{"id":"https://openalex.org/W3177650226","doi":"https://doi.org/10.3389/fncir.2021.716408","title":"Prefrontal GABAergic Interneurons Gate Long-Range Afferents to Regulate Prefrontal Cortex-Associated Complex Behaviors","display_name":"Prefrontal GABAergic Interneurons Gate Long-Range Afferents to Regulate Prefrontal Cortex-Associated Complex Behaviors","publication_year":2021,"publication_date":"2021-07-12","ids":{"openalex":"https://openalex.org/W3177650226","doi":"https://doi.org/10.3389/fncir.2021.716408","mag":"3177650226","pmid":"https://pubmed.ncbi.nlm.nih.gov/34322002","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8313241"},"language":"en","primary_location":{"id":"doi:10.3389/fncir.2021.716408","doi":"https://doi.org/10.3389/fncir.2021.716408","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncir.2021.716408","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncir.2021.716408/pdf","source":{"id":"https://openalex.org/S73252628","display_name":"Frontiers in Neural Circuits","issn_l":"1662-5110","issn":["1662-5110"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neural Circuits","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fncir.2021.716408/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102725859","display_name":"Sha-Sha Yang","orcid":"https://orcid.org/0000-0001-6189-8000","observed_orcids":["https://orcid.org/0000-0001-6189-8000"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Sha-Sha Yang","raw_affiliation_strings":["Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, United States","Institute for Translational Brain Research, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, United States","institution_ids":["https://openalex.org/I72816309"]},{"raw_affiliation_string":"Institute for Translational Brain Research, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061277331","display_name":"Nancy R. Mack","orcid":"https://orcid.org/0000-0002-4126-1536","observed_orcids":["https://orcid.org/0000-0002-4126-1536"]},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy R. Mack","raw_affiliation_strings":["Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, United States","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112019019","display_name":"Yousheng Shu","orcid":"https://orcid.org/0000-0002-2834-2876","observed_orcids":["https://orcid.org/0000-0002-2834-2876"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yousheng Shu","raw_affiliation_strings":["Institute for Translational Brain Research, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Translational Brain Research, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021175176","display_name":"Wen\u2010Jun Gao","orcid":"https://orcid.org/0000-0002-8585-3082","observed_orcids":["https://orcid.org/0000-0002-8585-3082"]},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wen-Jun Gao","raw_affiliation_strings":["Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, United States","institution_ids":["https://openalex.org/I72816309"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5021175176"],"corresponding_institution_ids":["https://openalex.org/I72816309"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.7257,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.62027158,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"15","issue":null,"first_page":"716408","last_page":"716408"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.8579000234603882,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.8579000234603882,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.08940000087022781,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.022099999710917473,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"prefrontal cortex","score":0.9210000038146973},{"id":"https://openalex.org/keywords/gabaergic-interneurons","display_name":"GABAergic interneurons","score":1.0},{"id":"https://openalex.org/keywords/parvalbumin-positive-interneurons","display_name":"parvalbumin interneurons","score":0.925000011920929},{"id":"https://openalex.org/keywords/somatostatin-interneurons","display_name":"somatostatin interneurons","score":1.0},{"id":"https://openalex.org/keywords/mediodorsal-thalamic-nucleus","display_name":"mediodorsal thalamus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/ventral-hippocampus","display_name":"ventral hippocampus","score":0.9940000176429749},{"id":"https://openalex.org/keywords/basolateral-amygdala","display_name":"basolateral amygdala","score":0.9990000128746033},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.8209999799728394},{"id":"https://openalex.org/keywords/fear-expression","display_name":"fear expression","score":0.8790000081062317},{"id":"https://openalex.org/keywords/fear-conditioning","display_name":"fear conditioning","score":0.9940000176429749}],"concepts":[{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.9034695625305176},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.8367147445678711},{"id":"https://openalex.org/C2779177108","wikidata":"https://www.wikidata.org/wiki/Q18356742","display_name":"GABAergic","level":3,"score":0.6769830584526062},{"id":"https://openalex.org/C2779296341","wikidata":"https://www.wikidata.org/wiki/Q1500732","display_name":"Interneuron","level":3,"score":0.6630462408065796},{"id":"https://openalex.org/C141547260","wikidata":"https://www.wikidata.org/wiki/Q2720322","display_name":"Parvalbumin","level":2,"score":0.6147635579109192},{"id":"https://openalex.org/C2780451725","wikidata":"https://www.wikidata.org/wiki/Q4867818","display_name":"Basolateral amygdala","level":3,"score":0.6029877066612244},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.5466766953468323},{"id":"https://openalex.org/C50738837","wikidata":"https://www.wikidata.org/wiki/Q781492","display_name":"Optogenetics","level":2,"score":0.5225709676742554},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4881892800331116},{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.4338573217391968},{"id":"https://openalex.org/C2779246727","wikidata":"https://www.wikidata.org/wiki/Q184215","display_name":"Thalamus","level":2,"score":0.4277001619338989},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.3806564211845398},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.29172083735466003},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.22118458151817322}],"mesh":[{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005239","descriptor_name":"Fear","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010320","descriptor_name":"Parvalbumins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012919","descriptor_name":"Social Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013004","descriptor_name":"Somatostatin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D059330","descriptor_name":"GABAergic Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3389/fncir.2021.716408","doi":"https://doi.org/10.3389/fncir.2021.716408","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncir.2021.716408","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncir.2021.716408/pdf","source":{"id":"https://openalex.org/S73252628","display_name":"Frontiers in Neural Circuits","issn_l":"1662-5110","issn":["1662-5110"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neural Circuits","raw_type":"journal-article"},{"id":"pmid:34322002","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34322002","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neural circuits","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8313241","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8313241/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neural Circuits","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:178e0aff0d9a45a6a8567fe199b146ed","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/178e0aff0d9a45a6a8567fe199b146ed","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neural Circuits, Vol 15 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fncir.2021.716408","doi":"https://doi.org/10.3389/fncir.2021.716408","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncir.2021.716408","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncir.2021.716408/pdf","source":{"id":"https://openalex.org/S73252628","display_name":"Frontiers in Neural Circuits","issn_l":"1662-5110","issn":["1662-5110"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neural Circuits","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4000000059604645}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1361137674","display_name":"Roles of NMDA receptors in schizophrenia pathological process","funder_award_id":"R21MH079117","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G4038418272","display_name":"Targeting parvalbumin neurons in the PFC for cognitive deficits","funder_award_id":"R21MH111609","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G651013187","display_name":"Role of prefrontal cortical dopamine in aggression","funder_award_id":"R21MH110678","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G8486403300","display_name":"Development of NMDAR hypofunction and cognitive deficits","funder_award_id":"R01MH085666","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000907600","display_name":"Corticothalamic control of social motivation","funder_award_id":"R01MH131053","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3177650226.pdf","grobid_xml":"https://content.openalex.org/works/W3177650226.grobid-xml"},"referenced_works_count":151,"referenced_works":["https://openalex.org/W52313541","https://openalex.org/W1015756911","https://openalex.org/W1489513029","https://openalex.org/W1525373779","https://openalex.org/W1541267199","https://openalex.org/W1575194766","https://openalex.org/W1576349452","https://openalex.org/W1635887916","https://openalex.org/W1654207600","https://openalex.org/W1838981072","https://openalex.org/W1963854355","https://openalex.org/W1965930842","https://openalex.org/W1970719523","https://openalex.org/W1973417662","https://openalex.org/W1974162322","https://openalex.org/W1977502547","https://openalex.org/W1979339074","https://openalex.org/W1979487363","https://openalex.org/W1988302512","https://openalex.org/W1988418074","https://openalex.org/W1989513272","https://openalex.org/W1990397347","https://openalex.org/W1996642120","https://openalex.org/W1997603362","https://openalex.org/W1997649998","https://openalex.org/W2004159545","https://openalex.org/W2004377368","https://openalex.org/W2004928159","https://openalex.org/W2007430976","https://openalex.org/W2011435312","https://openalex.org/W2011504521","https://openalex.org/W2013315125","https://openalex.org/W2023467429","https://openalex.org/W2025319978","https://openalex.org/W2025603247","https://openalex.org/W2027691566","https://openalex.org/W2031515363","https://openalex.org/W2032658084","https://openalex.org/W2037643842","https://openalex.org/W2039170261","https://openalex.org/W2039641259","https://openalex.org/W2040527392","https://openalex.org/W2042894925","https://openalex.org/W2043517633","https://openalex.org/W2047969788","https://openalex.org/W2048168580","https://openalex.org/W2050618347","https://openalex.org/W2050659319","https://openalex.org/W2052610531","https://openalex.org/W2052765228","https://openalex.org/W2054821149","https://openalex.org/W2057856461","https://openalex.org/W2057967101","https://openalex.org/W2061681507","https://openalex.org/W2064708897","https://openalex.org/W2065738753","https://openalex.org/W2067330935","https://openalex.org/W2071054798","https://openalex.org/W2072652550","https://openalex.org/W2076702669","https://openalex.org/W2077455126","https://openalex.org/W2083889011","https://openalex.org/W2087129491","https://openalex.org/W2088069569","https://openalex.org/W2090275517","https://openalex.org/W2090579112","https://openalex.org/W2093882422","https://openalex.org/W2096050184","https://openalex.org/W2098070616","https://openalex.org/W2110156807","https://openalex.org/W2111161101","https://openalex.org/W2117141679","https://openalex.org/W2120708979","https://openalex.org/W2122614545","https://openalex.org/W2125788186","https://openalex.org/W2126281826","https://openalex.org/W2126520022","https://openalex.org/W2129032286","https://openalex.org/W2130788161","https://openalex.org/W2139168702","https://openalex.org/W2141556360","https://openalex.org/W2141747781","https://openalex.org/W2141787834","https://openalex.org/W2144903814","https://openalex.org/W2147535409","https://openalex.org/W2150418119","https://openalex.org/W2153821084","https://openalex.org/W2158721925","https://openalex.org/W2162459454","https://openalex.org/W2171953485","https://openalex.org/W2177669431","https://openalex.org/W2184917663","https://openalex.org/W2320983896","https://openalex.org/W2336554223","https://openalex.org/W2345112163","https://openalex.org/W2490933581","https://openalex.org/W2511715626","https://openalex.org/W2513790010","https://openalex.org/W2519305421","https://openalex.org/W2525578234","https://openalex.org/W2531096663","https://openalex.org/W2550357178","https://openalex.org/W2558342721","https://openalex.org/W2582869721","https://openalex.org/W2595960708","https://openalex.org/W2599116301","https://openalex.org/W2610186267","https://openalex.org/W2611485120","https://openalex.org/W2751012569","https://openalex.org/W2767578348","https://openalex.org/W2767851849","https://openalex.org/W2769987702","https://openalex.org/W2774489697","https://openalex.org/W2783999012","https://openalex.org/W2790911856","https://openalex.org/W2795970460","https://openalex.org/W2797856206","https://openalex.org/W2801290777","https://openalex.org/W2804163950","https://openalex.org/W2810330189","https://openalex.org/W2893120089","https://openalex.org/W2894521163","https://openalex.org/W2895687586","https://openalex.org/W2896362483","https://openalex.org/W2899355491","https://openalex.org/W2905501654","https://openalex.org/W2907341743","https://openalex.org/W2911706394","https://openalex.org/W2921327779","https://openalex.org/W2921744971","https://openalex.org/W2938741386","https://openalex.org/W2944024410","https://openalex.org/W2949112906","https://openalex.org/W2950040155","https://openalex.org/W2953876999","https://openalex.org/W2954786672","https://openalex.org/W2970759956","https://openalex.org/W2980542075","https://openalex.org/W2983119631","https://openalex.org/W2995488791","https://openalex.org/W3005544203","https://openalex.org/W3006798069","https://openalex.org/W3012733182","https://openalex.org/W3024584290","https://openalex.org/W3027908046","https://openalex.org/W3028406421","https://openalex.org/W3038915190","https://openalex.org/W3121962410","https://openalex.org/W3127550185","https://openalex.org/W3144330946","https://openalex.org/W6792391515"],"related_works":["https://openalex.org/W2016773545","https://openalex.org/W2954786672","https://openalex.org/W2067330935","https://openalex.org/W1989513272","https://openalex.org/W2513790010","https://openalex.org/W7066609483","https://openalex.org/W7117646167","https://openalex.org/W4296663362","https://openalex.org/W2801290777","https://openalex.org/W2948270687"],"abstract_inverted_index":{"Prefrontal":[0],"cortical":[1],"GABAergic":[2,122],"interneurons":[3,199],"(INs)":[4],"and":[5,22,48,139,154,164,204],"their":[6],"innervations":[7],"are":[8,28,60],"essential":[9],"for":[10],"the":[11,37,54,73,87,96,112,134,170,181],"execution":[12],"of":[13,57,64,82,95,104,115,136,191],"complex":[14,202],"behaviors":[15,203],"such":[16,40],"as":[17,41],"working":[18,162],"memory,":[19],"social":[20],"behavior,":[21],"fear":[23,165,176],"expression.":[24,166],"These":[25],"behavior":[26],"regulations":[27],"highly":[29],"dependent":[30],"on":[31,120,125,133,197],"primary":[32],"long-range":[33,84,117,194],"afferents":[34,85,159],"originating":[35],"from":[36,86],"subcortical":[38],"structures":[39],"mediodorsal":[42],"thalamus":[43],"(MD),":[44],"ventral":[45],"hippocampus":[46],"(vHPC),":[47],"basolateral":[49],"amygdala":[50],"(BLA).":[51],"In":[52],"turn,":[53],"regulatory":[55],"effects":[56],"these":[58,83],"inputs":[59,118,195],"mediated":[61],"by":[62,180],"activation":[63],"parvalbumin-expressing":[65],"(PV)":[66],"and/or":[67],"somatostatin":[68],"expressing":[69],"(SST)":[70],"INs":[71,141,156],"within":[72],"prefrontal":[74,97,121,137,152,173,198],"cortex":[75],"(PFC).":[76],"Here":[77],"we":[78,109,131,168],"review":[79,185],"how":[80,151,192,210],"each":[81],"MD,":[88],"vHPC,":[89],"or":[90],"BLA":[91],"recruits":[92],"a":[93,188],"subset":[94],"interneuron":[98],"population":[99],"to":[100,200,208],"exert":[101],"precise":[102],"control":[103],"specific":[105],"PFC-dependent":[106],"behaviors.":[107,147,214],"Specifically,":[108],"first":[110],"summarize":[111],"anatomical":[113],"connections":[114],"different":[116,213],"formed":[119],"INs,":[123],"focusing":[124],"PV":[126],"versus":[127],"SST":[128],"cells.":[129],"Next,":[130],"elaborate":[132],"role":[135],"PV-":[138,153],"SST-":[140,155],"in":[142,160],"regulating":[143],"MD":[144],"afferents-mediated":[145],"cognitive":[146],"We":[148],"also":[149],"examine":[150],"gate":[157],"vHPC":[158],"spatial":[161],"memory":[163],"Finally,":[167],"discuss":[169],"possibility":[171],"that":[172],"PV-INs":[174],"mediate":[175],"conditioning,":[177],"predominantly":[178],"driven":[179],"BLA-mPFC":[182],"pathway.":[183],"This":[184],"will":[186],"provide":[187],"broad":[189],"view":[190],"multiple":[193],"converge":[196],"regulate":[201],"novel":[205],"future":[206],"directions":[207],"understand":[209],"PFC":[211],"controls":[212]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-07-19T00:00:00"}