{"id":"https://openalex.org/W3172620533","doi":"https://doi.org/10.46883/onc.2021.3506.0311","title":"Radiotherapy for Oligometastatic Non\u2013Small Cell Lung Cancer: Past, Present, and Future","display_name":"Radiotherapy for Oligometastatic Non\u2013Small Cell Lung Cancer: Past, Present, and Future","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3172620533","doi":"https://doi.org/10.46883/onc.2021.3506.0311","mag":"3172620533","pmid":"https://pubmed.ncbi.nlm.nih.gov/34139791"},"language":"en","primary_location":{"id":"doi:10.46883/onc.2021.3506.0311","doi":"https://doi.org/10.46883/onc.2021.3506.0311","is_oa":false,"landing_page_url":"https://doi.org/10.46883/onc.2021.3506.0311","pdf_url":null,"source":{"id":"https://openalex.org/S4210190768","display_name":"ONCOLOGY","issn_l":"0890-9091","issn":["0890-9091","2767-7389"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-100","russia-white-list-3"],"host_organization":"https://openalex.org/P4320800648","host_organization_name":"MJH Life Sciences","host_organization_lineage":["https://openalex.org/P4320800648"],"host_organization_lineage_names":["MJH Life Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ONCOLOGY","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036226868","display_name":"Neal S. McCall","orcid":"https://orcid.org/0000-0001-7571-6984","observed_orcids":["https://orcid.org/0000-0001-7571-6984"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neal McCall","raw_affiliation_strings":["Winship Cancer Institute, Emory University, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Winship Cancer Institute, Emory University, Atlanta, GA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080256711","display_name":"Kristin Ann Higgins","orcid":"https://orcid.org/0000-0003-1496-9878","observed_orcids":["https://orcid.org/0000-0003-1496-9878"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristin Higgins","raw_affiliation_strings":["Emory University School of Medicine, Atlanta, GA","Winship Cancer Institute, Emory University, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory University School of Medicine, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Winship Cancer Institute, Emory University, Atlanta, GA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1584,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.47000941,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"35","issue":"3506","first_page":"311","last_page":"319"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oligometastatic-non-small-cell-lung-cancer","display_name":"oligometastatic non-small cell lung cancer","score":0.9679999947547913},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.9150000214576721},{"id":"https://openalex.org/keywords/local-ablative-therapy","display_name":"local ablative therapy","score":0.9589999914169312},{"id":"https://openalex.org/keywords/stage-iv-lung-cancer","display_name":"stage IV lung cancer","score":0.828000009059906},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.699999988079071},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.9779999852180481},{"id":"https://openalex.org/keywords/clinical-trials","display_name":"clinical trials","score":0.6629999876022339}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8688195943832397},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.7536740303039551},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6866785287857056},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.6769253015518188},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6703063249588013},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5721025466918945},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5283233523368835},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5094040036201477},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.4967072606086731},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4343668818473816},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4288378357887268},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000078703","descriptor_name":"Radiofrequency Ablation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000078703","descriptor_name":"Radiofrequency Ablation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.46883/onc.2021.3506.0311","doi":"https://doi.org/10.46883/onc.2021.3506.0311","is_oa":false,"landing_page_url":"https://doi.org/10.46883/onc.2021.3506.0311","pdf_url":null,"source":{"id":"https://openalex.org/S4210190768","display_name":"ONCOLOGY","issn_l":"0890-9091","issn":["0890-9091","2767-7389"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-100","russia-white-list-3"],"host_organization":"https://openalex.org/P4320800648","host_organization_name":"MJH Life Sciences","host_organization_lineage":["https://openalex.org/P4320800648"],"host_organization_lineage_names":["MJH Life Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ONCOLOGY","raw_type":"journal-article"},{"id":"pmid:34139791","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34139791","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology (Williston Park, N.Y.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.979200005531311,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1967866280","https://openalex.org/W2049088975","https://openalex.org/W2124164669","https://openalex.org/W2338611117","https://openalex.org/W2792937256","https://openalex.org/W2793097495","https://openalex.org/W2897777582","https://openalex.org/W2911812451","https://openalex.org/W2913745075","https://openalex.org/W2941481974","https://openalex.org/W2995808512","https://openalex.org/W2996630100","https://openalex.org/W3083176429","https://openalex.org/W3092484545","https://openalex.org/W3093923068","https://openalex.org/W3110528877","https://openalex.org/W3131063362","https://openalex.org/W3131211776","https://openalex.org/W3134949580","https://openalex.org/W4233562659","https://openalex.org/W7110819555"],"related_works":["https://openalex.org/W7169672578","https://openalex.org/W3171101139","https://openalex.org/W3157973823","https://openalex.org/W4311866950","https://openalex.org/W2482809663","https://openalex.org/W2977840391","https://openalex.org/W2414261763","https://openalex.org/W2756478990","https://openalex.org/W7154122736","https://openalex.org/W3213859114"],"abstract_inverted_index":{"Historically,":[0],"patients":[1,30,78],"with":[2,13,31,79],"stage":[3],"IV":[4],"non-small":[5],"cell":[6],"lung":[7],"cancer":[8],"(NSCLC)":[9],"have":[10,50],"been":[11],"treated":[12],"chemotherapy":[14],"alone,":[15],"reserving":[16],"local":[17,38],"therapies":[18,40],"for":[19,54],"symptom":[20],"palliation.":[21],"However,":[22],"evidence":[23],"has":[24],"accumulated":[25],"that":[26,49,62],"a":[27],"subset":[28],"of":[29,75,84],"oligometastatic":[32],"NSCLC":[33],"(OM-NSCLC)":[34],"may":[35],"benefit":[36],"from":[37],"ablative":[39],"(LATs).":[41],"In":[42],"this":[43,67],"article,":[44],"we":[45,70],"review":[46],"the":[47,52,59,72,82],"data":[48],"formed":[51],"rationale":[53],"LAT,":[55],"specifically":[56],"radiotherapy,":[57],"and":[58,86],"prospective":[60],"trials":[61,95],"support":[63],"its":[64],"use":[65],"in":[66,77,81,98],"population.":[68],"Finally,":[69],"examine":[71],"evolving":[73],"role":[74],"LAT":[76,97],"OM-NSCLC":[80],"context":[83],"immunotherapy":[85],"targeted":[87],"therapies,":[88],"as":[89,91],"well":[90],"discuss":[92],"ongoing":[93],"clinical":[94],"incorporating":[96],"these":[99],"patients.":[100]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-06-22T00:00:00"}