{"id":"https://openalex.org/W3168322326","doi":"https://doi.org/10.22127/rjp.2021.273419.1680","title":"Antibacterial and Antioxidant Activity of Cirsium englerianum (Asteraceae), an Endemic Plant to Ethiopia","display_name":"Antibacterial and Antioxidant Activity of Cirsium englerianum (Asteraceae), an Endemic Plant to Ethiopia","publication_year":2021,"publication_date":"2021-07-01","ids":{"openalex":"https://openalex.org/W3168322326","doi":"https://doi.org/10.22127/rjp.2021.273419.1680","mag":"3168322326"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:edb192b772ae417c8124f6a1091597c6","doi":"https://doi.org/10.22127/rjp.2021.273419.1680","is_oa":false,"landing_page_url":"https://doaj.org/article/edb192b772ae417c8124f6a1091597c6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Journal of Pharmacognosy, Vol 8, Iss 3, Pp 5-12 (2021)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.rjpharmacognosy.ir/article_129935_44058b577e6b7ddb7df3a12da65f573d.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112371740","display_name":"Mesfin Bibiso","orcid":"https://orcid.org/0000-0001-9005-6865","observed_orcids":["https://orcid.org/0000-0001-9005-6865"]},"institutions":[{"id":"https://openalex.org/I4210101494","display_name":"Wolaita Sodo University","ror":"https://ror.org/0106a2j17","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210101494"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Mesfin Bibiso","raw_affiliation_strings":["Department of Chemistry, College of Natural and Computational Science, Wolaita Sodo University, Sodo, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, College of Natural and Computational Science, Wolaita Sodo University, Sodo, Ethiopia","institution_ids":["https://openalex.org/I4210101494"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038731444","display_name":"Mathewos Anza","orcid":"https://orcid.org/0000-0002-5141-599X","observed_orcids":["https://orcid.org/0000-0002-5141-599X"]},"institutions":[{"id":"https://openalex.org/I4210101494","display_name":"Wolaita Sodo University","ror":"https://ror.org/0106a2j17","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210101494"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Mathewos Anza","raw_affiliation_strings":["Department of Chemistry, College of Natural and Computational Science, Wolaita Sodo University, Sodo, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, College of Natural and Computational Science, Wolaita Sodo University, Sodo, Ethiopia","institution_ids":["https://openalex.org/I4210101494"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022716716","display_name":"Bereket Alemayehu","orcid":"https://orcid.org/0000-0001-8398-5164","observed_orcids":["https://orcid.org/0000-0001-8398-5164","https://orcid.org/0000-0003-2327-6969"]},"institutions":[{"id":"https://openalex.org/I4210101494","display_name":"Wolaita Sodo University","ror":"https://ror.org/0106a2j17","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210101494"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Bereket Alemayehu","raw_affiliation_strings":["Department of Biology, College of Natural and Computational Science, Wolaita Sodo University, Sodo, Ethiopia"],"raw_orcid":"https://orcid.org/0000-0001-8398-5164","affiliations":[{"raw_affiliation_string":"Department of Biology, College of Natural and Computational Science, Wolaita Sodo University, Sodo, Ethiopia","institution_ids":["https://openalex.org/I4210101494"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210101494"],"apc_list":null,"apc_paid":null,"fwci":0.1445,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.40187946,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"8","issue":"3","first_page":"5","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.35499998927116394,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.35499998927116394,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.2919999957084656,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.2685999870300293,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asteraceae","display_name":"Asteraceae","score":0.734000027179718},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.656000018119812},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.8180000185966492},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":1.0},{"id":"https://openalex.org/keywords/stigmasterol","display_name":"stigmasterol","score":0.8460000157356262},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.7749999761581421},{"id":"https://openalex.org/keywords/root-extract","display_name":"root extract","score":0.6930000185966492},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.7639999985694885},{"id":"https://openalex.org/keywords/dpph-radical-scavenging-activity","display_name":"DPPH radical scavenging","score":0.8579999804496765},{"id":"https://openalex.org/keywords/bacillus-cereus","display_name":"Bacillus cereus","score":0.828000009059906},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9980000257492065},{"id":"https://openalex.org/keywords/salmonella-enterica-serovar-typhi","display_name":"Salmonella typhi","score":0.9660000205039978}],"concepts":[{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.7676616311073303},{"id":"https://openalex.org/C2778016309","wikidata":"https://www.wikidata.org/wiki/Q425004","display_name":"Stigmasterol","level":2,"score":0.664903998374939},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6096659898757935},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.5542299151420593},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5348749160766602},{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.5222814083099365},{"id":"https://openalex.org/C2776593056","wikidata":"https://www.wikidata.org/wiki/Q415945","display_name":"Phytol","level":2,"score":0.5062093138694763},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4762706458568573},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.43696317076683044},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.358822226524353},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3369358777999878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2356245219707489},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.17722606658935547},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13774004578590393},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.10557252168655396},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07484400272369385},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:doaj.org/article:edb192b772ae417c8124f6a1091597c6","doi":"https://doi.org/10.22127/rjp.2021.273419.1680","is_oa":false,"landing_page_url":"https://doaj.org/article/edb192b772ae417c8124f6a1091597c6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Journal of Pharmacognosy, Vol 8, Iss 3, Pp 5-12 (2021)","raw_type":"article"},{"id":"mag:3168322326","doi":"https://doi.org/10.22127/rjp.2021.273419.1680","is_oa":true,"landing_page_url":"http://www.rjpharmacognosy.ir/article_129935_44058b577e6b7ddb7df3a12da65f573d.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764918579","display_name":"Research journal of pharmacognosy","issn_l":"2345-4458","issn":["2345-4458"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319078","host_organization_name":"Iranian Society of Pharmacognosy","host_organization_lineage":["https://openalex.org/P4310319078"],"host_organization_lineage_names":["Iranian Society of Pharmacognosy"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Research journal of pharmacognosy","raw_type":null}],"best_oa_location":{"id":"mag:3168322326","doi":"https://doi.org/10.22127/rjp.2021.273419.1680","is_oa":true,"landing_page_url":"http://www.rjpharmacognosy.ir/article_129935_44058b577e6b7ddb7df3a12da65f573d.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764918579","display_name":"Research journal of pharmacognosy","issn_l":"2345-4458","issn":["2345-4458"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319078","host_organization_name":"Iranian Society of Pharmacognosy","host_organization_lineage":["https://openalex.org/P4310319078"],"host_organization_lineage_names":["Iranian Society of Pharmacognosy"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Research journal of pharmacognosy","raw_type":null},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1967625763","https://openalex.org/W1993317383","https://openalex.org/W2005222601","https://openalex.org/W2038306434","https://openalex.org/W2040402086","https://openalex.org/W2061479778","https://openalex.org/W2077013120","https://openalex.org/W2102668570","https://openalex.org/W2118475570","https://openalex.org/W2149176501","https://openalex.org/W2162532280","https://openalex.org/W2187729166","https://openalex.org/W2571053339","https://openalex.org/W2912717819","https://openalex.org/W3011719258"],"related_works":["https://openalex.org/W1919754184","https://openalex.org/W2267049284","https://openalex.org/W2762705190","https://openalex.org/W3118520450","https://openalex.org/W4399292373","https://openalex.org/W2757291022","https://openalex.org/W3085214450","https://openalex.org/W2000396895","https://openalex.org/W4387772880","https://openalex.org/W2996100820"],"abstract_inverted_index":{"Background":[0],"and":[1,22,63,69,98,122,139,160,168,186,227,248,257],"objectives:":[2],"Cirsium":[3],"englerianum":[4],"(Asteraceae)":[5],"is":[6,14],"an":[7],"endemic":[8],"medicinal":[9],"plant":[10,223],"to":[11,16,31,50,59,73,84,213],"Ethiopia.":[12],"It":[13],"used":[15,58,72],"treat":[17],"skin":[18],"infection,":[19],"snake":[20],"bite":[21],"cough.":[23],"The":[24,101,143,201,239],"aim":[25],"of":[26,35,38,76,117,132,192,198,216,221],"the":[27,33,52,61,64,77,125,150,177,208,233],"present":[28],"study":[29],"was":[30,57,82,92,105,146,205],"evalute":[32,85],"bioactivity":[34],"root":[36,127],"extracts":[37],"C.":[39],"englerianum.":[40],"Methods:":[41],"Phythochemical":[42],"screening":[43,113],"tests":[44,114],"were":[45,71,230],"employed":[46],"by":[47,94,107],"standard":[48],"protocols":[49],"identifiy":[51],"phythochemicals.":[53],"Column":[54,129],"chromatographic":[55,130],"separation":[56,131],"isolate":[60],"compounds":[62],"spectroscopic":[65],"techniques":[66],"(IR,":[67],"NMR":[68],"ESMS)":[70],"elucidtae":[74],"structures":[75],"compounds.":[78],"Disc":[79],"diffusion":[80],"technique":[81],"uesd":[83],"antibacterial":[86,247],"activity.":[87,261],"In":[88,171],"vitro":[89,172],"antioxidant":[90,173,188,249],"activity":[91,174,189,250],"assessed":[93],"1,":[95],"1-diphenyl-2-picrylhydrazyl":[96],"(DPPH),":[97],"phosphomolybdenun":[99],"assays.":[100],"total":[102,187,202],"flavonoids":[103,123],"content":[104,204],"determined":[106],"aluminium":[108],"chloride":[109],"method.":[110],"Results:":[111],"Phytochemical":[112],"revealed":[115],"presence":[116],"alkaloids,":[118],"steroids,":[119],"terpenoids,":[120],"tannins,":[121],"in":[124,207],"acetone":[126,144,178,243],"extract.":[128,224],"chloroform/methanol":[133],"(1:1)":[134],"extract":[135,145,179,244],"offered":[136],"stigmasterol":[137],"(1),":[138],"stigmasteryl":[140,228],"stearate":[141,229],"(2).":[142],"potentially":[147],"effective":[148],"against":[149],"tested":[151],"bacterial":[152],"strains":[153],"(Bacillus":[154],"cereus,":[155],"Staphylococcus":[156],"aureus,":[157],"Escherichia":[158],"coli":[159],"Salmonella":[161],"typhi)":[162],"at":[163],"all":[164],"concentrations":[165],"(25,":[166],"50":[167],"100":[169],"mg/mL).":[170],"attributed":[175],"that":[176,242],"showed":[180],"DPPH":[181],"scavenging":[182,260],"(IC50":[183],"=154.44\u00b174":[184],"\u00b5g/mL)":[185],"(8.24\u00b10.9":[190],"mg":[191],"ascorbic":[193],"acid":[194],"equivalent":[195],"per":[196,219],"gram":[197,220],"dry":[199,222],"extract).":[200],"flavonoid":[203],"observed":[206],"range":[209],"from":[210,236],"5.88":[211],"\u00b10.21":[212],"8.24\u00b10.9":[214],"milligrams":[215],"catechin":[217],"equivalents":[218],"Conclusion:":[225],"Stigmasterol":[226],"reported":[231],"for":[232],"first":[234],"time":[235],"this":[237],"plant.":[238],"results":[240],"proved":[241],"exhibited":[245],"potential":[246],"which":[251],"correlated":[252],"with":[253],"inhibition":[254],"zone":[255],"diameter,":[256],"free":[258],"radical":[259]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2021-06-22T00:00:00"}