{"id":"https://openalex.org/W3190768942","doi":"https://doi.org/10.3389/fmicb.2021.707332","title":"Genetic Features of Plasmid- and Chromosome-Mediated mcr-1 in Escherichia coli Isolates From Animal Organs With Lesions","display_name":"Genetic Features of Plasmid- and Chromosome-Mediated mcr-1 in Escherichia coli Isolates From Animal Organs With Lesions","publication_year":2021,"publication_date":"2021-08-05","ids":{"openalex":"https://openalex.org/W3190768942","doi":"https://doi.org/10.3389/fmicb.2021.707332","mag":"3190768942","pmid":"https://pubmed.ncbi.nlm.nih.gov/34456890","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8386294"},"language":"en","primary_location":{"id":"doi:10.3389/fmicb.2021.707332","doi":"https://doi.org/10.3389/fmicb.2021.707332","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmicb.2021.707332","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmicb.2021.707332/pdf","source":{"id":"https://openalex.org/S2484704948","display_name":"Frontiers in Microbiology","issn_l":"1664-302X","issn":["1664-302X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fmicb.2021.707332/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013078483","display_name":"Zengyuan Liu","orcid":"https://orcid.org/0000-0001-9132-5449","observed_orcids":["https://orcid.org/0000-0001-9132-5449","https://orcid.org/0009-0004-9097-2643"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zengyuan Liu","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078591427","display_name":"Yingqiu Liu","orcid":"https://orcid.org/0000-0001-5272-1377","observed_orcids":["https://orcid.org/0000-0001-5272-1377"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingqiu Liu","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Xi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei Xi","raw_affiliation_strings":["Qingdao Adverse Drug Reaction Monitoring Center, China Qingdao Institute for Food and Drug Control, Qingdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qingdao Adverse Drug Reaction Monitoring Center, China Qingdao Institute for Food and Drug Control, Qingdao, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005667027","display_name":"Shuangshi Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuangshi Liu","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100409762","display_name":"Jia Liu","orcid":"https://orcid.org/0000-0003-3612-6089","observed_orcids":["https://orcid.org/0000-0003-3612-6089"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Liu","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112859612","display_name":"Hailong Mu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hailong Mu","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100714562","display_name":"Beibei Chen","orcid":"https://orcid.org/0000-0001-7772-5171","observed_orcids":["https://orcid.org/0000-0001-7772-5171","https://orcid.org/0009-0000-1019-0299"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Beibei Chen","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075095997","display_name":"Hao He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao He","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101848493","display_name":"Yunpeng Fan","orcid":"https://orcid.org/0000-0002-6899-4203","observed_orcids":["https://orcid.org/0000-0002-6899-4203"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunpeng Fan","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102377371","display_name":"Wuren Ma","orcid":"https://orcid.org/0000-0001-7846-0056","observed_orcids":["https://orcid.org/0000-0001-7846-0056"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wuren Ma","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100340718","display_name":"Weimin Zhang","orcid":"https://orcid.org/0000-0001-8945-9448","observed_orcids":["https://orcid.org/0000-0001-8945-9448"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weimin Zhang","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031554624","display_name":"Mingzhe Fu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingzhe Fu","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100347436","display_name":"Juan Wang","orcid":"https://orcid.org/0000-0002-3176-173X","observed_orcids":["https://orcid.org/0000-0002-3176-173X","https://orcid.org/0000-0003-1678-1211"]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Juan Wang","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110006607","display_name":"Xiaoping Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoping Song","raw_affiliation_strings":["College of Veterinary Medicine, Northwest A&F University, Yangling, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Veterinary Medicine, Northwest A&F University, Yangling, China","institution_ids":["https://openalex.org/I89652312"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100347436","https://openalex.org/A5110006607"],"corresponding_institution_ids":["https://openalex.org/I89652312"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":1.5481,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.782875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":null,"first_page":"707332","last_page":"707332"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mcr-1","display_name":"mcr-1","score":0.9390000104904175},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.890999972820282},{"id":"https://openalex.org/keywords/plasmid-mediated-antimicrobial-resistance","display_name":"plasmid-mediated antibiotic resistance","score":0.7760000228881836},{"id":"https://openalex.org/keywords/incx3-plasmid","display_name":"IncX3 plasmid","score":0.7329999804496765},{"id":"https://openalex.org/keywords/type-iv-secretion-system","display_name":"type IV secretion system","score":0.765999972820282},{"id":"https://openalex.org/keywords/trai","display_name":"TraI","score":0.9559999704360962},{"id":"https://openalex.org/keywords/class-1-integron","display_name":"class 1 integron","score":0.7919999957084656},{"id":"https://openalex.org/keywords/composite-transposon","display_name":"composite transposon","score":0.9959999918937683},{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.765999972820282},{"id":"https://openalex.org/keywords/extensive-drug-resistance","display_name":"extensive drug resistance","score":0.6150000095367432},{"id":"https://openalex.org/keywords/pigs","display_name":"pigs","score":0.6380000114440918},{"id":"https://openalex.org/keywords/plasmid-conjugation","display_name":"plasmid conjugation","score":0.8069999814033508},{"id":"https://openalex.org/keywords/population-structure","display_name":"population structure","score":0.32600000500679016}],"concepts":[{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.8884806632995605},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.8874281048774719},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8346343040466309},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5227560997009277},{"id":"https://openalex.org/C10147152","wikidata":"https://www.wikidata.org/wiki/Q5413339","display_name":"Gene cassette","level":5,"score":0.5214961767196655},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5194641947746277},{"id":"https://openalex.org/C157887575","wikidata":"https://www.wikidata.org/wiki/Q417216","display_name":"Insertion sequence","level":5,"score":0.4940353035926819},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4935492277145386},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.48084601759910583},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.47706830501556396},{"id":"https://openalex.org/C4918238","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"Transposable element","level":4,"score":0.47638171911239624},{"id":"https://openalex.org/C77434933","wikidata":"https://www.wikidata.org/wiki/Q4043440","display_name":"Multilocus sequence typing","level":4,"score":0.4482913613319397},{"id":"https://openalex.org/C2776650774","wikidata":"https://www.wikidata.org/wiki/Q420197","display_name":"Integron","level":4,"score":0.4065471887588501},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2577438950538635},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.2101576328277588},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.13706287741661072},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fmicb.2021.707332","doi":"https://doi.org/10.3389/fmicb.2021.707332","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmicb.2021.707332","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmicb.2021.707332/pdf","source":{"id":"https://openalex.org/S2484704948","display_name":"Frontiers in Microbiology","issn_l":"1664-302X","issn":["1664-302X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Microbiology","raw_type":"journal-article"},{"id":"pmid:34456890","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34456890","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8386294","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8386294/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Microbiol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:ecfe1e941cfc46e9969605ee62f8623a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ecfe1e941cfc46e9969605ee62f8623a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Microbiology, Vol 12 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fmicb.2021.707332","doi":"https://doi.org/10.3389/fmicb.2021.707332","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmicb.2021.707332","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmicb.2021.707332/pdf","source":{"id":"https://openalex.org/S2484704948","display_name":"Frontiers in Microbiology","issn_l":"1664-302X","issn":["1664-302X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5626088553","display_name":null,"funder_award_id":"31802230","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320336567","display_name":"Natural Science Basic Research Program of Shaanxi Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3190768942.pdf","grobid_xml":"https://content.openalex.org/works/W3190768942.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W2044174279","https://openalex.org/W2055634464","https://openalex.org/W2091030812","https://openalex.org/W2114853012","https://openalex.org/W2116245384","https://openalex.org/W2142343447","https://openalex.org/W2179036997","https://openalex.org/W2227999376","https://openalex.org/W2229353552","https://openalex.org/W2345428819","https://openalex.org/W2346391671","https://openalex.org/W2398111137","https://openalex.org/W2419484789","https://openalex.org/W2461087574","https://openalex.org/W2507426465","https://openalex.org/W2513186500","https://openalex.org/W2518717259","https://openalex.org/W2524156053","https://openalex.org/W2526116747","https://openalex.org/W2539523900","https://openalex.org/W2563854390","https://openalex.org/W2565234447","https://openalex.org/W2582776852","https://openalex.org/W2593444269","https://openalex.org/W2734199024","https://openalex.org/W2736380266","https://openalex.org/W2747942801","https://openalex.org/W2763294214","https://openalex.org/W2768017947","https://openalex.org/W2770787983","https://openalex.org/W2770937934","https://openalex.org/W2897109701","https://openalex.org/W2902708397","https://openalex.org/W2904736766","https://openalex.org/W2940449731","https://openalex.org/W2949907272","https://openalex.org/W2952167528","https://openalex.org/W2964107478","https://openalex.org/W2972993315","https://openalex.org/W2999108748","https://openalex.org/W3000707168","https://openalex.org/W3005357307","https://openalex.org/W3006255328","https://openalex.org/W3033371523","https://openalex.org/W3048549725","https://openalex.org/W3048693617","https://openalex.org/W3142434525"],"related_works":["https://openalex.org/W2524156053","https://openalex.org/W4324375418","https://openalex.org/W4387176730","https://openalex.org/W2751991523","https://openalex.org/W4392166981","https://openalex.org/W4409405116","https://openalex.org/W2531763872","https://openalex.org/W2794207420","https://openalex.org/W2902961292","https://openalex.org/W7164587292"],"abstract_inverted_index":{"The":[0,39,62,144,166,193,236],"genomic":[1],"context":[2],"of":[3,30,51,164,171,197,248,264,277],"the":[4,22,43,87,113,118,125,131,150,161,186,189,241,246,253,261,269,273],"mcr-1":[5,114,132,145],"gene":[6,115,133,146,170,238],"in":[7,106,136,154,221,260],"Escherichia":[8,31,53,70,218],"coli":[9,32,54,71,219],"from":[10,34,57],"animal":[11,35,58],"feces":[12],"has":[13],"been":[14],"widely":[15],"reported.":[16],"However,":[17],"less":[18],"is":[19,147],"known":[20],"about":[21],"mcr-1-carrying":[23],"plasmid":[24,163,249,266,271],"characteristics":[25],"and":[26,48,96,127,152,168,181,183,188,207,232,257,275],"other":[27],"functional":[28],"regions":[29],"isolates":[33,72,220],"organs":[36,59],"with":[37,60],"lesions.":[38,61],"present":[40],"study":[41,223],"investigated":[42],"antimicrobial":[44,63,81,278],"resistance,":[45],"population":[46,234],"structure,":[47],"genetic":[49],"features":[50],"mcr-1-positive":[52,69,217],"strains":[55],"isolated":[56],"susceptibility":[64],"testing":[65],"indicated":[66,130],"that":[67,86],"24":[68,216],"were":[73,92,177],"resistant":[74,230],"to":[75,109,124,268],"at":[76],"least":[77],"three":[78],"or":[79,226],"all":[80],"categories.":[82],"MLST":[83],"analysis":[84],"suggested":[85],"dominant":[88],"clone":[89],"complexes":[90],"(CC)":[91],"mainly":[93],"CC156,":[94],"CC448,":[95],"CC10.":[97],"In":[98],"addition,":[99],"ST10596,":[100],"a":[101],"newly":[102],"discovered":[103],"sequence":[104,243],"type":[105,172],"swine,":[107],"failed":[108],"be":[110],"classified.":[111],"Meanwhile,":[112],"located":[116,148,184],"on":[117,149,160,185],"different":[119],"plasmids":[120,199],"was":[121,134,158],"successfully":[122],"transferred":[123],"recipients,":[126],"whole-genome":[128],"sequencing":[129],"embedded":[135,153],"mcr-1-pap2":[137],"cassette":[138],"but":[139],"not":[140],"flanked":[141],"by":[142,179,240],"ISApl1.":[143],"chromosome":[151],"Tn6330.":[155],"Furthermore,":[156,252],"NDM-5":[157],"found":[159],"IncX3-type":[162],"J-8.":[165],"virB6":[167],"traI":[169],"IV":[173],"secretion":[174],"system":[175],"(T4SS)":[176],"truncated":[178],"IS2":[180],"IS100":[182],"IncX4-":[187],"IncHI2/HI2A/N-type":[190,198],"plasmids,":[191],"respectively.":[192],"multidrug-resistant":[194],"(MDR)":[195],"region":[196,263],"contained":[200],"two":[201],"class":[202,254],"1":[203,255],"integrons":[204,256],"(In0,":[205],"In640)":[206],"four":[208],"composite":[209,258],"transposons":[210,259],"(Tn4352,":[211],"Tn6010,":[212],"cn_4692_IS26,":[213],"cn_6354_IS26).":[214],"Overall,":[215],"our":[222],"showed":[224],"MDR,":[225],"even":[227],"extensively":[228],"drug":[229],"(XDR),":[231],"exhibited":[233],"diversity.":[235],"T4SS":[237],"truncation":[239],"insertion":[242],"may":[244],"affect":[245],"efficiency":[247],"conjugative":[250],"transfer.":[251],"MDR":[262],"IncHI2/HI2A/n-type":[265],"contributed":[267],"multireplicon":[270],"formation,":[272],"acquisition,":[274],"transfer":[276],"resistance":[279],"genes":[280],"(ARGs).":[281]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-08-16T00:00:00"}