{"id":"https://openalex.org/W3202393827","doi":null,"title":"Regulation of KCNQ1 and CFTR in Colorectal Cancer","display_name":"Regulation of KCNQ1 and CFTR in Colorectal Cancer","publication_year":2019,"publication_date":"2019-05-01","ids":{"openalex":"https://openalex.org/W3202393827","mag":"3202393827"},"language":"en","primary_location":{"id":"pmh:oai:conservancy.umn.edu:11299/206153","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11299/206153","pdf_url":"http://hdl.handle.net/11299/206153","source":{"id":"https://openalex.org/S4306402521","display_name":"University of Minnesota Digital Conservancy (University of Minnesota)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I130238516","host_organization_name":"University of Minnesota","host_organization_lineage":["https://openalex.org/I130238516"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11299/206153","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Rebecca Madden","orcid":"https://orcid.org/0000-0002-7788-6968","observed_orcids":["https://orcid.org/0000-0002-7788-6968"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rebecca Madden","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7788-6968","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8695999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8695999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.06199999898672104,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kcnq1","display_name":"KCNQ1","score":1.0},{"id":"https://openalex.org/keywords/cftr","display_name":"CFTR","score":0.9990000128746033},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9929999709129333},{"id":"https://openalex.org/keywords/ion-channel-modulation","display_name":"ion channel modulation","score":0.7929999828338623},{"id":"https://openalex.org/keywords/potassium-channels","display_name":"potassium channels","score":0.48399999737739563},{"id":"https://openalex.org/keywords/cystic-fibrosis-transmembrane-conductance-regulator","display_name":"cystic fibrosis transmembrane conductance regulator","score":0.8539999723434448}],"concepts":[{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6460215449333191},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4825591444969177},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4665054678916931},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.37184739112854004},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36509186029434204}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:conservancy.umn.edu:11299/206153","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11299/206153","pdf_url":"http://hdl.handle.net/11299/206153","source":{"id":"https://openalex.org/S4306402521","display_name":"University of Minnesota Digital Conservancy (University of Minnesota)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I130238516","host_organization_name":"University of Minnesota","host_organization_lineage":["https://openalex.org/I130238516"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or Dissertation"},{"id":"mag:3202393827","doi":null,"is_oa":false,"landing_page_url":"https://conservancy.umn.edu/bitstream/11299/206153/1/Madden_umn_0130M_20219.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:conservancy.umn.edu:11299/206153","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11299/206153","pdf_url":"http://hdl.handle.net/11299/206153","source":{"id":"https://openalex.org/S4306402521","display_name":"University of Minnesota Digital Conservancy (University of Minnesota)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I130238516","host_organization_name":"University of Minnesota","host_organization_lineage":["https://openalex.org/I130238516"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis or Dissertation"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3202393827.pdf","grobid_xml":"https://content.openalex.org/works/W3202393827.grobid-xml"},"referenced_works_count":82,"referenced_works":["https://openalex.org/W145015220","https://openalex.org/W217432650","https://openalex.org/W1526286057","https://openalex.org/W1597884041","https://openalex.org/W1655178001","https://openalex.org/W1973800261","https://openalex.org/W1975971473","https://openalex.org/W1982603620","https://openalex.org/W1983062454","https://openalex.org/W1987252871","https://openalex.org/W1988373579","https://openalex.org/W1999125098","https://openalex.org/W2001258296","https://openalex.org/W2004878973","https://openalex.org/W2007034789","https://openalex.org/W2010104346","https://openalex.org/W2010867021","https://openalex.org/W2020590257","https://openalex.org/W2023560061","https://openalex.org/W2025346950","https://openalex.org/W2027337701","https://openalex.org/W2027542963","https://openalex.org/W2030183705","https://openalex.org/W2040229638","https://openalex.org/W2042797183","https://openalex.org/W2059592231","https://openalex.org/W2059968749","https://openalex.org/W2065833903","https://openalex.org/W2068483283","https://openalex.org/W2096758563","https://openalex.org/W2097961915","https://openalex.org/W2098278242","https://openalex.org/W2100125385","https://openalex.org/W2103502575","https://openalex.org/W2104005622","https://openalex.org/W2107648723","https://openalex.org/W2110504545","https://openalex.org/W2115383660","https://openalex.org/W2117121254","https://openalex.org/W2118971690","https://openalex.org/W2128920102","https://openalex.org/W2140162975","https://openalex.org/W2144040104","https://openalex.org/W2155507705","https://openalex.org/W2159155233","https://openalex.org/W2161352411","https://openalex.org/W2162979342","https://openalex.org/W2163432887","https://openalex.org/W2167743029","https://openalex.org/W2171977041","https://openalex.org/W2234614402","https://openalex.org/W2277542958","https://openalex.org/W2283682956","https://openalex.org/W2321178059","https://openalex.org/W2322915906","https://openalex.org/W2332566578","https://openalex.org/W2336577217","https://openalex.org/W2416077975","https://openalex.org/W2461952548","https://openalex.org/W2465250101","https://openalex.org/W2470172036","https://openalex.org/W2510356564","https://openalex.org/W2510423734","https://openalex.org/W2516666988","https://openalex.org/W2517315109","https://openalex.org/W2537031737","https://openalex.org/W2553665580","https://openalex.org/W2561114892","https://openalex.org/W2594373254","https://openalex.org/W2604652125","https://openalex.org/W2609910134","https://openalex.org/W2612847272","https://openalex.org/W2624980219","https://openalex.org/W2665902468","https://openalex.org/W2789900268","https://openalex.org/W2790147790","https://openalex.org/W2790230715","https://openalex.org/W2904934792","https://openalex.org/W2909400148","https://openalex.org/W2950306742","https://openalex.org/W3106798016","https://openalex.org/W4211056322"],"related_works":["https://openalex.org/W2782554679","https://openalex.org/W984053647","https://openalex.org/W2787803424","https://openalex.org/W4392150727","https://openalex.org/W2604652125","https://openalex.org/W797727625","https://openalex.org/W2604896888","https://openalex.org/W4417200050","https://openalex.org/W7219232448","https://openalex.org/W2005459131"],"abstract_inverted_index":{"University":[0],"of":[1],"Minnesota":[2],"M.S.":[3],"thesis.":[4],"May":[5],"2019.":[6],"Major:":[7],"Integrated":[8],"Biosciences.":[9],"Advisors:":[10],"Patricia":[11],"Scott,":[12],"Robert":[13],"Cormier.":[14],"1":[15],"computer":[16],"file":[17],"(PDF);":[18],"v,":[19],"86":[20],"pages.":[21]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-10-11T00:00:00"}