{"id":"https://openalex.org/W3168085166","doi":"https://doi.org/10.21608/ajsr.2020.177501","title":"Bioinformatic study on Some Phenyl piperidine derivatives as novel serotonin transporter (SERT) inhibitors for antipsychotic agents targeting Depression","display_name":"Bioinformatic study on Some Phenyl piperidine derivatives as novel serotonin transporter (SERT) inhibitors for antipsychotic agents targeting Depression","publication_year":2020,"publication_date":"2020-04-01","ids":{"openalex":"https://openalex.org/W3168085166","doi":"https://doi.org/10.21608/ajsr.2020.177501","mag":"3168085166"},"language":"en","primary_location":{"id":"doi:10.21608/ajsr.2020.177501","doi":"https://doi.org/10.21608/ajsr.2020.177501","is_oa":true,"landing_page_url":"https://doi.org/10.21608/ajsr.2020.177501","pdf_url":"https://ajsr.journals.ekb.eg/article_177501_a8c250e2bb5e430a6b2702cb81ae1495.pdf","source":{"id":"https://openalex.org/S4210209995","display_name":"The Arab Journal of Scientific Research","issn_l":"2537-0367","issn":["2537-0367","2537-0375"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Arab Journal of Scientific Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ajsr.journals.ekb.eg/article_177501_a8c250e2bb5e430a6b2702cb81ae1495.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052578002","display_name":"Sabitu Babatunde Olasupo","orcid":"https://orcid.org/0000-0003-1946-7404","observed_orcids":["https://orcid.org/0000-0003-1946-7404"]},"institutions":[{"id":"https://openalex.org/I4405285580","display_name":"National Agency for Food and Drug Administration and Control","ror":"https://ror.org/05qeath86","country_code":"NG","type":"government","lineage":["https://openalex.org/I4405285580"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Sabitu Olasupo","raw_affiliation_strings":["1National Agency for Food and Drug Administration and Control (NAFDAC)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1National Agency for Food and Drug Administration and Control (NAFDAC)","institution_ids":["https://openalex.org/I4405285580"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021521217","display_name":"Adamu uzariu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Adamu uzariu","raw_affiliation_strings":["Department of Chemistry, Ahmadu Bello University Zaria, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Ahmadu Bello University Zaria, Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032573298","display_name":"Gideon Adamu Shallangwa","orcid":"https://orcid.org/0000-0002-0700-9898","observed_orcids":["https://orcid.org/0000-0002-0700-9898"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Gideon Shallangwa","raw_affiliation_strings":["Department of Chemistry, Ahmadu Bello University Zaria, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Ahmadu Bello University Zaria, Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111658500","display_name":"Sani Uba","orcid":"https://orcid.org/0000-0001-9595-6897","observed_orcids":["https://orcid.org/0000-0001-9595-6897"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Sani Uba","raw_affiliation_strings":["Department of Chemistry, Ahmadu Bello University Zaria, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Ahmadu Bello University Zaria, Nigeria","institution_ids":["https://openalex.org/I12789410"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":"4","first_page":"1","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13454","display_name":"Phenothiazines and Benzothiazines Synthesis and Activities","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonin-transporter-inhibitors","display_name":"serotonin transporter inhibitors","score":0.9470000267028809},{"id":"https://openalex.org/keywords/serotonin-transporter","display_name":"serotonin transporter","score":0.7260000109672546},{"id":"https://openalex.org/keywords/antipsychotic-drugs","display_name":"antipsychotic drugs","score":0.8989999890327454},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.949999988079071},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.6420000195503235},{"id":"https://openalex.org/keywords/drug-design","display_name":"drug design","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C2778897192","wikidata":"https://www.wikidata.org/wiki/Q410142","display_name":"Serotonin transporter","level":4,"score":0.7894935607910156},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5444021224975586},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.5433022379875183},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.5322525501251221},{"id":"https://openalex.org/C2781462491","wikidata":"https://www.wikidata.org/wiki/Q410234","display_name":"Piperidine","level":2,"score":0.5278962254524231},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5120413899421692},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.48158836364746094},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.4124250113964081},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39526981115341187},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3548154830932617},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3548124432563782},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2352089285850525},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21287131309509277},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14792588353157043},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.14430326223373413},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06983783841133118},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21608/ajsr.2020.177501","doi":"https://doi.org/10.21608/ajsr.2020.177501","is_oa":true,"landing_page_url":"https://doi.org/10.21608/ajsr.2020.177501","pdf_url":"https://ajsr.journals.ekb.eg/article_177501_a8c250e2bb5e430a6b2702cb81ae1495.pdf","source":{"id":"https://openalex.org/S4210209995","display_name":"The Arab Journal of Scientific Research","issn_l":"2537-0367","issn":["2537-0367","2537-0375"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Arab Journal of Scientific Research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.21608/ajsr.2020.177501","doi":"https://doi.org/10.21608/ajsr.2020.177501","is_oa":true,"landing_page_url":"https://doi.org/10.21608/ajsr.2020.177501","pdf_url":"https://ajsr.journals.ekb.eg/article_177501_a8c250e2bb5e430a6b2702cb81ae1495.pdf","source":{"id":"https://openalex.org/S4210209995","display_name":"The Arab Journal of Scientific Research","issn_l":"2537-0367","issn":["2537-0367","2537-0375"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Arab Journal of Scientific Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3168085166.pdf","grobid_xml":"https://content.openalex.org/works/W3168085166.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3036869634","https://openalex.org/W3081077707","https://openalex.org/W2505609562","https://openalex.org/W2416915734","https://openalex.org/W2951952095","https://openalex.org/W1978424060","https://openalex.org/W4213307126","https://openalex.org/W2462774697","https://openalex.org/W2542022292","https://openalex.org/W2951665329"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-06-22T00:00:00"}