{"id":"https://openalex.org/W3196524906","doi":"https://doi.org/10.1039/d1nr04211d","title":"Ultrasound augments on-demand breast tumor radiosensitization and apoptosis through a tri-responsive combinatorial delivery theranostic platform","display_name":"Ultrasound augments on-demand breast tumor radiosensitization and apoptosis through a tri-responsive combinatorial delivery theranostic platform","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3196524906","doi":"https://doi.org/10.1039/d1nr04211d","mag":"3196524906","pmid":"https://pubmed.ncbi.nlm.nih.gov/34622906"},"language":"en","primary_location":{"id":"doi:10.1039/d1nr04211d","doi":"https://doi.org/10.1039/d1nr04211d","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d1nr04211d","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-3","ki-jl-2","medline","norway-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078830681","display_name":"Prateek Bhardwaj","orcid":"https://orcid.org/0000-0001-5546-7829","observed_orcids":["https://orcid.org/0000-0001-5546-7829"]},"institutions":[{"id":"https://openalex.org/I162827531","display_name":"Indian Institute of Technology Bombay","ror":"https://ror.org/02qyf5152","country_code":"IN","type":"education","lineage":["https://openalex.org/I162827531"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Prateek Bhardwaj","raw_affiliation_strings":["Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, Maharashtra, India"],"raw_orcid":"https://orcid.org/0000-0001-5546-7829","affiliations":[{"raw_affiliation_string":"Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, Maharashtra, India","institution_ids":["https://openalex.org/I162827531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063174317","display_name":"Jayant Sastri Goda","orcid":"https://orcid.org/0000-0002-3915-8927","observed_orcids":["https://orcid.org/0000-0002-3915-8927"]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jayant Sastri Goda","raw_affiliation_strings":["Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":"https://orcid.org/0000-0002-3915-8927","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Venkatesh Pai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Venkatesh Pai","raw_affiliation_strings":["Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112576972","display_name":"Pradip Chaudhari","orcid":"https://orcid.org/0000-0002-6792-7658","observed_orcids":["https://orcid.org/0000-0002-6792-7658"]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pradip Chaudhari","raw_affiliation_strings":["Animal house facility, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal house facility, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035562262","display_name":"Bhabani Shankar Mohanty","orcid":"https://orcid.org/0000-0003-3387-2545","observed_orcids":["https://orcid.org/0000-0003-3387-2545"]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bhabani Mohanty","raw_affiliation_strings":["Animal house facility, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal house facility, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014355046","display_name":"Trupti Pai","orcid":"https://orcid.org/0000-0001-5160-3897","observed_orcids":["https://orcid.org/0000-0001-5160-3897"]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Trupti Pai","raw_affiliation_strings":["Department of Pathology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065964105","display_name":"Komal Vishwakarma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Komal Vishwakarma","raw_affiliation_strings":["Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057973390","display_name":"Rahul A. Thorat","orcid":"https://orcid.org/0000-0001-5059-0342","observed_orcids":["https://orcid.org/0000-0001-5059-0342"]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rahul Thorat","raw_affiliation_strings":["Animal house facility, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal house facility, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087015391","display_name":"Tabassum Wadasadawala","orcid":"https://orcid.org/0000-0003-2167-420X","observed_orcids":["https://orcid.org/0000-0003-2167-420X","https://orcid.org/0000-0002-3711-2618"]},"institutions":[{"id":"https://openalex.org/I200207707","display_name":"Homi Bhabha National Institute","ror":"https://ror.org/02bv3zr67","country_code":"IN","type":"education","lineage":["https://openalex.org/I200207707"]},{"id":"https://openalex.org/I2800098698","display_name":"Tata Memorial Hospital","ror":"https://ror.org/010842375","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2800098698"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Tabassum Wadasadawala","raw_affiliation_strings":["Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India"],"raw_orcid":"https://orcid.org/0000-0003-2167-420X","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Tata Memorial Centre, Mumbai, & Homi Bhabha National Institute, Maharashtra, India","institution_ids":["https://openalex.org/I200207707","https://openalex.org/I2800098698"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064538692","display_name":"Rinti Banerjee","orcid":"https://orcid.org/0000-0002-6400-5906","observed_orcids":["https://orcid.org/0000-0002-6400-5906","https://orcid.org/0000-0002-5863-436X","https://orcid.org/0000-0003-2998-8852"]},"institutions":[{"id":"https://openalex.org/I162827531","display_name":"Indian Institute of Technology Bombay","ror":"https://ror.org/02qyf5152","country_code":"IN","type":"education","lineage":["https://openalex.org/I162827531"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Rinti Banerjee","raw_affiliation_strings":["Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, Maharashtra, India"],"raw_orcid":"https://orcid.org/0000-0002-6400-5906","affiliations":[{"raw_affiliation_string":"Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, Maharashtra, India","institution_ids":["https://openalex.org/I162827531"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5064538692","https://openalex.org/A5078830681","https://openalex.org/A5087015391"],"corresponding_institution_ids":["https://openalex.org/I162827531","https://openalex.org/I200207707","https://openalex.org/I2800098698"],"apc_list":null,"apc_paid":null,"fwci":0.7027,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.6295328,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"13","issue":"40","first_page":"17077","last_page":"17092"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.4771000146865845,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.4771000146865845,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.40139999985694885,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.07649999856948853,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrasound","display_name":"ultrasound","score":0.41200000047683716},{"id":"https://openalex.org/keywords/breast-tumors","display_name":"breast tumors","score":0.7009999752044678},{"id":"https://openalex.org/keywords/radiosensitization","display_name":"radiosensitization","score":0.9879999756813049},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9539999961853027},{"id":"https://openalex.org/keywords/paclitaxel","display_name":"paclitaxel","score":0.8790000081062317},{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.9860000014305115},{"id":"https://openalex.org/keywords/nanotheranostics","display_name":"nanotheranostics","score":0.675000011920929},{"id":"https://openalex.org/keywords/chemoradiotherapy","display_name":"chemoradiotherapy","score":0.8149999976158142},{"id":"https://openalex.org/keywords/pet-ct-imaging","display_name":"PET/CT imaging","score":0.8529999852180481},{"id":"https://openalex.org/keywords/tumor-microvessel-density","display_name":"tumor microvessel density","score":0.8790000081062317},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.5870000123977661},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.3580000102519989}],"concepts":[{"id":"https://openalex.org/C2777292972","wikidata":"https://www.wikidata.org/wiki/Q423762","display_name":"Paclitaxel","level":3,"score":0.7339847087860107},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.677638590335846},{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.6056874394416809},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5678392648696899},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5417606830596924},{"id":"https://openalex.org/C2780110267","wikidata":"https://www.wikidata.org/wiki/Q7843332","display_name":"Triple-negative breast cancer","level":4,"score":0.540496826171875},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.510235071182251},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.47062376141548157},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.43282550573349},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.40833690762519836},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3154140114784241},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2684435248374939},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.23401716351509094},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19637596607208252},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1491020917892456},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07622981071472168},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072078","descriptor_name":"Positron Emission Tomography Computed Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072078","descriptor_name":"Positron Emission Tomography Computed Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072078","descriptor_name":"Positron Emission Tomography Computed Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016513","descriptor_name":"Mice, SCID","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016513","descriptor_name":"Mice, SCID","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016513","descriptor_name":"Mice, SCID","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016688","descriptor_name":"Mice, Inbred NOD","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016688","descriptor_name":"Mice, Inbred NOD","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016688","descriptor_name":"Mice, Inbred NOD","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064726","descriptor_name":"Triple Negative Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D064726","descriptor_name":"Triple Negative Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D064726","descriptor_name":"Triple Negative Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D064726","descriptor_name":"Triple Negative Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D064726","descriptor_name":"Triple Negative Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D064726","descriptor_name":"Triple Negative Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/d1nr04211d","doi":"https://doi.org/10.1039/d1nr04211d","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d1nr04211d","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-3","ki-jl-2","medline","norway-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},{"id":"pmid:34622906","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34622906","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7099999785423279}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320335498","display_name":"Tata Memorial Centre","ror":"https://ror.org/010842375"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W1965887310","https://openalex.org/W1977686559","https://openalex.org/W1984389010","https://openalex.org/W1993544519","https://openalex.org/W2000610587","https://openalex.org/W2006262026","https://openalex.org/W2012282022","https://openalex.org/W2033274910","https://openalex.org/W2033999645","https://openalex.org/W2045605237","https://openalex.org/W2053352141","https://openalex.org/W2070672521","https://openalex.org/W2079993760","https://openalex.org/W2087266891","https://openalex.org/W2105256758","https://openalex.org/W2129067399","https://openalex.org/W2129397604","https://openalex.org/W2138215047","https://openalex.org/W2158809810","https://openalex.org/W2172024684","https://openalex.org/W2268788143","https://openalex.org/W2272762281","https://openalex.org/W2286779154","https://openalex.org/W2297044638","https://openalex.org/W2331647891","https://openalex.org/W2402636472","https://openalex.org/W2413689110","https://openalex.org/W2417259144","https://openalex.org/W2426156582","https://openalex.org/W2463142429","https://openalex.org/W2520458702","https://openalex.org/W2523464825","https://openalex.org/W2534733043","https://openalex.org/W2564809101","https://openalex.org/W2569746211","https://openalex.org/W2574215416","https://openalex.org/W2582457750","https://openalex.org/W2659186398","https://openalex.org/W2752562863","https://openalex.org/W2761628918","https://openalex.org/W2768413943","https://openalex.org/W2792817321","https://openalex.org/W2793545474","https://openalex.org/W2800579137","https://openalex.org/W2807358321","https://openalex.org/W2887176656","https://openalex.org/W2887850450","https://openalex.org/W2893671817","https://openalex.org/W2901113618","https://openalex.org/W2916045508","https://openalex.org/W2922407185","https://openalex.org/W2967517338","https://openalex.org/W3016600453","https://openalex.org/W3016649999","https://openalex.org/W3087464759","https://openalex.org/W3090937986","https://openalex.org/W3093268693","https://openalex.org/W3093593152","https://openalex.org/W3128646645","https://openalex.org/W4211005384","https://openalex.org/W4211032970","https://openalex.org/W4232044723","https://openalex.org/W4255762755","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2589512255","https://openalex.org/W2887769962","https://openalex.org/W4379468034","https://openalex.org/W1984122016","https://openalex.org/W2117116660","https://openalex.org/W1971462710","https://openalex.org/W4360797513","https://openalex.org/W2047540814","https://openalex.org/W2736387565","https://openalex.org/W2385388487"],"abstract_inverted_index":{"chemoradiotherapeutic":[0],"efficacy":[1],"of":[2,16,39,63],"paclitaxel":[3],"upon":[4],"loading":[5],"into":[6],"nano-conjugates.":[7],"This":[8],"gets":[9],"further":[10],"enhanced":[11],"by":[12,20,36],"the":[13,29,37,50,59],"concurrent":[14],"pulse":[15],"ultrasound,":[17,44],"as":[18,70,72],"confirmed":[19],"PET-CT":[21],"imaging,":[22],"along":[23,45],"with":[24,46],"a":[25,47],"significant":[26],"improvement":[27],"in":[28,49],"mice":[30],"survival.":[31],"The":[32],"quadrapeutic":[33],"apoptotic":[34],"effect":[35],"combination":[38],"paclitaxel,":[40],"curcumin,":[41],"radiation,":[42],"and":[43,54],"reduction":[48],"tumor":[51],"microvessel":[52],"density":[53],"cell":[55],"proliferation":[56],"marker,":[57],"confers":[58],"broad":[60],"chemo-radiotherapeutic":[61],"potential":[62],"this":[64],"regimen":[65],"for":[66],"radio-responsive":[67],"solid":[68],"tumors,":[69],"well":[71],"metastatic":[73],"niches.":[74]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5}],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2025-10-10T00:00:00"}