{"id":"https://openalex.org/W3203061567","doi":"https://doi.org/10.25789/ymj.2021.75.22","title":"Cellular and molecular mechanisms of action of neurosteroids in various parts of the central nervous system (Part 2)","display_name":"Cellular and molecular mechanisms of action of neurosteroids in various parts of the central nervous system (Part 2)","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3203061567","doi":"https://doi.org/10.25789/ymj.2021.75.22","mag":"3203061567"},"language":"en","primary_location":{"id":"doi:10.25789/ymj.2021.75.22","doi":"https://doi.org/10.25789/ymj.2021.75.22","is_oa":true,"landing_page_url":"https://doi.org/10.25789/ymj.2021.75.22","pdf_url":null,"source":{"id":"https://openalex.org/S4210193651","display_name":"Yakut Medical Journal","issn_l":"1813-1905","issn":["1813-1905","2312-1017"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yakut Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.25789/ymj.2021.75.22","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037778467","display_name":"\u0414. \u0412. \u0414\u043c\u0438\u0442\u0440\u0435\u043d\u043a\u043e","orcid":"https://orcid.org/0000-0003-4639-6365","observed_orcids":["https://orcid.org/0000-0003-4639-6365"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D.V. Dmitrenko","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4639-6365","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044795716","display_name":"\u0417\u043e\u0431\u043e\u0432\u0430 \u0421\u0432\u0435\u0442\u043b\u0430\u043d\u0430 \u041d\u0438\u043a\u043e\u043b\u0430\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0003-2748-3164","observed_orcids":["https://orcid.org/0000-0003-2748-3164"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S.N. Zobova","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2748-3164","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074974043","display_name":"Tatiana Gennadievna Ruksha","orcid":"https://orcid.org/0000-0001-8142-4283","observed_orcids":["https://orcid.org/0000-0001-8142-4283"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T.G. Ruksha","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8142-4283","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035713453","display_name":"\u0422. I. Prusova","orcid":"https://orcid.org/0000-0001-8844-0622","observed_orcids":["https://orcid.org/0000-0001-8844-0622"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T.I. Prusova","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8844-0622","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065610255","display_name":"\u0423\u0441\u043e\u043b\u044c\u0446\u0435\u0432\u0430 \u0410\u043d\u043d\u0430 \u0410\u043b\u0435\u043a\u0441\u0430\u043d\u0434\u0440\u043e\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0002-9678-6719","observed_orcids":["https://orcid.org/0000-0002-9678-6719"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A.A. Usoltseva","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9678-6719","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"3","first_page":"85","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurosteroids","display_name":"neurosteroids","score":0.996999979019165},{"id":"https://openalex.org/keywords/progesterone","display_name":"progesterone","score":0.9010000228881836},{"id":"https://openalex.org/keywords/allopregnanolone","display_name":"allopregnanolone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dehydroepiandrosterone","display_name":"dehydroepiandrosterone","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dehydroepiandrosterone-sulfate","display_name":"dehydroepiandrosterone sulfate","score":0.972000002861023},{"id":"https://openalex.org/keywords/neurosteroid-synthesis","display_name":"neurosteroid synthesis","score":0.7940000295639038},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.7960000038146973},{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"central nervous system","score":0.7239999771118164},{"id":"https://openalex.org/keywords/steroid-hormone-receptors","display_name":"steroid hormone receptors","score":0.574999988079071}],"concepts":[{"id":"https://openalex.org/C44796713","wikidata":"https://www.wikidata.org/wiki/Q2659374","display_name":"Neuroactive steroid","level":4,"score":0.9237381219863892},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.752352237701416},{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.7480469942092896},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.5771967768669128},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.43646439909935},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.35411280393600464},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.299628883600235},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.24355021119117737},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11005324125289917},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07775384187698364},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06450453400611877},{"id":"https://openalex.org/C168258287","wikidata":"https://www.wikidata.org/wiki/Q60147","display_name":"GABAA receptor","level":3,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.25789/ymj.2021.75.22","doi":"https://doi.org/10.25789/ymj.2021.75.22","is_oa":true,"landing_page_url":"https://doi.org/10.25789/ymj.2021.75.22","pdf_url":null,"source":{"id":"https://openalex.org/S4210193651","display_name":"Yakut Medical Journal","issn_l":"1813-1905","issn":["1813-1905","2312-1017"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yakut Medical Journal","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:c1b7f593d615428cb11b965ac3fe7762","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/c1b7f593d615428cb11b965ac3fe7762","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u042f\u043a\u0443\u0442\u0441\u043a\u0438\u0439 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0439 \u0436\u0443\u0440\u043d\u0430\u043b, Vol 0, Iss 3, Pp 85-91 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.25789/ymj.2021.75.22","doi":"https://doi.org/10.25789/ymj.2021.75.22","is_oa":true,"landing_page_url":"https://doi.org/10.25789/ymj.2021.75.22","pdf_url":null,"source":{"id":"https://openalex.org/S4210193651","display_name":"Yakut Medical Journal","issn_l":"1813-1905","issn":["1813-1905","2312-1017"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yakut Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2052504532","https://openalex.org/W3176440281","https://openalex.org/W3027628483","https://openalex.org/W4288033708","https://openalex.org/W2394995650","https://openalex.org/W2391301509","https://openalex.org/W2039299884","https://openalex.org/W2351807769","https://openalex.org/W2048463939","https://openalex.org/W7058499910"],"abstract_inverted_index":{"Neurosteroids":[0],"(or":[1],"neuroactive":[2],"steroids)":[3],"are":[4,11,34],"a":[5],"class":[6,25],"of":[7,36,51,60,63],"endogenous":[8],"compounds":[9],"which":[10,33],"synthesized":[12,78],"in":[13],"nervous":[14],"tissue":[15],"or\\and":[16],"able":[17],"to":[18,43],"modulate":[19],"the":[20,24,39,52],"brain":[21,41],"functional":[22],"activity,":[23],"also":[26],"includes":[27],"steroids":[28],"from":[29],"gonads":[30],"or":[31],"adrenals,":[32],"capable":[35],"migrating":[37],"through":[38],"blood":[40],"barrier":[42],"achieve":[44],"their":[45,76],"biological":[46],"targets.":[47],"The":[48],"second":[49],"part":[50],"review":[53],"is":[54],"focused":[55],"on":[56],"describing":[57],"multiply":[58],"features":[59],"synthesis,":[61],"functioning":[62],"such":[64],"neurosteroids":[65],"as":[66,73,75],"progesterone,":[67],"allopregnanolone,":[68],"dehydroepiandrosterone":[69,71],"and":[70],"sulfate":[72],"well":[74],"targets,":[77],"analogs.":[79]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2021-10-11T00:00:00"}