{"id":"https://openalex.org/W3189079727","doi":"https://doi.org/10.1056/nejmoa2028973","title":"Variant PNLDC1 , Defective piRNA Processing, and Azoospermia","display_name":"Variant PNLDC1 , Defective piRNA Processing, and Azoospermia","publication_year":2021,"publication_date":"2021-08-04","ids":{"openalex":"https://openalex.org/W3189079727","doi":"https://doi.org/10.1056/nejmoa2028973","mag":"3189079727","pmid":"https://pubmed.ncbi.nlm.nih.gov/34347949","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7615015"},"language":"en","primary_location":{"id":"doi:10.1056/nejmoa2028973","doi":"https://doi.org/10.1056/nejmoa2028973","is_oa":true,"landing_page_url":"https://doi.org/10.1056/nejmoa2028973","pdf_url":"https://www.nejm.org/doi/pdf/10.1056/NEJMoa2028973?articleTools=true","source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.nejm.org/doi/pdf/10.1056/NEJMoa2028973?articleTools=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027622786","display_name":"Liina Nagirnaja","orcid":"https://orcid.org/0000-0003-1948-2495","observed_orcids":["https://orcid.org/0000-0003-1948-2495"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Liina Nagirnaja","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Rigshospitalet"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Rigshospitalet","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090097089","display_name":"Nina M\u00f8rup","orcid":"https://orcid.org/0000-0002-7332-4116","observed_orcids":["https://orcid.org/0000-0002-7332-4116"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Nina M\u00f8rup","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Growth and Reproduction, Rigshospitalet","International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet"],"raw_orcid":"https://orcid.org/0000-0002-7332-4116","affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":null,"display_name":"John E. Nielsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"John E. Nielsen","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Growth and Reproduction, Rigshospitalet","International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020232912","display_name":"Rytis Stakaitis","orcid":"https://orcid.org/0000-0001-5946-1731","observed_orcids":["https://orcid.org/0000-0001-5946-1731"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I4210113153","display_name":"Neuroscience Institute","ror":"https://ror.org/0240rwx68","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210113153","https://openalex.org/I4210155236"]}],"countries":["DK","IT","LT","US"],"is_corresponding":false,"raw_author_name":"Rytis Stakaitis","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Growth and Reproduction, Rigshospitalet","International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","Laboratory of Molecular Neurooncology, Neuroscience Institute"],"raw_orcid":"https://orcid.org/0000-0001-5946-1731","affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"Laboratory of Molecular Neurooncology, Neuroscience Institute","institution_ids":["https://openalex.org/I4210113153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112953406","display_name":"Ieva Golubickait\u0117","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Ieva Golubickaite","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Growth and Reproduction, Rigshospitalet","Institute of Biology Systems and Genetic Research, Lithuanian University of Health Sciences, Kaunas, Lithuania","International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet"],"raw_orcid":"https://orcid.org/0000-0003-2739-8576","affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"Institute of Biology Systems and Genetic Research, Lithuanian University of Health Sciences, Kaunas, Lithuania","institution_ids":["https://openalex.org/I131736796"]},{"raw_affiliation_string":"International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079740224","display_name":"Manon S. Oud","orcid":"https://orcid.org/0000-0001-9513-3030","observed_orcids":["https://orcid.org/0000-0001-9513-3030"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["DK","LT","NL","US"],"is_corresponding":false,"raw_author_name":"Manon S. Oud","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior","institution_ids":["https://openalex.org/I4405261313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079833628","display_name":"Sofia Boeg Winge","orcid":"https://orcid.org/0000-0003-1666-1228","observed_orcids":["https://orcid.org/0000-0003-1666-1228"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Sofia B. Winge","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Growth and Reproduction, Rigshospitalet"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081167690","display_name":"Filipa Carvalho","orcid":"https://orcid.org/0000-0001-9546-4614","observed_orcids":["https://orcid.org/0000-0001-9546-4614"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802934949"]}],"countries":["DK","LT","NL","PT","US"],"is_corresponding":false,"raw_author_name":"Filipa Carvalho","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands","Servi\u00e7o de Gen\u00e9tica, Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Servi\u00e7o de Gen\u00e9tica, Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I182534213","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057668804","display_name":"Kenneth Ivan Aston","orcid":"https://orcid.org/0000-0001-6459-2103","observed_orcids":["https://orcid.org/0000-0001-6459-2103"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Kenneth I. Aston","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","University of Utah School of Medicine, Salt Lake City"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"University of Utah School of Medicine, Salt Lake City","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059654230","display_name":"Francesca Khani","orcid":"https://orcid.org/0000-0001-7238-8604","observed_orcids":["https://orcid.org/0000-0001-7238-8604"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Francesca Khani","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Departments of Pathology and Laboratory Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Departments of Pathology and Laboratory Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017573071","display_name":"Godfried W. van der Heijden","orcid":"https://orcid.org/0000-0001-5894-7027","observed_orcids":["https://orcid.org/0000-0001-5894-7027"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["DK","LT","NL","US"],"is_corresponding":false,"raw_author_name":"Godfried W. van der Heijden","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior","Department of Obstetrics and Gynecology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior","institution_ids":["https://openalex.org/I4405261313"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054681026","display_name":"Cristina Joana Marques","orcid":"https://orcid.org/0000-0002-5658-3773","observed_orcids":["https://orcid.org/0000-0002-5658-3773"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802934949"]}],"countries":["DK","LT","NL","PT","US"],"is_corresponding":false,"raw_author_name":"C. Joana Marques","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands","Servi\u00e7o de Gen\u00e9tica, Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Servi\u00e7o de Gen\u00e9tica, Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I182534213","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081123168","display_name":"Niels  Erik Skakkeb\u00e6k","orcid":"https://orcid.org/0000-0002-4282-8020","observed_orcids":["https://orcid.org/0000-0002-4282-8020"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Niels E. Skakkebaek","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Growth and Reproduction, Rigshospitalet","International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071655240","display_name":"Ewa Rajpert\u2010De Meyts","orcid":"https://orcid.org/0000-0002-5946-7559","observed_orcids":["https://orcid.org/0000-0002-5946-7559"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Ewa Rajpert\u2013De Meyts","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073428580","display_name":"Peter N. Schlegel","orcid":"https://orcid.org/0000-0002-7129-8137","observed_orcids":["https://orcid.org/0000-0002-7129-8137"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Peter N. Schlegel","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Urology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Urology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069431123","display_name":"Niklas Rye J\u00f8rgensen","orcid":"https://orcid.org/0000-0001-9624-5210","observed_orcids":["https://orcid.org/0000-0001-9624-5210"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Niels J\u00f8rgensen","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Growth and Reproduction, Rigshospitalet","International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024404524","display_name":"Joris A. Veltman","orcid":"https://orcid.org/0000-0002-3218-8250","observed_orcids":["https://orcid.org/0000-0002-3218-8250"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["DK","GB","LT","US"],"is_corresponding":false,"raw_author_name":"Joris A. Veltman","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016955998","display_name":"Alexandra Manuel Lopes","orcid":"https://orcid.org/0000-0003-3539-2318","observed_orcids":["https://orcid.org/0000-0003-3539-2318"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802934949"]}],"countries":["DK","LT","NL","PT","US"],"is_corresponding":false,"raw_author_name":"Alexandra M. Lopes","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Institute of Molecular Pathology and Immunology of the University of Porto, Radboud University Medical Center, Nijmegen, the Netherlands","Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Institute of Molecular Pathology and Immunology of the University of Porto, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto, Radboud University Medical Center, Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050987953","display_name":"Donald F. Conrad","orcid":"https://orcid.org/0000-0003-3828-8970","observed_orcids":["https://orcid.org/0000-0003-3828-8970"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["DK","LT","US"],"is_corresponding":false,"raw_author_name":"Donald F. Conrad","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, Rigshospitalet","Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Rigshospitalet"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, Rigshospitalet","institution_ids":["https://openalex.org/I165690674"]},{"raw_affiliation_string":"Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Rigshospitalet","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I165690674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024546908","display_name":"Kristian Almstrup","orcid":"https://orcid.org/0000-0002-1832-0307","observed_orcids":["https://orcid.org/0000-0002-1832-0307"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]},{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK","LT","US"],"is_corresponding":true,"raw_author_name":"Kristian Almstrup","raw_affiliation_strings":["From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen","Department of Growth and Reproduction, Rigshospitalet","International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet"],"raw_orcid":"https://orcid.org/0000-0002-1832-0307","affiliations":[{"raw_affiliation_string":"From the Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton (L.N., D.F.C.); the Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland (D.F.C.); the Department of Growth and Reproduction (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.) and the International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (N.M., J.E.N., R.S., I.G., S.B.W., N.E.S., E.R.-D.M., N.J., K.A.), Rigshospitalet, and the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences (K.A.), University of Copenhagen, Copenhagen; the Laboratory of Molecular Neurooncology, Neuroscience Institute (R.S.), and the Institute of Biology Systems and Genetic Research (I.G.), Lithuanian University of Health Sciences, Kaunas, Lithuania; the Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior (M.S.O., G.W.H","institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Department of Growth and Reproduction, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health, Rigshospitalet","institution_ids":["https://openalex.org/I2802709434"]}]}],"institutions":[],"countries_distinct_count":7,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5024546908"],"corresponding_institution_ids":["https://openalex.org/I102507086","https://openalex.org/I124055696","https://openalex.org/I131736796","https://openalex.org/I165690674","https://openalex.org/I2802709434"],"apc_list":null,"apc_paid":null,"fwci":12.7447,"has_fulltext":true,"cited_by_count":113,"citation_normalized_percentile":{"value":0.99626042,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":100},"biblio":{"volume":"385","issue":"8","first_page":"707","last_page":"719"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/azoospermia","display_name":"azoospermia","score":0.8569999933242798},{"id":"https://openalex.org/keywords/male-infertility","display_name":"male infertility","score":0.8069999814033508},{"id":"https://openalex.org/keywords/non-obstructive-azoospermia","display_name":"non-obstructive azoospermia","score":0.9279999732971191},{"id":"https://openalex.org/keywords/piwi-interacting-rnas","display_name":"piRNA","score":0.8479999899864197},{"id":"https://openalex.org/keywords/meiosis","display_name":"meiosis","score":0.6620000004768372},{"id":"https://openalex.org/keywords/spermatogenesis","display_name":"spermatogenesis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/germ-cells","display_name":"germ cells","score":0.6600000262260437},{"id":"https://openalex.org/keywords/transposable-elements","display_name":"transposable elements","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C2777420699","wikidata":"https://www.wikidata.org/wiki/Q794026","display_name":"Azoospermia","level":4,"score":0.6312642693519592},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36123889684677124},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3471611738204956},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.252052903175354},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.15203309059143066},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005095","descriptor_name":"Exoribonucleases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007248","descriptor_name":"Infertility, Male","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008540","descriptor_name":"Meiosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D053713","descriptor_name":"Azoospermia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D053713","descriptor_name":"Azoospermia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1056/nejmoa2028973","doi":"https://doi.org/10.1056/nejmoa2028973","is_oa":true,"landing_page_url":"https://doi.org/10.1056/nejmoa2028973","pdf_url":"https://www.nejm.org/doi/pdf/10.1056/NEJMoa2028973?articleTools=true","source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:34347949","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34347949","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New England journal of medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire/c8f05c1d-42fe-45fd-a744-d246a57c088f","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/c8f05c1d-42fe-45fd-a744-d246a57c088f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nagirnaja, L, M\u00f8rup, N, Nielsen, J E, Stakaitis, R, Golubickaite, I, Oud, M S, Winge, S B, Carvalho, F, Aston, K I, Khani, F, Van Der Heijden, G W, Marques, C J, Skakkebaek, N E, Rajpert\u2013de Meyts, E, Schlegel, P N, J\u00f8rgensen, N, Veltman, J A, Lopes, A M, Conrad, D F & Almstrup, K 2021, 'Variant PNLDC1, Defective piRNA Processing, and Azoospermia', New England Journal of Medicine, vol. 385, no. 8, pp. 707-719. https://doi.org/10.1056/NEJMoa2028973","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7615015","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7615015/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"N Engl J Med","raw_type":"Text"},{"id":"pmh:oai:lsmu.lt:20.500.12512/111658","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34347949/","pdf_url":null,"source":{"id":"https://openalex.org/S7407055191","display_name":"Lithuanian University of Health Sciences","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"research article"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/237917","doi":null,"is_oa":false,"landing_page_url":"https://repository.ubn.ru.nl/handle/2066/237917","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/237917","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/237917","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The New England Journal of Medicine, 385, 707 - 719","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1056/nejmoa2028973","doi":"https://doi.org/10.1056/nejmoa2028973","is_oa":true,"landing_page_url":"https://doi.org/10.1056/nejmoa2028973","pdf_url":"https://www.nejm.org/doi/pdf/10.1056/NEJMoa2028973?articleTools=true","source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2170608084","display_name":null,"funder_award_id":"IF/01262/2014","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G2811956865","display_name":null,"funder_award_id":"918 15 667","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G3267038833","display_name":null,"funder_award_id":"918-15-667","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3724057398","display_name":null,"funder_award_id":"209451","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5592223740","display_name":null,"funder_award_id":"918-15-667","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G6520830658","display_name":null,"funder_award_id":"14\u20102013\u20104","funder_id":"https://openalex.org/F4320313796","funder_display_name":"Innovationsfonden"},{"id":"https://openalex.org/G8614742411","display_name":"Unraveling genetic causes and risk factors for severe male infertility","funder_award_id":"209451/Z/17/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G9000857427","display_name":"Genomics of spermatogenic impairment","funder_award_id":"R01HD078641","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G9000895243","display_name":"Genetics of Male Infertility: Accelerating the pace of discovery","funder_award_id":"P50HD096723","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320313796","display_name":"Innovationsfonden","ror":"https://ror.org/00daj4111"},{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320336587","display_name":"ReproUnion","ror":null},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3189079727.pdf","grobid_xml":"https://content.openalex.org/works/W3189079727.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1977733607","https://openalex.org/W2005568203","https://openalex.org/W2012034410","https://openalex.org/W2051978340","https://openalex.org/W2062288798","https://openalex.org/W2083709197","https://openalex.org/W2092791039","https://openalex.org/W2119180969","https://openalex.org/W2125812119","https://openalex.org/W2146339022","https://openalex.org/W2146883069","https://openalex.org/W2190800365","https://openalex.org/W2416040573","https://openalex.org/W2418321949","https://openalex.org/W2507906552","https://openalex.org/W2538358032","https://openalex.org/W2617924639","https://openalex.org/W2668553901","https://openalex.org/W2736831818","https://openalex.org/W2747335279","https://openalex.org/W2761221289","https://openalex.org/W2761424079","https://openalex.org/W2764264432","https://openalex.org/W2766880616","https://openalex.org/W2786787605","https://openalex.org/W2790182576","https://openalex.org/W2889446142","https://openalex.org/W2905723556","https://openalex.org/W2949356467","https://openalex.org/W2951162972","https://openalex.org/W2953099340","https://openalex.org/W2995253087","https://openalex.org/W2995845102","https://openalex.org/W3000454340","https://openalex.org/W3037082378","https://openalex.org/W3113149486","https://openalex.org/W4254230981"],"related_works":["https://openalex.org/W4413499071","https://openalex.org/W4390114949","https://openalex.org/W4408732040","https://openalex.org/W4378905263","https://openalex.org/W4407642337","https://openalex.org/W7206647990","https://openalex.org/W4224981314","https://openalex.org/W2764264432","https://openalex.org/W2786787605","https://openalex.org/W4402742283"],"abstract_inverted_index":{"BACKGROUND:":[0],"P-element-induced":[1],"wimpy":[2],"testis":[3],"(PIWI)-interacting":[4],"RNAs":[5],"(piRNAs)":[6],"are":[7,18],"short":[8],"(21":[9],"to":[10,38,127],"35":[11],"nucleotides":[12],"in":[13,22,60,97,123],"length)":[14],"and":[15,17,33,64,94,102,121,135],"noncoding":[16],"found":[19],"almost":[20],"exclusively":[21],"germ":[23],"cells,":[24],"where":[25],"they":[26],"regulate":[27],"aberrant":[28],"expression":[29],"of":[30,41,83,92,115],"transposable":[31],"elements":[32],"postmeiotic":[34],"gene":[35],"expression.":[36],"Critical":[37],"the":[39,44],"processing":[40,118],"piRNAs":[42],"is":[43],"protein":[45],"poly(A)-specific":[46],"RNase-like":[47],"domain":[48],"containing":[49],"1":[50],"(PNLDC1),":[51],"which":[52],"trims":[53],"their":[54],"3'":[55],"ends":[56],"and,":[57],"when":[58],"disrupted":[59],"mice,":[61],"causes":[62],"azoospermia":[63],"male":[65,128],"infertility.":[66,129],"METHODS:":[67],"We":[68],"performed":[69],"exome":[70],"sequencing":[71],"on":[72,119],"DNA":[73],"samples":[74,87],"from":[75],"924":[76],"men":[77],"who":[78],"had":[79],"received":[80],"a":[81,111],"diagnosis":[82],"nonobstructive":[84],"azoospermia.":[85],"Testicular-biopsy":[86],"were":[88],"analyzed":[89],"by":[90,131],"means":[91],"histologic":[93],"immunohistochemical":[95],"tests,":[96],"situ":[98],"hybridization,":[99],"reverse-transcriptase-quantitative-polymerase-chain-reaction":[100],"assay,":[101],"small-RNA":[103],"sequencing.":[104],"RESULTS:":[105],"mutations.":[106],"CONCLUSIONS:":[107],"Our":[108],"results":[109],"suggest":[110],"direct":[112],"mechanistic":[113],"effect":[114],"faulty":[116],"piRNA":[117],"meiosis":[120],"spermatogenesis":[122],"men,":[124],"ultimately":[125],"leading":[126],"(Funded":[130],"Innovation":[132],"Fund":[133],"Denmark":[134],"others.).":[136]},"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":27},{"year":2023,"cited_by_count":25},{"year":2022,"cited_by_count":23},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2021-08-16T00:00:00"}
