{"id":"https://openalex.org/W3193045461","doi":null,"title":"Application value of goal-directed fluid therapy with ERAS in patients undergoing radical lung cancer surgery.","display_name":"Application value of goal-directed fluid therapy with ERAS in patients undergoing radical lung cancer surgery.","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3193045461","mag":"3193045461","pmid":"https://pubmed.ncbi.nlm.nih.gov/34377304","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8340232"},"language":"en","primary_location":{"id":"pmid:34377304","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34377304","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8340232/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101678734","display_name":"Xianghui Wang","orcid":"https://orcid.org/0009-0009-8046-2793","observed_orcids":["https://orcid.org/0009-0009-8046-2793"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xianghui Wang","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100461456","display_name":"Na Wang","orcid":"https://orcid.org/0000-0003-4489-7756","observed_orcids":["https://orcid.org/0000-0003-4489-7756"]},"institutions":[{"id":"https://openalex.org/I4405269505","display_name":"The First People's Hospital of Shuangliu District","ror":"https://ror.org/04cjrj888","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4405269505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Na Wang","raw_affiliation_strings":["Department of Anesthesia Operation, The First People's Hospital of Shuangliu District, Chengdu (West China Airport Hospital of Sichuan University) Chengdu 610200, Sichuan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia Operation, The First People's Hospital of Shuangliu District, Chengdu (West China Airport Hospital of Sichuan University) Chengdu 610200, Sichuan Province, China","institution_ids":["https://openalex.org/I4405269505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100762075","display_name":"Xinbo Wang","orcid":"https://orcid.org/0000-0001-8524-9662","observed_orcids":["https://orcid.org/0000-0001-8524-9662"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinbo Wang","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101909261","display_name":"Xiaona Wei","orcid":"https://orcid.org/0000-0003-1954-4246","observed_orcids":["https://orcid.org/0000-0003-1954-4246"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaona Wei","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101196914","display_name":"Manman Ma","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Manman Ma","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100970296","display_name":"Yan Sun","orcid":"https://orcid.org/0009-0005-9437-8702","observed_orcids":["https://orcid.org/0009-0005-9437-8702"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yan Sun","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038205407","display_name":"Danqi Ren","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Danqi Ren","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046777351","display_name":"Yanan Liu","orcid":"https://orcid.org/0000-0002-9170-7508","observed_orcids":["https://orcid.org/0000-0002-9170-7508"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yanan Liu","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113961545","display_name":"Yaning Guo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yaning Guo","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rui Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rui Wang","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044267305","display_name":"Yongxue Chen","orcid":"https://orcid.org/0000-0003-0260-2825","observed_orcids":["https://orcid.org/0000-0003-0260-2825"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yongxue Chen","raw_affiliation_strings":["Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Handan Central Hospital Handan 056001, Hebei Province, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8094,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.83322629,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"13","issue":"7","first_page":"8186","last_page":"8192"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.12160000205039978,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/goal-directed-fluid-therapy","display_name":"goal-directed fluid therapy","score":1.0},{"id":"https://openalex.org/keywords/enhanced-recovery-after-surgery","display_name":"enhanced recovery after surgery","score":0.9990000128746033},{"id":"https://openalex.org/keywords/intraoperative-fluid-management","display_name":"intraoperative fluid management","score":0.6990000009536743},{"id":"https://openalex.org/keywords/hemodynamic-stability","display_name":"hemodynamic stability","score":0.8619999885559082},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.9509999752044678},{"id":"https://openalex.org/keywords/postoperative-recovery","display_name":"postoperative recovery","score":0.7459999918937683},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.875},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.6779999732971191},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9169999957084656},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9079999923706055},{"id":"https://openalex.org/keywords/postoperative-quality-of-life","display_name":"postoperative quality of life","score":0.9539999961853027}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7584143877029419},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.5733821392059326},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5460935831069946},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.5020978450775146},{"id":"https://openalex.org/C31861589","wikidata":"https://www.wikidata.org/wiki/Q618068","display_name":"Cardiac index","level":4,"score":0.49688175320625305},{"id":"https://openalex.org/C80461066","wikidata":"https://www.wikidata.org/wiki/Q1698533","display_name":"Stroke volume","level":4,"score":0.4824543595314026},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.4753674864768982},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4385940432548523},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.42764949798583984},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3919208347797394},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.36290109157562256},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19389349222183228}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:34377304","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34377304","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8340232","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8340232/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},{"id":"mag:3193045461","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34377304/","pdf_url":null,"source":{"id":"https://openalex.org/S25983388","display_name":"American Journal of Translational Research","issn_l":"1943-8141","issn":["1943-8141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320994","host_organization_name":"e-Century Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310320994"],"host_organization_lineage_names":["e-Century Publishing Corporation"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Translational Research","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8340232","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8340232/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1607545347","https://openalex.org/W1967290866","https://openalex.org/W1980012545","https://openalex.org/W2114749129","https://openalex.org/W2135313177","https://openalex.org/W2148052094","https://openalex.org/W2413737962","https://openalex.org/W2533368327","https://openalex.org/W2536894257","https://openalex.org/W2748151948","https://openalex.org/W2802777379","https://openalex.org/W2804318759","https://openalex.org/W2888245356","https://openalex.org/W2900862681","https://openalex.org/W2904083202","https://openalex.org/W2954411966","https://openalex.org/W2980085392","https://openalex.org/W3011765510","https://openalex.org/W3027386403","https://openalex.org/W3031079325","https://openalex.org/W3097082087"],"related_works":["https://openalex.org/W3174316990","https://openalex.org/W4383721525","https://openalex.org/W3029139945","https://openalex.org/W7039478253","https://openalex.org/W3187384676","https://openalex.org/W3196670955","https://openalex.org/W3113395216","https://openalex.org/W3207843637","https://openalex.org/W4288385036","https://openalex.org/W2767883297"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"explore":[2],"the":[3,12,37,45,82,150,171,179,195],"application":[4],"value":[5],"of":[6,18,29,157,182,197],"goal-directed":[7,75],"fluid":[8,76,83,93],"therapy":[9],"(GDFT)":[10],"in":[11,44,91],"enhanced":[13],"recovery":[14,39,181],"after":[15,40,112,138,184],"surgery":[16,24,41],"(ERAS)":[17,42],"patients":[19,31,183],"undergoing":[20,32],"radical":[21],"lung":[22],"cancer":[23],"(RLCS).":[25],"METHODS:":[26],"A":[27],"total":[28],"74":[30],"elective":[33],"RLCS":[34],"based":[35],"on":[36,193],"enhance":[38],"concept":[43],"HanDan":[46],"Central":[47],"Hospital":[48],"between":[49],"December":[50,53],"2016":[51],"and":[52,57,70,95,108,127,133,160,163,200,203],"2019":[54],"were":[55,89],"enrolled":[56],"assigned":[58],"to":[59,81,178],"a":[60,71,190],"group":[61,72,152],"treated":[62,73],"by":[63,74],"regular":[64,172],"conventional":[65],"liquids":[66],"(regular":[67],"group,":[68,78],"n=34)":[69],"(GDFT":[77],"n=40)":[79],"according":[80],"infusion":[84],"scheme.":[85],"The":[86],"two":[87],"groups":[88],"compared":[90],"intraoperative":[92],"inflow":[94],"outflow,":[96],"hemodynamic":[97,198],"indexes":[98,199],"at":[99,120,128],"30":[100],"min":[101],"(T0)":[102],"before":[103,125],"operation,":[104,113,126,139],"4":[105],"h":[106,110],"(T1)":[107],"24":[109],"(T2)":[111],"postoperative":[114,116,144,204],"complications,":[115],"recovery,":[117],"inflammatory":[118],"factors":[119],"1":[121,129],"day":[122,130],"(d":[123,131,136],"0)":[124],"1)":[132],"7":[134],"days":[135],"3)":[137],"as":[140,142],"well":[141],"for":[143],"life":[145,167],"quality.":[146],"RESULTS:":[147],"<0.05).":[148],"Moreover,":[149],"GDFT":[151,175],"presented":[153],"with":[154],"less":[155],"fluctuation":[156],"IL-10,":[158],"IL-6,":[159],"TNF-\u03b1":[161],"levels":[162],"experienced":[164],"notably":[165],"higher":[166],"quality":[168],"scores":[169],"than":[170],"group.":[173],"CONCLUSION:":[174],"is":[176],"beneficial":[177],"rapid":[180],"RLCS,":[185],"because":[186],"it":[187],"can":[188],"exert":[189],"positive":[191],"effect":[192],"maintaining":[194],"stability":[196],"reducing":[201],"inflammation":[202],"complications.":[205]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-08-16T00:00:00"}