{"id":"https://openalex.org/W3204024682","doi":"https://doi.org/10.3390/polym13193307","title":"Application of Non-Viral Vectors in Drug Delivery and Gene Therapy","display_name":"Application of Non-Viral Vectors in Drug Delivery and Gene Therapy","publication_year":2021,"publication_date":"2021-09-28","ids":{"openalex":"https://openalex.org/W3204024682","doi":"https://doi.org/10.3390/polym13193307","mag":"3204024682","pmid":"https://pubmed.ncbi.nlm.nih.gov/34641123","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8512075"},"language":"en","primary_location":{"id":"doi:10.3390/polym13193307","doi":"https://doi.org/10.3390/polym13193307","is_oa":true,"landing_page_url":"https://doi.org/10.3390/polym13193307","pdf_url":"https://www.mdpi.com/2073-4360/13/19/3307/pdf?version=1632809569","source":{"id":"https://openalex.org/S123288148","display_name":"Polymers","issn_l":"2073-4360","issn":["2073-4360"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polymers","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2073-4360/13/19/3307/pdf?version=1632809569","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019448267","display_name":"Shuaikai Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuaikai Ren","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100619579","display_name":"Mengjie Wang","orcid":"https://orcid.org/0000-0003-3637-4787","observed_orcids":["https://orcid.org/0000-0003-3637-4787"]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengjie Wang","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101931990","display_name":"Chunxin Wang","orcid":"https://orcid.org/0000-0003-3692-4558","observed_orcids":["https://orcid.org/0000-0003-3692-4558"]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunxin Wang","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100322574","display_name":"Yan Wang","orcid":"https://orcid.org/0000-0001-9786-7492","observed_orcids":["https://orcid.org/0000-0001-9786-7492"]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Wang","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024670449","display_name":"Changjiao Sun","orcid":"https://orcid.org/0000-0002-8246-1526","observed_orcids":["https://orcid.org/0000-0002-8246-1526"]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changjiao Sun","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017500461","display_name":"Zhanghua Zeng","orcid":"https://orcid.org/0000-0002-8102-4770","observed_orcids":["https://orcid.org/0000-0002-8102-4770"]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhanghua Zeng","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":"https://orcid.org/0000-0002-8102-4770","affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002807965","display_name":"Haixin Cui","orcid":"https://orcid.org/0000-0002-1274-1987","observed_orcids":["https://orcid.org/0000-0002-1274-1987"]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haixin Cui","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100619169","display_name":"Xiang Zhao","orcid":"https://orcid.org/0000-0002-6809-6542","observed_orcids":["https://orcid.org/0000-0002-6809-6542"]},"institutions":[{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210143868","display_name":"Institute of Environment and Sustainable Development in Agriculture","ror":"https://ror.org/048nm8g63","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210143868","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiang Zhao","raw_affiliation_strings":["Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China","institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100619169"],"corresponding_institution_ids":["https://openalex.org/I4210138501","https://openalex.org/I4210143868"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2376},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2376},"fwci":0.5987,"has_fulltext":true,"cited_by_count":69,"citation_normalized_percentile":{"value":0.49194729,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"13","issue":"19","first_page":"3307","last_page":"3307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.7445999979972839,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.7445999979972839,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.22859999537467957,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.02250000089406967,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-viral-vectors","display_name":"non-viral vectors","score":0.9980000257492065},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.8939999938011169},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/liposomes","display_name":"liposomes","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gold-nanoparticles","display_name":"gold nanoparticles","score":1.0},{"id":"https://openalex.org/keywords/mesoporous-silica-nanoparticles","display_name":"mesoporous silica nanoparticles","score":1.0},{"id":"https://openalex.org/keywords/carbon-nanotubes","display_name":"carbon nanotubes","score":1.0},{"id":"https://openalex.org/keywords/targeted-delivery","display_name":"targeted delivery","score":0.7300000190734863},{"id":"https://openalex.org/keywords/circulation-time","display_name":"circulation time","score":0.625},{"id":"https://openalex.org/keywords/functional-modification","display_name":"functional modification","score":0.5910000205039978},{"id":"https://openalex.org/keywords/vector-synthesis","display_name":"vector synthesis","score":0.5929999947547913}],"concepts":[{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6124885082244873},{"id":"https://openalex.org/C135983454","wikidata":"https://www.wikidata.org/wiki/Q2790163","display_name":"Gene delivery","level":4,"score":0.6101994514465332},{"id":"https://openalex.org/C32470452","wikidata":"https://www.wikidata.org/wiki/Q2298489","display_name":"Viral vector","level":4,"score":0.5999441146850586},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5440115928649902},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.5193101763725281},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.5079203248023987},{"id":"https://openalex.org/C92087593","wikidata":"https://www.wikidata.org/wiki/Q427389","display_name":"Vector (molecular biology)","level":4,"score":0.46633243560791016},{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.45979732275009155},{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.45412933826446533},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3339158892631531},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.332191526889801},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2520228624343872},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.20480898022651672},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19692540168762207},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13895100355148315},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1064797043800354},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.06972452998161316},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/polym13193307","doi":"https://doi.org/10.3390/polym13193307","is_oa":true,"landing_page_url":"https://doi.org/10.3390/polym13193307","pdf_url":"https://www.mdpi.com/2073-4360/13/19/3307/pdf?version=1632809569","source":{"id":"https://openalex.org/S123288148","display_name":"Polymers","issn_l":"2073-4360","issn":["2073-4360"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polymers","raw_type":"journal-article"},{"id":"pmid:34641123","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34641123","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polymers","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8512075","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8512075/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polymers (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:e97d81cece4343f6b52cbdd01af514b0","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/e97d81cece4343f6b52cbdd01af514b0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Polymers, Vol 13, Iss 19, p 3307 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/polym13193307","doi":"https://doi.org/10.3390/polym13193307","is_oa":true,"landing_page_url":"https://doi.org/10.3390/polym13193307","pdf_url":"https://www.mdpi.com/2073-4360/13/19/3307/pdf?version=1632809569","source":{"id":"https://openalex.org/S123288148","display_name":"Polymers","issn_l":"2073-4360","issn":["2073-4360"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polymers","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1427533770","display_name":null,"funder_award_id":"2017YFD0500900","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G4271130387","display_name":null,"funder_award_id":"CAASZDRW202008","funder_id":"https://openalex.org/F4320335848","funder_display_name":"Agricultural Science and Technology Innovation Program"},{"id":"https://openalex.org/G5552572830","display_name":null,"funder_award_id":"CAAS-ZDRW202008","funder_id":"https://openalex.org/F4320323155","funder_display_name":"Chinese Academy of Agricultural Sciences"},{"id":"https://openalex.org/G6944604227","display_name":null,"funder_award_id":"ZDRW202008","funder_id":"https://openalex.org/F4320323155","funder_display_name":"Chinese Academy of Agricultural Sciences"}],"funders":[{"id":"https://openalex.org/F4320323155","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320335848","display_name":"Agricultural Science and Technology Innovation Program","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3204024682.pdf","grobid_xml":"https://content.openalex.org/works/W3204024682.grobid-xml"},"referenced_works_count":302,"referenced_works":["https://openalex.org/W3011556","https://openalex.org/W257094742","https://openalex.org/W1249211334","https://openalex.org/W1483024467","https://openalex.org/W1517618522","https://openalex.org/W1526894457","https://openalex.org/W1564553363","https://openalex.org/W1606853210","https://openalex.org/W1710257910","https://openalex.org/W1713371841","https://openalex.org/W1751608847","https://openalex.org/W1874838347","https://openalex.org/W1966237056","https://openalex.org/W1968044889","https://openalex.org/W1971734589","https://openalex.org/W1973260880","https://openalex.org/W1973998725","https://openalex.org/W1975493559","https://openalex.org/W1976675331","https://openalex.org/W1977150737","https://openalex.org/W1982784029","https://openalex.org/W1985247850","https://openalex.org/W1986764585","https://openalex.org/W1987995270","https://openalex.org/W1988193392","https://openalex.org/W1989558185","https://openalex.org/W1991720510","https://openalex.org/W1995098796","https://openalex.org/W1998346656","https://openalex.org/W1998870247","https://openalex.org/W2000568918","https://openalex.org/W2003001975","https://openalex.org/W2003108709","https://openalex.org/W2006687009","https://openalex.org/W2008588146","https://openalex.org/W2008644802","https://openalex.org/W2010655741","https://openalex.org/W2014356856","https://openalex.org/W2018664696","https://openalex.org/W2018858346","https://openalex.org/W2019613864","https://openalex.org/W2022058170","https://openalex.org/W2027411673","https://openalex.org/W2029697829","https://openalex.org/W2039030515","https://openalex.org/W2040242857","https://openalex.org/W2042413537","https://openalex.org/W2042602209","https://openalex.org/W2043933297","https://openalex.org/W2046772999","https://openalex.org/W2048056641","https://openalex.org/W2049425569","https://openalex.org/W2051187578","https://openalex.org/W2051925512","https://openalex.org/W2052094703","https://openalex.org/W2052256056","https://openalex.org/W2053847207","https://openalex.org/W2054454981","https://openalex.org/W2056180004","https://openalex.org/W2056219450","https://openalex.org/W2057256078","https://openalex.org/W2058022874","https://openalex.org/W2059083179","https://openalex.org/W2061510929","https://openalex.org/W2065362813","https://openalex.org/W2067273125","https://openalex.org/W2069414163","https://openalex.org/W2070515852","https://openalex.org/W2071719941","https://openalex.org/W2072986171","https://openalex.org/W2076855170","https://openalex.org/W2077228161","https://openalex.org/W2080650826","https://openalex.org/W2082990150","https://openalex.org/W2083529683","https://openalex.org/W2084252835","https://openalex.org/W2085516892","https://openalex.org/W2085993775","https://openalex.org/W2086664688","https://openalex.org/W2093271202","https://openalex.org/W2094963548","https://openalex.org/W2097603366","https://openalex.org/W2100026459","https://openalex.org/W2102494473","https://openalex.org/W2103768828","https://openalex.org/W2104166274","https://openalex.org/W2111318497","https://openalex.org/W2111442204","https://openalex.org/W2115029038","https://openalex.org/W2118208632","https://openalex.org/W2124030287","https://openalex.org/W2127342759","https://openalex.org/W2128364082","https://openalex.org/W2130586100","https://openalex.org/W2130886644","https://openalex.org/W2134451967","https://openalex.org/W2134605987","https://openalex.org/W2134934754","https://openalex.org/W2136510151","https://openalex.org/W2143856400","https://openalex.org/W2147976539","https://openalex.org/W2148145619","https://openalex.org/W2151671351","https://openalex.org/W2151755258","https://openalex.org/W2158096961","https://openalex.org/W2159265947","https://openalex.org/W2161279046","https://openalex.org/W2165398062","https://openalex.org/W2166863655","https://openalex.org/W2170704158","https://openalex.org/W2186579299","https://openalex.org/W2188996997","https://openalex.org/W2190647635","https://openalex.org/W2197053162","https://openalex.org/W2214752215","https://openalex.org/W2220830975","https://openalex.org/W2232715309","https://openalex.org/W2260790197","https://openalex.org/W2286566069","https://openalex.org/W2287736109","https://openalex.org/W2296051580","https://openalex.org/W2297815823","https://openalex.org/W2297843906","https://openalex.org/W2314102813","https://openalex.org/W2315111660","https://openalex.org/W2329372091","https://openalex.org/W2329451496","https://openalex.org/W2334074570","https://openalex.org/W2336139095","https://openalex.org/W2340872764","https://openalex.org/W2343712942","https://openalex.org/W2345549585","https://openalex.org/W2346372219","https://openalex.org/W2396951023","https://openalex.org/W2397493970","https://openalex.org/W2405595888","https://openalex.org/W2411153062","https://openalex.org/W2466620019","https://openalex.org/W2468547588","https://openalex.org/W2487808430","https://openalex.org/W2511134167","https://openalex.org/W2511706330","https://openalex.org/W2520550985","https://openalex.org/W2522376819","https://openalex.org/W2526204558","https://openalex.org/W2527851797","https://openalex.org/W2570365827","https://openalex.org/W2578623881","https://openalex.org/W2581051743","https://openalex.org/W2581524809","https://openalex.org/W2583134197","https://openalex.org/W2591025507","https://openalex.org/W2594262749","https://openalex.org/W2594298040","https://openalex.org/W2595814027","https://openalex.org/W2597298911","https://openalex.org/W2599276599","https://openalex.org/W2599603205","https://openalex.org/W2600891355","https://openalex.org/W2604906306","https://openalex.org/W2607114305","https://openalex.org/W2614154488","https://openalex.org/W2617795727","https://openalex.org/W2620315774","https://openalex.org/W2620539488","https://openalex.org/W2626389078","https://openalex.org/W2630579787","https://openalex.org/W2691085783","https://openalex.org/W2724193338","https://openalex.org/W2736558325","https://openalex.org/W2739463248","https://openalex.org/W2742806160","https://openalex.org/W2744199567","https://openalex.org/W2744658185","https://openalex.org/W2749722012","https://openalex.org/W2752960590","https://openalex.org/W2754738099","https://openalex.org/W2754831689","https://openalex.org/W2758072820","https://openalex.org/W2766483307","https://openalex.org/W2766534764","https://openalex.org/W2767008132","https://openalex.org/W2767819361","https://openalex.org/W2770284128","https://openalex.org/W2777476002","https://openalex.org/W2778806019","https://openalex.org/W2780326442","https://openalex.org/W2783155489","https://openalex.org/W2783305268","https://openalex.org/W2783580099","https://openalex.org/W2790083519","https://openalex.org/W2791506231","https://openalex.org/W2791841262","https://openalex.org/W2793069595","https://openalex.org/W2794370011","https://openalex.org/W2794442641","https://openalex.org/W2799767959","https://openalex.org/W2800208003","https://openalex.org/W2801513916","https://openalex.org/W2801589383","https://openalex.org/W2802060782","https://openalex.org/W2802528557","https://openalex.org/W2804647561","https://openalex.org/W2805076914","https://openalex.org/W2809845028","https://openalex.org/W2810634892","https://openalex.org/W2859146093","https://openalex.org/W2884445981","https://openalex.org/W2888661637","https://openalex.org/W2888722019","https://openalex.org/W2888975303","https://openalex.org/W2888977069","https://openalex.org/W2890055837","https://openalex.org/W2892405094","https://openalex.org/W2892651454","https://openalex.org/W2894874252","https://openalex.org/W2895242129","https://openalex.org/W2895334061","https://openalex.org/W2896290579","https://openalex.org/W2901816172","https://openalex.org/W2908564203","https://openalex.org/W2910496811","https://openalex.org/W2911499655","https://openalex.org/W2914162332","https://openalex.org/W2914654775","https://openalex.org/W2914728548","https://openalex.org/W2914937413","https://openalex.org/W2915312833","https://openalex.org/W2915542701","https://openalex.org/W2941289539","https://openalex.org/W2941622614","https://openalex.org/W2942110717","https://openalex.org/W2942446910","https://openalex.org/W2943113626","https://openalex.org/W2945662689","https://openalex.org/W2958372702","https://openalex.org/W2963681439","https://openalex.org/W2967436081","https://openalex.org/W2969245112","https://openalex.org/W2969470555","https://openalex.org/W2969594404","https://openalex.org/W2969800877","https://openalex.org/W2971871465","https://openalex.org/W2971932923","https://openalex.org/W2978313489","https://openalex.org/W2979355086","https://openalex.org/W2980610937","https://openalex.org/W2981028410","https://openalex.org/W2981489772","https://openalex.org/W2990668306","https://openalex.org/W2992975786","https://openalex.org/W2995215192","https://openalex.org/W2996219663","https://openalex.org/W2998507171","https://openalex.org/W2998705080","https://openalex.org/W2999887582","https://openalex.org/W3003667983","https://openalex.org/W3007796728","https://openalex.org/W3008326899","https://openalex.org/W3012414406","https://openalex.org/W3018153752","https://openalex.org/W3021823482","https://openalex.org/W3025022028","https://openalex.org/W3025154575","https://openalex.org/W3031993276","https://openalex.org/W3034563742","https://openalex.org/W3037415087","https://openalex.org/W3041449925","https://openalex.org/W3042028687","https://openalex.org/W3042472695","https://openalex.org/W3044226803","https://openalex.org/W3046285154","https://openalex.org/W3047252592","https://openalex.org/W3047903668","https://openalex.org/W3080319797","https://openalex.org/W3091711923","https://openalex.org/W3093565903","https://openalex.org/W3096086014","https://openalex.org/W3106918968","https://openalex.org/W3108272450","https://openalex.org/W3109320387","https://openalex.org/W3110847401","https://openalex.org/W3110951364","https://openalex.org/W3112666381","https://openalex.org/W3115887117","https://openalex.org/W3123395907","https://openalex.org/W3124778945","https://openalex.org/W3126562527","https://openalex.org/W3127391245","https://openalex.org/W3132171505","https://openalex.org/W3133605460","https://openalex.org/W3138720185","https://openalex.org/W3148240069","https://openalex.org/W3154675779","https://openalex.org/W3159608524","https://openalex.org/W3163672404","https://openalex.org/W3164228458","https://openalex.org/W3165545806","https://openalex.org/W3168529335","https://openalex.org/W3186306254","https://openalex.org/W3192160158","https://openalex.org/W6686770711"],"related_works":["https://openalex.org/W4385952061","https://openalex.org/W4296691782","https://openalex.org/W300740959","https://openalex.org/W4375858580","https://openalex.org/W2357129180","https://openalex.org/W4413776546","https://openalex.org/W7155693440","https://openalex.org/W2810728624","https://openalex.org/W596991943","https://openalex.org/W3091665211"],"abstract_inverted_index":{"Vectors":[0],"and":[1,10,18,32,34,47,57,70,89,112],"carriers":[2,48],"play":[3],"an":[4],"indispensable":[5],"role":[6],"in":[7,20,116],"gene":[8],"therapy":[9],"drug":[11],"delivery.":[12,92],"Non-viral":[13],"vectors":[14,46,75],"are":[15],"widely":[16],"developed":[17],"applied":[19],"clinical":[21],"practice":[22],"due":[23],"to":[24],"their":[25,128],"low":[26,35],"immunogenicity,":[27],"good":[28],"biocompatibility,":[29],"easy":[30],"synthesis":[31,66,101],"modification,":[33],"cost":[36],"of":[37,44,63,80,99,119],"production.":[38],"This":[39],"review":[40],"summarized":[41],"a":[42,124],"variety":[43],"non-viral":[45,74,120],"including":[49],"polymers,":[50],"liposomes,":[51],"gold":[52],"nanoparticles,":[53],"mesoporous":[54],"silica":[55],"nanoparticles":[56],"carbon":[58],"nanotubes":[59],"from":[60],"the":[61,78,83,110,117],"aspects":[62],"physicochemical":[64],"characteristics,":[65],"methods,":[67],"functional":[68],"modifications,":[69],"research":[71,114],"applications.":[72,130],"Notably,":[73],"can":[76],"enhance":[77],"absorption":[79],"cargos,":[81],"prolong":[82],"circulation":[84],"time,":[85],"improve":[86],"therapeutic":[87],"effects,":[88],"provide":[90],"targeted":[91],"Additional":[93],"studies":[94],"focused":[95],"on":[96,109],"recent":[97],"innovation":[98],"novel":[100],"techniques":[102],"for":[103,127],"vector":[104],"materials.":[105],"We":[106],"also":[107],"elaborated":[108],"problems":[111],"future":[113],"directions":[115],"development":[118],"vectors,":[121],"which":[122],"provided":[123],"theoretical":[125],"basis":[126],"broad":[129]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":10}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-10-11T00:00:00"}