05gbnpz65","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210155801"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Nikita V. Penkov","raw_affiliation_strings":["Institute of Cell Biophysics, Russian Academy of Sciences, PSCBR RAS, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia"],"raw_orcid":"https://orcid.org/0000-0003-2212-5640","affiliations":[{"raw_affiliation_string":"Institute of Cell Biophysics, Russian Academy of Sciences, PSCBR RAS, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210155801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004582230","display_name":"Elvira Rifovna Shakurova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210092861","display_name":"Institute of Catalysis and Petrochemistry","ror":"https://ror.org/00hfszj21","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210092861","https://openalex.org/I4210145551"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Elvira R. Shakurova","raw_affiliation_strings":["Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Prospekt Oktyabrya 141, Ufa, Republic of Bashkortostan, 450075, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Prospekt Oktyabrya 141, Ufa, Republic of Bashkortostan, 450075, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210092861"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062734581","display_name":"Konstantin N. Belosludtsev","orcid":"https://orcid.org/0000-0001-5392-7035","observed_orcids":["https://orcid.org/0000-0001-5392-7035"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I3132405765","display_name":"Mari State University","ror":"https://ror.org/01yjw8d43","country_code":"RU","type":"education","lineage":["https://openalex.org/I3132405765"]},{"id":"https://openalex.org/I4210088122","display_name":"Institute of Theoretical and Experimental Biophysics","ror":"https://ror.org/008ebms37","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210088122","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Konstantin N. Belosludtsev","raw_affiliation_strings":["Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia","Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia","Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I3132405765","https://openalex.org/I4210088122"]},{"raw_affiliation_string":"Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210088122"]},{"raw_affiliation_string":"Mari State University, pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia","institution_ids":["https://openalex.org/I3132405765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058309457","display_name":"Lyudmila Vyacheslavovna Parfenova","orcid":"https://orcid.org/0000-0003-2816-2178","observed_orcids":["https://orcid.org/0000-0003-2816-2178"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210092861","display_name":"Institute of Catalysis and Petrochemistry","ror":"https://ror.org/00hfszj21","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210092861","https://openalex.org/I4210145551"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Lyudmila V. Parfenova","raw_affiliation_strings":["Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Prospekt Oktyabrya 141, Ufa, Republic of Bashkortostan, 450075, Russia"],"raw_orcid":"https://orcid.org/0000-0003-2816-2178","affiliations":[{"raw_affiliation_string":"Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Prospekt Oktyabrya 141, Ufa, Republic of Bashkortostan, 450075, Russia","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210092861"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5037236045"],"corresponding_institution_ids":["https://openalex.org/I3132405765"],"apc_list":{"value":3310,"currency":"USD","value_usd":3310},"apc_paid":null,"fwci":1.2453,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.73981016,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"349","issue":null,"first_page":"109678","last_page":"109678"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9199000000953674,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9199000000953674,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.031199999153614044,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12356","display_name":"Bioactive Compounds and Antitumor Agents","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/betulin-derivatives","display_name":"betulin derivatives","score":0.7960000038146973},{"id":"https://openalex.org/keywords/liposome-permeabilization","display_name":"liposome permeabilization","score":0.9459999799728394},{"id":"https://openalex.org/keywords/sulforhodamine-b","display_name":"sulforhodamine B","score":0.8679999709129333},{"id":"https://openalex.org/keywords/mitochondrial-membrane-potential","display_name":"mitochondrial membrane potential","score":0.8330000042915344},{"id":"https://openalex.org/keywords/mitochondrial-swelling","display_name":"mitochondrial swelling","score":0.6669999957084656},{"id":"https://openalex.org/keywords/respiratory-chain-complexes","display_name":"respiratory chain complexes","score":0.5690000057220459},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.75},{"id":"https://openalex.org/keywords/lipophilicity","display_name":"lipophilicity","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C2780397019","wikidata":"https://www.wikidata.org/wiki/Q7252076","display_name":"Protonophore","level":3,"score":0.7813617587089539},{"id":"https://openalex.org/C2777221202","wikidata":"https://www.wikidata.org/wiki/Q2518436","display_name":"Pyridinium","level":2,"score":0.7764177322387695},{"id":"https://openalex.org/C2778509883","wikidata":"https://www.wikidata.org/wiki/Q419726","display_name":"Betulin","level":2,"score":0.7542563676834106},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.641115665435791},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.604918897151947},{"id":"https://openalex.org/C2776074239","wikidata":"https://www.wikidata.org/wiki/Q2452042","display_name":"Sulforhodamine B","level":4,"score":0.5974416136741638},{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.5917145013809204},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.5019066333770752},{"id":"https://openalex.org/C201399114","wikidata":"https://www.wikidata.org/wiki/Q898401","display_name":"Lipophilicity","level":2,"score":0.491702139377594},{"id":"https://openalex.org/C2779485729","wikidata":"https://www.wikidata.org/wiki/Q210385","display_name":"Pyridine","level":2,"score":0.4901209771633148},{"id":"https://openalex.org/C75385678","wikidata":"https://www.wikidata.org/wiki/Q4896390","display_name":"Inner mitochondrial membrane","level":3,"score":0.48119574785232544},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.4536364674568176},{"id":"https://openalex.org/C181911157","wikidata":"https://www.wikidata.org/wiki/Q389844","display_name":"Membrane potential","level":2,"score":0.45004260540008545},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.38857340812683105},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3736017346382141},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.35725563764572144},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.23005089163780212},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1955883800983429},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1643162965774536}],"mesh":[{"descriptor_ui":"D000094062","descriptor_name":"Betulinic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008930","descriptor_name":"Mitochondria, Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011725","descriptor_name":"Pyridines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013057","descriptor_name":"Spectrum Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.cbi.2021.109678","doi":"https://doi.org/10.1016/j.cbi.2021.109678","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cbi.2021.109678","pdf_url":null,"source":{"id":"https://openalex.org/S34460812","display_name":"Chemico-Biological Interactions","issn_l":"0009-2797","issn":["0009-2797","1872-7786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-Biological Interactions","raw_type":"journal-article"},{"id":"pmid:34600868","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34600868","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-biological interactions","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4453284491","display_name":null,"funder_award_id":"19-119022290012-3","funder_id":"https://openalex.org/F4320321079","funder_display_name":"Russian Foundation for Basic Research"},{"id":"https://openalex.org/G8449462786","display_name":null,"funder_award_id":"20-015-00124","funder_id":"https://openalex.org/F4320321079","funder_display_name":"Russian Foundation for Basic Research"}],"funders":[{"id":"https://openalex.org/F4320321079","display_name":"Russian Foundation for Basic Research","ror":"https://ror.org/02mh1ke95"},{"id":"https://openalex.org/F4320334801","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1542790225","https://openalex.org/W2000258771","https://openalex.org/W2007365051","https://openalex.org/W2020736186","https://openalex.org/W2029366527","https://openalex.org/W2034672527","https://openalex.org/W2051476652","https://openalex.org/W2059535893","https://openalex.org/W2078002817","https://openalex.org/W2089487461","https://openalex.org/W2101373754","https://openalex.org/W2108832317","https://openalex.org/W2409362704","https://openalex.org/W2414721313","https://openalex.org/W2593124711","https://openalex.org/W2610472521","https://openalex.org/W2756186562","https://openalex.org/W2802118311","https://openalex.org/W2903238319","https://openalex.org/W2904210229","https://openalex.org/W2933606749","https://openalex.org/W2946303440","https://openalex.org/W2954067180","https://openalex.org/W2955504961","https://openalex.org/W2996450204","https://openalex.org/W3016438962","https://openalex.org/W3032917335","https://openalex.org/W3044531785","https://openalex.org/W3149487008","https://openalex.org/W3155844788","https://openalex.org/W3161804418","https://openalex.org/W3165521089"],"related_works":["https://openalex.org/W1969704170","https://openalex.org/W7161830765","https://openalex.org/W4387853712","https://openalex.org/W3032917335","https://openalex.org/W2059214460","https://openalex.org/W2070563010","https://openalex.org/W2731789828","https://openalex.org/W1993543551","https://openalex.org/W2029379695","https://openalex.org/W3118025795"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-10-11T00:00:00"}