{"id":"https://openalex.org/W3202029706","doi":null,"title":"A Macrophage Rac1-IL1B Signaling Axis Directs Atherosclerotic Calcification","display_name":"A Macrophage Rac1-IL1B Signaling Axis Directs Atherosclerotic Calcification","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3202029706","mag":"3202029706"},"language":"en","primary_location":{"id":"mag:3202029706","doi":null,"is_oa":false,"landing_page_url":"https://repository.library.brown.edu/studio/item/bdr:3dmmuzn5/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035534538","display_name":"Joshua M. Berus","orcid":"https://orcid.org/0000-0003-0473-125X","observed_orcids":["https://orcid.org/0000-0003-0473-125X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Joshua Berus","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5035534538"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rac1","display_name":"Rac1","score":0.7620000243186951},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8679999709129333},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.9419999718666077},{"id":"https://openalex.org/keywords/atherosclerotic-calcification","display_name":"atherosclerotic calcification","score":0.9340000152587891},{"id":"https://openalex.org/keywords/rho-gtpase-signaling","display_name":"Rho GTPase signaling","score":0.7020000219345093},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.3569999933242798},{"id":"https://openalex.org/keywords/vascular-calcification","display_name":"vascular calcification","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5917564034461975},{"id":"https://openalex.org/C2779717556","wikidata":"https://www.wikidata.org/wiki/Q15325735","display_name":"RAC1","level":3,"score":0.5876498818397522},{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.5407495498657227},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4250299334526062},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4213744103908539},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3346884250640869},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3298991918563843},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31053391098976135},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23655933141708374},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18303868174552917},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3202029706","doi":null,"is_oa":false,"landing_page_url":"https://repository.library.brown.edu/studio/item/bdr:3dmmuzn5/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4312436621","https://openalex.org/W2892211344","https://openalex.org/W2303986395","https://openalex.org/W4387270147","https://openalex.org/W2551261660","https://openalex.org/W3004243791","https://openalex.org/W3177105328","https://openalex.org/W2999045533","https://openalex.org/W3087409649","https://openalex.org/W2922486294"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2021-10-11T00:00:00"}