{"id":"https://openalex.org/W3175366876","doi":"https://doi.org/10.1542/peds.2020-042085","title":"First Time Wheezing in a 2-Year-Old","display_name":"First Time Wheezing in a 2-Year-Old","publication_year":2021,"publication_date":"2021-06-22","ids":{"openalex":"https://openalex.org/W3175366876","doi":"https://doi.org/10.1542/peds.2020-042085","mag":"3175366876","pmid":"https://pubmed.ncbi.nlm.nih.gov/34158315"},"language":"en","primary_location":{"id":"doi:10.1542/peds.2020-042085","doi":"https://doi.org/10.1542/peds.2020-042085","is_oa":false,"landing_page_url":"https://doi.org/10.1542/peds.2020-042085","pdf_url":null,"source":{"id":"https://openalex.org/S77494981","display_name":"PEDIATRICS","issn_l":"0031-4005","issn":["0031-4005","1098-4275"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315734","host_organization_name":"American Academy of Pediatrics","host_organization_lineage":["https://openalex.org/P4310315734"],"host_organization_lineage_names":["American Academy of Pediatrics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016008788","display_name":"Luke T. Viehl","orcid":"https://orcid.org/0000-0002-2870-7804","observed_orcids":["https://orcid.org/0000-0002-2870-7804"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luke Viehl","raw_affiliation_strings":["Department of Pediatrics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113698758","display_name":"Michele Estabrook","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michele Estabrook","raw_affiliation_strings":["Department of Pediatrics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020722157","display_name":"Sanjeev Bhalla","orcid":"https://orcid.org/0000-0002-1262-8925","observed_orcids":["https://orcid.org/0000-0002-1262-8925"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sanjeev Bhalla","raw_affiliation_strings":["Mallinckrodt Institute of Radiology, School of Medicine, Washington University in St Louis, St Louis, Missouri"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mallinckrodt Institute of Radiology, School of Medicine, Washington University in St Louis, St Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030411648","display_name":"Chung Lee","orcid":"https://orcid.org/0000-0003-0855-4553","observed_orcids":["https://orcid.org/0000-0003-0855-4553"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chung Lee","raw_affiliation_strings":["Department of Pediatrics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"James Kemp","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James Kemp","raw_affiliation_strings":["Department of Pediatrics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027138500","display_name":"Andrew J. White","orcid":"https://orcid.org/0000-0001-9394-7823","observed_orcids":["https://orcid.org/0000-0001-9394-7823"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Andrew White","raw_affiliation_strings":["Department of Pediatrics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027138500"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09275591,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"148","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11910","display_name":"Foreign Body Medical Cases","score":0.9496999979019165,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11910","display_name":"Foreign Body Medical Cases","score":0.9496999979019165,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11260","display_name":"Tracheal and airway disorders","score":0.02979999966919422,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pediatric-wheezing","display_name":"pediatric wheezing","score":0.6449999809265137},{"id":"https://openalex.org/keywords/reactive-airway-disease","display_name":"reactive airway disease","score":0.8740000128746033},{"id":"https://openalex.org/keywords/viral-bronchiolitis","display_name":"viral bronchiolitis","score":0.9010000228881836},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.6240000128746033},{"id":"https://openalex.org/keywords/persistent-hypoxemia","display_name":"persistent hypoxemia","score":0.675000011920929},{"id":"https://openalex.org/keywords/foreign-body-aspiration","display_name":"foreign body aspiration","score":0.5540000200271606},{"id":"https://openalex.org/keywords/foreign-body-diagnosis","display_name":"foreign body diagnosis","score":0.4749999940395355},{"id":"https://openalex.org/keywords/rigid-bronchoscopy","display_name":"rigid bronchoscopy","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C2910768427","wikidata":"https://www.wikidata.org/wiki/Q203337","display_name":"Pulmonologist","level":2,"score":0.9868278503417969},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9837616682052612},{"id":"https://openalex.org/C2778821649","wikidata":"https://www.wikidata.org/wiki/Q424227","display_name":"Bronchiolitis","level":3,"score":0.7690317630767822},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.6602468490600586},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.5667696595191956},{"id":"https://openalex.org/C2908861384","wikidata":"https://www.wikidata.org/wiki/Q203337","display_name":"Pulmonologists","level":2,"score":0.4438687860965729},{"id":"https://openalex.org/C2778996910","wikidata":"https://www.wikidata.org/wiki/Q237232","display_name":"Bronchoscopy","level":2,"score":0.44294026494026184},{"id":"https://openalex.org/C2777402568","wikidata":"https://www.wikidata.org/wiki/Q779038","display_name":"Respiratory sounds","level":3,"score":0.4172877073287964},{"id":"https://openalex.org/C2777977376","wikidata":"https://www.wikidata.org/wiki/Q7831316","display_name":"Tracheobronchomalacia","level":3,"score":0.416643887758255},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.395442396402359},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.285835862159729},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.27498653531074524},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18204519152641296}],"mesh":[{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D001999","descriptor_name":"Bronchoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003371","descriptor_name":"Cough","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004621","descriptor_name":"Embolization, Therapeutic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011651","descriptor_name":"Pulmonary Artery","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011651","descriptor_name":"Pulmonary Artery","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":true},{"descriptor_ui":"D012135","descriptor_name":"Respiratory Sounds","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D013683","descriptor_name":"Telangiectasia, Hereditary Hemorrhagic","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013683","descriptor_name":"Telangiectasia, Hereditary Hemorrhagic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D013683","descriptor_name":"Telangiectasia, Hereditary Hemorrhagic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1542/peds.2020-042085","doi":"https://doi.org/10.1542/peds.2020-042085","is_oa":false,"landing_page_url":"https://doi.org/10.1542/peds.2020-042085","pdf_url":null,"source":{"id":"https://openalex.org/S77494981","display_name":"PEDIATRICS","issn_l":"0031-4005","issn":["0031-4005","1098-4275"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315734","host_organization_name":"American Academy of Pediatrics","host_organization_lineage":["https://openalex.org/P4310315734"],"host_organization_lineage_names":["American Academy of Pediatrics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics","raw_type":"journal-article"},{"id":"pmid:34158315","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34158315","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.7400000095367432,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W100533700","https://openalex.org/W1970513876","https://openalex.org/W1991820553","https://openalex.org/W2016718501","https://openalex.org/W2063860651","https://openalex.org/W2075612635","https://openalex.org/W2080299984","https://openalex.org/W2143723459","https://openalex.org/W2144410539","https://openalex.org/W2294639444","https://openalex.org/W3084414092"],"related_works":["https://openalex.org/W2319035648","https://openalex.org/W1034285351","https://openalex.org/W2885653382","https://openalex.org/W4200291684","https://openalex.org/W2410738019","https://openalex.org/W2982695988","https://openalex.org/W4210574346","https://openalex.org/W4255605552","https://openalex.org/W2476646994","https://openalex.org/W2152560391"],"abstract_inverted_index":{"Pediatric":[0],"patients":[1],"with":[2,44,135],"respiratory":[3],"signs":[4],"and":[5,60,81,146,149],"symptoms":[6],"who":[7],"are":[8,24],"found":[9],"to":[10,17,70,79,100,127,143],"be":[11,128],"wheezing":[12,45],"present":[13],"a":[14,42,71,101],"diagnostic":[15],"dilemma":[16],"pediatricians.":[18],"The":[19],"majority":[20],"of":[21,29,51,57,62,115,151],"these":[22],"cases":[23],"diagnosed":[25],"as":[26,34],"some":[27],"degree":[28],"reactive":[30],"airway":[31],"disease,":[32],"either":[33],"viral":[35],"bronchiolitis":[36],"or":[37],"asthma.":[38],"In":[39],"this":[40],"scenario,":[41],"patient":[43],"was":[46,67,92,108,137],"initially":[47],"given":[48],"2":[49],"courses":[50],"appropriate":[52,147],"antibiotics":[53],"on":[54],"the":[55,58,86,95],"basis":[56],"duration":[59],"concurrence":[61],"other":[63],"symptoms.":[64,153],"However,":[65],"he":[66],"subsequently":[68],"referred":[69],"pediatric":[72,96],"pulmonologist":[73],"for":[74],"further":[75],"workup":[76],"after":[77],"failure":[78],"improve":[80],"persistent":[82,121],"oxygen":[83],"saturations":[84,125],"in":[85,98],"low-to-mid":[87],"90s.":[88],"More":[89],"extensive":[90],"testing":[91],"completed":[93],"by":[94],"pulmonologist,":[97],"addition":[99],"short":[102],"hospital":[103],"admission.":[104],"A":[105,130],"rigid":[106],"bronchoscopy":[107],"eventually":[109,141],"completed,":[110,139],"which":[111,140],"revealed":[112],"small":[113],"pieces":[114],"partially":[116],"digested":[117],"material.":[118],"Although":[119],"his":[120,124,144,152],"cough":[122],"resolved,":[123],"continued":[126],"suboptimal.":[129],"chest":[131],"computed":[132],"tomography":[133],"scan":[134],"contrast":[136],"then":[138],"led":[142],"diagnosis":[145],"treatment":[148],"resolution":[150]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-07-05T00:00:00"}