{"id":"https://openalex.org/W3175438079","doi":"https://doi.org/10.1016/j.asmr.2021.03.020","title":"Cartilage Restoration for Tibiofemoral Bipolar Lesions Results in Promising Failure Rates: A Systematic Review","display_name":"Cartilage Restoration for Tibiofemoral Bipolar Lesions Results in Promising Failure Rates: A Systematic Review","publication_year":2021,"publication_date":"2021-06-24","ids":{"openalex":"https://openalex.org/W3175438079","doi":"https://doi.org/10.1016/j.asmr.2021.03.020","mag":"3175438079","pmid":"https://pubmed.ncbi.nlm.nih.gov/34430903"},"language":"en","primary_location":{"id":"doi:10.1016/j.asmr.2021.03.020","doi":"https://doi.org/10.1016/j.asmr.2021.03.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.asmr.2021.03.020","pdf_url":"http://arthroscopysportsmedicineandrehabilitation.org/article/S2666061X21000729/pdf","source":{"id":"https://openalex.org/S4210234811","display_name":"Arthroscopy Sports Medicine and Rehabilitation","issn_l":"2666-061X","issn":["2666-061X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthroscopy, Sports Medicine, and Rehabilitation","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://arthroscopysportsmedicineandrehabilitation.org/article/S2666061X21000729/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071101746","display_name":"Anirudh K. Gowd","orcid":"https://orcid.org/0000-0001-7151-6459","observed_orcids":["https://orcid.org/0000-0001-7151-6459"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anirudh K. Gowd","raw_affiliation_strings":["Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","institution_ids":["https://openalex.org/I1282516798"]},{"raw_affiliation_string":"Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038599439","display_name":"Alexander E. Weimer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander E. Weimer","raw_affiliation_strings":["Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","institution_ids":["https://openalex.org/I1282516798"]},{"raw_affiliation_string":"Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045291684","display_name":"Danielle E. Rider","orcid":"https://orcid.org/0000-0003-4430-7066","observed_orcids":["https://orcid.org/0000-0003-4430-7066"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danielle E. Rider","raw_affiliation_strings":["Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","institution_ids":["https://openalex.org/I1282516798"]},{"raw_affiliation_string":"Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009336062","display_name":"Edward C. Beck","orcid":"https://orcid.org/0000-0002-5092-0679","observed_orcids":["https://orcid.org/0000-0002-5092-0679"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward C. Beck","raw_affiliation_strings":["Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","institution_ids":["https://openalex.org/I1282516798"]},{"raw_affiliation_string":"Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064247410","display_name":"Avinesh Agarwalla","orcid":"https://orcid.org/0000-0001-5056-6780","observed_orcids":["https://orcid.org/0000-0001-5056-6780"]},"institutions":[{"id":"https://openalex.org/I1321686444","display_name":"Westchester Medical Center","ror":"https://ror.org/03fcgva33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1321686444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Avinesh Agarwalla","raw_affiliation_strings":["Westchester Medical Center Valhalla New York U.S.A","Westchester Medical Center, Valhalla, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Westchester Medical Center Valhalla New York U.S.A","institution_ids":["https://openalex.org/I1321686444"]},{"raw_affiliation_string":"Westchester Medical Center, Valhalla, New York, U.S.A","institution_ids":["https://openalex.org/I1321686444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072755963","display_name":"Lisa K. O\u2019Brien","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa K. O\u2019Brien","raw_affiliation_strings":["Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","institution_ids":["https://openalex.org/I1282516798"]},{"raw_affiliation_string":"Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054968531","display_name":"Michael Joseph Alaia","orcid":"https://orcid.org/0000-0001-8003-5737","observed_orcids":["https://orcid.org/0000-0001-8003-5737"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Alaia","raw_affiliation_strings":["New York University Langone Health New York New York U.S.A","New York University Langone Health, New York, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Langone Health New York New York U.S.A","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York University Langone Health, New York, New York, U.S.A","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019761310","display_name":"Cristin M. Ferguson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristin M. Ferguson","raw_affiliation_strings":["Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","institution_ids":["https://openalex.org/I1282516798"]},{"raw_affiliation_string":"Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082701563","display_name":"Brian Robert Waterman","orcid":"https://orcid.org/0000-0002-1442-212X","observed_orcids":["https://orcid.org/0000-0002-1442-212X"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian R. Waterman","raw_affiliation_strings":["Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest University Baptist Medical Center Winston\u2010Salem North Carolina U.S.A","institution_ids":["https://openalex.org/I1282516798"]},{"raw_affiliation_string":"Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A","institution_ids":["https://openalex.org/I1282516798"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5071101746"],"corresponding_institution_ids":["https://openalex.org/I1282516798"],"apc_list":{"value":2000,"currency":"USD","value_usd":2000},"apc_paid":{"value":2000,"currency":"USD","value_usd":2000},"fwci":0.2861,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.31097841,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"3","issue":"4","first_page":"e1227","last_page":"e1235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.29760000109672546,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteochondral-allograft-transplantation","display_name":"osteochondral allograft transplantation","score":0.7400000095367432},{"id":"https://openalex.org/keywords/autologous-chondrocyte-implantation","display_name":"autologous chondrocyte implantation","score":0.996999979019165},{"id":"https://openalex.org/keywords/microfracture","display_name":"microfracture","score":0.8270000219345093},{"id":"https://openalex.org/keywords/cartilage-repair","display_name":"cartilage repair","score":0.8849999904632568},{"id":"https://openalex.org/keywords/treatment-failure-rate","display_name":"treatment failure rate","score":0.8349999785423279},{"id":"https://openalex.org/keywords/time-to-failure","display_name":"time to failure","score":0.7940000295639038},{"id":"https://openalex.org/keywords/knee-osteoarthritis","display_name":"knee osteoarthritis","score":0.6980000138282776},{"id":"https://openalex.org/keywords/unicompartmental-knee-arthroplasty","display_name":"unicompartmental knee arthroplasty","score":0.8069999814033508},{"id":"https://openalex.org/keywords/total-knee-arthroplasty","display_name":"total knee arthroplasty","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.6210151314735413},{"id":"https://openalex.org/C2909674901","wikidata":"https://www.wikidata.org/wiki/Q938793","display_name":"Cartilage damage","level":5,"score":0.4698167145252228},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41423502564430237},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.345600962638855},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3437036871910095},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.3332543969154358},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.26843249797821045},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.218995600938797},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.18917664885520935},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.10413035750389099},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.05116578936576843}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.asmr.2021.03.020","doi":"https://doi.org/10.1016/j.asmr.2021.03.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.asmr.2021.03.020","pdf_url":"http://arthroscopysportsmedicineandrehabilitation.org/article/S2666061X21000729/pdf","source":{"id":"https://openalex.org/S4210234811","display_name":"Arthroscopy Sports Medicine and Rehabilitation","issn_l":"2666-061X","issn":["2666-061X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthroscopy, Sports Medicine, and Rehabilitation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8365214","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8365214","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthrosc Sports Med Rehabil","raw_type":"Text"},{"id":"pmid:34430903","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34430903","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthroscopy, sports medicine, and rehabilitation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.asmr.2021.03.020","doi":"https://doi.org/10.1016/j.asmr.2021.03.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.asmr.2021.03.020","pdf_url":"http://arthroscopysportsmedicineandrehabilitation.org/article/S2666061X21000729/pdf","source":{"id":"https://openalex.org/S4210234811","display_name":"Arthroscopy Sports Medicine and Rehabilitation","issn_l":"2666-061X","issn":["2666-061X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthroscopy, Sports Medicine, and Rehabilitation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3175438079.pdf","grobid_xml":"https://content.openalex.org/works/W3175438079.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1964656841","https://openalex.org/W1966481701","https://openalex.org/W1967057044","https://openalex.org/W1987910648","https://openalex.org/W2002176831","https://openalex.org/W2023044679","https://openalex.org/W2024126544","https://openalex.org/W2025317816","https://openalex.org/W2030835954","https://openalex.org/W2035317111","https://openalex.org/W2039367775","https://openalex.org/W2040570057","https://openalex.org/W2043391996","https://openalex.org/W2065497694","https://openalex.org/W2101759648","https://openalex.org/W2105175564","https://openalex.org/W2125714423","https://openalex.org/W2144047185","https://openalex.org/W2151693901","https://openalex.org/W2157823046","https://openalex.org/W2158143099","https://openalex.org/W2159520009","https://openalex.org/W2161701454","https://openalex.org/W2167307573","https://openalex.org/W2170794587","https://openalex.org/W2323225719","https://openalex.org/W2574535024","https://openalex.org/W2739745012","https://openalex.org/W2743608568","https://openalex.org/W2765992259","https://openalex.org/W2791420234","https://openalex.org/W2791539705","https://openalex.org/W2793888944","https://openalex.org/W2803553667","https://openalex.org/W2893015604","https://openalex.org/W2897099256","https://openalex.org/W2898813397","https://openalex.org/W2951723566","https://openalex.org/W2990005222","https://openalex.org/W3009571317","https://openalex.org/W3013810081","https://openalex.org/W4293259412","https://openalex.org/W6749350307"],"related_works":["https://openalex.org/W2517901554","https://openalex.org/W1543785936","https://openalex.org/W2466697336","https://openalex.org/W4403391745","https://openalex.org/W2739159961","https://openalex.org/W2004763015","https://openalex.org/W3133714215","https://openalex.org/W2023955812","https://openalex.org/W2041693344","https://openalex.org/W4318482020"],"abstract_inverted_index":{"Purpose":[0],"The":[1,209,221,236],"purpose":[2],"of":[3,16,66,100,106,218,224,272,280,307,313],"the":[4,11,20,46,64,104,273,287,301],"present":[5],"study":[6,131,289],"is":[7,29,282],"to":[8,83,114,189,239,284],"systematically":[9],"review":[10,312],"available":[12,94],"literature":[13],"for":[14,63,95,303],"management":[15,105],"bipolar":[17,68,107,149,158,270],"lesions":[18,271],"within":[19],"tibiofemoral":[21,26,71,108,274],"joint":[22],"and":[23,36,43,50,52,73,81,97,117,123,134,166,169,176,201,229,244,258,265,296],"determine":[24],"whether":[25],"cartilage":[27],"restoration":[28],"an":[30,215],"effective":[31],"treatment":[32],"modality.":[33],"Methods":[34],"PubMed":[35],"MEDLINE":[37],"databases":[38],"were":[39,61,91,144,180,187,199],"queried":[40],"between":[41,121,227,242,263,294],"2000":[42],"2020":[44],"using":[45],"following":[47],"keywords:":[48],"\u201costeochondral\u201d":[49],"\u201cknee\u201d":[51],"\u201cmicrofracture,\u201d":[53],"\u201cautologous":[54],"chondrocyte":[55],"implantation":[56],"(ACI),\u201d":[57],"or":[58,69,191],"\u201ctransplantation.\"":[59],"Articles":[60],"reviewed":[62],"presence":[65],"a":[67,98,277],"\u201ckissing\u201d":[70],"lesion":[72,75],"reported":[74],"size,":[76],"concomitant":[77],"procedures,":[78],"failure":[79,225,240,261],"rates,":[80],"time":[82,238],"failure.":[84,220],"Results":[85],"After":[86],"screening":[87],"1,295":[88],"articles,":[89],"there":[90],"4":[92,195],"articles":[93],"analysis":[96],"total":[99,192],"152":[101],"knees":[102,146,155,161,171],"involving":[103],"lesions.":[109],"Age":[110],"ranged":[111,226,241],"from":[112],"14":[113],"60":[115],"years,":[116],"mean":[118,222,237],"follow\u2010up":[119],"was":[120,127],"12":[122],"240":[124],"months.":[125],"There":[126,143,179],"1":[128],"retrospective":[129],"cohort":[130],"(36":[132],"knees)":[133],"3":[135],"case":[136],"series":[137],"(mean,":[138],"38.7":[139],"\u00b1":[140],"17.5":[141],"knees).":[142],"58":[145,154],"treated":[147,156,162,172],"with":[148,157,163,173,269],"osteochondral":[150],"allograft":[151],"(OCA)":[152],"transplantation,":[153],"ACI,":[159],"20":[160],"femoral":[164,174],"OCA":[165,175],"tibial":[167,177],"debridement,":[168],"16":[170,184],"microfracture.":[178],"37":[181],"failures":[182,212],"(24.3%):":[183],"patients":[185,203,268],"(10.5%)":[186],"converted":[188],"unicompartmental":[190],"knee":[193],"arthroplasty,":[194],"restorative":[196],"procedures":[197],"(2.6%)":[198],"revised,":[200],"8":[202],"(1.6%)":[204],"had":[205,214,260],"unsatisfactory":[206],"outcomes":[207],"only.":[208],"remaining":[210],"15":[211],"(9.9%)":[213],"unspecified":[216],"combination":[217],"objective":[219],"rate":[223],"0%":[228,264],"44.1%":[230],"(":[231,247],"I":[232,248],"2":[233,249],"=":[234,250],"83.2%).":[235],"2.7":[243],"4.1":[245],"years":[246],"79.1%).":[251],"Conclusions":[252],"Cartilage":[253],"restoration,":[254],"through":[255],"both":[256],"ACI":[257],"OCA,":[259],"rates":[262,293],"44%":[266],"in":[267],"compartment.":[275],"Although":[276],"higher":[278],"level":[279],"evidence":[281],"required":[283],"prove":[285],"efficacy,":[286],"current":[288],"demonstrates":[290],"midterm":[291],"survivorship":[292],"55%":[295],"100%,":[297],"which":[298],"may":[299],"delay":[300],"need":[302],"secondary":[304],"arthroplasty.":[305],"Level":[306,309,314],"Evidence":[308],"IV,":[310],"systematic":[311],"IV":[315],"studies.":[316]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2021-07-05T00:00:00"}