{"id":"https://openalex.org/W3203709552","doi":"https://doi.org/10.3390/pharmaceutics13101595","title":"Novel Nanocombinations of l-Tryptophan and l-Cysteine: Preparation, Characterization, and Their Applications for Antimicrobial and Anticancer Activities","display_name":"Novel Nanocombinations of l-Tryptophan and l-Cysteine: Preparation, Characterization, and Their Applications for Antimicrobial and Anticancer Activities","publication_year":2021,"publication_date":"2021-10-01","ids":{"openalex":"https://openalex.org/W3203709552","doi":"https://doi.org/10.3390/pharmaceutics13101595","mag":"3203709552","pmid":"https://pubmed.ncbi.nlm.nih.gov/34683888","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8540933"},"language":"en","primary_location":{"id":"doi:10.3390/pharmaceutics13101595","doi":"https://doi.org/10.3390/pharmaceutics13101595","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics13101595","pdf_url":"https://www.mdpi.com/1999-4923/13/10/1595/pdf?version=1634517703","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1999-4923/13/10/1595/pdf?version=1634517703","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063817116","display_name":"Ahmed Ibrahim Abd-Elhamid","orcid":"https://orcid.org/0000-0002-8593-8713","observed_orcids":["https://orcid.org/0000-0002-8593-8713"]},"institutions":[{"id":"https://openalex.org/I4210101365","display_name":"City of Scientific Research and Technological Applications","ror":"https://ror.org/00pft3n23","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210101365"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ahmed I. Abd-Elhamid","raw_affiliation_strings":["City of Scientific Research and Technological Applications (SRTA- City), New Borg EL Arab","Composites and Nanostructured Materials Research Department, Advanced Technology and New Materials Research Institute, City of Scientific Research and Technological Applications (SRTA City), New Borg El-Arab 21934, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"City of Scientific Research and Technological Applications (SRTA- City), New Borg EL Arab","institution_ids":["https://openalex.org/I4210101365"]},{"raw_affiliation_string":"Composites and Nanostructured Materials Research Department, Advanced Technology and New Materials Research Institute, City of Scientific Research and Technological Applications (SRTA City), New Borg El-Arab 21934, Egypt","institution_ids":["https://openalex.org/I4210101365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057354034","display_name":"Hamada El\u2010Gendi","orcid":"https://orcid.org/0000-0003-0960-0048","observed_orcids":["https://orcid.org/0000-0003-0960-0048"]},"institutions":[{"id":"https://openalex.org/I4210101365","display_name":"City of Scientific Research and Technological Applications","ror":"https://ror.org/00pft3n23","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210101365"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Hamada El-Gendi","raw_affiliation_strings":["City of Scientific Research and Technological Applications (SRTA- City), New Borg EL Arab","Bioprocess Development Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA City), New Borg El-Arab 21934, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"City of Scientific Research and Technological Applications (SRTA- City), New Borg EL Arab","institution_ids":["https://openalex.org/I4210101365"]},{"raw_affiliation_string":"Bioprocess Development Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA City), New Borg El-Arab 21934, Egypt","institution_ids":["https://openalex.org/I4210101365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023031083","display_name":"Abdallah E. Abdallah","orcid":"https://orcid.org/0000-0003-2597-7419","observed_orcids":["https://orcid.org/0000-0003-2597-7419"]},"institutions":[{"id":"https://openalex.org/I184834183","display_name":"Al-Azhar University","ror":"https://ror.org/05fnp1145","country_code":"EG","type":"education","lineage":["https://openalex.org/I184834183"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Abdallah E. Abdallah","raw_affiliation_strings":["Al-Azhar University","Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Al-Azhar University","institution_ids":["https://openalex.org/I184834183"]},{"raw_affiliation_string":"Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt","institution_ids":["https://openalex.org/I184834183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025470334","display_name":"Esmail M. El\u2010Fakharany","orcid":"https://orcid.org/0000-0002-0724-8477","observed_orcids":["https://orcid.org/0000-0002-0724-8477"]},"institutions":[{"id":"https://openalex.org/I4210101365","display_name":"City of Scientific Research and Technological Applications","ror":"https://ror.org/00pft3n23","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210101365"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Esmail El-Fakharany","raw_affiliation_strings":["City of Scientific Research and Technological Applications (SRTA- City), New Borg EL Arab","Protein Research Department, Genetic Engineering and Biotechnology Research Institute GEBRI, City of Scientific Research and Technological Applications (SRTA City), New Borg El-Arab 21934, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"City of Scientific Research and Technological Applications (SRTA- City), New Borg EL Arab","institution_ids":["https://openalex.org/I4210101365"]},{"raw_affiliation_string":"Protein Research Department, Genetic Engineering and Biotechnology Research Institute GEBRI, City of Scientific Research and Technological Applications (SRTA City), New Borg El-Arab 21934, Egypt","institution_ids":["https://openalex.org/I4210101365"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5025470334"],"corresponding_institution_ids":["https://openalex.org/I4210101365"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2376},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2376},"fwci":1.2788,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.76653933,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"13","issue":"10","first_page":"1595","last_page":"1595"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.8500999808311462,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.8500999808311462,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11128","display_name":"Transition Metal Oxide Nanomaterials","score":0.033399999141693115,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.01640000008046627,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tungsten-oxide-nanoparticles","display_name":"tungsten oxide nanoparticles","score":0.9850000143051147},{"id":"https://openalex.org/keywords/wo3-nanosheets","display_name":"WO3 nanosheets","score":0.9480000138282776},{"id":"https://openalex.org/keywords/tryptophan","display_name":"tryptophan","score":0.9380000233650208},{"id":"https://openalex.org/keywords/cysteine","display_name":"cysteine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/amino-acid-functionalization","display_name":"amino acid functionalization","score":0.8949999809265137},{"id":"https://openalex.org/keywords/dye-removal","display_name":"dye removal","score":0.7129999995231628},{"id":"https://openalex.org/keywords/methylene-blue","display_name":"methylene blue","score":0.9750000238418579},{"id":"https://openalex.org/keywords/safranin","display_name":"safranin","score":0.9779999852180481},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9800000190734863},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":0.996999979019165},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9929999709129333},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9779999852180481},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.8379999995231628},{"id":"https://openalex.org/keywords/hepg2-cells","display_name":"HepG2 cells","score":0.8349999785423279},{"id":"https://openalex.org/keywords/caco-2-cells","display_name":"Caco-2 cells","score":0.9179999828338623},{"id":"https://openalex.org/keywords/p53-gene-expression","display_name":"p53 gene expression","score":0.6980000138282776},{"id":"https://openalex.org/keywords/e2f2","display_name":"E2F2","score":0.9169999957084656},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.9950000047683716},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.6740000247955322},{"id":"https://openalex.org/keywords/acid-rain","display_name":"acid rain","score":0.5559999942779541},{"id":"https://openalex.org/keywords/cation-exchange","display_name":"cation exchange","score":0.968999981880188}],"concepts":[{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.8289042115211487},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6138393878936768},{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.5865461826324463},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.5654337406158447},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3586638569831848},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2345564365386963},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.17031574249267578},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.15258383750915527},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/pharmaceutics13101595","doi":"https://doi.org/10.3390/pharmaceutics13101595","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics13101595","pdf_url":"https://www.mdpi.com/1999-4923/13/10/1595/pdf?version=1634517703","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-650889/v1","doi":"https://doi.org/10.21203/rs.3.rs-650889/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-650889/v1","pdf_url":"https://www.researchsquare.com/article/rs-650889/v1.pdf?c=1631899547000","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:7429050","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8540933","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:34683888","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34683888","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8540933","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8540933/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:322e410c7ac541f4a43c1dd1ca0330fb","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/322e410c7ac541f4a43c1dd1ca0330fb","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutics, Vol 13, Iss 10, p 1595 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/pharmaceutics13101595","doi":"https://doi.org/10.3390/pharmaceutics13101595","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics13101595","pdf_url":"https://www.mdpi.com/1999-4923/13/10/1595/pdf?version=1634517703","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3203709552.pdf","grobid_xml":"https://content.openalex.org/works/W3203709552.grobid-xml"},"referenced_works_count":76,"referenced_works":["https://openalex.org/W205637700","https://openalex.org/W371399941","https://openalex.org/W1788301610","https://openalex.org/W1829086185","https://openalex.org/W1848835470","https://openalex.org/W1964937304","https://openalex.org/W1977671139","https://openalex.org/W1987488259","https://openalex.org/W1988065839","https://openalex.org/W1991474651","https://openalex.org/W1992414720","https://openalex.org/W2002065777","https://openalex.org/W2010112859","https://openalex.org/W2010488407","https://openalex.org/W2010818369","https://openalex.org/W2012135172","https://openalex.org/W2019671154","https://openalex.org/W2033052785","https://openalex.org/W2039618696","https://openalex.org/W2046670862","https://openalex.org/W2054981131","https://openalex.org/W2055932031","https://openalex.org/W2065083595","https://openalex.org/W2078161107","https://openalex.org/W2084465048","https://openalex.org/W2085310162","https://openalex.org/W2094374892","https://openalex.org/W2117665793","https://openalex.org/W2124688926","https://openalex.org/W2131218102","https://openalex.org/W2155697357","https://openalex.org/W2180721764","https://openalex.org/W2333066538","https://openalex.org/W2411307169","https://openalex.org/W2470757888","https://openalex.org/W2472183064","https://openalex.org/W2513474680","https://openalex.org/W2534270080","https://openalex.org/W2739166107","https://openalex.org/W2755675499","https://openalex.org/W2768534399","https://openalex.org/W2782251525","https://openalex.org/W2787552541","https://openalex.org/W2800324465","https://openalex.org/W2897440342","https://openalex.org/W2905130778","https://openalex.org/W2905631420","https://openalex.org/W2920999641","https://openalex.org/W2952306610","https://openalex.org/W2955929219","https://openalex.org/W2966910054","https://openalex.org/W2972415461","https://openalex.org/W2981090081","https://openalex.org/W2983654700","https://openalex.org/W2990608745","https://openalex.org/W2999417355","https://openalex.org/W3000305694","https://openalex.org/W3003747078","https://openalex.org/W3008930735","https://openalex.org/W3012418430","https://openalex.org/W3031177352","https://openalex.org/W3032353527","https://openalex.org/W3034814173","https://openalex.org/W3034887984","https://openalex.org/W3045211841","https://openalex.org/W3091268816","https://openalex.org/W3104825229","https://openalex.org/W3107863414","https://openalex.org/W3119837063","https://openalex.org/W3126486277","https://openalex.org/W4206571807","https://openalex.org/W4238325563","https://openalex.org/W4238338122","https://openalex.org/W4248619803","https://openalex.org/W6637858733","https://openalex.org/W6715348735"],"related_works":["https://openalex.org/W3173810787","https://openalex.org/W4313585579","https://openalex.org/W4409628206","https://openalex.org/W4392751658","https://openalex.org/W4399275593","https://openalex.org/W4360835586","https://openalex.org/W2768930347","https://openalex.org/W4376279820","https://openalex.org/W2567084270","https://openalex.org/W2054513437"],"abstract_inverted_index":{"Tungsten":[0],"oxide":[1],"WO3":[2,30,66],"nanoparticles":[3],"(NPs)":[4],"were":[5,176],"prepared":[6,80],"in":[7,17,61,153,200,234,246],"a":[8,24,150,154],"form":[9],"of":[10,37,65,127,137,171,196,222,242],"nanosheets":[11],"with":[12,35,95,118,157,183,231],"homogeneous":[13],"size":[14],"and":[15,48,55,82,92,104,115,131,143,163,173,186,240],"dimensions":[16],"one":[18,36],"step":[19],"through":[20],"acid":[21,72],"precipitation":[22],"using":[23],"cation":[25],"exchange":[26],"column.":[27],"The":[28,79,168,216],"resulting":[29],"nanosheet":[31],"surface":[32],"was":[33,68,204],"decorated":[34],"the":[38,62,76,128,197,220,228],"two":[39],"amino":[40,71],"acids":[41],"(AAs)":[42],"l-tryptophan":[43],"(Trp)":[44],"or":[45],"l-cysteine":[46],"(Cys)":[47],"evaluated":[49],"for":[50],"their":[51],"dye":[52,86,97],"removal,":[53],"antimicrobial,":[54],"antitumor":[56],"activities.":[57],"A":[58],"noticeable":[59],"improvement":[60],"biological":[63],"activity":[64,88,111,121],"NPs":[67,106,133,188,224],"detected":[69],"upon":[70],"modification":[73],"compared":[74,212],"to":[75,160,178,213,225,227,236],"original":[77],"WO3.":[78],"WO3-Trp":[81,105,132,187],"WO3-Cys":[83,103,130,185],"exhibited":[84],"strong":[85,119],"removal":[87,98],"toward":[89,112,122],"methylene":[90],"blue":[91],"safranin":[93],"dyes":[94],"complete":[96],"(100%)":[99],"after":[100,181,206],"6":[101],"h.":[102],"revealed":[107],"higher":[108],"broad-spectrum":[109],"antibacterial":[110],"both":[113,184,223],"Gram-negative":[114],"Gram-positive":[116],"bacteria,":[117],"antifungal":[120],"Candida":[123],"albicans.":[124],"Anticancer":[125],"results":[126,218],"modified":[129],"against":[134,165],"various":[135],"kinds":[136],"cancer":[138,161],"cells,":[139,145],"including":[140],"MCF-7,":[141],"Caco-2,":[142],"HepG-2":[144],"indicate":[146],"that":[147],"they":[148],"have":[149],"potent":[151],"effect":[152],"dose-dependent":[155],"manner":[156],"high":[158],"selectivity":[159],"cells":[162,203],"safety":[164],"normal":[166],"cells.":[167,192,215],"expression":[169,194],"levels":[170],"E2F2":[172],"Bcl-2":[174],"genes":[175],"found":[177],"be":[179],"suppressed":[180],"treatment":[182,207],"more":[189,210],"than":[190],"5-FU-treated":[191],"While":[193],"level":[195],"p53":[198,229],"gene":[199,230],"all":[201],"tested":[202,238],"up-regulated":[205],"5\u20138":[208],"folds":[209],"as":[211],"untreated":[214],"docking":[217],"confirmed":[219],"ability":[221],"bind":[226],"relevant":[232],"potency":[233],"binding":[235],"other":[237],"gens":[239],"participation":[241],"cysteine":[243],"SH-functional":[244],"group":[245],"such":[247],"interaction.":[248]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2021-10-11T00:00:00"}