{"id":"https://openalex.org/W3202209166","doi":"https://doi.org/10.3390/cosmetics8040092","title":"Genetic and Epigenetic Aspects of Skin Collagen Fiber Turnover and Functioning","display_name":"Genetic and Epigenetic Aspects of Skin Collagen Fiber Turnover and Functioning","publication_year":2021,"publication_date":"2021-09-29","ids":{"openalex":"https://openalex.org/W3202209166","doi":"https://doi.org/10.3390/cosmetics8040092","mag":"3202209166"},"language":"en","primary_location":{"id":"doi:10.3390/cosmetics8040092","doi":"https://doi.org/10.3390/cosmetics8040092","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cosmetics8040092","pdf_url":"https://www.mdpi.com/2079-9284/8/4/92/pdf?version=1632898786","source":{"id":"https://openalex.org/S2738608518","display_name":"Cosmetics","issn_l":"2079-9284","issn":["2079-9284"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cosmetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-9284/8/4/92/pdf?version=1632898786","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007153526","display_name":"\u041d. \u041d. \u041f\u043e\u0442\u0435\u043a\u0430\u0435\u0432","orcid":"https://orcid.org/0000-0002-9578-5490","observed_orcids":["https://orcid.org/0000-0002-9578-5490"]},"institutions":[{"id":"https://openalex.org/I337778094","display_name":"Pirogov Russian National Research Medical University","ror":"https://ror.org/018159086","country_code":"RU","type":"education","lineage":["https://openalex.org/I337778094","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Nikolay N. Potekaev","raw_affiliation_strings":["Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, Moscow 117997, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, Moscow 117997, Russia","institution_ids":["https://openalex.org/I337778094"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068704748","display_name":"Olga Borisovna Borzykh","orcid":"https://orcid.org/0000-0002-3651-4703","observed_orcids":["https://orcid.org/0000-0002-3651-4703"]},"institutions":[{"id":"https://openalex.org/I4210090231","display_name":"Krasnoyarsk State Medical University","ror":"https://ror.org/00b0jb681","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210090231"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Olga B. Borzykh","raw_affiliation_strings":["Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia"],"raw_orcid":"https://orcid.org/0000-0002-3651-4703","affiliations":[{"raw_affiliation_string":"Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia","institution_ids":["https://openalex.org/I4210090231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015907625","display_name":"German V. Medvedev","orcid":"https://orcid.org/0000-0001-6064-4164","observed_orcids":["https://orcid.org/0000-0001-6064-4164"]},"institutions":[{"id":"https://openalex.org/I4210099506","display_name":"Russian Scientific Research Institute of Traumatology and Orthopedics named after R.R. Vreden","ror":"https://ror.org/014rxe718","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210099506"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"German V. Medvedev","raw_affiliation_strings":["Department of Hand Surgery with Microsurgical Equipment, Vreden National Medical Research Center of Traumatology and Orthopedics, St. Petersburg 195427, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hand Surgery with Microsurgical Equipment, Vreden National Medical Research Center of Traumatology and Orthopedics, St. Petersburg 195427, Russia","institution_ids":["https://openalex.org/I4210099506"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071876358","display_name":"\u041c. \u041c. \u041f\u0435\u0442\u0440\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0002-8493-0058","observed_orcids":["https://orcid.org/0000-0002-8493-0058"]},"institutions":[{"id":"https://openalex.org/I4210090231","display_name":"Krasnoyarsk State Medical University","ror":"https://ror.org/00b0jb681","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210090231"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Marina M. Petrova","raw_affiliation_strings":["Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia","institution_ids":["https://openalex.org/I4210090231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070987216","display_name":"Oksana Aleksandrovna Gavrilyuk","orcid":"https://orcid.org/0000-0002-9343-6633","observed_orcids":["https://orcid.org/0000-0002-9343-6633"]},"institutions":[{"id":"https://openalex.org/I4210090231","display_name":"Krasnoyarsk State Medical University","ror":"https://ror.org/00b0jb681","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210090231"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Oksana A. Gavrilyuk","raw_affiliation_strings":["Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia"],"raw_orcid":"https://orcid.org/0000-0002-9343-6633","affiliations":[{"raw_affiliation_string":"Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia","institution_ids":["https://openalex.org/I4210090231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076655361","display_name":"Elena I. Karpova","orcid":"https://orcid.org/0000-0003-0510-1022","observed_orcids":["https://orcid.org/0000-0003-0510-1022"]},"institutions":[{"id":"https://openalex.org/I337778094","display_name":"Pirogov Russian National Research Medical University","ror":"https://ror.org/018159086","country_code":"RU","type":"education","lineage":["https://openalex.org/I337778094","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Elena I. Karpova","raw_affiliation_strings":["Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, Moscow 117997, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, Moscow 117997, Russia","institution_ids":["https://openalex.org/I337778094"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033000819","display_name":"Vera V. Trefilova","orcid":"https://orcid.org/0000-0002-4378-1308","observed_orcids":["https://orcid.org/0000-0002-4378-1308"]},"institutions":[{"id":"https://openalex.org/I2799899041","display_name":"St.Petersburg V.M.Bekhterev Psychoneurological Research Institute","ror":"https://ror.org/005e2bj09","country_code":"RU","type":"facility","lineage":["https://openalex.org/I2799899041"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vera V. Trefilova","raw_affiliation_strings":["Center of Personalized Psychiatry and Neurology, V. M. Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg 192019, Russia"],"raw_orcid":"https://orcid.org/0000-0002-4378-1308","affiliations":[{"raw_affiliation_string":"Center of Personalized Psychiatry and Neurology, V. M. Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg 192019, Russia","institution_ids":["https://openalex.org/I2799899041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045444312","display_name":"Olga Mikhailovna Demina","orcid":"https://orcid.org/0000-0001-9406-2787","observed_orcids":["https://orcid.org/0000-0001-9406-2787"]},"institutions":[{"id":"https://openalex.org/I337778094","display_name":"Pirogov Russian National Research Medical University","ror":"https://ror.org/018159086","country_code":"RU","type":"education","lineage":["https://openalex.org/I337778094","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Olga M. Demina","raw_affiliation_strings":["Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, Moscow 117997, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, Moscow 117997, Russia","institution_ids":["https://openalex.org/I337778094"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058246777","display_name":"Tatiana E. Popova","orcid":"https://orcid.org/0000-0003-1062-1540","observed_orcids":["https://orcid.org/0000-0003-1062-1540"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tatiana E. Popova","raw_affiliation_strings":["Department of Epidemiology of Non-Infectious Diseases, Yakutsk Scientific Center for Complex Problems, Yakutsk 677000, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology of Non-Infectious Diseases, Yakutsk Scientific Center for Complex Problems, Yakutsk 677000, Russia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033552717","display_name":"Natalia Alekseevna Shnayder","orcid":"https://orcid.org/0000-0002-2840-837X","observed_orcids":["https://orcid.org/0000-0002-2840-837X"]},"institutions":[{"id":"https://openalex.org/I2799899041","display_name":"St.Petersburg V.M.Bekhterev Psychoneurological Research Institute","ror":"https://ror.org/005e2bj09","country_code":"RU","type":"facility","lineage":["https://openalex.org/I2799899041"]},{"id":"https://openalex.org/I4210090231","display_name":"Krasnoyarsk State Medical University","ror":"https://ror.org/00b0jb681","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210090231"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Natalia A. Shnayder","raw_affiliation_strings":["Center of Personalized Psychiatry and Neurology, V. M. Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg 192019, Russia","Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia"],"raw_orcid":"https://orcid.org/0000-0002-2840-837X","affiliations":[{"raw_affiliation_string":"Center of Personalized Psychiatry and Neurology, V. M. Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg 192019, Russia","institution_ids":["https://openalex.org/I2799899041"]},{"raw_affiliation_string":"Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia","institution_ids":["https://openalex.org/I4210090231"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5033552717","https://openalex.org/A5068704748"],"corresponding_institution_ids":["https://openalex.org/I2799899041","https://openalex.org/I4210090231"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1512},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1512},"fwci":0.6642,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.55576899,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"8","issue":"4","first_page":"92","last_page":"92"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12085","display_name":"Collagen: Extraction and Characterization","score":0.3970000147819519,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12085","display_name":"Collagen: Extraction and Characterization","score":0.3970000147819519,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11310","display_name":"Connective tissue disorders research","score":0.3059000074863434,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.15559999644756317,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/skin-collagen","display_name":"skin collagen","score":0.6380000114440918},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.7860000133514404},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8799999952316284},{"id":"https://openalex.org/keywords/collagen-types","display_name":"collagen types","score":0.7269999980926514},{"id":"https://openalex.org/keywords/collagenopathies","display_name":"collagenopathies","score":0.6729999780654907},{"id":"https://openalex.org/keywords/skin-aging","display_name":"skin aging","score":0.6620000004768372},{"id":"https://openalex.org/keywords/skin-laxity","display_name":"skin laxity","score":0.6460000276565552},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.7289482951164246},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6906817555427551},{"id":"https://openalex.org/C2993866533","wikidata":"https://www.wikidata.org/wiki/Q26868","display_name":"Collagen fiber","level":2,"score":0.6895537376403809},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.6475006937980652},{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.5129294395446777},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4473898112773895},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.42659685015678406},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.365998238325119},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2763885259628296},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23410436511039734},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1766752004623413},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1544090211391449},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14174878597259521}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3390/cosmetics8040092","doi":"https://doi.org/10.3390/cosmetics8040092","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cosmetics8040092","pdf_url":"https://www.mdpi.com/2079-9284/8/4/92/pdf?version=1632898786","source":{"id":"https://openalex.org/S2738608518","display_name":"Cosmetics","issn_l":"2079-9284","issn":["2079-9284"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cosmetics","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:9669b0cdc5ca405c997a10595fd7b5b8","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9669b0cdc5ca405c997a10595fd7b5b8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cosmetics, Vol 8, Iss 4, p 92 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/cosmetics8040092","doi":"https://doi.org/10.3390/cosmetics8040092","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cosmetics8040092","pdf_url":"https://www.mdpi.com/2079-9284/8/4/92/pdf?version=1632898786","source":{"id":"https://openalex.org/S2738608518","display_name":"Cosmetics","issn_l":"2079-9284","issn":["2079-9284"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cosmetics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3202209166.pdf","grobid_xml":"https://content.openalex.org/works/W3202209166.grobid-xml"},"referenced_works_count":109,"referenced_works":["https://openalex.org/W1156636126","https://openalex.org/W1870255478","https://openalex.org/W1973059210","https://openalex.org/W1988022977","https://openalex.org/W2004098988","https://openalex.org/W2011984901","https://openalex.org/W2020583733","https://openalex.org/W2023793692","https://openalex.org/W2024264687","https://openalex.org/W2045639763","https://openalex.org/W2072576191","https://openalex.org/W2084773197","https://openalex.org/W2095998281","https://openalex.org/W2119627031","https://openalex.org/W2121317746","https://openalex.org/W2168869876","https://openalex.org/W2259256124","https://openalex.org/W2294045289","https://openalex.org/W2325212255","https://openalex.org/W2466975552","https://openalex.org/W2531740726","https://openalex.org/W2572367037","https://openalex.org/W2582735211","https://openalex.org/W2590019738","https://openalex.org/W2591751933","https://openalex.org/W2599889833","https://openalex.org/W2607704951","https://openalex.org/W2608566710","https://openalex.org/W2608853245","https://openalex.org/W2612434055","https://openalex.org/W2615428716","https://openalex.org/W2735875576","https://openalex.org/W2742883612","https://openalex.org/W2743764518","https://openalex.org/W2748656499","https://openalex.org/W2750481248","https://openalex.org/W2751573301","https://openalex.org/W2765723837","https://openalex.org/W2766229657","https://openalex.org/W2781280912","https://openalex.org/W2791975514","https://openalex.org/W2793047228","https://openalex.org/W2794367096","https://openalex.org/W2795182622","https://openalex.org/W2795473923","https://openalex.org/W2797786463","https://openalex.org/W2798023285","https://openalex.org/W2800155899","https://openalex.org/W2800438504","https://openalex.org/W2807083018","https://openalex.org/W2808438085","https://openalex.org/W2811028872","https://openalex.org/W2816723802","https://openalex.org/W2883349899","https://openalex.org/W2895487437","https://openalex.org/W2900047541","https://openalex.org/W2914156600","https://openalex.org/W2921437380","https://openalex.org/W2925063645","https://openalex.org/W2932503900","https://openalex.org/W2939003387","https://openalex.org/W2942090617","https://openalex.org/W2944617715","https://openalex.org/W2944916956","https://openalex.org/W2947176488","https://openalex.org/W2949082334","https://openalex.org/W2953612472","https://openalex.org/W2954987929","https://openalex.org/W2955015434","https://openalex.org/W2955764133","https://openalex.org/W2964745057","https://openalex.org/W2965391757","https://openalex.org/W2966230244","https://openalex.org/W2967374206","https://openalex.org/W2969875971","https://openalex.org/W2972310575","https://openalex.org/W2973191272","https://openalex.org/W2979797563","https://openalex.org/W2981895502","https://openalex.org/W2982401539","https://openalex.org/W2984648960","https://openalex.org/W2995192865","https://openalex.org/W3009025838","https://openalex.org/W3019034047","https://openalex.org/W3021358866","https://openalex.org/W3022615893","https://openalex.org/W3026378393","https://openalex.org/W3030413515","https://openalex.org/W3032707245","https://openalex.org/W3079438341","https://openalex.org/W3089213956","https://openalex.org/W3089289366","https://openalex.org/W3092938840","https://openalex.org/W3094271951","https://openalex.org/W3104200197","https://openalex.org/W3109266820","https://openalex.org/W3112545085","https://openalex.org/W3115625794","https://openalex.org/W3126739473","https://openalex.org/W3130456863","https://openalex.org/W3133728387","https://openalex.org/W3136479945","https://openalex.org/W3138005692","https://openalex.org/W3156174958","https://openalex.org/W3158399646","https://openalex.org/W3177027559","https://openalex.org/W3204008252","https://openalex.org/W4211179398","https://openalex.org/W6748732979"],"related_works":["https://openalex.org/W4306643614","https://openalex.org/W4313228611","https://openalex.org/W4409358703","https://openalex.org/W3041757719","https://openalex.org/W4412707054","https://openalex.org/W4292189154","https://openalex.org/W4307485319","https://openalex.org/W4239954385","https://openalex.org/W2155238230","https://openalex.org/W6217749"],"abstract_inverted_index":{"One":[0],"of":[1,6,52,67,74,96,111,127,130,139],"the":[2,7,26,49,53,68,80,92,105,109,125,134,137,152],"most":[3,153],"important":[4,85],"functions":[5,126],"skin,":[8],"i.e.,":[9],"protection":[10],"from":[11],"mechanical":[12,50],"damage,":[13],"is":[14,32,84],"ensured":[15],"by":[16],"collagen":[17,57,118,141],"fibers":[18],"and":[19,65,70,88,94,103,113,156],"their":[20],"interaction":[21],"with":[22],"other":[23],"elements":[24],"in":[25,48,116,133],"extracellular":[27],"matrix.":[28],"Collagen":[29],"fiber":[30,119],"turnover":[31],"a":[33,40,46],"complex":[34],"multi-stage":[35],"process.":[36],"At":[37],"each":[38],"stage,":[39],"disruption":[41],"may":[42],"occur,":[43],"leading":[44],"to":[45,79,90,146],"decrease":[47],"properties":[51],"connective":[54],"tissue.":[55],"Clinically,":[56],"formation":[58,142],"disorders":[59],"manifest":[60],"themselves":[61],"as":[62,71],"increased":[63],"flabbiness":[64],"looseness":[66],"skin":[69,117],"early":[72],"signs":[73],"facial":[75],"aging.":[76],"In":[77,98],"addition":[78],"clinical":[81],"picture,":[82],"it":[83],"for":[86],"cosmetologists":[87],"dermatologists":[89],"understand":[91],"etiology":[93,138],"pathogenesis":[95],"collagenopathies.":[97],"our":[99],"review,":[100],"we":[101,122],"summarized":[102],"systematized":[104],"available":[106],"information":[107],"concerning":[108],"role":[110],"genetic":[112],"epigenetic":[114],"factors":[115],"turnover.":[120],"Furthermore,":[121],"focused":[123],"on":[124],"different":[128],"types":[129],"collagens":[131],"present":[132],"skin.":[135],"Understanding":[136],"impaired":[140],"can":[143],"allow":[144],"doctors":[145],"prescribe":[147],"pathogenetically":[148],"based":[149],"treatments,":[150],"achieve":[151],"effective":[154],"results,":[155],"minimize":[157],"adverse":[158],"reactions.":[159]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2021-10-11T00:00:00"}