{"id":"https://openalex.org/W3185328232","doi":"https://doi.org/10.1002/9781119730248.ch9","title":"The Molecular Biology of Benign and Malignant Salivary Gland Tumors","display_name":"The Molecular Biology of Benign and Malignant Salivary Gland Tumors","publication_year":2021,"publication_date":"2021-07-23","ids":{"openalex":"https://openalex.org/W3185328232","doi":"https://doi.org/10.1002/9781119730248.ch9","mag":"3185328232"},"language":"en","primary_location":{"id":"doi:10.1002/9781119730248.ch9","doi":"https://doi.org/10.1002/9781119730248.ch9","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781119730248.ch9","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Salivary Gland Pathology","raw_type":"other"},"volume":{"id":"https://openalex.org/W4205286138","display_name":"Salivary Gland Pathology"},"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056175522","display_name":"Randy Todd","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Randy Todd","raw_affiliation_strings":["Private Practice of Oral and Maxillofacial Surgery, Peabody, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Private Practice of Oral and Maxillofacial Surgery, Peabody, MA, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5056175522"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"269","last_page":"299"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11035","display_name":"Salivary Gland Tumors Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11035","display_name":"Salivary Gland Tumors Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salivary-gland-tumors","display_name":"salivary gland tumors","score":0.9990000128746033},{"id":"https://openalex.org/keywords/benign-salivary-gland-tumors","display_name":"benign salivary gland tumor","score":0.8619999885559082},{"id":"https://openalex.org/keywords/malignant-salivary-gland-tumors","display_name":"malignant salivary gland tumors","score":0.9800000190734863},{"id":"https://openalex.org/keywords/tumor-heterogeneity","display_name":"tumor heterogeneity","score":0.671999990940094},{"id":"https://openalex.org/keywords/genomic-instability","display_name":"genomic instability","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.7720000147819519},{"id":"https://openalex.org/keywords/apoptosis-evasion","display_name":"apoptosis evasion","score":0.9739999771118164},{"id":"https://openalex.org/keywords/cell-immortalization","display_name":"cell immortalization","score":0.7649999856948853},{"id":"https://openalex.org/keywords/neovascularization","display_name":"neovascularization","score":0.9660000205039978},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.7419999837875366},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.6880000233650208},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C2778937882","wikidata":"https://www.wikidata.org/wiki/Q134938","display_name":"Salivary gland","level":2,"score":0.8327356576919556},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5756958723068237},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5266951322555542},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.524962842464447},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5140589475631714},{"id":"https://openalex.org/C2778039489","wikidata":"https://www.wikidata.org/wiki/Q3267772","display_name":"Salivary gland cancer","level":3,"score":0.4996352195739746},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.46153032779693604},{"id":"https://openalex.org/C178169997","wikidata":"https://www.wikidata.org/wiki/Q2892636","display_name":"Genome instability","level":4,"score":0.4271358251571655},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42342543601989746},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41559842228889465},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32034939527511597},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.20825424790382385},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.16894355416297913},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12114882469177246},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9781119730248.ch9","doi":"https://doi.org/10.1002/9781119730248.ch9","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781119730248.ch9","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Salivary Gland Pathology","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":288,"referenced_works":["https://openalex.org/W11406027","https://openalex.org/W24765939","https://openalex.org/W38934446","https://openalex.org/W115812004","https://openalex.org/W657424323","https://openalex.org/W1493453469","https://openalex.org/W1497663772","https://openalex.org/W1518607532","https://openalex.org/W1531799662","https://openalex.org/W1564699296","https://openalex.org/W1578768786","https://openalex.org/W1581972855","https://openalex.org/W1621668454","https://openalex.org/W1653357102","https://openalex.org/W1686494338","https://openalex.org/W1804677413","https://openalex.org/W1856715569","https://openalex.org/W1870464448","https://openalex.org/W1891543308","https://openalex.org/W1920433698","https://openalex.org/W1933712116","https://openalex.org/W1964297775","https://openalex.org/W1966203274","https://openalex.org/W1966313764","https://openalex.org/W1967532587","https://openalex.org/W1968310286","https://openalex.org/W1968325328","https://openalex.org/W1968996812","https://openalex.org/W1970741898","https://openalex.org/W1973353249","https://openalex.org/W1974202442","https://openalex.org/W1975425580","https://openalex.org/W1976803021","https://openalex.org/W1978694580","https://openalex.org/W1978921383","https://openalex.org/W1979851457","https://openalex.org/W1979971484","https://openalex.org/W1981917109","https://openalex.org/W1981994444","https://openalex.org/W1982449999","https://openalex.org/W1982509845","https://openalex.org/W1982845946","https://openalex.org/W1983917177","https://openalex.org/W1984099095","https://openalex.org/W1984800459","https://openalex.org/W1984807040","https://openalex.org/W1985127633","https://openalex.org/W1985936687","https://openalex.org/W1985970054","https://openalex.org/W1986449954","https://openalex.org/W1987945855","https://openalex.org/W1988858372","https://openalex.org/W1989103436","https://openalex.org/W1991084966","https://openalex.org/W1991225025","https://openalex.org/W1991592491","https://openalex.org/W1992072835","https://openalex.org/W1993169282","https://openalex.org/W1993181225","https://openalex.org/W1993571705","https://openalex.org/W1995049733","https://openalex.org/W1995860724","https://openalex.org/W1995964987","https://openalex.org/W1996317740","https://openalex.org/W1996935424","https://openalex.org/W1997031688","https://openalex.org/W1997219075","https://openalex.org/W1998051584","https://openalex.org/W1998432526","https://openalex.org/W1998492363","https://openalex.org/W1998735228","https://openalex.org/W2000196730","https://openalex.org/W2002026641","https://openalex.org/W2002176146","https://openalex.org/W2002722426","https://openalex.org/W2003784925","https://openalex.org/W2005459775","https://openalex.org/W2005823843","https://openalex.org/W2006057892","https://openalex.org/W2006792851","https://openalex.org/W2007740875","https://openalex.org/W2007768141","https://openalex.org/W2008255698","https://openalex.org/W2008301561","https://openalex.org/W2010444010","https://openalex.org/W2010495268","https://openalex.org/W2010745110","https://openalex.org/W2011941471","https://openalex.org/W2012114049","https://openalex.org/W2014691022","https://openalex.org/W2015131091","https://openalex.org/W2016562513","https://openalex.org/W2018406388","https://openalex.org/W2018543404","https://openalex.org/W2019737693","https://openalex.org/W2020038836","https://openalex.org/W2021505095","https://openalex.org/W2022151104","https://openalex.org/W2025869795","https://openalex.org/W2026611731","https://openalex.org/W2026967309","https://openalex.org/W2028356422","https://openalex.org/W2029121455","https://openalex.org/W2029782401","https://openalex.org/W2030475554","https://openalex.org/W2031167624","https://openalex.org/W2031954417","https://openalex.org/W2032535154","https://openalex.org/W2032738666","https://openalex.org/W2033848917","https://openalex.org/W2034277114","https://openalex.org/W2035389181","https://openalex.org/W2036026634","https://openalex.org/W2036180305","https://openalex.org/W2038014312","https://openalex.org/W2038681263","https://openalex.org/W2039484130","https://openalex.org/W2041921202","https://openalex.org/W2045061077","https://openalex.org/W2045276278","https://openalex.org/W2045318032","https://openalex.org/W2045791384","https://openalex.org/W2047330128","https://openalex.org/W2047629990","https://openalex.org/W2049351453","https://openalex.org/W2050141762","https://openalex.org/W2050459519","https://openalex.org/W2052015772","https://openalex.org/W2052286628","https://openalex.org/W2052523674","https://openalex.org/W2053799418","https://openalex.org/W2054235809","https://openalex.org/W2054928391","https://openalex.org/W2055271292","https://openalex.org/W2056203481","https://openalex.org/W2056803965","https://openalex.org/W2058102179","https://openalex.org/W2058947587","https://openalex.org/W2059280348","https://openalex.org/W2060665869","https://openalex.org/W2063957132","https://openalex.org/W2064419717","https://openalex.org/W2064924392","https://openalex.org/W2066507207","https://openalex.org/W2067976180","https://openalex.org/W2069071003","https://openalex.org/W2069738344","https://openalex.org/W2070747100","https://openalex.org/W2071828069","https://openalex.org/W2072702976","https://openalex.org/W2074305443","https://openalex.org/W2074765810","https://openalex.org/W2078164756","https://openalex.org/W2078404919","https://openalex.org/W2080202676","https://openalex.org/W2080312092","https://openalex.org/W2081523314","https://openalex.org/W2083227087","https://openalex.org/W2083806035","https://openalex.org/W2086417538","https://openalex.org/W2089380804","https://openalex.org/W2089556772","https://openalex.org/W2089612869","https://openalex.org/W2092384895","https://openalex.org/W2093566298","https://openalex.org/W2093877599","https://openalex.org/W2096514095","https://openalex.org/W2096515667","https://openalex.org/W2098523473","https://openalex.org/W2099823824","https://openalex.org/W2102409841","https://openalex.org/W2103546898","https://openalex.org/W2106479432","https://openalex.org/W2107617387","https://openalex.org/W2108667668","https://openalex.org/W2108912658","https://openalex.org/W2109073778","https://openalex.org/W2109285146","https://openalex.org/W2109363337","https://openalex.org/W2109899991","https://openalex.org/W2115841286","https://openalex.org/W2116112448","https://openalex.org/W2116208810","https://openalex.org/W2117004442","https://openalex.org/W2117692326","https://openalex.org/W2122193579","https://openalex.org/W2124109146","https://openalex.org/W2124578809","https://openalex.org/W2124594893","https://openalex.org/W2125970092","https://openalex.org/W2126191879","https://openalex.org/W2126993701","https://openalex.org/W2127917633","https://openalex.org/W2128585864","https://openalex.org/W2129062251","https://openalex.org/W2129307197","https://openalex.org/W2129618010","https://openalex.org/W2131027386","https://openalex.org/W2133889936","https://openalex.org/W2134344399","https://openalex.org/W2135067095","https://openalex.org/W2135141560","https://openalex.org/W2136174986","https://openalex.org/W2136309616","https://openalex.org/W2136825655","https://openalex.org/W2137038277","https://openalex.org/W2138430072","https://openalex.org/W2140251048","https://openalex.org/W2140860689","https://openalex.org/W2142814081","https://openalex.org/W2144744111","https://openalex.org/W2146442501","https://openalex.org/W2146775152","https://openalex.org/W2146916102","https://openalex.org/W2149934092","https://openalex.org/W2153459501","https://openalex.org/W2153689503","https://openalex.org/W2153805210","https://openalex.org/W2154281042","https://openalex.org/W2155320075","https://openalex.org/W2156654723","https://openalex.org/W2157782363","https://openalex.org/W2162614825","https://openalex.org/W2163932654","https://openalex.org/W2163947995","https://openalex.org/W2165376335","https://openalex.org/W2166786962","https://openalex.org/W2171134090","https://openalex.org/W2171333146","https://openalex.org/W2178274441","https://openalex.org/W2184718393","https://openalex.org/W2235222438","https://openalex.org/W2288580635","https://openalex.org/W2320201685","https://openalex.org/W2331890757","https://openalex.org/W2333879941","https://openalex.org/W2334527906","https://openalex.org/W2338774035","https://openalex.org/W2340306709","https://openalex.org/W2345120859","https://openalex.org/W2397768453","https://openalex.org/W2416902510","https://openalex.org/W2464731156","https://openalex.org/W2466163601","https://openalex.org/W2510884800","https://openalex.org/W2511504476","https://openalex.org/W2512039535","https://openalex.org/W2548563061","https://openalex.org/W2548704628","https://openalex.org/W2560997559","https://openalex.org/W2564603714","https://openalex.org/W2574394960","https://openalex.org/W2584830174","https://openalex.org/W2591371213","https://openalex.org/W2593119424","https://openalex.org/W2593657144","https://openalex.org/W2596539906","https://openalex.org/W2601742826","https://openalex.org/W2729429885","https://openalex.org/W2766313151","https://openalex.org/W2768184644","https://openalex.org/W2770994361","https://openalex.org/W2774796889","https://openalex.org/W2778981215","https://openalex.org/W2780555702","https://openalex.org/W2789206404","https://openalex.org/W2795531081","https://openalex.org/W2800568674","https://openalex.org/W2802516505","https://openalex.org/W2809951856","https://openalex.org/W2883392009","https://openalex.org/W2886288155","https://openalex.org/W2888048953","https://openalex.org/W2888554859","https://openalex.org/W2895656753","https://openalex.org/W2896786673","https://openalex.org/W2905330119","https://openalex.org/W2913332124","https://openalex.org/W2918687259","https://openalex.org/W2936403605","https://openalex.org/W2938610435","https://openalex.org/W2950832640","https://openalex.org/W2969280790","https://openalex.org/W2981060697","https://openalex.org/W2996152255","https://openalex.org/W2996790322","https://openalex.org/W4230026896","https://openalex.org/W4254638729"],"related_works":["https://openalex.org/W4409605621","https://openalex.org/W7117518633","https://openalex.org/W4244929775","https://openalex.org/W2762551492","https://openalex.org/W2246897826","https://openalex.org/W2904407460","https://openalex.org/W3119500089","https://openalex.org/W2419274370","https://openalex.org/W3006546454","https://openalex.org/W2410879496"],"abstract_inverted_index":{"Benign":[0],"and":[1,9,50,72,75],"malignant":[2],"salivary":[3,21,61],"gland":[4,22,62],"tumors":[5],"are":[6,17],"highly":[7],"complex":[8],"heterogeneous":[10],"tumors.":[11],"Alterations":[12],"of":[13,25,42,54,82],"key":[14],"regulatory":[15],"molecules":[16],"crucial":[18],"events":[19,58],"in":[20,32],"tumorigenesis.":[23],"Abrogation":[24],"these":[26],"regulators":[27],"leads":[28],"to":[29,60,67],"important":[30],"changes":[31],"cellular":[33],"attributes,":[34],"including":[35],"genomic":[36],"instability,":[37],"enhanced":[38],"proliferative":[39],"capacity,":[40],"evasion":[41],"apoptosis,":[43],"immortalization,":[44],"neovascularization,":[45],"as":[46,48],"well":[47],"invasion":[49],"metastasis.":[51],"An":[52],"understanding":[53],"the":[55],"critical":[56],"molecular":[57],"leading":[59],"tumor":[63],"development":[64],"will":[65],"continue":[66],"uncover":[68],"novel":[69],"single":[70],"gene-":[71],"pathway-based":[73],"diagnostic":[74],"therapeutic":[76],"strategies,":[77],"allowing":[78],"targeted,":[79],"personalized":[80],"management":[81],"this":[83],"patient":[84],"population.":[85]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-08-02T00:00:00"}