{"id":"https://openalex.org/W3200499211","doi":"https://doi.org/10.3949/ccjm.88a.ccc080","title":"COVID-19 in older adults","display_name":"COVID-19 in older adults","publication_year":2021,"publication_date":"2021-09-16","ids":{"openalex":"https://openalex.org/W3200499211","doi":"https://doi.org/10.3949/ccjm.88a.ccc080","mag":"3200499211","pmid":"https://pubmed.ncbi.nlm.nih.gov/34531255"},"language":"en","primary_location":{"id":"doi:10.3949/ccjm.88a.ccc080","doi":"https://doi.org/10.3949/ccjm.88a.ccc080","is_oa":true,"landing_page_url":"https://doi.org/10.3949/ccjm.88a.ccc080","pdf_url":"https://www.ccjm.org/content/ccjom/early/2021/09/14/ccjm.88a.ccc080.full.pdf","source":{"id":"https://openalex.org/S20761018","display_name":"Cleveland Clinic Journal of Medicine","issn_l":"0891-1150","issn":["0891-1150","1939-2869"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315641","host_organization_name":"Cleveland Clinic","host_organization_lineage":["https://openalex.org/P4310315641"],"host_organization_lineage_names":["Cleveland Clinic"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cleveland Clinic Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.ccjm.org/content/ccjom/early/2021/09/14/ccjm.88a.ccc080.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031698060","display_name":"Saket A. Saxena","orcid":"https://orcid.org/0000-0003-4084-7954","observed_orcids":["https://orcid.org/0000-0003-4084-7954"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saket Saxena","raw_affiliation_strings":["Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, OH SAXENAS@ccf.org","Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, OH SAXENAS@ccf.org","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052344686","display_name":"Ardeshir Z. Hashmi","orcid":"https://orcid.org/0000-0001-5351-9146","observed_orcids":["https://orcid.org/0000-0001-5351-9146"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ardeshir Z. Hashmi","raw_affiliation_strings":["Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1316902750"],"apc_list":null,"apc_paid":null,"fwci":0.4253,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.65620438,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":1.0},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9900000095367432},{"id":"https://openalex.org/keywords/atypical-presentation","display_name":"atypical presentation","score":0.8220000267028809},{"id":"https://openalex.org/keywords/immune-dysregulation","display_name":"immune dysregulation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/chronic-comorbidities","display_name":"chronic comorbidities","score":0.9610000252723694},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.8930000066757202},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.9810000061988831},{"id":"https://openalex.org/keywords/treatment-strategy","display_name":"treatment options","score":0.8080000281333923}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9127763509750366},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.8016354441642761},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.5673615336418152},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5566255450248718},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.45400309562683105},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43593505024909973},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.4293113648891449},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3885958194732666},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.23643308877944946},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.1344330906867981},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13143163919448853},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09410035610198975},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.07949712872505188},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.06483146548271179},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3949/ccjm.88a.ccc080","doi":"https://doi.org/10.3949/ccjm.88a.ccc080","is_oa":true,"landing_page_url":"https://doi.org/10.3949/ccjm.88a.ccc080","pdf_url":"https://www.ccjm.org/content/ccjom/early/2021/09/14/ccjm.88a.ccc080.full.pdf","source":{"id":"https://openalex.org/S20761018","display_name":"Cleveland Clinic Journal of Medicine","issn_l":"0891-1150","issn":["0891-1150","1939-2869"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315641","host_organization_name":"Cleveland Clinic","host_organization_lineage":["https://openalex.org/P4310315641"],"host_organization_lineage_names":["Cleveland Clinic"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cleveland Clinic Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:34531255","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34531255","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cleveland Clinic journal of medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3949/ccjm.88a.ccc080","doi":"https://doi.org/10.3949/ccjm.88a.ccc080","is_oa":true,"landing_page_url":"https://doi.org/10.3949/ccjm.88a.ccc080","pdf_url":"https://www.ccjm.org/content/ccjom/early/2021/09/14/ccjm.88a.ccc080.full.pdf","source":{"id":"https://openalex.org/S20761018","display_name":"Cleveland Clinic Journal of Medicine","issn_l":"0891-1150","issn":["0891-1150","1939-2869"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315641","host_organization_name":"Cleveland Clinic","host_organization_lineage":["https://openalex.org/P4310315641"],"host_organization_lineage_names":["Cleveland Clinic"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cleveland Clinic Journal of Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3200499211.pdf","grobid_xml":"https://content.openalex.org/works/W3200499211.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1507573241","https://openalex.org/W2051719302","https://openalex.org/W2077411129","https://openalex.org/W2113945548","https://openalex.org/W2149938672","https://openalex.org/W2765385887","https://openalex.org/W2971414200","https://openalex.org/W3005206095","https://openalex.org/W3008827533","https://openalex.org/W3013749134","https://openalex.org/W3015925195","https://openalex.org/W3020551862","https://openalex.org/W3021126430","https://openalex.org/W3026764413","https://openalex.org/W3035241576","https://openalex.org/W3042998368","https://openalex.org/W3043796081","https://openalex.org/W3083601077","https://openalex.org/W3091932000","https://openalex.org/W3099899462","https://openalex.org/W3106275948","https://openalex.org/W3131308734","https://openalex.org/W3132436110","https://openalex.org/W3161768951","https://openalex.org/W6785965263"],"related_works":["https://openalex.org/W4205696052","https://openalex.org/W3040562530","https://openalex.org/W4410190669","https://openalex.org/W3209834501","https://openalex.org/W4221013236","https://openalex.org/W4383668077","https://openalex.org/W3032629753","https://openalex.org/W4220755310","https://openalex.org/W3087327472","https://openalex.org/W4400687404"],"abstract_inverted_index":{"The":[0],"impact":[1,51],"of":[2,26,28,48,52,62],"COVID-19":[3,22],"varies":[4],"by":[5,21,71],"age":[6],"group,":[7],"and":[8,30,44,74],"it":[9],"has":[10],"become":[11],"clear":[12],"that":[13],"individuals":[14],"over":[15],"65":[16],"years":[17],"are":[18],"disproportionately":[19],"impacted":[20],"both":[23],"in":[24,34],"terms":[25],"severity":[27],"illness":[29,63],"mortality.":[31],"Atypical":[32],"presentations":[33,61],"older":[35,65],"adults":[36],"may":[37],"result":[38],"from":[39],"pathophysiologic":[40],"changes":[41],"during":[42],"aging":[43],"immune":[45],"dysregulation":[46],"because":[47],"the":[49,58,67],"cumulative":[50],"chronic":[53],"comorbidities.":[54],"Herein":[55],"we":[56],"review":[57],"different":[59],"clinical":[60],"for":[64,76],"adults,":[66],"unique":[68],"challenges":[69],"faced":[70],"this":[72],"population,":[73],"strategies":[75],"treatment.":[77]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-09-27T00:00:00"}