{"id":"https://openalex.org/W3203329338","doi":"https://doi.org/10.1080/2162402x.2021.1974233","title":"Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity?","display_name":"Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity?","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3203329338","doi":"https://doi.org/10.1080/2162402x.2021.1974233","mag":"3203329338","pmid":"https://pubmed.ncbi.nlm.nih.gov/34595058","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8477925"},"language":"en","primary_location":{"id":"doi:10.1080/2162402x.2021.1974233","doi":"https://doi.org/10.1080/2162402x.2021.1974233","is_oa":true,"landing_page_url":"https://doi.org/10.1080/2162402x.2021.1974233","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1974233?needAccess=true","source":{"id":"https://openalex.org/S2497914550","display_name":"OncoImmunology","issn_l":"2162-4011","issn":["2162-4011","2162-402X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315740","host_organization_name":"Landes Bioscience","host_organization_lineage":["https://openalex.org/P4310315740"],"host_organization_lineage_names":["Landes Bioscience"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoImmunology","raw_type":"journal-article"},"volume":null,"type":"editorial","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1974233?needAccess=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028044159","display_name":"Goutham Hassan Venkatesh","orcid":"https://orcid.org/0000-0002-6520-435X","observed_orcids":["https://orcid.org/0000-0002-6520-435X"]},"institutions":[{"id":"https://openalex.org/I163074564","display_name":"Gulf Medical University","ror":"https://ror.org/02kaerj47","country_code":"AE","type":"education","lineage":["https://openalex.org/I163074564"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Goutham Hassan Venkatesh","raw_affiliation_strings":["Gulf Medical University","Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates"],"raw_orcid":"https://orcid.org/0000-0002-6520-435X","affiliations":[{"raw_affiliation_string":"Gulf Medical University","institution_ids":["https://openalex.org/I163074564"]},{"raw_affiliation_string":"Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I163074564"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024325301","display_name":"Raefa Abou Khouzam","orcid":"https://orcid.org/0000-0003-0037-6000","observed_orcids":["https://orcid.org/0000-0003-0037-6000"]},"institutions":[{"id":"https://openalex.org/I163074564","display_name":"Gulf Medical University","ror":"https://ror.org/02kaerj47","country_code":"AE","type":"education","lineage":["https://openalex.org/I163074564"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Raefa Abou Khouzam","raw_affiliation_strings":["Gulf Medical University","Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates"],"raw_orcid":"https://orcid.org/0000-0003-0037-6000","affiliations":[{"raw_affiliation_string":"Gulf Medical University","institution_ids":["https://openalex.org/I163074564"]},{"raw_affiliation_string":"Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I163074564"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090930791","display_name":"Walid El\u2010Sayed","orcid":"https://orcid.org/0000-0002-6647-516X","observed_orcids":["https://orcid.org/0000-0002-6647-516X"]},"institutions":[{"id":"https://openalex.org/I163074564","display_name":"Gulf Medical University","ror":"https://ror.org/02kaerj47","country_code":"AE","type":"education","lineage":["https://openalex.org/I163074564"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Walid Shaaban Moustafa Elsayed","raw_affiliation_strings":["Gulf Medical University","College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates"],"raw_orcid":"https://orcid.org/0000-0002-6647-516X","affiliations":[{"raw_affiliation_string":"Gulf Medical University","institution_ids":["https://openalex.org/I163074564"]},{"raw_affiliation_string":"College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I163074564"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091228071","display_name":"Nagwa Ahmed Zeinelabdin","orcid":"https://orcid.org/0000-0003-2120-737X","observed_orcids":["https://orcid.org/0000-0003-2120-737X"]},"institutions":[{"id":"https://openalex.org/I163074564","display_name":"Gulf Medical University","ror":"https://ror.org/02kaerj47","country_code":"AE","type":"education","lineage":["https://openalex.org/I163074564"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Nagwa Ahmed Zeinelabdin","raw_affiliation_strings":["Gulf Medical University","Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gulf Medical University","institution_ids":["https://openalex.org/I163074564"]},{"raw_affiliation_string":"Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I163074564"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061975059","display_name":"St\u00e9phane Terry","orcid":"https://orcid.org/0000-0003-3089-7886","observed_orcids":["https://orcid.org/0000-0003-3089-7886"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4387152196","display_name":"Immunologie int\u00e9grative des tumeurs et immunoth\u00e9rapie du cancer","ror":"https://ror.org/0266c5p67","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I2801843802","https://openalex.org/I4387152196"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phane Terry","raw_affiliation_strings":["University Paris-Saclay","Inserm Umr 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculty of Medicine, University Paris-Saclay, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Paris-Saclay","institution_ids":["https://openalex.org/I277688954"]},{"raw_affiliation_string":"Inserm Umr 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculty of Medicine, University Paris-Saclay, Villejuif, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4387152196"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045530749","display_name":"Salem Choua\u0131\u0308b","orcid":"https://orcid.org/0009-0007-3228-6882","observed_orcids":["https://orcid.org/0009-0007-3228-6882"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I163074564","display_name":"Gulf Medical University","ror":"https://ror.org/02kaerj47","country_code":"AE","type":"education","lineage":["https://openalex.org/I163074564"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4387152196","display_name":"Immunologie int\u00e9grative des tumeurs et immunoth\u00e9rapie du cancer","ror":"https://ror.org/0266c5p67","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I2801843802","https://openalex.org/I4387152196"]}],"countries":["AE","FR"],"is_corresponding":true,"raw_author_name":"Salem Chouaib","raw_affiliation_strings":["Gulf Medical University","University Paris-Saclay","Inserm Umr 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculty of Medicine, University Paris-Saclay, Villejuif, France","Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gulf Medical University","institution_ids":["https://openalex.org/I163074564"]},{"raw_affiliation_string":"University Paris-Saclay","institution_ids":["https://openalex.org/I277688954"]},{"raw_affiliation_string":"Inserm Umr 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculty of Medicine, University Paris-Saclay, Villejuif, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I277688954","https://openalex.org/I4387152196"]},{"raw_affiliation_string":"Thumbay Research Institute for Precision Medicine, Gulf Medical University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I163074564"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5045530749"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I163074564","https://openalex.org/I277688954","https://openalex.org/I4387152196"],"apc_list":{"value":2375,"currency":"GBP","value_usd":2913},"apc_paid":{"value":2375,"currency":"GBP","value_usd":2913},"fwci":null,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"1","first_page":"1974233","last_page":"1974233"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tumor-hypoxia","display_name":"tumor hypoxia","score":1.0},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.9869999885559082},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.8619999885559082},{"id":"https://openalex.org/keywords/tumor-immunogenicity","display_name":"tumor immunogenicity","score":0.8820000290870667},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.8920000195503235},{"id":"https://openalex.org/keywords/tumor-immunology","display_name":"tumor immunology","score":0.6880000233650208}],"concepts":[{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.7531028985977173},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.7500998973846436},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.6725642085075378},{"id":"https://openalex.org/C2779081379","wikidata":"https://www.wikidata.org/wiki/Q7852677","display_name":"Tumor hypoxia","level":3,"score":0.5969595909118652},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5560219883918762},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48860031366348267},{"id":"https://openalex.org/C2779256057","wikidata":"https://www.wikidata.org/wiki/Q16909647","display_name":"Tumor progression","level":3,"score":0.424843966960907},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3098447918891907},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.30206409096717834},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2847902476787567},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2488822042942047},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.24640706181526184},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2293790876865387},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.12155666947364807},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08028307557106018},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072258","descriptor_name":"Tumor Hypoxia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009385","descriptor_name":"Neoplastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1080/2162402x.2021.1974233","doi":"https://doi.org/10.1080/2162402x.2021.1974233","is_oa":true,"landing_page_url":"https://doi.org/10.1080/2162402x.2021.1974233","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1974233?needAccess=true","source":{"id":"https://openalex.org/S2497914550","display_name":"OncoImmunology","issn_l":"2162-4011","issn":["2162-4011","2162-402X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315740","host_organization_name":"Landes Bioscience","host_organization_lineage":["https://openalex.org/P4310315740"],"host_organization_lineage_names":["Landes Bioscience"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoImmunology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:7368165","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8477925","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:8477925","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8477925","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncoimmunology","raw_type":"Text"},{"id":"pmid:34595058","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34595058","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncoimmunology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:6105cf679eab46ee9fc449594f21378f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6105cf679eab46ee9fc449594f21378f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"OncoImmunology, Vol 10, Iss 1 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1080/2162402x.2021.1974233","doi":"https://doi.org/10.1080/2162402x.2021.1974233","is_oa":true,"landing_page_url":"https://doi.org/10.1080/2162402x.2021.1974233","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1974233?needAccess=true","source":{"id":"https://openalex.org/S2497914550","display_name":"OncoImmunology","issn_l":"2162-4011","issn":["2162-4011","2162-402X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315740","host_organization_name":"Landes Bioscience","host_organization_lineage":["https://openalex.org/P4310315740"],"host_organization_lineage_names":["Landes Bioscience"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoImmunology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3953594154","display_name":null,"funder_award_id":"MRG-230/20172018 and MRG-266/20172018","funder_id":"https://openalex.org/F4320313185","funder_display_name":"Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320313185","display_name":"Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences","ror":null}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3203329338.pdf"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W2051818303","https://openalex.org/W2089623593","https://openalex.org/W2092715192","https://openalex.org/W2109424201","https://openalex.org/W2113836212","https://openalex.org/W2149360266","https://openalex.org/W2256481109","https://openalex.org/W2463432841","https://openalex.org/W2524686241","https://openalex.org/W2638401050","https://openalex.org/W2768178292","https://openalex.org/W2769873734","https://openalex.org/W2789389364","https://openalex.org/W2890762462","https://openalex.org/W2901068426","https://openalex.org/W2908755714","https://openalex.org/W2942594871","https://openalex.org/W2968129041","https://openalex.org/W2973106902","https://openalex.org/W2999574447","https://openalex.org/W3004442100","https://openalex.org/W3016857799","https://openalex.org/W3033093898","https://openalex.org/W3039259060","https://openalex.org/W3044623646","https://openalex.org/W3067067067","https://openalex.org/W3076622137","https://openalex.org/W3083391098","https://openalex.org/W3084020520","https://openalex.org/W3084896449","https://openalex.org/W3096394571","https://openalex.org/W3104391539","https://openalex.org/W3105191616","https://openalex.org/W3110302947","https://openalex.org/W3112974929","https://openalex.org/W3113881752","https://openalex.org/W3118395892","https://openalex.org/W3118722733","https://openalex.org/W3118727674","https://openalex.org/W3121605775","https://openalex.org/W3122483411","https://openalex.org/W3123768250","https://openalex.org/W3127698625","https://openalex.org/W3128836376","https://openalex.org/W3129028529","https://openalex.org/W3129927254","https://openalex.org/W3132791675","https://openalex.org/W3134978829","https://openalex.org/W3137642284","https://openalex.org/W3137777587","https://openalex.org/W3139143383","https://openalex.org/W3142377309","https://openalex.org/W3153155506","https://openalex.org/W3161232073","https://openalex.org/W3162668660","https://openalex.org/W3173975756","https://openalex.org/W3176619285","https://openalex.org/W4213088995"],"related_works":["https://openalex.org/W3187751359","https://openalex.org/W4404698311","https://openalex.org/W4282013377","https://openalex.org/W4388312659","https://openalex.org/W149336259","https://openalex.org/W7072227593","https://openalex.org/W3041568835","https://openalex.org/W2323751645","https://openalex.org/W2173177095","https://openalex.org/W2921330079"],"abstract_inverted_index":{"Hypoxia":[0],"in":[1],"the":[2],"tumor":[3,14,26],"microenvironment":[4],"has":[5],"been":[6],"shown":[7],"to":[8],"be":[9],"a":[10],"strong":[11],"indicator":[12],"of":[13],"aggressiveness,":[15],"metastases,":[16],"and":[17],"promotes":[18],"cancer":[19],"progression.1":[20],"Several":[21],"studies":[22],"have":[23],"indicated":[24],"that":[25],"hypoxi...":[27]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-10-11T00:00:00"}