{"id":"https://openalex.org/W3202979080","doi":null,"title":"Isolation of Nontoxic Fraction from Swietenia Mahagoni Seed and its Hypoglycemic Activity in Normal and Diabetic Rats","display_name":"Isolation of Nontoxic Fraction from Swietenia Mahagoni Seed and its Hypoglycemic Activity in Normal and Diabetic Rats","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W3202979080","mag":"3202979080"},"language":"en","primary_location":{"id":"mag:3202979080","doi":null,"is_oa":false,"landing_page_url":"https://www.jocpr.com/articles/isolation-of-nontoxic-fraction-from-swietenia-mahagoni-seed-and-its-hypoglycemic-activity-in-normal-and-diabetic-rats.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764823877","display_name":"Journal of chemical and pharmaceutical research","issn_l":"0975-7384","issn":["0975-7384"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4328139297","host_organization_name":"JOCPR","host_organization_lineage":["https://openalex.org/P4328139297"],"host_organization_lineage_names":["JOCPR"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of chemical and pharmaceutical research","raw_type":null},"parent_works":[],"lineage":["https://openalex.org/W3202979080"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016373351","display_name":"Jannatul Naima","orcid":"https://orcid.org/0009-0002-7718-7128","observed_orcids":["https://orcid.org/0009-0002-7718-7128","https://orcid.org/0000-0001-6005-4455"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jannatul Naima","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6005-4455","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039585808","display_name":"Nawreen Monir Proma","orcid":"https://orcid.org/0000-0002-5877-8638","observed_orcids":["https://orcid.org/0000-0002-5877-8638"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nawreen Monir Proma","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5877-8638","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101548204","display_name":"Mohammad Rashedul Islam","orcid":"https://orcid.org/0000-0002-7632-5157","observed_orcids":["https://orcid.org/0000-0002-7632-5157"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammad Rashedul Islam","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7632-5157","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051775926","display_name":"Jahirul Alam Papel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jahirul Alam Papel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083904602","display_name":"Mohammed Monzur Rahman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammed Monzur Rahman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5018851554","display_name":"Mohammed Kamrul Hossain","orcid":"https://orcid.org/0000-0003-3462-1086","observed_orcids":["https://orcid.org/0000-0003-3462-1086"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammed Kamrul Hossain","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3462-1086","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1938,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.52594825,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"9","issue":"10","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/swietenia-mahagoni","display_name":"Swietenia mahagoni","score":0.9990000128746033},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.8289999961853027},{"id":"https://openalex.org/keywords/hypoglycemic-activity","display_name":"hypoglycemic activity","score":0.9139999747276306},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9430000185966492},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9599999785423279},{"id":"https://openalex.org/keywords/plasma-glucose","display_name":"plasma glucose","score":0.8880000114440918},{"id":"https://openalex.org/keywords/plasma-insulin","display_name":"plasma insulin","score":0.8069999814033508},{"id":"https://openalex.org/keywords/insulin-sensitization","display_name":"insulin sensitization","score":0.6959999799728394},{"id":"https://openalex.org/keywords/serum-lipids","display_name":"serum lipids","score":0.4230000078678131},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.40799999237060547}],"concepts":[{"id":"https://openalex.org/C2779768347","wikidata":"https://www.wikidata.org/wiki/Q420626","display_name":"Glibenclamide","level":3,"score":0.8701522350311279},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5490635633468628},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5441665649414062},{"id":"https://openalex.org/C2991699492","wikidata":"https://www.wikidata.org/wiki/Q12955947","display_name":"Swietenia macrophylla","level":2,"score":0.5409229397773743},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4905371069908142},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4462069571018219},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.3962864875793457},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39497578144073486},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32782378792762756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21293509006500244},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.19872424006462097}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3202979080","doi":null,"is_oa":false,"landing_page_url":"https://www.jocpr.com/articles/isolation-of-nontoxic-fraction-from-swietenia-mahagoni-seed-and-its-hypoglycemic-activity-in-normal-and-diabetic-rats.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764823877","display_name":"Journal of chemical and pharmaceutical research","issn_l":"0975-7384","issn":["0975-7384"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4328139297","host_organization_name":"JOCPR","host_organization_lineage":["https://openalex.org/P4328139297"],"host_organization_lineage_names":["JOCPR"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of chemical and pharmaceutical research","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2257955006","https://openalex.org/W1987755488","https://openalex.org/W2526596544","https://openalex.org/W2261087569","https://openalex.org/W2029410768","https://openalex.org/W2008227760","https://openalex.org/W2014781859","https://openalex.org/W4297786588","https://openalex.org/W2910495874"],"abstract_inverted_index":{"Swietenia":[0,49,89,199],"mahagoni":[1,90,200],"is":[2],"a":[3,58,77,97],"tropical":[4],"ever-green":[5],"hardwood":[6],"timber":[7],"species":[8],"of":[9,17,28,32,41,44,61,64,88,198],"Meliaceace":[10],"family.":[11],"In":[12],"recent":[13],"years":[14],"increasing":[15],"number":[16],"Bangladeshi":[18],"people":[19],"are":[20],"using":[21],"the":[22,26,33,38,47,118,157],"Mahagoni":[23],"seeds":[24,45],"for":[25,91],"management":[27],"diabetes.":[29],"The":[30,81,191],"aim":[31],"investigation":[34],"was":[35,55,74,125,153,175],"to":[36,213],"evaluate":[37],"antidiabetic":[39,79,203],"activity":[40,132],"Sm-SEF7":[42,158,196],"fraction":[43,184,197],"from":[46],"plant":[48],"mahagoniinstreptozocin":[50],"induced":[51,56],"diabetic":[52,95,208],"rats.":[53,70,190,210],"Diabetes":[54],"by":[57],"single":[59],"dose":[60],"intraperitoneal":[62],"injection":[63],"streptozocin":[65],"(90":[66],"mg/kg)":[67,73],"in":[68,94,105,135,156,166,178,205],"Long-Evans":[69],"Glibenclamide":[71],"(5":[72],"used":[75],"as":[76,215],"standard":[78],"agent.":[80,221],"result":[82],"indicated":[83,193],"that":[84],"after":[85,181],"oral":[86],"ingestion":[87],"21":[92,182],"days":[93,183],"rat,":[96],"significant":[98],"plasma":[99],"glucose":[100,104],"lowering":[101],"effect":[102],"(plasma":[103,133],"mmol/l,":[106],"Mean":[107,137],"\u00b1":[108,111,115,138,146,150],"SD;":[109],"8.81":[110],"1.22":[112],"vs.":[113,121,142,148],"3.57":[114],"3.38,":[116],"on":[117,186],"1st":[119],"day":[120],"22nddays,p":[122],"=":[123],".002)":[124],"improved.":[126],"It":[127,211],"also":[128],"enhanced":[129],"insulin":[130,134,219],"releasing":[131],"ng/ml,":[136],"SD:":[139],"group":[140,143,170],"1":[141],"3,":[144],"0.54":[145],"0.13":[147],"0.93":[149],"0.19;":[151],"p=0.001)":[152],"significantly":[154],"higher":[155],"treated":[159,168],"type":[160,187,206],"2":[161,188,207],"rats":[162],"(group":[163,171],"3)":[164],"than":[165],"water":[167],"control":[169],"1).":[172],"But":[173],"there":[174],"no":[176],"change":[177],"lipid":[179],"level":[180],"feeding":[185],"model":[189,209],"results":[192],"that,":[194],"nontoxic":[195],"seed":[201],"possesses":[202],"properties":[204],"seems":[212],"act":[214],"an":[216],"insulonomimetic":[217],"and/or":[218],"sensitizing":[220]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2021-10-11T00:00:00"}