{"id":"https://openalex.org/W3189246713","doi":null,"title":"Anticancer, Cytotoxicity and Antimicrobial of Zinc Oxide Nanoparticles","display_name":"Anticancer, Cytotoxicity and Antimicrobial of Zinc Oxide Nanoparticles","publication_year":2021,"publication_date":"2021-04-07","ids":{"openalex":"https://openalex.org/W3189246713","mag":"3189246713"},"language":"en","primary_location":{"id":"mag:3189246713","doi":null,"is_oa":false,"landing_page_url":"http://annalsofrscb.ro/index.php/journal/article/view/2518","pdf_url":null,"source":{"id":"https://openalex.org/S4306502306","display_name":"Annals of the Romanian Society for Cell Biology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Annals of the Romanian Society for Cell Biology","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073678317","display_name":"Thaer Ali Hussein","orcid":"https://orcid.org/0000-0003-0920-1557","observed_orcids":["https://orcid.org/0000-0003-0920-1557"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thaer Ali Hussein","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0920-1557","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035820982","display_name":"Mohammed Hassan Flaih","orcid":"https://orcid.org/0000-0001-9824-6778","observed_orcids":["https://orcid.org/0000-0001-9824-6778"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammed Hassan Flaih","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9824-6778","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5037555165","display_name":"Munther Kamil Oudah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Munther Kamil Oudah","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"901","last_page":"909"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10090","display_name":"ZnO doping and properties","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13104","display_name":"Chemical and Physical Properties of Materials","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zinc-oxide-nanoparticles","display_name":"zinc oxide nanoparticles","score":1.0},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9390000104904175},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8690000176429749},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7910000085830688},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.968999981880188},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":1.0},{"id":"https://openalex.org/keywords/minimum-inhibitory-concentration","display_name":"minimum inhibitory concentration","score":0.9829999804496765},{"id":"https://openalex.org/keywords/minimum-bactericidal-concentration","display_name":"minimum bactericidal concentration","score":0.9570000171661377},{"id":"https://openalex.org/keywords/chemical-synthesis-of-nanoparticles","display_name":"chemical synthesis of nanoparticles","score":0.6949999928474426}],"concepts":[{"id":"https://openalex.org/C176947019","wikidata":"https://www.wikidata.org/wiki/Q597889","display_name":"Minimum inhibitory concentration","level":3,"score":0.7394894361495972},{"id":"https://openalex.org/C535196362","wikidata":"https://www.wikidata.org/wiki/Q758","display_name":"Zinc","level":2,"score":0.7120198607444763},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.6630745530128479},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.6582685708999634},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.6497201323509216},{"id":"https://openalex.org/C26381139","wikidata":"https://www.wikidata.org/wiki/Q1158816","display_name":"Minimum bactericidal concentration","level":4,"score":0.6171694993972778},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.590874433517456},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.5727369785308838},{"id":"https://openalex.org/C138631740","wikidata":"https://www.wikidata.org/wiki/Q967847","display_name":"Nanomaterials","level":2,"score":0.5664145946502686},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5557422637939453},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.5512698888778687},{"id":"https://openalex.org/C11636898","wikidata":"https://www.wikidata.org/wiki/Q390585","display_name":"Agar diffusion test","level":4,"score":0.5024805068969727},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4863177239894867},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.480608195066452},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4596533179283142},{"id":"https://openalex.org/C146088050","wikidata":"https://www.wikidata.org/wiki/Q744818","display_name":"Transmission electron microscopy","level":2,"score":0.4391595721244812},{"id":"https://openalex.org/C2776051709","wikidata":"https://www.wikidata.org/wiki/Q632006","display_name":"Gram-negative bacteria","level":4,"score":0.4343823492527008},{"id":"https://openalex.org/C2778660310","wikidata":"https://www.wikidata.org/wiki/Q177998","display_name":"Agar","level":3,"score":0.42301619052886963},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3834347724914551},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.37712278962135315},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3235316276550293},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13337719440460205},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12729057669639587},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07460403442382812},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3189246713","doi":null,"is_oa":false,"landing_page_url":"http://annalsofrscb.ro/index.php/journal/article/view/2518","pdf_url":null,"source":{"id":"https://openalex.org/S4306502306","display_name":"Annals of the Romanian Society for Cell Biology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Annals of the Romanian Society for Cell Biology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2099040357","https://openalex.org/W2136381847","https://openalex.org/W4281725499","https://openalex.org/W2943048766","https://openalex.org/W4411909666","https://openalex.org/W7220532055","https://openalex.org/W2991750861","https://openalex.org/W4323567565","https://openalex.org/W2530851489","https://openalex.org/W4409437898"],"abstract_inverted_index":{"Zinc":[0],"oxide":[1,8],"nanoparticles":[2,9],"(ZnO-NPs)":[3],"are":[4],"versatile":[5],"inorganic":[6],"metal":[7],"known":[10],"widely,":[11],"which":[12],"use":[13],"in":[14],"a":[15,86,118,141,238],"broad":[16],"spectrum":[17],"of":[18,34,49,80,124,134,159,164,169,178,228,233],"the":[19,35,50,62,78,125,167,184,241],"applications.":[20],"In":[21,60],"this":[22],"study,":[23],"chemical":[24],"method":[25],"was":[26,94,128,224,235,243],"used":[27,66],"to":[28,182,197],"prepare":[29],"ZnO-NPs.The":[30],"shape":[31],"and":[32,47,56,103,111,152,191,200,206,240],"size":[33],"prepared":[36,51,63,92,126],"nanomaterial":[37],"were":[38,53,65,115,180],"visualizedbya":[39],"transmission":[40],"electron":[41],"microscope":[42],"(TEM).":[43],"The":[44,91,121,193,210,230],"average":[45],"length":[46],"diameter":[48],"ZnO-NPs":[52,64,84,93,127,135,179],"approximately100-200":[54],"nm":[55],"25-50":[57],"nm,":[58],"respectively.":[59,209],"vitro,":[61],"as":[67,97,117,140,216],"an":[68,98,157],"anticancer":[69],"agent":[70,100],"toward":[71],"breast":[72],"cancer":[73],"cell":[74],"lines":[75],"(MCF-7).":[76],"However,":[77],"results":[79],"MTT":[81],"assay":[82],"showedthat":[83],"is":[85],"promising":[87],"drug":[88],"against":[89,101,212],"MCF-7.":[90],"also":[95,129],"tested":[96,181],"antimicrobial":[99],"(gramnegative":[102],"gram":[104,219],"positive)":[105],"bacteria.":[106,221],"Escherichia":[107],"coli":[108,205],"(E.":[109],"coli)":[110],"Staphylococcus":[112],"aureus":[113],"(S.aureus)":[114],"selected":[116],"test":[119],"ofbacteria.":[120],"antibacterial":[122,226,231],"profile":[123],"studied":[130],"with":[131,136,161,218],"different":[132,137,162,176],"concentration":[133,150,155,223],"methods":[138],"such":[139],"disc":[142],"method,":[143,147],"well":[144],"diffusion":[145],"agar":[146],"minimum":[148,153],"bactericidal":[149],"(MBC)":[151],"inhibitory":[154],"(MIC).Moreover,":[156],"effect":[158,232,242],"time":[160,239],"concentrations":[163,177],"Zn-ONPs":[165],"at":[166],"growth":[168],"S.":[170,207],"aureusand":[171],"E.":[172,204],"coliwas":[173],"studied.":[174],"Five":[175],"determine":[183],"MICthatincludes":[185],"15,":[186],"10,":[187],"5,":[188],"2.5,":[189],"1,":[190],"0.5mg/ml.":[192],"MIC":[194],"valueswere":[195],"found":[196],"be":[198],"1":[199],"0.5":[201],"g/m":[202],"for":[203],"aureus,":[208],"resistivity":[211],"gram-positive":[213],"bacteria":[214],"wasless":[215],"compared":[217],"negative":[220],"IncreasingZnO-NPs":[222],"relatedwithhigh":[225],"activity":[227],"ZnO-NPs.":[229],"ZnONPs":[234],"depending":[236],"on":[237],"gradually.":[244]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2021-08-16T00:00:00"}