{"id":"https://openalex.org/W31711463","doi":"https://doi.org/10.1007/978-3-642-50059-6_17","title":"Selective and Neutral Evolution in the Murine Igh-V Locus","display_name":"Selective and Neutral Evolution in the Murine Igh-V Locus","publication_year":1988,"publication_date":"1988-01-01","ids":{"openalex":"https://openalex.org/W31711463","doi":"https://doi.org/10.1007/978-3-642-50059-6_17","mag":"31711463","pmid":"https://pubmed.ncbi.nlm.nih.gov/3138070"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-50059-6_17","doi":"https://doi.org/10.1007/978-3-642-50059-6_17","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-50059-6_17","pdf_url":null,"source":{"id":"https://openalex.org/S192937065","display_name":"Current topics in microbiology and immunology","issn_l":"0070-217X","issn":["0070-217X","2196-9965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Microbiology and Immunology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W619564462","display_name":"Genetics of Immunological Diseases"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"A. Tutter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Tutter","raw_affiliation_strings":["Medical Biology Institute, 92037, La Jolla, CA, USA","University of Pennsylvania, 19104, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Biology Institute, 92037, La Jolla, CA, USA","institution_ids":[]},{"raw_affiliation_string":"University of Pennsylvania, 19104, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024593797","display_name":"Roy J. Riblet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Riblet","raw_affiliation_strings":["Medical Biology Institute, 92037, La Jolla, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Biology Institute, 92037, La Jolla, CA, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1492,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.85152838,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"137","issue":null,"first_page":"107","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.8827999830245972,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.8827999830245972,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.027400000020861626,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.022600000724196434,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunoglobulin-heavy-chain-variable-region","display_name":"immunoglobulin heavy chain variable region","score":0.890999972820282},{"id":"https://openalex.org/keywords/vh-gene-families","display_name":"VH gene families","score":0.6039999723434448},{"id":"https://openalex.org/keywords/gene-family-size","display_name":"gene family size","score":0.6259999871253967},{"id":"https://openalex.org/keywords/copy-number-evolution","display_name":"copy number evolution","score":0.7009999752044678},{"id":"https://openalex.org/keywords/gene-clusters","display_name":"gene clusters","score":0.4449999928474426},{"id":"https://openalex.org/keywords/immunoglobulin-gene-evolution","display_name":"immunoglobulin gene evolution","score":0.652999997138977},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.8254437446594238},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.7140297889709473},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6541794538497925},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6108937859535217},{"id":"https://openalex.org/C96007430","wikidata":"https://www.wikidata.org/wiki/Q3776943","display_name":"Immunoglobulin heavy chain","level":3,"score":0.500908374786377},{"id":"https://openalex.org/C64894306","wikidata":"https://www.wikidata.org/wiki/Q849622","display_name":"Homologous chromosome","level":3,"score":0.45442110300064087},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3335382044315338}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005803","descriptor_name":"Genes, Immunoglobulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007135","descriptor_name":"Immunoglobulin Variable Region","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007143","descriptor_name":"Immunoglobulin Heavy Chains","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-642-50059-6_17","doi":"https://doi.org/10.1007/978-3-642-50059-6_17","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-50059-6_17","pdf_url":null,"source":{"id":"https://openalex.org/S192937065","display_name":"Current topics in microbiology and immunology","issn_l":"0070-217X","issn":["0070-217X","2196-9965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Microbiology and Immunology","raw_type":"book-chapter"},{"id":"pmid:3138070","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3138070","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current topics in microbiology and immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Life on land","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/15"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1597933449","display_name":null,"funder_award_id":"AI 23548","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W8751965","https://openalex.org/W40716719","https://openalex.org/W70594466","https://openalex.org/W140810763","https://openalex.org/W565091882","https://openalex.org/W1927579418","https://openalex.org/W1976168421","https://openalex.org/W1982537459","https://openalex.org/W2002242108","https://openalex.org/W2021940911","https://openalex.org/W2022519461","https://openalex.org/W2030006670","https://openalex.org/W2040152774","https://openalex.org/W2040571417","https://openalex.org/W2055333569","https://openalex.org/W2064836402","https://openalex.org/W2103277835","https://openalex.org/W2118107917","https://openalex.org/W2120513063","https://openalex.org/W2132442049","https://openalex.org/W2164450265","https://openalex.org/W2329176257","https://openalex.org/W3098568188"],"related_works":["https://openalex.org/W7021103547","https://openalex.org/W2081924139","https://openalex.org/W2003160073","https://openalex.org/W999686974","https://openalex.org/W2120513063","https://openalex.org/W7096366053","https://openalex.org/W2117749104","https://openalex.org/W2031867844","https://openalex.org/W2048588036","https://openalex.org/W1940341482"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}