{"id":"https://openalex.org/W3204293397","doi":"https://doi.org/10.1055/s-0041-1735844","title":"Spontaneous Regression and Reoccurrence of Osteosarcoma in a Canine Tibia","display_name":"Spontaneous Regression and Reoccurrence of Osteosarcoma in a Canine Tibia","publication_year":2021,"publication_date":"2021-07-01","ids":{"openalex":"https://openalex.org/W3204293397","doi":"https://doi.org/10.1055/s-0041-1735844","mag":"3204293397"},"language":"en","primary_location":{"id":"doi:10.1055/s-0041-1735844","doi":"https://doi.org/10.1055/s-0041-1735844","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0041-1735844","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1735844.pdf","source":{"id":"https://openalex.org/S4210198751","display_name":"VCOT Open","issn_l":"2625-2325","issn":["2625-2325"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"VCOT Open","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1735844.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050261579","display_name":"Olivia Obringer","orcid":"https://orcid.org/0000-0002-7272-0432","observed_orcids":["https://orcid.org/0000-0002-7272-0432"]},"institutions":[{"id":"https://openalex.org/I4210107178","display_name":"University of Saint Francis","ror":"https://ror.org/01h6pze39","country_code":"US","type":"education","lineage":["https://openalex.org/I4210107178"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivia Obringer","raw_affiliation_strings":["University of Saint Francis, Fort Wayne, Indiana, United States"],"raw_orcid":"https://orcid.org/0000-0002-7272-0432","affiliations":[{"raw_affiliation_string":"University of Saint Francis, Fort Wayne, Indiana, United States","institution_ids":["https://openalex.org/I4210107178"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110806975","display_name":"Bradley R. Coolman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bradley Coolman","raw_affiliation_strings":["Northeast Indiana Veterinary Emergency & Specialty Hospital, Fort Wayne, Indiana, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Northeast Indiana Veterinary Emergency & Specialty Hospital, Fort Wayne, Indiana, United States","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005057467","display_name":"Jason T. Crawford","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jason Crawford","raw_affiliation_strings":["Inner-Pet Imaging, Huntertown, Indiana, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inner-Pet Imaging, Huntertown, Indiana, United States","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3007,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.54602226,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"04","issue":"02","first_page":"e86","last_page":"e91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/canine-osteosarcoma","display_name":"canine osteosarcoma","score":0.9449999928474426},{"id":"https://openalex.org/keywords/spontaneous-regression","display_name":"spontaneous regression","score":0.8410000205039978},{"id":"https://openalex.org/keywords/proximal-tibia","display_name":"proximal tibia","score":0.9089999794960022},{"id":"https://openalex.org/keywords/labrador-retriever","display_name":"Labrador Retriever","score":0.8130000233650208},{"id":"https://openalex.org/keywords/tibial-plateau-leveling-osteotomy","display_name":"tibial plateau leveling osteotomy","score":0.7639999985694885},{"id":"https://openalex.org/keywords/serial-biopsies","display_name":"serial biopsies","score":0.4869999885559082},{"id":"https://openalex.org/keywords/young-dogs","display_name":"young dogs","score":0.3700000047683716},{"id":"https://openalex.org/keywords/cranial-cruciate-ligament-rupture","display_name":"cranial cruciate ligament rupture","score":0.7490000128746033}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9281957149505615},{"id":"https://openalex.org/C2777760704","wikidata":"https://www.wikidata.org/wiki/Q549534","display_name":"Osteosarcoma","level":2,"score":0.7480813264846802},{"id":"https://openalex.org/C2777236700","wikidata":"https://www.wikidata.org/wiki/Q178366","display_name":"Tibia","level":2,"score":0.7240630984306335},{"id":"https://openalex.org/C36454342","wikidata":"https://www.wikidata.org/wiki/Q245341","display_name":"Radiography","level":2,"score":0.6894311904907227},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5478116273880005},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4546348452568054},{"id":"https://openalex.org/C2779771469","wikidata":"https://www.wikidata.org/wiki/Q1428918","display_name":"Lameness","level":2,"score":0.4421895146369934},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.38740378618240356},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11574628949165344}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-0041-1735844","doi":"https://doi.org/10.1055/s-0041-1735844","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0041-1735844","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1735844.pdf","source":{"id":"https://openalex.org/S4210198751","display_name":"VCOT Open","issn_l":"2625-2325","issn":["2625-2325"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"VCOT Open","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1055/s-0041-1735844","doi":"https://doi.org/10.1055/s-0041-1735844","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0041-1735844","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0041-1735844.pdf","source":{"id":"https://openalex.org/S4210198751","display_name":"VCOT Open","issn_l":"2625-2325","issn":["2625-2325"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"VCOT Open","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320309036","display_name":"Purdue University","ror":"https://ror.org/02dqehb95"},{"id":"https://openalex.org/F4320333545","display_name":"College of Veterinary Medicine, Purdue University","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3204293397.pdf","grobid_xml":"https://content.openalex.org/works/W3204293397.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W60586669","https://openalex.org/W130461636","https://openalex.org/W1544003086","https://openalex.org/W1558939305","https://openalex.org/W1844671708","https://openalex.org/W1973439836","https://openalex.org/W1974366983","https://openalex.org/W1977621771","https://openalex.org/W1985841941","https://openalex.org/W1991782447","https://openalex.org/W1994311424","https://openalex.org/W2037555056","https://openalex.org/W2048654423","https://openalex.org/W2070192320","https://openalex.org/W2070436392","https://openalex.org/W2073347833","https://openalex.org/W2081220530","https://openalex.org/W2083485224","https://openalex.org/W2088218337","https://openalex.org/W2088795544","https://openalex.org/W2101522258","https://openalex.org/W2111627245","https://openalex.org/W2150557440","https://openalex.org/W2169491449","https://openalex.org/W2170162095","https://openalex.org/W2260518232","https://openalex.org/W2344262879","https://openalex.org/W2414525941","https://openalex.org/W2469129388","https://openalex.org/W2581764773","https://openalex.org/W2597618526","https://openalex.org/W2903580081","https://openalex.org/W2970713591","https://openalex.org/W2974209461","https://openalex.org/W3083502324","https://openalex.org/W3142586697"],"related_works":["https://openalex.org/W2088218337","https://openalex.org/W4214501647","https://openalex.org/W3083502324","https://openalex.org/W2153697684","https://openalex.org/W1977621771","https://openalex.org/W2766101950","https://openalex.org/W3125524261","https://openalex.org/W2411098926","https://openalex.org/W2162787957","https://openalex.org/W2399414960"],"abstract_inverted_index":{"Abstract":[0],"A":[1],"32-month-old":[2],"female":[3],"Labrador":[4],"Retriever":[5],"mix-breed":[6],"presented":[7,80],"for":[8,46,81,131],"right":[9,98,136],"pelvic":[10],"limb":[11],"lameness":[12],"with":[13,27,121,211],"firm":[14],"swelling":[15,133],"on":[16,39,92],"the":[17,21,31,35,56,61,78,93,97,102,105,128,135,151,166,177,198,205,221],"lateral":[18,32,94],"aspect":[19,95],"of":[20,34,96,104,150,180,197,230],"stifle.":[22],"Radiographs":[23,86,139],"revealed":[24,87,140],"a":[25,40,88,184],"mass":[26],"periosteal":[28],"elevation":[29],"along":[30],"cortex":[33],"proximal":[36,99,152],"tibia.":[37,138,153],"Histology":[38],"core":[41,158],"biopsy":[42],"sample":[43],"was":[44,50,58,119,155,168],"diagnostic":[45],"osteosarcoma.":[47,107],"Surgical":[48],"treatment":[49],"declined.":[51],"Eight":[52],"months":[53,74,125,171,191],"post":[54],"diagnosis,":[55],"patient":[57,79,109,129,167,209],"re-evaluated":[59],"by":[60,220],"primary":[62],"care":[63],"veterinarian":[64],"and":[65,147,165,217,225],"had":[66],"no":[67],"lameness,":[68],"pain,":[69],"or":[70],"tibial":[71,112],"swelling.":[72],"Sixty-three":[73],"later":[75],"(5.2":[76],"years),":[77],"cranial":[82],"cruciate":[83],"ligament":[84],"ruptures.":[85],"smooth":[89],"bony":[90],"protuberance":[91],"tibia":[100],"in":[101,183,204],"area":[103],"previous":[106],"The":[108,116,160],"underwent":[110],"bilateral":[111],"plateau":[113],"levelling":[114],"osteotomies.":[115],"surgical":[117],"recovery":[118],"uneventful":[120],"normal":[122],"healing.":[123],"Twenty-seven":[124],"following":[126],"surgery,":[127],"returned":[130],"painful":[132],"around":[134],"proximolateral":[137],"an":[141,181],"8":[142],"\u00d7":[143],"9":[144],"cm":[145],"osteoproliferative":[146],"osteolytic":[148],"lesion":[149],"Osteosarcoma":[154],"confirmed":[156],"via":[157],"biopsy.":[159],"bone":[161],"tumour":[162],"grew":[163],"rapidly,":[164],"euthanatized":[169],"3":[170],"thereafter.":[172],"This":[173],"case":[174,232],"report":[175],"demonstrates":[176],"unusual":[178],"occurrence":[179],"osteosarcoma":[182,201],"young":[185],"dog":[186],"which":[187],"spontaneously":[188],"regressed.":[189],"Ninety":[190],"(7.5":[192],"years)":[193],"after":[194],"clinical":[195,213],"resolution":[196],"initial":[199],"tumour,":[200],"formed":[202],"again":[203],"same":[206,222],"location.":[207],"Lifetime":[208],"monitoring":[210],"repeated":[212],"exams,":[214],"serial":[215],"radiographs,":[216],"multiple":[218],"biopsies":[219],"surgeon,":[223],"pathologists,":[224],"radiologist":[226],"are":[227],"unique":[228],"features":[229],"this":[231],"report.":[233]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2021-10-11T00:00:00"}
