{"id":"https://openalex.org/W3203299178","doi":null,"title":"Phenytoin toxicity presenting with acute visual loss and acute delirium, a case report","display_name":"Phenytoin toxicity presenting with acute visual loss and acute delirium, a case report","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W3203299178","mag":"3203299178"},"language":"en","primary_location":{"id":"pmh:oai:eprints.um.edu.my:22226","doi":null,"is_oa":true,"landing_page_url":"http://eprints.um.edu.my/22226/","pdf_url":"https://www.neurology-asia.org/articles/neuroasia-2018-23(4)-363.pdf","source":{"id":"https://openalex.org/S4306400330","display_name":"The University of Malaya Research Repository (University of Malaya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I33849332","host_organization_name":"University of Malaya","host_organization_lineage":["https://openalex.org/I33849332"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.neurology-asia.org/articles/neuroasia-2018-23(4)-363.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028821851","display_name":"Sin Hong Chew","orcid":"https://orcid.org/0000-0002-4697-5415","observed_orcids":["https://orcid.org/0000-0002-4697-5415"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sin Hong Chew","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4697-5415","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078843931","display_name":"Irene Looi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Irene Looi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015575968","display_name":"Yoke Lin Lo","orcid":"https://orcid.org/0000-0001-5521-2543","observed_orcids":["https://orcid.org/0000-0001-5521-2543"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoke\u2010Lin Lo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5521-2543","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5011309022","display_name":"Kheng Seang Lim","orcid":"https://orcid.org/0000-0002-2787-2365","observed_orcids":["https://orcid.org/0000-0002-2787-2365"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kheng Seang Lim","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2787-2365","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1641,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.4787907,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.8169000148773193,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.8169000148773193,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.06949999928474426,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13467","display_name":"Drug-Induced Ocular Toxicity","score":0.05480000004172325,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phenytoin-toxicity","display_name":"phenytoin toxicity","score":0.9909999966621399},{"id":"https://openalex.org/keywords/acute-delirium","display_name":"acute delirium","score":0.8679999709129333},{"id":"https://openalex.org/keywords/focal-epilepsy","display_name":"focal epilepsy","score":0.9259999990463257},{"id":"https://openalex.org/keywords/antiepileptic-drug-side-effects","display_name":"antiepileptic drug adverse effects","score":0.8619999885559082},{"id":"https://openalex.org/keywords/serum-phenytoin-concentration","display_name":"serum phenytoin concentration","score":0.8460000157356262},{"id":"https://openalex.org/keywords/medication-discontinuation","display_name":"drug discontinuation","score":0.6679999828338623}],"concepts":[{"id":"https://openalex.org/C2778337148","wikidata":"https://www.wikidata.org/wiki/Q410400","display_name":"Phenytoin","level":3,"score":0.9479703903198242},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7346230745315552},{"id":"https://openalex.org/C2779753318","wikidata":"https://www.wikidata.org/wiki/Q160796","display_name":"Delirium","level":2,"score":0.704022228717804},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.6765316128730774},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6048856377601624},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.5610271692276001},{"id":"https://openalex.org/C2781372952","wikidata":"https://www.wikidata.org/wiki/Q737460","display_name":"Visual impairment","level":2,"score":0.416779488325119},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.2518363296985626},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15180012583732605},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:eprints.um.edu.my:22226","doi":null,"is_oa":true,"landing_page_url":"http://eprints.um.edu.my/22226/","pdf_url":"https://www.neurology-asia.org/articles/neuroasia-2018-23(4)-363.pdf","source":{"id":"https://openalex.org/S4306400330","display_name":"The University of Malaya Research Repository (University of Malaya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I33849332","host_organization_name":"University of Malaya","host_organization_lineage":["https://openalex.org/I33849332"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"mag:3203299178","doi":null,"is_oa":false,"landing_page_url":"http://eprints.um.edu.my/22226/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:eprints.um.edu.my:22226","doi":null,"is_oa":true,"landing_page_url":"http://eprints.um.edu.my/22226/","pdf_url":"https://www.neurology-asia.org/articles/neuroasia-2018-23(4)-363.pdf","source":{"id":"https://openalex.org/S4306400330","display_name":"The University of Malaya Research Repository (University of Malaya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I33849332","host_organization_name":"University of Malaya","host_organization_lineage":["https://openalex.org/I33849332"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3203299178.pdf","grobid_xml":"https://content.openalex.org/works/W3203299178.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W23440909","https://openalex.org/W1981057943","https://openalex.org/W4396219855","https://openalex.org/W7116631346","https://openalex.org/W2916642204","https://openalex.org/W2015505795","https://openalex.org/W2963491262","https://openalex.org/W7096034780","https://openalex.org/W20234054","https://openalex.org/W4380667558"],"abstract_inverted_index":{"Phenytoin":[0],"is":[1],"a":[2,15,18],"widely":[3],"prescribed":[4],"antiepileptic":[5],"agent":[6],"for":[7,69],"both":[8],"focal":[9,22],"and":[10,30],"generalized":[11],"seizure.":[12],"We":[13],"report":[14],"case":[16,73],"of":[17,48],"20-year-old":[19],"man":[20],"with":[21,25],"epilepsy":[23],"presented":[24],"acute":[26,76],"bilateral":[27],"visual":[28,62,83],"loss,":[29],"delirium.":[31],"His":[32,61],"random":[33],"phenytoin":[34,68,77],"serum":[35],"concentration":[36],"on":[37],"admission":[38],"was":[39],"43.6":[40],"mg/L,":[41],"well":[42],"above":[43],"the":[44],"recommended":[45],"therapeutic":[46],"range":[47],"10-20":[49],"mg/L.":[50],"Extensive":[51],"investigations":[52],"have":[53],"ruled":[54],"out":[55],"other":[56],"vascular":[57],"or":[58],"demyelinating":[59],"causes.":[60],"symptoms":[63],"completely":[64],"resolved":[65],"after":[66],"discontinuing":[67],"84":[70],"hours.":[71],"This":[72],"shows":[74],"that":[75],"toxicity":[78],"can":[79],"result":[80],"in":[81],"reversible":[82],"failure.":[84]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2021-10-11T00:00:00"}