{"id":"https://openalex.org/W3176350692","doi":"https://doi.org/10.1096/fasebj.26.1_supplement.886.10","title":"Decreased expression of adipose fatty acid transporters CD36 and FATP1 contributes to increased plasma free fatty acids during prolonged fasting in northern elephant seal pups","display_name":"Decreased expression of adipose fatty acid transporters CD36 and FATP1 contributes to increased plasma free fatty acids during prolonged fasting in northern elephant seal pups","publication_year":2012,"publication_date":"2012-04-01","ids":{"openalex":"https://openalex.org/W3176350692","doi":"https://doi.org/10.1096/fasebj.26.1_supplement.886.10","mag":"3176350692"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.26.1_supplement.886.10","doi":"https://doi.org/10.1096/fasebj.26.1_supplement.886.10","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.26.1_supplement.886.10","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027194539","display_name":"Jose Abraham Viscarra","orcid":"https://orcid.org/0000-0003-1273-4098","observed_orcids":["https://orcid.org/0000-0003-1273-4098"]},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose Abraham Viscarra","raw_affiliation_strings":["<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","1--> School of Natural Sciences University of California Merced Merced CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]},{"raw_affiliation_string":"1--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059104619","display_name":"Rub\u00e9n Rodr\u00edguez","orcid":"https://orcid.org/0000-0001-8174-2556","observed_orcids":["https://orcid.org/0000-0001-8174-2556"]},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruben Rodriguez","raw_affiliation_strings":["<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","1--> School of Natural Sciences University of California Merced Merced CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]},{"raw_affiliation_string":"1--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027325862","display_name":"Jos\u00e9 Pablo V\u00e1zquez\u2010Medina","orcid":"https://orcid.org/0000-0003-1014-5214","observed_orcids":["https://orcid.org/0000-0003-1014-5214"]},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose Pablo Vazquez-Medina","raw_affiliation_strings":["<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","1--> School of Natural Sciences University of California Merced Merced CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]},{"raw_affiliation_string":"1--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044842106","display_name":"Cory D. Champagne","orcid":"https://orcid.org/0000-0003-3938-4462","observed_orcids":["https://orcid.org/0000-0003-3938-4462"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cory D. Champagne","raw_affiliation_strings":["<!--<label><sup>2</sup></label>--> Long Marine Laboratory University of California Santa Cruz Santa Cruz CA","2--> Long Marine Laboratory University of California Santa Cruz Santa Cruz CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--<label><sup>2</sup></label>--> Long Marine Laboratory University of California Santa Cruz Santa Cruz CA","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"2--> Long Marine Laboratory University of California Santa Cruz Santa Cruz CA","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061461109","display_name":"Sean H. Adams","orcid":"https://orcid.org/0000-0002-9515-2319","observed_orcids":["https://orcid.org/0000-0002-9515-2319"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sean H Adams","raw_affiliation_strings":["<!--<label><sup>3</sup></label>--> University of California Davis Davis CA","3--> University of California Davis Davis CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--<label><sup>3</sup></label>--> University of California Davis Davis CA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"3--> University of California Davis Davis CA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059327277","display_name":"Daniel E. Crocker","orcid":"https://orcid.org/0000-0002-7940-8011","observed_orcids":["https://orcid.org/0000-0002-7940-8011"]},"institutions":[{"id":"https://openalex.org/I158011677","display_name":"Sonoma State University","ror":"https://ror.org/04wjxkk25","country_code":"US","type":"education","lineage":["https://openalex.org/I158011677"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel E Crocker","raw_affiliation_strings":["<!--<label><sup>4</sup></label>--> Department of Biology Sonoma State University Rohnert Park CA","4--> Department of Biology Sonoma State University Rohnert Park CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--<label><sup>4</sup></label>--> Department of Biology Sonoma State University Rohnert Park CA","institution_ids":["https://openalex.org/I158011677"]},{"raw_affiliation_string":"4--> Department of Biology Sonoma State University Rohnert Park CA","institution_ids":["https://openalex.org/I158011677"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036162154","display_name":"Rudy Martin Ortiz","orcid":"https://orcid.org/0000-0003-3715-7194","observed_orcids":["https://orcid.org/0000-0003-3715-7194"]},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rudy M. Ortiz","raw_affiliation_strings":["<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","1--> School of Natural Sciences University of California Merced Merced CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--<label><sup>1</sup></label>--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]},{"raw_affiliation_string":"1--> School of Natural Sciences University of California Merced Merced CA","institution_ids":["https://openalex.org/I156087764"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35081967,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.8794000148773193,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.8794000148773193,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.047200001776218414,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12745","display_name":"Dietary Effects on Health","score":0.02630000002682209,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/northern-elephant-seal","display_name":"northern elephant seal","score":0.9829999804496765},{"id":"https://openalex.org/keywords/fasting","display_name":"fasting","score":0.7570000290870667},{"id":"https://openalex.org/keywords/plasma-free-fatty-acids","display_name":"plasma free fatty acids","score":0.9610000252723694},{"id":"https://openalex.org/keywords/cd36","display_name":"CD36","score":0.8799999952316284},{"id":"https://openalex.org/keywords/fatp1","display_name":"FATP1","score":0.9710000157356262},{"id":"https://openalex.org/keywords/fatty-acid-transporters","display_name":"fatty acid transporters","score":0.8429999947547913},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7329999804496765},{"id":"https://openalex.org/keywords/lipolysis","display_name":"lipolysis","score":0.8240000009536743},{"id":"https://openalex.org/keywords/fatty-acid-oxidation","display_name":"fatty acid oxidation","score":0.7039999961853027},{"id":"https://openalex.org/keywords/glucose-tolerance-test","display_name":"glucose tolerance test","score":0.7440000176429749},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.6449999809265137},{"id":"https://openalex.org/keywords/pepck-c","display_name":"PEPCK-C","score":0.6430000066757202},{"id":"https://openalex.org/keywords/fas","display_name":"Fas","score":0.7239999771118164}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8918169140815735},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8645385503768921},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.7434200048446655},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7306849360466003},{"id":"https://openalex.org/C140985366","wikidata":"https://www.wikidata.org/wiki/Q898489","display_name":"Lipolysis","level":3,"score":0.7192232012748718},{"id":"https://openalex.org/C2779828298","wikidata":"https://www.wikidata.org/wiki/Q4035577","display_name":"CD36","level":3,"score":0.6677883863449097},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.5699676275253296},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.5185897350311279},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5000786781311035},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.46543848514556885},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.34465041756629944},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33984410762786865},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15029838681221008},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.143397718667984},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.26.1_supplement.886.10","doi":"https://doi.org/10.1096/fasebj.26.1_supplement.886.10","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.26.1_supplement.886.10","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6348781400","display_name":"Mechanisms of Oxidative Stress and Inflammation during Prolonged Fasting and Slee","funder_award_id":"R01HL091767","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2107989915","https://openalex.org/W3177201844","https://openalex.org/W3173471490","https://openalex.org/W2599175437","https://openalex.org/W2232619687","https://openalex.org/W95954219","https://openalex.org/W3193229455","https://openalex.org/W1988699731","https://openalex.org/W2114030178","https://openalex.org/W1964848585"],"abstract_inverted_index":{"The":[0],"northern":[1],"elephant":[2],"seal":[3],"endures":[4],"a":[5,199],"2\u20133":[6],"month":[7],"fast":[8],"during":[9],"which":[10,211],"it":[11],"depends":[12],"primarily":[13],"on":[14,57,66,95,109],"the":[15,36,62,73,77,89,138,161,168,181],"oxidation":[16],"of":[17,38,64,72,91,140,170,184,202],"fatty":[18,27,190],"acids":[19],"to":[20,49,180,197],"meet":[21],"its":[22],"energetic":[23],"demands.":[24],"Plasma":[25,44,121],"free":[26],"acid":[28,191],"(FFA)":[29],"concentration":[30],"increases":[31],"and":[32,93,99,105,114,123,137,144,165,186,215],"is":[33,85],"associated":[34],"with":[35],"onset":[37,169],"insulin":[39,172],"resistance":[40,173],"in":[41,79,82,127,149,174,188,193,204],"late\u2010fasted":[42,83,194],"pups.":[43,120],"FFA":[45,81],"concentrations":[46],"respond":[47],"differentially":[48],"an":[50],"intravenous":[51],"glucose":[52,65,94,208],"tolerance":[53],"test":[54],"(ivGTT)":[55],"depending":[56],"fasting":[58,92,178],"duration":[59],"suggesting":[60],"that":[61],"effects":[63],"lipid":[67,96],"metabolism":[68],"are":[69],"altered.":[70],"Elucidation":[71],"mechanisms":[74],"responsible":[75],"for":[76,167,209],"increase":[78],"plasma":[80,100,153],"seals":[84],"lacking.":[86],"To":[87],"assess":[88],"impact":[90],"metabolism,":[97],"adipose":[98,132],"samples":[101],"were":[102],"collected":[103],"before":[104],"after":[106],"GTTs,":[107],"performed":[108],"early":[110],"(2":[111],"weeks,":[112],"n=5)":[113],"late":[115],"(6\u20138":[116],"weeks;":[117],"n=8)":[118],"fasted":[119,128],"triglycerides":[122],"FFAs":[124],"increased":[125,152],"post\u2010GTT":[126],"seals.":[129],"Fasting":[130,151],"decreased":[131],"lipase":[133,154],"activity":[134,155],"by":[135,220],"50%":[136],"expressions":[139],"CD36,":[141],"FAS,":[142],"FATP1":[143],"PEPCK\u2010C":[145],"22":[146],"\u2010":[147],"43%":[148],"adipose.":[150],"2\u2010":[156],"fold.":[157],"These":[158],"results":[159],"present":[160],"probable":[162],"cause":[163],"of,":[164],"reason":[166],"fasting\u2010induced":[171],"adapted":[175],"mammals,":[176],"as":[177],"leads":[179],"altered":[182],"regulation":[183],"lipolysis":[185],"reduction":[187],"tissue":[189],"uptake":[192],"pups,":[195],"likely":[196],"ensure":[198],"constant":[200],"supply":[201],"lipids":[203,214],"plasma,":[205],"while":[206],"conserving":[207],"tissues":[210],"cannot":[212],"metabolize":[213],"sparing":[216],"lean":[217],"tissue.":[218],"Funded":[219],"NIH":[221],"HL91767":[222]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2021-07-05T00:00:00"}