{"id":"https://openalex.org/W3203078429","doi":"https://doi.org/10.1038/s41598-021-98233-z","title":"Strain maps characterize the symmetry of convergence and extension patterns during zebrafish gastrulation","display_name":"Strain maps characterize the symmetry of convergence and extension patterns during zebrafish gastrulation","publication_year":2021,"publication_date":"2021-09-29","ids":{"openalex":"https://openalex.org/W3203078429","doi":"https://doi.org/10.1038/s41598-021-98233-z","mag":"3203078429","pmid":"https://pubmed.ncbi.nlm.nih.gov/34588480","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8481280"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-021-98233-z","doi":"https://doi.org/10.1038/s41598-021-98233-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-021-98233-z","pdf_url":"https://www.nature.com/articles/s41598-021-98233-z.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-021-98233-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028833612","display_name":"Dipanjan Bhattacharya","orcid":"https://orcid.org/0000-0002-6409-4291","observed_orcids":["https://orcid.org/0000-0002-6409-4291"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210114103","display_name":"IFOM","ror":"https://ror.org/02hcsa680","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210114103"]},{"id":"https://openalex.org/I4405277086","display_name":"Mechanobiology Institute","ror":"https://ror.org/01dh8a666","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4405277086"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["IT","SG","US"],"is_corresponding":true,"raw_author_name":"Dipanjan Bhattacharya","raw_affiliation_strings":["Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore. dipanjan.bhattacharya@ifom.eu","Institute FIRC of Molecular Oncology (IFOM), 20139, Milan, Italy. dipanjan.bhattacharya@ifom.eu","MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore. dipanjan.bhattacharya@ifom.eu","Singapore-Massachusetts Institute of Technology Alliance of Research and Technology (SMART), National University of Singapore, Singapore, 117548, Singapore. dipanjan.bhattacharya@ifom.eu","Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore. dipanjan.bhattacharya@ifom.eu","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Institute FIRC of Molecular Oncology (IFOM), 20139, Milan, Italy. dipanjan.bhattacharya@ifom.eu","institution_ids":["https://openalex.org/I4210114103"]},{"raw_affiliation_string":"MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore. dipanjan.bhattacharya@ifom.eu","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4405277086"]},{"raw_affiliation_string":"Singapore-Massachusetts Institute of Technology Alliance of Research and Technology (SMART), National University of Singapore, Singapore, 117548, Singapore. dipanjan.bhattacharya@ifom.eu","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4405277086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001836457","display_name":"Jun Zhong","orcid":"https://orcid.org/0000-0003-0155-6804","observed_orcids":["https://orcid.org/0000-0003-0155-6804"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4405277086","display_name":"Mechanobiology Institute","ror":"https://ror.org/01dh8a666","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4405277086"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jun Zhong","raw_affiliation_strings":["Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4405277086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103238225","display_name":"Sahar Tavakoli","orcid":"https://orcid.org/0000-0003-3413-1554","observed_orcids":["https://orcid.org/0000-0003-3413-1554"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210157861","display_name":"Harvard Stem Cell Institute","ror":"https://ror.org/04kj1hn59","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}],"countries":["SG","US"],"is_corresponding":false,"raw_author_name":"Sahar Tavakoli","raw_affiliation_strings":["Boston Children's Hospital, Boston, 02115, USA","Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, 02138, USA","Harvard Stem Cell Institute, Harvard University, Cambridge, 02138, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston Children's Hospital, Boston, 02115, USA","institution_ids":["https://openalex.org/I1288882113"]},{"raw_affiliation_string":"Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, 02138, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard Stem Cell Institute, Harvard University, Cambridge, 02138, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210157861"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074932834","display_name":"Alexandre Kabla","orcid":"https://orcid.org/0000-0002-0280-3531","observed_orcids":["https://orcid.org/0000-0002-0280-3531"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexandre Kabla","raw_affiliation_strings":["Department of Engineering, University of Cambridge, Cambridge, CB2 1PZ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Engineering, University of Cambridge, Cambridge, CB2 1PZ, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084983005","display_name":"Paul Thomas Matsudaira","orcid":"https://orcid.org/0000-0002-8399-3276","observed_orcids":["https://orcid.org/0000-0002-8399-3276"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4405277086","display_name":"Mechanobiology Institute","ror":"https://ror.org/01dh8a666","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4405277086"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["SG","US"],"is_corresponding":false,"raw_author_name":"Paul Matsudaira","raw_affiliation_strings":["Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore","Singapore-Massachusetts Institute of Technology Alliance of Research and Technology (SMART), National University of Singapore, Singapore, 117548, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for BioImaging Sciences (CBIS), Department of Biological Sciences, National University of Singapore, Singapore, 117543, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"MechanoBiology Institute, National University of Singapore, Singapore, 117411, Singapore","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4405277086"]},{"raw_affiliation_string":"Singapore-Massachusetts Institute of Technology Alliance of Research and Technology (SMART), National University of Singapore, Singapore, 117548, Singapore","institution_ids":["https://openalex.org/I165932596","https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5028833612"],"corresponding_institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4210114103","https://openalex.org/I4405277086","https://openalex.org/I63966007"],"apc_list":{"value":1990,"currency":"USD","value_usd":1990},"apc_paid":{"value":1990,"currency":"USD","value_usd":1990},"fwci":0.6287,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.59380697,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"11","issue":"1","first_page":"19357","last_page":"19357"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.5776000022888184,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.5776000022888184,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.24940000474452972,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.1339000016450882,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zebrafish-gastrulation","display_name":"zebrafish gastrulation","score":0.9449999928474426},{"id":"https://openalex.org/keywords/tissue-mechanics","display_name":"tissue mechanics","score":0.5860000252723694},{"id":"https://openalex.org/keywords/epiboly","display_name":"epiboly","score":0.8500000238418579},{"id":"https://openalex.org/keywords/left-right-symmetry","display_name":"left-right symmetry","score":0.6349999904632568},{"id":"https://openalex.org/keywords/anteroposterior-axis","display_name":"anterior-posterior axis","score":0.6990000009536743},{"id":"https://openalex.org/keywords/dorsoventral-axis","display_name":"dorsal-ventral axis","score":0.9350000023841858},{"id":"https://openalex.org/keywords/tectonics","display_name":"tectonics","score":0.7279999852180481},{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.597000002861023},{"id":"https://openalex.org/keywords/embryonic-segmentation","display_name":"embryonic segmentation","score":0.44699999690055847},{"id":"https://openalex.org/keywords/neurulation","display_name":"neurulation","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C129536746","wikidata":"https://www.wikidata.org/wiki/Q1141026","display_name":"Gastrulation","level":4,"score":0.8792139291763306},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.6513468027114868},{"id":"https://openalex.org/C98535976","wikidata":"https://www.wikidata.org/wiki/Q4088022","display_name":"Blastoderm","level":4,"score":0.6466164588928223},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49786829948425293},{"id":"https://openalex.org/C192586883","wikidata":"https://www.wikidata.org/wiki/Q5166400","display_name":"Convergent extension","level":5,"score":0.48559993505477905},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.45202162861824036},{"id":"https://openalex.org/C92375311","wikidata":"https://www.wikidata.org/wiki/Q1484637","display_name":"Epiboly","level":5,"score":0.4369655251502991},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.43621882796287537},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.2899150550365448},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2637425363063812},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1554654836654663}],"mesh":[{"descriptor_ui":"D000069416","descriptor_name":"Intravital Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D011725","descriptor_name":"Pyridines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019521","descriptor_name":"Body Patterning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019521","descriptor_name":"Body Patterning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D029961","descriptor_name":"Zebrafish Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D029961","descriptor_name":"Zebrafish Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044482","descriptor_name":"Benzeneacetamides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051153","descriptor_name":"Wnt Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051153","descriptor_name":"Wnt Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054262","descriptor_name":"Gastrulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D054262","descriptor_name":"Gastrulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":11,"locations":[{"id":"doi:10.1038/s41598-021-98233-z","doi":"https://doi.org/10.1038/s41598-021-98233-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-021-98233-z","pdf_url":"https://www.nature.com/articles/s41598-021-98233-z.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"doi:10.1101/407940","doi":"https://doi.org/10.1101/407940","is_oa":true,"landing_page_url":"https://doi.org/10.1101/407940","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2018/09/04/407940.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:7375857","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC8481280","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:34588480","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34588480","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8481280","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8481280/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/233028","doi":null,"is_oa":true,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/233028","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus OA2021","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:78d28d1de5274be8a614a4b4705eb4b1","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/78d28d1de5274be8a614a4b4705eb4b1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)","raw_type":"article"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/328806","doi":null,"is_oa":true,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/328806","pdf_url":null,"source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/328977","doi":null,"is_oa":true,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/328977","pdf_url":null,"source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"doi:10.17863/cam.76253","doi":"https://doi.org/10.17863/cam.76253","is_oa":true,"landing_page_url":"https://doi.org/10.17863/cam.76253","pdf_url":null,"source":{"id":"https://openalex.org/S7407050737","display_name":"Apollo","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.17863/cam.76421","doi":"https://doi.org/10.17863/cam.76421","is_oa":true,"landing_page_url":"https://doi.org/10.17863/cam.76421","pdf_url":null,"source":{"id":"https://openalex.org/S7407050737","display_name":"Apollo","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1038/s41598-021-98233-z","doi":"https://doi.org/10.1038/s41598-021-98233-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-021-98233-z","pdf_url":"https://www.nature.com/articles/s41598-021-98233-z.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2059922122","display_name":"Quantifying cell behaviour in morphogenesis","funder_award_id":"EP/F058586/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6056808448","display_name":"Micromechanical measurements in living embryos","funder_award_id":"BB/K018175/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8435977132","display_name":null,"funder_award_id":"BB/K018175","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320320698","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49"},{"id":"https://openalex.org/F4320322724","display_name":"Ministry of Education, India","ror":"https://ror.org/048xjjh50"},{"id":"https://openalex.org/F4320324605","display_name":"Mechanobiology Institute, Singapore","ror":"https://ror.org/01tgyzw49"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3203078429.pdf","grobid_xml":"https://content.openalex.org/works/W3203078429.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1523269786","https://openalex.org/W1871515736","https://openalex.org/W1970083872","https://openalex.org/W1971831631","https://openalex.org/W1974660048","https://openalex.org/W1974712344","https://openalex.org/W1980059877","https://openalex.org/W1981044612","https://openalex.org/W1985817016","https://openalex.org/W1986158200","https://openalex.org/W1992172233","https://openalex.org/W2007817359","https://openalex.org/W2008079477","https://openalex.org/W2021328573","https://openalex.org/W2031312855","https://openalex.org/W2042771899","https://openalex.org/W2075359789","https://openalex.org/W2083571731","https://openalex.org/W2091119718","https://openalex.org/W2098410928","https://openalex.org/W2101336732","https://openalex.org/W2116959561","https://openalex.org/W2125349610","https://openalex.org/W2145013849","https://openalex.org/W2164637607","https://openalex.org/W2167352593","https://openalex.org/W2183128937","https://openalex.org/W2210388544","https://openalex.org/W2522174175","https://openalex.org/W2602818789","https://openalex.org/W2901083302","https://openalex.org/W7049080086"],"related_works":["https://openalex.org/W2584092274","https://openalex.org/W4403271887","https://openalex.org/W2623434667","https://openalex.org/W3165259784","https://openalex.org/W4214627632","https://openalex.org/W2623609984","https://openalex.org/W2400515097","https://openalex.org/W7154916010","https://openalex.org/W7213452188","https://openalex.org/W2995034929"],"abstract_inverted_index":{"Abstract":[0],"During":[1,111],"gastrulation":[2,154],"of":[3,9,18,36,66,82,95,108,149,165,173,182,201,230,243],"the":[4,7,14,19,34,64,80,83,93,104,109,118,131,138,144,163,171,188,195,199,217,227,235],"zebrafish":[5],"embryo,":[6],"cap":[8],"blastoderm":[10],"cells":[11],"organizes":[12],"into":[13,85],"axial":[15,119,218],"body":[16],"plan":[17],"embryo":[20,84,236],"with":[21,206],"left\u2013right":[22],"symmetry":[23],"and":[24,39,98,114,120,127,134,141,151,167,193,214,220,245],"head\u2013tail,":[25],"dorsal\u2013ventral":[26,139],"polarities.":[27],"Our":[28],"labs":[29],"have":[30,40],"been":[31],"interested":[32],"in":[33,106,117,187],"mechanics":[35],"early":[37,72],"development":[38],"investigated":[41],"whether":[42],"these":[43,96],"large-scale":[44,231],"cell":[45],"movements":[46,94,148],"can":[47,237],"be":[48,238],"described":[49],"as":[50,125],"tissue-level":[51],"mechanical":[52],"strain":[53,100,155],"by":[54,74,158,198],"a":[55,208,241],"tectonics-based":[56],"approach.":[57],"The":[58],"first":[59,185],"step":[60],"is":[61,156],"to":[62,71,143,177,240],"image":[63],"positions":[65],"all":[67],"nuclei":[68],"from":[69,92,103],"mid-epiboly":[70,192],"segmentation":[73,166],"digital":[75],"sheet":[76],"light":[77],"microscopy,":[78],"organize":[79],"surface":[81],"multi-cell":[86],"spherical":[87],"domains,":[88],"construct":[89],"velocity":[90],"fields":[91],"domains":[97],"extract":[99],"rate":[101],"maps":[102],"change":[105],"density":[107],"domains.":[110],"gastrulation,":[112],"tensile/expansive":[113],"compressive":[115],"strains":[116],"equatorial":[121],"directions":[122],"are":[123,184,223],"detected":[124,186],"anterior":[126,168],"posterior":[128],"expansion":[129,161,169],"along":[130],"anterior\u2013posterior":[132],"axis":[133,140],"medial\u2013lateral":[135],"compression":[136],"across":[137,234],"corresponds":[142],"well":[145],"characterized":[146],"morphological":[147],"convergence":[150],"extension.":[152],"Following":[153],"represented":[157],"localized":[159],"medial":[160],"at":[162,170,191],"onset":[164,172],"neurulation.":[174],"In":[175,203],"addition":[176],"linear":[178],"strain,":[179],"symmetric":[180],"patterns":[181],"rotation/curl":[183],"animal":[189],"hemispheres":[190,197],"then":[194],"vegetal":[196,221],"end":[200],"gastrulation.":[202],"embryos":[204],"treated":[205],"C59,":[207],"Wnt":[209],"inhibitor":[210],"that":[211],"inhibits":[212],"head":[213],"tail":[215],"extension,":[216],"extension":[219],"curl":[222],"absent.":[224],"By":[225],"analysing":[226],"temporal":[228],"sequence":[229],"movements,":[232],"deformations":[233],"attributed":[239],"combination":[242],"epiboly":[244],"dorsal":[246],"convergence-extension.":[247]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-10-11T00:00:00"}
